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1. Aerosol infection of Balb/c mice with eastern equine encephalitis virus; susceptibility and lethality

Author:
Phelps, Amanda L.; O’Brien, Lyn M.; Eastaugh, Lin S.; Davies, Carwyn; Lever, Mark S.; Ennis, Jane; Zeitlin, Larry; Nunez, Alejandro; Ulaeto, David O.
Source:
Virology journal 2019 v.16 no.1 pp. 2
ISSN:
1743-422X
Subject:
Culicidae; Eastern equine encephalitis virus; aerosols; birds; blood; blood-brain barrier; brain; death; disease susceptibility; dose response; epizootic diseases; histopathology; horses; human diseases; humans; lethal dose 50; lungs; meningoencephalitis; mice; models; mortality; pathogenesis; signs and symptoms (animals and humans); spleen; viral load; virology; viruses; United States
Abstract:
... BACKGROUND: Eastern equine encephalitis virus is an alphavirus that naturally cycles between mosquitoes and birds or rodents in Eastern States of the US. Equine infection occurs by being bitten by cross-feeding mosquitoes, with a case fatality rate of up to 75% in humans during epizootic outbreaks. There are no licensed medical countermeasures, and with an anticipated increase in mortality when ex ...
DOI:
10.1186/s12985-018-1103-7

2. A gD&gC-substituted pseudorabies virus vaccine strain provides complete clinical protection and is helpful to prevent virus shedding against challenge by a Chinese pseudorabies variant

Author:
Zhang, Chuanjian; Liu, Yamei; Chen, Saisai; Qiao, Yongfeng; Guo, Mingpeng; Zheng, Yating; Xu, Mengwei; Wang, Zhisheng; Hou, Jibo; Wang, Jichun
Source:
BMC veterinary research 2019 v.15 no.1 pp. 2
ISSN:
1746-6148
Subject:
livestock and meat industry; Suid alphaherpesvirus 1; piglets; bacterial artificial chromosomes; vaccines; farms; Aujeszky disease; body temperature; disease control; homologous recombination; growth models; vaccination; genes; viral shedding; lungs; testes; mortality; signs and symptoms (animals and humans); China
Abstract:
... BACKGROUND: Since 2011, pseudorabies caused by a variant PRV has re-emerged in many Chinese Bartha-K61-vaccinated pig farms. An efficacious vaccine is necessary to control this disease. We described the construction of a gD&gC-substituted pseudorabies virus (PRV B-gD&gCS) from the Bartha-K61 (as backbone) and AH02LA strain (as template for gD and gC genes) through bacterial artificial chromosome ( ...
DOI:
10.1186/s12917-018-1766-8

3. Analysis of blood degradation products and ferritin in the cerebrospinal fluid of dogs with acute thoracolumbar intervertebral disk extrusion, a prospective pilot study

Author:
Bittermann, Sophie; Schild, Christof; Marti, Eliane; Mirkovitch, Jelena; Schweizer, Daniela; Henke, Diana
Source:
BMC veterinary research 2019 v.15 no.1 pp. 148
ISSN:
1746-6148
Subject:
absorption; arteritis; bilirubin; blood; cerebrospinal fluid; dogs; epilepsy; extrusion; ferritin; hemorrhage; intervertebral disks; magnetic resonance imaging; meningitis; signs and symptoms (animals and humans); spinal cord
Abstract:
... BACKGROUND: Hemorrhage in the spinal canal leads to further damage of the spinal cord influencing outcome in dogs with intervertebral disk (IVD) extrusion. The aim of the study was to evaluate blood degradation products and ferritin in the cerebrospinal fluid (CSF) of dogs with thoracolumbar IVD extrusion, and their association to clinical parameters and MRI findings. RESULTS: In the CSF of dogs w ...
DOI:
10.1186/s12917-019-1878-9

4. A novel Babesia sp. associated with clinical signs of babesiosis in domestic cats in South Africa

Author:
Bosman, Anna-Mari; Penzhorn, Barend L.; Brayton, Kelly A.; Schoeman, Tanya; Oosthuizen, Marinda C.
Source:
Parasites & vectors 2019 v.12 no.1 pp. 138
ISSN:
1756-3305
Subject:
Babesia microti; Chrysocyon brachyurus; DNA; Procyon lotor; animal pathogens; babesiosis; blood; blood sampling; cats; coasts; dogs; feral animals; microscopy; molecular cloning; new species; nucleic acid hybridization; phylogeny; ribosomal RNA; sequence analysis; signs and symptoms (animals and humans); ticks; type collections; Japan; Mozambique; South Africa; United States
Abstract:
... BACKGROUND: Feline babesiosis, sporadically reported from various countries, is of major clinical significance in South Africa, particularly in certain coastal areas. Babesia felis, B. leo, B. lengau and B. microti have been reported from domestic cats in South Africa. Blood specimens from domestic cats (n = 18) showing clinical signs consistent with feline babesiosis and confirmed to harbour Babe ...
DOI:
10.1186/s13071-019-3395-x

