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1. Association of Antioxidants Use with All-Cause and Cause-Specific Mortality: A Prospective Study of the UK Biobank

Author:
Behrendt, Inken; Eichner, Gerrit; Fasshauer, Mathias
Source:
Antioxidants 2020 v.9 no.12
ISSN:
2076-3921
Subject:
age; antioxidants; ascorbic acid; confidence interval; models; mortality; population; prospective studies; respiratory tract diseases; risk; selenium; testing; vitamin E; zinc
Abstract:
... Prospective studies and randomized controlled trials elucidating the impact of antioxidants supplementation on mortality risk are inconclusive. The present analysis determined association between regular antioxidants use and all-cause (primary objective), as well as cause-specific, mortality in 345,626 participants of the UK Biobank cohort using Cox proportional hazard models. All models were adju ...
DOI:
10.3390/antiox9121287

2. Sociodemographic factors associated with low intake of bioavailable iron in preschoolers: National Health and Nutrition Survey 2012, Mexico

Author:
Venegas-Aviles, Yazmín; Rodríguez-Ramírez, Sonia; Monterrubio-Flores, Eric; García-Guerra, Armando
Source:
Nutrition journal 2020 v.19 no.1 pp. 57
ISSN:
1475-2891
Subject:
age; algorithms; area; ascorbic acid; bioavailability; blood serum; calcium; cross-sectional studies; experimental design; ferritin; heme; information; iron; meat consumption; national surveys; nutrition surveys; population; preschool children; regression analysis; risk; rural areas; sociodemographic characteristics; socioeconomic status; urban areas; Mexico
Abstract:
... BACKGROUND: Children < 5 years of age are at risk of developing an iron deficiency due to a low intake of bioavailable iron (FeBio). Few studies have estimated dietary FeBio in children at a national level in relation to sociodemographic characteristics. This study aimed to estimate FeBio intake and its association with sociodemographic factors among Mexican children aged 12–59 months. METHODS: A ...
DOI:
10.1186/s12937-020-00567-3

3. Clinical and Molecular-Genetic Insights into the Role of Oxidative Stress in Diabetic Retinopathy: Antioxidant Strategies and Future Avenues

Author:
Sanz-González, Silvia M.; García-Medina, José J.; Zanón-Moreno, Vicente; López-Gálvez, María I.; Galarreta-Mira, David; Duarte, Lilianne; Valero-Velló, Mar; Ramírez, Ana I.; Arévalo, J. Fernando; Pinazo-Durán, María D.; on behalf of the Valencia Study Group on Diabetic Retinopathy (VSDR) Report number 4,
Source:
Antioxidants 2020 v.9 no.11
ISSN:
2076-3921
Subject:
antioxidant activity; ascorbic acid; blindness; blood composition; case-control studies; diabetic retinopathy; disease control; eyes; gene expression regulation; genes; malondialdehyde; omega-3 fatty acids; oxidative stress; patients; reactive oxygen species; risk; solutes; thiobarbituric acid-reactive substances
Abstract:
... Reactive oxygen species (ROS) overproduction and ROS-signaling pathways activation attack the eyes. We evaluated the oxidative stress (OS) and the effects of a daily, core nutritional supplement regimen containing antioxidants and omega 3 fatty acids (A/ω3) in type 2 diabetics (T2DM). A case-control study was carried out in 480 participants [287 T2DM patients with (+)/without (-) diabetic retinopa ...
DOI:
10.3390/antiox9111101

4. An innovative design and application of natural antimicrobial gelatin based filling to control risk of listeriosis from caramel apples

Author:
Kavur, Pelin Barış; Yemenicioğlu, Ahmet
Source:
Food hydrocolloids 2020 v.107 pp. 105938
ISSN:
0268-005X
Subject:
Listeria; antibrowning agents; apple juice; apples; ascorbic acid; candy; cold storage; crop production; discoloration; gelatin; gelation; hydrocolloids; inulin; listeriosis; lysozyme; mechanical testing; nisin; risk; soy protein; sucrose; water activity; water holding capacity
Abstract:
... The aim of this study is to design and apply antimicrobial gelatin based filling with an innovative method in production of safe caramel apples that caused deadly listeriosis cases. For this purpose, water holding capacity and mechanical stability of gelatin (GEL) gels were improved by incorporation of soy proteins (SP) and inulin (IN), respectively. The water activity (aw) of gels were also reduc ...
DOI:
10.1016/j.foodhyd.2020.105938

5. Leaching of exhausted LNCM cathode batteries in ascorbic acid lixiviant: a green recycling approach, reaction kinetics and process mechanism

