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- Yang, Vicky K., et al. Show all 5 Authors
- Journal of veterinary cardiology 2015 v.17 no.3 pp. 210-215
- animal models; antagonists; appetite; body condition; cachexia; clinical trials; dogs; drugs; heart failure; humans; lean body mass; muscles; myostatin; quality of life
- ... Cardiac cachexia, a loss of lean body mass caused by heart disease, often accompanies congestive heart failure (CHF). Blocking myostatin, which is a protein that inhibits muscle growth, appears to greatly enhance muscle size and strength in rodent models and human clinical trials. The objective of this study was to evaluate a dog-specific myostatin antagonist (CAP-031) in a pilot study to test its ...
- Yang, Vicky K., et al. Show all 7 Authors
- Journal of veterinary cardiology 2015 v.17 pp. S341
- cats; disease severity; heart failure; hospitals; natriuretic peptides; pet ownership; quality of life; questionnaires
- ... To evaluate the responsiveness and optimal timing of a validated health-related quality of life questionnaire, and to assess the relationship between quality of life, severity of disease, and N-terminal pro B-type natriuretic peptide (NT-proBNP) in cats with acute congestive heart failure (CHF).Thirty client-owned cats with acute CHF.Echocardiography, International Small Animal Cardiac Health Coun ...