5. Antibiotic treatment triggers gut dysbiosis and modulates metabolism in a chicken model of gastro-intestinal infection

Author:
Le Roy, Caroline Ivanne; Woodward, Martin John; Ellis, Richard John; La Ragione, Roberto Marcello; Claus, Sandrine Paule
Source:
BMC veterinary research 2019 v.15 no.1 pp. 37
ISSN:
1746-6148
Subject:
Brachyspira pilosicoli; animal production; antibiotics; betaine; biochemical pathways; chickens; death; digestive system; dysbiosis; dysentery; energy metabolism; glucose; glycerol; high density lipoprotein; high-throughput nucleotide sequencing; intestinal microorganisms; models; nuclear magnetic resonance spectroscopy; pathogens; phenotype; production technology; ribosomal DNA; signs and symptoms (animals and humans); tiamulin; very low density lipoprotein; weight loss
Abstract:
... BACKGROUND: Infection of the digestive track by gastro-intestinal pathogens results in the development of symptoms ranging from mild diarrhea to more severe clinical signs such as dysentery, severe dehydration and potentially death. Although, antibiotics are efficient to tackle infections, they also trigger dysbiosis that has been suggested to result in variation in weight gain in animal productio ...
DOI:
10.1186/s12917-018-1761-0

6. A single nucleotide variant in the promoter region of the CCR5 gene increases susceptibility to arthritis encephalitis virus in goats

Author:
Colussi, Silvia; Desiato, Rosanna; Beltramo, Chiara; Peletto, Simone; Modesto, Paola; Maniaci, Maria Grazia; Campia, Valentina; Quasso, Antonio; Rosati, Sergio; Bertolotti, Luigi; Ru, Giuseppe; Acutis, Pier Luigi
Source:
BMC veterinary research 2019 v.15 no.1 pp. 230
ISSN:
1746-6148
Subject:
CCR5 receptor; Caprine arthritis encephalitis virus; Human immunodeficiency virus; Visna maedi virus; animal welfare; arthritis; chemokines; control methods; cross-sectional studies; encephalitis; genes; genetic variation; goats; herds; human diseases; humans; immunosuppression; mutation; promoter regions; risk; sheep; signs and symptoms (animals and humans); transcription (genetics); viruses
Abstract:
... BACKGROUND: The small ruminant lentiviruses (SRLVs) are a heterogeneous group of viruses that includes caprine arthritis encephalitis virus (CAEV) and Maedi-Visna virus (MVV). SRLVs affect the production and welfare of sheep and goats worldwide. There is currently no effective treatment. Their high mutation rate precludes vaccine development, making innovative control measures necessary. A variant ...
DOI:
10.1186/s12917-019-1979-5

7. Assessing antimicrobial misuse in small-scale chicken farms in Vietnam from an observational study

Author:
Choisy, Marc; Van Cuong, Nguyen; Bao, Truong Dinh; Kiet, Bach Tuan; Hien, Bo Ve; Thu, Ho Viet; Chansiripornchai, Niwat; Setyawan, Erry; Thwaites, Guy; Rushton, Jonathan; Carrique-Mas, Juan
Source:
BMC veterinary research 2019 v.15 no.1 pp. 206
ISSN:
1746-6148
Subject:
Eimeria; Protozoa; anti-infective agents; bacteria; chickens; chicks; disease control; expert opinion; farmers; farms; flocks; infectious diseases; models; observational studies; pathogens; probability; river deltas; signs and symptoms (animals and humans); slaughter; viruses; Vietnam
Abstract:
... BACKGROUND: Antimicrobials are used by poultry farmers in Vietnam as a tool to treat and prevent infectious diseases. We aimed to determine the fraction of disease episodes likely to remain untreated due to the administration of antimicrobials on non-susceptible pathogens in chicken flocks in the Mekong Delta of Vietnam. Weekly data on antimicrobial use and clinical signs were collected from 88 ra ...
DOI:
10.1186/s12917-019-1947-0

8. Autoimmune diseases affecting skin melanocytes in dogs, cats and horses: vitiligo and the uveodermatological syndrome: a comprehensive review

Author:
Tham, Heng L.; Linder, Keith E.; Olivry, Thierry
Source:
BMC veterinary research 2019 v.15 no.1 pp. 251
ISSN:
1746-6148
Subject:
animal diseases; autoimmune diseases; blindness; cats; dogs; histopathology; horses; humans; melanocytes; signs and symptoms (animals and humans); skin (animal); skin diseases; veterinary medicine
Abstract:
... Autoimmune dermatoses targeting melanocytes have gained attention in human medicine due to their progressive nature and the social impact suffered by affected individuals. In veterinary medicine, vitiligo and the uveodermatological syndrome are the two autoimmune diseases that are known to affect skin melanocytes.In the first part of this article, we will review the signalment, clinical signs, his ...
DOI:
10.1186/s12917-019-2003-9

9. A Vavraia-like microsporidium as the cause of deadly infection in threatened and endangered Eurycea salamanders in the United States