Author:
Munir, Huma; Srivastava, Rajiv Ranjan; Kim, Hyunjung; Ilyas, Sadia; Khosa, Muhammad Kaleem; Yameen, Basit
Source:
Journal of chemical technology and biotechnology 2020 v.95 no.8 pp. 2286-2294
ISSN:
0268-2575
Subject:
acids; activation energy; agitation; ascorbic acid; biodegradability; biotechnology; cathodes; cobalt; degradation; density; empirical models; face; kinetics; leaching; lithium; lithium batteries; metallurgy; nickel; pulp; reaction kinetics; recycling; reducing agents; risk; supply; temperature; toxicity
Abstract:
... BACKGROUND: Critical metals (lithium, cobalt and nickel) used in Li‐ion batteries have been estimated to face a supply crunch by the end of 2020 due to their limited natural reserves and complex metallurgy. A green recycling approach to treat the exhausted batteries may potentially mitigate supply risks of metals and environmental burden of metal toxicity. RESULTS: The maiden application of bio‐pr ...
DOI:
10.1002/jctb.6418

6. Studies of combined NO-eluting/CD47-modified polyurethane surfaces for synergistic enhancement of biocompatibility

Author:
Zhang, Qi; Stachelek, Stanley J.; Inamdar, Vaishali V.; Alferiev, Ivan; Nagaswami, Chandrasekaran; Weisel, John W.; Hwang, Jeong Hyun; Meyerhoff, Mark E.
Source:
Colloids and surfaces 2020 v.192 pp. 111060
ISSN:
0927-7765
Subject:
amino acids; ascorbic acid; biocompatibility; blood platelets; catheters; composite polymers; models; nitric oxide; peptides; polyurethanes; risk; silicone; thrombosis; transmembrane proteins
Abstract:
... The blood compatibility of various intravascular (IV) devices (e.g., catheters, sensors, etc.) is compromised by activation of platelets that can cause thrombus formation and device failure. Such devices also carry a high risk of microbial infection. Recently, nitric oxide (NO) releasing polymers/devices have been proposed to reduce these clinical problems. CD47, a ubiquitously expressed transmemb ...
DOI:
10.1016/j.colsurfb.2020.111060

7. Effects of ozone and chlorine washes and subsequent cold storage on microbiological quality and shelf life of fresh parsley leaves

Author:
Karaca, Hakan; Velioglu, Y. Sedat
Source:
Lebensmittel-Wissenschaft + [i.e. und] Technologie 2020 v.127 pp. 109421
ISSN:
0023-6438
Subject:
Escherichia coli; Listeria innocua; antioxidant activity; antioxidants; ascorbic acid; chlorine; chlorophyll; cold storage; color; food safety; leaves; microbiological quality; microorganisms; ozone; parsley; pigments; risk; shelf life
Abstract:
... In this study, we evaluated the effects of ozone and chlorine washes on the inactivation of Escherichia coli and Listeria innocua and on color pigments and antioxidant compounds of fresh parsley leaves. The growth of the microorganisms and the changes in pigments and antioxidant compounds of the leaves during subsequent cold storage for 15 days were also investigated. The microbial reductions obta ...
DOI:
10.1016/j.lwt.2020.109421

8. Vitamin C in Health and Disease: A Companion Animal Focus

Author:
Gordon, Daniel S.; Rudinsky, Adam J.; Guillaumin, Julien; Parker, Valerie J.; Creighton, Karina J.
Source:
Topics in companion animal medicine 2020 v.39 pp. 100432
ISSN:
1938-9736
Subject:
adverse effects; ascorbic acid; biochemical pathways; catecholamines; cats; dogs; humans; intravenous injection; liver; medicine; oxidative stress; patients; pets; risk; septic shock; tissues; vasopressin
Abstract:
... Vitamin C is synthesized in the liver in most species, including dogs and cats, and is widely distributed through body tissues. Vitamin C has an important physiologic role in numerous metabolic functions including tissue growth and maintenance, amelioration of oxidative stress, and immune regulation. It is also a co-factor in the production of important substances such as catecholamines and vasopr ...
DOI:
10.1016/j.tcam.2020.100432

9. Acute Effects of Three Different Meal Patterns on Postprandial Metabolism in Older Individuals with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Controlled Crossover Trial