Author:
Yu, Xue; Hoyle, Rachel L.; Guo, Fengguang; Ratliff, Cameron M.; Cantu, Valentin; Crow, Justin; Xiang, Lixin; Heatley, J. Jill; Zhu, Guan
Source:
Parasites & vectors 2019 v.12 no.1 pp. 108
ISSN:
1756-3305
Subject:
Crustacea; Vavraia; aquatic invertebrates; behavior change; breeding programs; erythema; genes; gills; habitats; histopathology; humans; insects; microsporidiosis; monitoring; mortality; parasites; pathogens; phylogeny; polymerase chain reaction; rhabdomyolysis; ribosomal DNA; ribosomal RNA; salamanders and newts; secondary infection; signs and symptoms (animals and humans); snails; surveys; tail; threatened species; Texas
Abstract:
... BACKGROUND: Eurycea sosorum (Barton Springs salamander) and Eurycea nana (San Macros salamander) are listed as endangered and threatened species, respectively, by the U.S. Fish and Wildlife Service (USFWS) with habitats restricted to small regions near Austin, Texas, USA. The conservation efforts with the Eurycea salamanders at the captive breeding program in San Marcos Aquatic Resources Center (S ...
DOI:
10.1186/s13071-019-3369-z

10. Bovine respiratory syncytial virus in experimentally exposed and rechallenged calves; viral shedding related to clinical signs and the potential for transmission

Author:
Klem, Thea Blystad; Sjurseth, Siri Kulberg; Sviland, Ståle; Gjerset, Britt; Myrmel, Mette; Stokstad, Maria
Source:
BMC veterinary research 2019 v.15 no.1 pp. 156
ISSN:
1746-6148
Subject:
Bovine orthopneumovirus; RNA; animal welfare; calves; cell culture; clinical examination; enzyme-linked immunosorbent assay; nose; pathogens; respiratory tract diseases; serology; seroprevalence; signs and symptoms (animals and humans); viral shedding; virion; viruses
Abstract:
... BACKGROUND: Bovine respiratory syncytial virus (BRSV) is an important respiratory pathogen worldwide, detrimentally affecting the economy and animal welfare. To prevent and control BRSV infection, further knowledge on virus shedding and transmission potential in individual animals is required. This study aimed to detect viral RNA and infective virions during BRSV infection to evaluate duration of ...
DOI:
10.1186/s12917-019-1911-z

11. Cervical vertebral malformations in 9 dogs: radiological findings, treatment options and outcomes

Author:
Fernandes, Ricardo; Fitzpatrick, Noel; Rusbridge, Clare; Rose, Jeremy; Driver, Colin J.
Source:
Irish veterinary journal 2019 v.72 no.1 pp. 2
ISSN:
2046-0481
Subject:
abnormal development; cervical spine; cervical spondylomyelopathy; dogs; hospitals; humans; patients; prospective studies; scoliosis; signs and symptoms (animals and humans); surgery; vertebrae; veterinary medicine
Abstract:
... BACKGROUND: Disregarding atlantoaxial instability in toy breed dogs associated with dens malformation and cervical spondylomyelopathy; cervical vertebral malformations are rare and poorly characterised in veterinary medicine and consequently treatment strategies and clinical outcome are sparsely documented. RESULTS: Electronic clinical records at our veterinary referral hospital between April 2009 ...
DOI:
10.1186/s13620-019-0141-9

12. Changes in pre- and postoperative serum leptin concentrations in dogs with gallbladder mucocele and cholelithiasis

Author:
Lee, Sungin; Lee, Aeri; Kweon, Oh-kyeong; Kim, Wan Hee
Source:
BMC veterinary research 2019 v.15 no.1 pp. 215
ISSN:
1746-6148
Subject:
bilirubin; biomarkers; blood serum; cholelithiasis; cholesterol; death; dogs; enzymes; gall bladder; leptin; lipid composition; liver; prognosis; signs and symptoms (animals and humans); surgery; triacylglycerols
Abstract:
... BACKGROUND: Leptin has been shown to have various physiological and pathological roles in the canine gallbladder. In this study, we performed pre- and postoperative short-term follow-up analyses to confirm changes in serum leptin levels before and after cholecystectomy due to gallbladder mucocele (GBM) or cholelithiasis in dogs. RESULTS: Twenty-six cholecystectomized dogs (GBM: n = 14; cholelithia ...
DOI:
10.1186/s12917-019-1964-z

13. Characterization and protective efficacy of a Salmonella pathogenicity island 2 (SPI2) mutant of Salmonella Paratyphi A

Author:
Yin, Junlei; Cheng, Zhao; Wu, Yuchen; He, Qunli; Zhang, Jingjing; Yang, Zhanfeng; Ding, Shuming; Li, Jizong; Guo, Dongguang
Source:
Microbial pathogenesis 2019 v.137 pp. 103795
ISSN:
0882-4010
Subject:
Salmonella Paratyphi A; body weight; cell-mediated immunity; fever; live vaccines; liver; mice; mortality; mutants; paratyphoid; pathogenicity islands; signs and symptoms (animals and humans); spleen; vaccination; virulence
Abstract:
... Paratyphoid fever caused by Salmonella Paratyphi A is a serious public health problem in many countries. In order to and develop a live attenuated candidate vaccine of Salmonella Paratyphi A, a Salmonella pathogenicity island 2 (SPI2, approximate 40 kb) deletion mutant of Salmonella Paratyphi A was constructed by lambda Red recombination, then the biological characteristics and protective ability ...
DOI:
10.1016/j.micpath.2019.103795

14. Chronic intramammary infection by Listeria monocytogenes in a clinically healthy goat – a case report

Author:
Addis, Maria Filippa; Cubeddu, Tiziana; Pilicchi, Ylenia; Rocca, Stefano; Piccinini, Renata
Source:
BMC veterinary research 2019 v.15 no.1 pp. 229
ISSN:
1746-6148
Subject:
Gram-positive bacteria; Listeria monocytogenes; animal tissues; atrophy; bacterial culture; bulk milk; carrier state; case studies; dairy farming; dairy herds; diarrhea; encephalitis; epithelial cells; feces; fluorescent antibody technique; foodborne illness; fresh cheeses; goat milk; goats; humans; immunohistochemistry; lactation; listeriosis; macrophages; mammary glands; mastitis; milk; milk contamination; monitoring; neutrophils; septicemia; signs and symptoms (animals and humans); veterinary medicine
Abstract:
... BACKGROUND: Listeria monocytogenes is a ubiquitous Gram-positive bacterium responsible for a severe foodborne disease in humans, and contaminated dairy products can be an important source of infection. Typically, infected dairy ruminants show clinical manifestations including encephalitis, septicemia, abortion, and diarrhea, but may also become asymptomatic carriers and shed L. monocytogenes in th ...
DOI:
10.1186/s12917-019-1989-3

15. Clinical, laboratory and ultrasonographic findings in 87 cows with type-4 abomasal ulcer

Author:
Braun, Ueli; Reif, Christina; Nuss, Karl; Hilbe, Monika; Gerspach, Christian
Source:
BMC veterinary research 2019 v.15 no.1 pp. 100
ISSN:
1746-6148
Subject:
acidosis; anorexia; blood proteins; cows; euthanasia; feces; fever; health status; hematocrit; hematuria; hypoproteinemia; leukopenia; necropsy; peritonitis; rumen fluids; signs and symptoms (animals and humans); surface temperature; tachycardia; ultrasonography; veterinary medicine
Abstract:
... BACKGROUND: This study evaluated the clinical, laboratory, ultrasonographic and pathological findings in 87 cows aged 2 to 10 years (4.5 ± 1.5 years) with type-4 abomasal ulcer. RESULTS: The most common clinical findings were in decreasing order compromised health status accompanied by partial or complete anorexia (100%), abdominal guarding (81%), congested scleral vessels (77%), ruminal atony (73 ...
DOI:
10.1186/s12917-019-1844-6

16. Detection and characterization of a novel marine birnavirus isolated from Asian seabass in Singapore

Author:
Chen, Jing; Toh, Xinyu; Ong, Jasmine; Wang, Yahui; Teo, Xuan-Hui; Lee, Bernett; Wong, Pui-San; Khor, Denyse; Chong, Shin-Min; Chee, Diana; Wee, Alvin; Wang, Yifan; Ng, Mee-Keun; Tan, Boon-Huan; Huangfu, Taoqi
Source:
Virology journal 2019 v.16 no.1 pp. 71
ISSN:
1743-422X
Subject:
Aquabirnavirus; Lates calcarifer; Lepomis macrochirus; cell death; cell lines; chloroform; cytopathogenicity; disease outbreaks; disease transmission; economic impact; farmed animal species; fish; fish farms; genome; high-throughput nucleotide sequencing; monitoring; nucleotide sequences; phylogeny; polymerase chain reaction; signs and symptoms (animals and humans); transmission electron microscopy; viruses; Australia; Singapore
Abstract:
... BACKGROUND: Lates calcarifer, known as seabass in Asia and barramundi in Australia, is a widely farmed species internationally and in Southeast Asia and any disease outbreak will have a great economic impact on the aquaculture industry. Through disease investigation of Asian seabass from a coastal fish farm in 2015 in Singapore, a novel birnavirus named Lates calcarifer Birnavirus (LCBV) was detec ...
DOI:
10.1186/s12985-019-1174-0

17. Development of a recombinant Newcastle disease virus-vectored vaccine for infectious bronchitis virus variant strains circulating in Egypt