Author:
Schönknecht, Yannik B.; Crommen, Silke; Stoffel‐Wagner, Birgit; Coenen, Martin; Fimmers, Rolf; Holst, Jens J.; Simon, Marie‐Christine; Stehle, Peter; Egert, Sarah
Source:
Molecular nutrition & food research 2020 v.64 no.9 pp. e1901035
ISSN:
1613-4125
Subject:
Mediterranean diet; Western diets; acute effects; antioxidants; ascorbic acid; blood sampling; cross-over studies; fasting; glucagon-like peptide 1; glucose; hyperglycemia; hyperlipidemia; inflammation; insulin; interleukin-1beta; interleukin-6; metabolism; overweight; oxidation; phenotype; risk; triacylglycerols
Abstract:
... SCOPE: The aim of this study is to investigate acute postprandial responses to intake of meals typical for Mediterranean and Western diets. METHODS: In a randomized crossover design, overweight and obese participants with a risk phenotype for cardiometabolic diseases consumed three different isoenergetic meals: Western diet‐like high‐fat (WDHF), Western diet‐like high‐carbohydrate (WDHC), and Medi ...
DOI:
10.1002/mnfr.201901035

10. A critical review of mercury speciation, bioavailability, toxicity and detoxification in soil-plant environment: Ecotoxicology and health risk assessment

Author:
Natasha,; Shahid, Muhammad; Khalid, Sana; Bibi, Irshad; Bundschuh, Jochen; Khan Niazi, Nabeel; Dumat, Camille
Source:
The Science of the total environment 2020 v.711 pp. 134749
ISSN:
0048-9697
Subject:
antioxidants; ascorbate peroxidase; ascorbic acid; bioavailability; carcinogenicity; catalase; chemical speciation; ecotoxicology; food chain; food plants; glutathione; glutathione peroxidase; health effects assessments; humans; mercury; meta-analysis; mutagens; oxidative stress; peroxidase; phytochelatins; phytotoxicity; plant tissues; pollution; proline; risk; soil; students; superoxide dismutase
Abstract:
... Environmental contamination by a non-essential and non-beneficial, although potentially toxic mercury (Hg), is becoming a great threat to the living organisms at a global scale. Owing to its various uses in numerous industrial processes, high amount of Hg is released into different environmental compartments. Environmental Hg contamination can result in food chain contamination, especially due to ...
DOI:
10.1016/j.scitotenv.2019.134749

11. Effects of Micronutrients or Conditional Amino Acids on COVID-19-Related Outcomes: An Evidence Analysis Center Scoping Review

Author:
Rozga, Mary; Cheng, Feon W.; Moloney, Lisa; Handu, Deepa
Source:
Journal of the Academy of Nutrition and Dietetics 2020
ISSN:
2212-2672
Subject:
COVID-19 infection; acute respiratory distress syndrome; adults; arginine; ascorbic acid; cholecalciferol; databases; diet therapy; dietitians; disease severity; glutamine; intravenous injection; nutrient deficiencies; nutritionists; patients; pneumonia; risk; systematic review; vitamin E; zinc sulfate
Abstract:
... Recent narrative reviews have described the potential efficacy of providing individuals infected with coronavirus disease 2019 (COVID-19) with additional micronutrients to reduce disease severity. Although there are compelling reasons why providing additional micronutrients or conditional amino acids may affect COVID-19-related outcomes, evidence is lacking. The objective of this scoping review is ...
DOI:
10.1016/j.jand.2020.05.015

12. The relationship between dietary antioxidant intake and physical activity rate with nonalcoholic fatty liver disease (NAFLD): A case – Control study

Author:
Lotfi, Ali; Saneei, Parvane; Hekmatdost, Azita; Salehisahlabadi, Ammar; Shiranian, Afshin; Ghiasvand, Reza
Source:
Clinical nutrition ESPEN 2019 v.34 pp. 45-49
ISSN:
2405-4577
Subject:
adults; alpha-tocopherol; antioxidants; ascorbic acid; body mass index; fatty liver; food frequency questionnaires; food intake; hematologic tests; hip circumference; nutrition risk assessment; patients; physical activity; prospective studies; radiology; risk; risk reduction; ultrasonography; vitamin A; vitamin D; waist circumference; women
Abstract:
... Although dietary intakes, especially micronutrients, can be associated with the severity of nonalcoholic fatty liver disease (NAFLD), investigations on the amount of vitamins and antioxidants consumption and their relationship with NAFLD are very limited and incomplete. Therefore, we decided to investigate the relationship between antioxidant compounds intake and physical activity rate with NAFLD. ...
DOI:
10.1016/j.clnesp.2019.09.004

13. Time trends in nutrient intake and dietary patterns among five birth cohorts of 70-year-olds examined 1971–2016: results from the Gothenburg H70 birth cohort studies, Sweden