Author:
Abozeid, Hassanein H.; Paldurai, Anandan; Varghese, Berin P.; Khattar, Sunil K.; Afifi, Manal A.; Zouelfakkar, Sahar; El-Deeb, Ayman H.; El-Kady, Magdy F.; Samal, Siba K.
Source:
Veterinary research 2019 v.50 no.1 pp. 12
ISSN:
1297-9716
Subject:
Newcastle disease; protein synthesis; glycoproteins; live vaccines; infectious bronchitis; Western blotting; White Leghorn; Avian orthoavulavirus 1; viruses; Infectious bronchitis virus; viral shedding; vaccination; chicks; virulence; fluorescent antibody technique; signs and symptoms (animals and humans); poultry industry; Egypt; Middle East
Abstract:
... Infectious bronchitis virus (IBV) causes a major disease problem for the poultry industry worldwide. The currently used live-attenuated vaccines have the tendency to mutate and/or recombine with circulating field strains resulting in the emergence of vaccine-derived variant viruses. In order to circumvent these issues, and to develop a vaccine that is more relevant to Egypt and its neighboring cou ...
DOI:
10.1186/s13567-019-0631-5

18. Development of oligonucleotide microarray for accurate and simultaneous detection of avian respiratory viral diseases

Author:
Xiao, Qian; Yan, Liping; Yao, Lu; Lei, Jing; Bi, Zhenwei; Hu, Jianhua; Chen, Yuqing; Fang, An; Li, Hui; Li, Yuan; Yan, Yan; Zhou, Jiyong
Source:
BMC veterinary research 2019 v.15 no.1 pp. 253
ISSN:
1746-6148
Subject:
Avian orthoavulavirus 1; DNA microarrays; Infectious bronchitis virus; Infectious bursal disease virus; Influenza A virus; birds; cross reaction; detection limit; eggs; financial economics; humans; monitoring; pathogens; poultry industry; public health; rapid methods; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); viruses
Abstract:
... BACKGROUND: Avian influenza virus (AIV), infectious bronchitis virus (IBV), and Newcastle disease virus (NDV) are important avian pathogens that can cause enormous economic loss on the poultry industry. Different respiratory etiological agents may induce similar clinical signs that make differential diagnosis difficult. Importantly, AIV brings about severe threat to human public health. Therefore, ...
DOI:
10.1186/s12917-019-1985-7

19. Diet and nutrition: An important risk factor in leprosy

Author:
Dwivedi, Ved Prakash; Banerjee, Arindam; Das, Indraneel; Saha, Aparajita; Dutta, Malabika; Bhardwaj, Bhavya; Biswas, Saptarshi; Chattopadhyay, Debprasad
Source:
Microbial pathogenesis 2019 v.137 pp. 103714
ISSN:
0882-4010
Subject:
Mycobacterium leprae; World Health Organization; antibiotics; diet; humoral immunity; immune response; malnutrition; multibacillary leprosy; patients; risk factors; rural areas; signs and symptoms (animals and humans); therapeutics
Abstract:
... Leprosy, once considered as poor man's disease may cause severe neurological complications and physical disabilities. Classification of leprosy depends upon the cell mediated and humoral immune responses of the host, from tuberculoid to lepromatous stage. Current therapy to prevent the disease is not only very lengthy but also consists of expensive multiple antibiotics in combination. Treatment an ...
DOI:
10.1016/j.micpath.2019.103714

20. Ducks induce rapid and robust antibody responses than chickens at early time after intravenous infection with H9N2 avian influenza virus

Author:
Yang, Jianmei; Cui, Hongrui; Teng, Qiaoyang; Ma, Wenjun; Li, Xuesong; Wang, Binbin; Yan, Dawei; Chen, Hongjun; Liu, Qinfang; Li, Zejun
Source:
Virology journal 2019 v.16 no.1 pp. 46
ISSN:
1743-422X
Subject:
Influenza A virus; antibodies; chickens; ducks; humoral immunity; immune response; influenza; intravenous injection; signs and symptoms (animals and humans); tissues; virus replication; viruses; China
Abstract:
... BACKGROUND: Compared with chickens, ducks are normally resistant to avian influenza virus without clinical signs while they habor almost all subtypes of influenza A viruses. To date, however the mechanism for duck anti-influenza has not been completely understood. The H9N2 avian influenza virus (AIV) is the most prevalent subtype of influenza A virus that infects chickens and ducks in China. Howev ...
DOI:
10.1186/s12985-019-1150-8

21. Effectiveness of the spot-on combination of moxidectin and imidacloprid (Advocate®) in the treatment of ocular thelaziosis by Thelazia callipaeda in naturally infected cats

Author:
Otranto, Domenico; Solari Basano, Fabrizio; Pombi, Marco; Capelli, Gioia; Nazzari, Roberto; Falsone, Luigi; Petry, Gabriele; Pollmeier, Matthias Günter; Lia, Riccardo Paolo
Source:
Parasites & vectors 2019 v.12 no.1 pp. 25
ISSN:
1756-3305
Subject:
Thelazia callipaeda; adults; breeds; cat diseases; cats; conjunctivitis; enzootic diseases; eyes; females; imidacloprid; larvae; males; moxidectin; signs and symptoms (animals and humans); thelaziasis; therapeutics; Italy
Abstract:
... BACKGROUND: The present study evaluated the therapeutic effectiveness of moxidectin 1.0% (w/v) and imidacloprid 10% (w/v) (Advocate® spot-on solution for cats, Bayer Animal Health) against natural infections with the eyeworm Thelazia callipaeda in cats. This study was conducted as a GCP, negative-controlled, blinded and randomised field study in privately owned cats living in an area in southern I ...
DOI:
10.1186/s13071-018-3262-1

22. Effect of Pimobendan on NT-proBNP and c troponin I before and after a submaximal exercise test in dogs with preclinical mitral valve disease without cardiomegaly – a randomised, double-blinded trial

Author:
Iwanuk, Nayeli; Nolte, Ingo; Wall, Leona; Sehn, Maximiliane; Raue, Jonathan; Pilgram, Anna; Rumstedt, Katja; Bach, Jan-Peter
Source:
BMC veterinary research 2019 v.15 no.1 pp. 237
ISSN:
1746-6148
Subject:
biomarkers; dogs; echocardiography; exercise; exercise test; experimental design; heart valve diseases; leishmaniasis; monitoring; patients; signs and symptoms (animals and humans); troponin I
Abstract:
... BACKGROUND: Exercise testing in conjunction with measurement of cardiac biomarkers NT-proBNP and cTnI is a useful tool for monitoring the effect of treatment on cardiac patients. Administering Pimobendan in dogs with degenerative mitral valve disease (DMVD) and cardiomegaly results in delaying the onset of clinical symptoms and prolonging life. Its effect in dogs with DMVD without cardiomegaly has ...
DOI:
10.1186/s12917-019-1980-z

23. Effects of cyanobacterial toxins on the human gastrointestinal tract and the mucosal innate immune system

Author:
Kubickova, Barbara; Babica, Pavel; Hilscherová, Klára; Šindlerová, Lenka
Source:
Environmental sciences Europe 2019 v.31 no.1 pp. 31
ISSN:
2190-4707
Subject:
carcinogenicity; chronic exposure; cylindrospermopsin; drinking water; environmental health; epidemiological studies; freshwater ecosystems; gastrointestinal neoplasms; gastrointestinal system; immune system; in vivo studies; inflammation; ingestion; innate immunity; lipopolysaccharides; metabolites; microcystins; models; neurotoxicity; recreation; signs and symptoms (animals and humans); tissues; water pollution; water supply
Abstract:
... BACKGROUND: Cyanobacterial blooms occur with increasing frequency in freshwater ecosystems, posing a hazard to human and environmental health. Exposure of human to cyanobacterial metabolites occurs mostly via accidental ingestion through contaminated drinking water or during recreational activities and, most frequently, results in gastrointestinal symptoms. Despite the clinical manifestation, cyan ...
DOI:
10.1186/s12302-019-0212-2

24. Efficacy of oral fluralaner for the treatment of canine generalized demodicosis: a molecular-level confirmation

Author:
Djuric, Milos; Milcic Matic, Natalija; Davitkov, Darko; Glavinic, Uros; Davitkov, Dajana; Vejnovic, Branislav; Stanimirovic, Zoran
Source:
Parasites & vectors 2019 v.12 no.1 pp. 270
ISSN:
1756-3305
Subject:
DNA; Demodex canis; Siphonaptera; body weight; demodicosis; dogs; mites; oral administration; quantitative polymerase chain reaction; regrowth; signs and symptoms (animals and humans); ticks; veterinary medicine
Abstract:
... BACKGROUND: Canine generalized demodicosis is a common parasitic disease caused by the proliferation of Demodex mites. The introduction of isoxazoline class treatments in veterinary dermatology has resulted in apparently effective treatment of generalized demodicosis. The objective of this study was to evaluate the effectiveness of fluralaner for the treatment of canine generalized demodicosis usi ...
DOI:
10.1186/s13071-019-3521-9

25. Equine trypanosomosis: enigmas and diagnostic challenges

Author:
Büscher, Philippe; Gonzatti, Mary Isabel; Hébert, Laurent; Inoue, Noboru; Pascucci, Ilaria; Schnaufer, Achim; Suganuma, Keisuke; Touratier, Louis; Van Reet, Nick
Source:
Parasites & vectors 2019 v.12 no.1 pp. 234
ISSN:
1756-3305
Subject:
Glossina; Trypanosoma brucei; Trypanosoma congolense; Trypanosoma equiperdum; Trypanosoma evansi; Trypanosoma vivax; algorithms; bovine trypanosomiasis; diagnostic techniques; dourine; hematophagous insects; horses; immunologic techniques; infectious diseases; point-of-care systems; risk; signs and symptoms (animals and humans); surra; vaccines; Europe
Abstract:
... Equine trypanosomosis is a complex of infectious diseases called dourine, nagana and surra. It is caused by several species of the genus Trypanosoma that are transmitted cyclically by tsetse flies, mechanically by other haematophagous flies, or sexually. Trypanosoma congolense (subgenus Nannomonas) and T. vivax (subgenus Dutonella) are genetically and morphologically distinct from T. brucei, T. eq ...
DOI:
10.1186/s13071-019-3484-x