Author:
Samuelsson, Jessica; Rothenberg, Elisabet; Lissner, Lauren; Eiben, Gabriele; Zettergren, Anna; Skoog, Ingmar
Source:
Nutrition journal 2019 v.18 no.1 pp. 66
ISSN:
1475-2891
Subject:
Dietary Guidelines; alcohol drinking; alcohols; ascorbic acid; beers; body weight; chi-square distribution; cohort studies; diet history; eating habits; elderly; fish; folic acid; fruits; health services; linear models; men; nutrient density; nuts; portion size; protein intake; risk; seafoods; seeds; t-test; vegetables; vitamin D; whole grain foods; wines; women; Sweden
Abstract:
... BACKGROUND: Nutrition is a key factor in healthy ageing but there are still gaps in knowledge about risk- and protective factors linking diet and healthy ageing. The aim of this study was to investigate time trends in dietary patterns and nutrient intake in an older population, in order to increase the understanding of whether dietary recommendations are followed and if nutrient needs are met. MET ...
DOI:
10.1186/s12937-019-0493-8
PubMed:
31694635
PubMed Central:
PMC6836447

14. The Ageing Process Affects the Antioxidant Defences and the Poly (ADPribosyl)ation Activity in <em>Cistus Incanus</em> L. Leaves

Author:
Arena, Carmen; Vitale, Luca; Bianchi, Anna Rita; Mistretta, Carmela; Vitale, Ermenegilda; Parisi, Costantino; Guerriero, Giulia; Magliulo, Vincenzo; De Maio, Anna
Source:
Antioxidants 2019 v.8 no.11
ISSN:
2076-3921
Subject:
Cistus incanus; DNA; NAD ADP-ribosyltransferase; alpha-tocopherol; antioxidant activity; ascorbic acid; catalase; cell structures; chlorophyll; developmental stages; enzyme activity; fluorescence; genomics; glutathione transferase; leaves; lipids; peroxidase; photochemistry; photosynthesis; proteins; reactive oxygen species; risk; spectrophotometers; superoxide dismutase; tissues
Abstract:
... The ageing process in living organisms is characterised by the accumulation of several deleterious changes occurring in cells and tissues. The increase of reactive oxygen species with the advancement of age is responsible for the oxidative damage to proteins, lipids and DNA, enhancing the risk of diseases. The antioxidant response and the activation of the poly(ADP-ribosyl)ation process represent ...
DOI:
10.3390/antiox8110528
PubMed:
31698730
PubMed Central:
PMC6912739

15. Vitamin C and Neutrophil Function: Findings from Randomized Controlled Trials

Author:
Liugan, Mikee; Carr, Anitra C.
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
antioxidant enzymes; apoptosis; ascorbic acid; athletes; chemotaxis; databases; enzyme activity; exercise; immune response; intravenous injection; myocardial infarction; neutrophils; oxidants; patients; phagocytosis; randomized clinical trials; risk; systematic review; vitamin status; volunteers
Abstract:
... Vitamin C is known to support immune function and is accumulated by neutrophils to millimolar intracellular concentrations suggesting an important role for the vitamin in these cells. In this review, the effects of vitamin C, as a mono- or multi-supplement therapy, on neutrophil function were assessed by conducting a systematic review of randomized controlled trials (RCTs). Specifically, trials wh ...
DOI:
10.3390/nu11092102
PubMed:
31487891
PubMed Central:
PMC6770220

16. Biogeochemistry of antimony in soil-plant system: Ecotoxicology and human health

Author:
Natasha,; Shahid, Muhammad; Khalid, Sana; Dumat, Camille; Pierart, Antoine; Niazi, Nabeel Khan
Source:
Applied geochemistry 2019 v.106 pp. 45-59
ISSN:
0883-2927
Subject:
antimony; antioxidants; ascorbate peroxidase; ascorbic acid; bioaccumulation; biogeochemistry; carcinogenicity; catalase; chemical speciation; ecotoxicology; food chain; food plants; glutathione; glutathione peroxidase; grains; heavy metals; human health; mutagens; oxidative stress; peroxidase; phytochelatins; phytotoxicity; plant tissues; pollution; proline; risk; soil; superoxide dismutase; transport proteins; vegetables
Abstract:
... Environmental contamination by antimony (Sb), a non-essential and non-beneficial metalloid, is a great threat to living organisms at a global scale. Owing to its various uses in numerous industrial processes, Sb is released into different environmental compartments every year. Environmental Sb contamination can result in food chain bioaccumulation, especially due to its uptake and accumulation in ...
DOI:
10.1016/j.apgeochem.2019.04.006

17. Dietary and circulating vitamin C, vitamin E, β-carotene and risk of total cardiovascular mortality: a systematic review and dose–response meta-analysis of prospective observational studies

Author:
Jayedi, Ahmad; Rashidy-Pour, Ali; Parohan, Mohammad; Zargar, Mahdieh Sadat; Shab-Bidar, Sakineh
Source:
Public health nutrition 2019 v.22 no.10 pp. 1872-1887
ISSN:
1475-2727
Subject:
alpha-tocopherol; antioxidants; ascorbic acid; beta-carotene; biomarkers; cohort studies; dose response; food intake; meta-analysis; mortality; observational studies; risk; risk estimate; systematic review
Abstract:
... The present review aimed to quantify the association of dietary intake and circulating concentration of major dietary antioxidants with risk of total CVD mortality. Systematic review and meta-analysis. Systematic search in PubMed and Scopus, up to October 2017. Prospective observational studies reporting risk estimates of CVD mortality across three or more categories of dietary intakes and/or circ ...
DOI:
10.1017/S1368980018003725
PubMed:
30630552 30630552

18. Among the water-soluble vitamins, dietary intakes of vitamins C, B₂ and folate are associated with the reduced risk of diabetes in Japanese women but not men

Author:
Eshak, Ehab S.; Iso, Hiroyasu; Muraki, Isao; Tamakoshi, Akiko
Source:
The British journal of nutrition 2019 v.121 no.12 pp. 1357-1364
ISSN:
1475-2662
Subject:
Japanese people; antioxidant activity; ascorbic acid; body mass index; folic acid; food intake; men; noninsulin-dependent diabetes mellitus; prospective studies; protective effect; pyridoxine; regression analysis; riboflavin; risk; risk reduction; smoking (habit); thiamin; women
Abstract:
... Recent studies have shown that micronutrients are involved in the pathology of type 2 diabetes. Antioxidant effects of vitamins C and B₂ and homocysteine-lowering effects of vitamins B₆, folate and B₁₂ may have protective roles. However, a few reports have investigated the association between dietary water-soluble vitamin intakes and risk of diabetes. In a prospective study encompassing 19 168 hea ...
DOI:
10.1017/S000711451900062X

19. Glycemic Control during Pregnancy—A Predictor of Vitamin C Status at Labor in Type 1 Diabetic Women?

Author:
Juhl, Bente; Lauszus, Finn F.; Lykkesfeldt, Jens
Source:
Antioxidants 2019 v.8 no.6
ISSN:
2076-3921
Subject:
ascorbic acid; biomarkers; creatinine; cross-sectional studies; diabetes; fetal development; glycemic control; neonates; observational studies; pregnancy; pregnant women; regression analysis; risk; vitamin status
Abstract:
... Several experimental studies have suggested that vitamin C (vitC) deficiency during pregnancy may be detrimental to fetal development, and observational studies have shown that vitC status is lower during pregnancy and in people with diabetes. A cross-sectional study in pregnant type 1 diabetic women found that poor maternal vitC status was a significant predictor for obstetric complications of pr ...
DOI:
10.3390/antiox8060153
PubMed:
31159250
PubMed Central:
PMC6617071

20. Ultrasound-assisted fast preparation of low molecular weight fucosylated chondroitin sulfate with antitumor activity

Author:
Li, Junhui; Li, Shan; Wu, Limei; Yang, Huifang; Wei, Chaoyang; Ding, Tian; Linhardt, Robert J.; Zheng, Xiaoliang; Ye, Xingqian; Chen, Shiguo
Source:
Carbohydrate polymers 2019 v.209 pp. 82-91
ISSN:
0144-8617
Subject:
Isostichopus; anticoagulant activity; antineoplastic activity; antineoplastic agents; ascorbic acid; chondroitin sulfate; depolymerization; free radicals; fucose; functional foods; hemorrhage; high performance liquid chromatography; infrared spectroscopy; lung neoplasms; molecular weight; neoplasm cells; nuclear magnetic resonance spectroscopy; risk; temperature; ultrasonic treatment; ultrasonics
Abstract:
... Fucosylated chondroitin sulfate from sea cucumber Isostichopus badionotus (fCS-Ib) was depolymerized with an ultrasound-accelerated, metal-free Fenton chemistry, relying on H2O2/ascorbic acid redox system. Fragments of different molecular weights were obtained at different reaction temperatures, ascorbic acid concentrations and ultrasonic intensities. The structures of two typical depolymerized fr ...
DOI:
10.1016/j.carbpol.2018.12.061