26. Evaluation of a dry therapeutic urinary diet and concurrent administration of antimicrobials for struvite cystolith dissolution in dogs

Author:
Dear, Jonathan D.; Larsen, Jennifer A.; Bannasch, Michael; Hulsebosch, Sean E.; Gagne, Jason W.; Johnson, Eric G.; Westropp, Jodi L.
Source:
BMC veterinary research 2019 v.15 no.1 pp. 273
ISSN:
1746-6148
Subject:
anti-infective agents; bladder calculi; calcium phosphates; compliance; diet; dog feeding; dogs; drug therapy; magnesium ammonium phosphate; pH; radiography; signs and symptoms (animals and humans); urinary tract
Abstract:
... BACKGROUND: Struvite urolithiasis with bacterial urinary tract infection (UTI) is commonly reported in dogs; few data exist to describe successful dissolution protocols in dogs with naturally occurring disease. We hypothesized that a dry therapeutic urinary diet combined with targeted antimicrobial therapy can effectively dissolve presumptive struvite cystolithiasis in dogs with naturally occurrin ...
DOI:
10.1186/s12917-019-1992-8

27. Evaluation of transmission potential and pathobiological characteristics of mallard originated Avian orthoavulavirus 1 (sub-genotype VII.2) in commercial broilers

Author:
Habib, Momena; Yaqub, Tahir; Aziz-ul-Rahman,; Sohail, Tayyebah; Shahbaz, Muhammad; Shehzad, Wasim; Munir, Muhammad; Shabbir, Muhammad Zubair
Source:
Microbial pathogenesis 2019 v.137 pp. 103785
ISSN:
0882-4010
Subject:
Anas platyrhynchos; Avian orthoavulavirus 1; Newcastle disease; RNA; cecum; chickens; diarrhea; disease outbreaks; disease surveillance; genes; genomics; hemorrhage; migratory behavior; migratory birds; monitoring; mortality; necropsy; phylogeny; proventriculus; signs and symptoms (animals and humans); subgenotype; tissue tropism; tonsils; vaccination; viruses; waterfowl
Abstract:
... Newcastle disease (ND), caused by Avian orthoavulavirus 1 (AOAV-1), affects multiple avian species around the globe. Frequent disease outbreaks are not uncommon even in vaccinates despite routine vaccination and, in this regards, viruses of diverse genotypes originating from natural reservoirs (migratory waterfowls) play an important role in a disease endemic setting. Though genomic characterizati ...
DOI:
10.1016/j.micpath.2019.103785

28. Experimental infection of Korean native goats (Capra aegagrus hircus) with bovine viral diarrhea virus 1b

Author:
Oem, Jae-Ku; Han, Du-Gyeong; Choi, Kyoung-Seong
Source:
BMC veterinary research 2019 v.15 no.1 pp. 202
ISSN:
1746-6148
Subject:
nose; sequence analysis; Capra hircus aegarus; monitoring; blood sampling; antibodies; cattle; goats; proteinases; reverse transcriptase polymerase chain reaction; veterinary medicine; enzyme-linked immunosorbent assay; viruses; Bovine viral diarrhea virus 1; nucleotide sequences; goat diseases; RNA; blood; signs and symptoms (animals and humans); South Korea
Abstract:
... BACKGROUND: Bovine viral diarrhea virus (BVDV) infects various ungulates and causes reproductive failure in infected goats. BVDV has been detected among goats in the Republic of Korea, but the route of transmission remains unclear. Here, we aimed to investigate whether BVDV-1b circulating among Korean cattle can be transmitted to Korean native goats (Capra aegagrus hircus) and characterize the out ...
DOI:
10.1186/s12917-019-1955-0

29. Expression profile analysis of 5-day-old neonatal piglets infected with porcine Deltacoronavirus

Author:
Wu, Jiao L.; Mai, Kai J.; Li, Di; Wu, Rui T.; Wu, Zi X.; Tang, Xiao Y.; Li, Qian N.; Sun, Yuan; Lan, Tian; Zhang, Xiang B.; Ma, Jing Y.
Source:
BMC veterinary research 2019 v.15 no.1 pp. 117
ISSN:
1746-6148
Subject:
Deltacoronavirus; appetite; biochemical pathways; death; diarrhea; digestion; emaciation; endoplasmic reticulum; fatty acid metabolism; fatty acid-binding proteins; fatty acids; gene expression regulation; genes; histopathology; immunohistochemistry; messenger RNA; microarray technology; mitochondria; pathogenesis; peroxisome proliferator-activated receptors; physiological transport; piglets; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction; signs and symptoms (animals and humans); staining; veterinary medicine; viral growth; weight loss
Abstract:
... BACKGROUND: Porcine deltacoronavirus (PDCoV) is a novel coronavirus that can cause diarrhea in nursing piglets. This study was aimed to investigate the roles of host differentially expressed genes on metabolic pathways in PDCoV infections. RESULTS: Twenty thousand six hundred seventy-four differentially expressed mRNAs were identified in 5-day-old piglets responded to PDCoV experimental infections ...
DOI:
10.1186/s12917-019-1848-2

30. Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle

Author:
Orono, Sheillah Ayiela; Gitao, George Chege; Mpatswenumugabo, Jean Pierre; Chepkwony, Maurine; Mutisya, Christine; Okoth, Edward; Bronsvoort, Barend Mark de Clare; Russell, George Cameron; Nene, Vishvanath; Cook, Elizabeth Anne Jessie
Source:
BMC veterinary research 2019 v.15 no.1 pp. 69
ISSN:
1746-6148
Subject:
calving; cattle; disease control; enzyme-linked immunosorbent assay; financial economics; herds; laboratory diagnosis; malignant catarrhal fever; models; polymerase chain reaction; retrospective studies; signs and symptoms (animals and humans); wildebeest; Kenya
Abstract:
... BACKGROUND: Wildebeest associated malignant catarrhal fever (WA-MCF) is a fatal disease of cattle. Outbreaks are seasonal and associated with close interaction between cattle and calving wildebeest. In Kenya, WA-MCF has a dramatic effect on cattle-keepers who lose up to 10% of their cattle herds per year. The objective of this study was to report the impact of WA-MCF on a commercial ranch and asse ...
DOI:
10.1186/s12917-019-1818-8

31. First report of pulmonary cysticercosis caused by Taenia crassiceps in a Cape fur seal (Arctocephalus pusillus)

Author:
Delling, Cora; Böttcher, Denny; Schiffbauer, Vivien; Bernhard, Andreas; Schmäschke, Ronald
Source:
International journal for parasitology 2019 v.10 pp. 83-86
ISSN:
2213-2244
Subject:
Arctocephalus pusillus pusillus; Taenia crassiceps; Vulpes vulpes; carnivores; cysticercosis; dogs; females; foxes; intestines; larvae; lungs; muscles; parasitism; pets; protoscoleces; rodents; signs and symptoms (animals and humans); wild animals; zoonoses; zoos
Abstract:
... The cestode Taenia crassiceps parasitizes in the intestine of domestic and wild carnivores, especially in red foxes. Usually, the metacestode stage, also known as Cysticercus longicollis, is located in muscles, peritoneal and pleural cavity of wild rodents. In this case, larval stages were found in a female Cape fur seal, which lived in a German zoo since June 1998. In January 2019, the animal pre ...
DOI:
10.1016/j.ijppaw.2019.07.006

32. Gastrointestinal parasites in shelter cats of central Italy

Author:
Sauda, Federica; Malandrucco, Livia; De Liberato, Claudio; Perrucci, Stefania
Source:
Veterinary Parasitology: Regional Studies and Reports 2019 v.18 pp. 100321
ISSN:
2405-9390
Subject:
Cryptosporidium; Giardia lamblia; Strongyloides; Toxocara cati; Tritrichomonas foetus; animal rescue shelters; bivariate analysis; cats; control methods; feces; gastrointestinal parasites; helminthiasis; hookworms; host specificity; mixed infection; protozoal infections; regression analysis; risk factors; signs and symptoms (animals and humans); zoonoses; Italy
Abstract:
... In Italy, the limited resources and the large number of cats living in feline shelters may facilitate the spread of parasite infections that may affect the health of cats and expose shelter workers and adoptive owners to zoonosis. Prevalence and risk factors of potential zoonotic and host­specific gastrointestinal parasite infections were assessed in cats living in public and private shelters of c ...
DOI:
10.1016/j.vprsr.2019.100321

33. Growth characteristics of the novel goose parvovirus SD15 strain in vitro

Author:
Zhang, Jinyue; Liu, Peng; Wu, Yuanyuan; Wang, Mingshu; Jia, Renyong; Zhu, Dekang; Liu, Mafeng; Yang, Qiao; Wu, Ying; Zhao, Xinxin; Zhang, Shaqiu; Liu, Yunya; Zhang, Ling; Yu, Yanling; You, Yu; Chen, Shun; Cheng, Anchun
Source:
BMC veterinary research 2019 v.15 no.1 pp. 63
ISSN:
1746-6148
Subject:
Anseriform dependoparvovirus 1; allantoic fluid; apoptosis; beak; cytotoxicity; ducks; dwarfing; eggs; fibroblasts; financial economics; fluorescent antibody technique; geese; harvesting; intestines; liver; poultry feeding; quantitative polymerase chain reaction; signs and symptoms (animals and humans); tongue; vaccines; viral load; viruses; China
Abstract:
... BACKGROUND: Short beak and dwarfism syndrome (SBDS) was caused by novel goose parvovirus (NGPV)--a variant of goose parvovirus (GPV). Ducks infected with NGPV shows clinical signs including growth retardation and protrusion of the tongue from an atrophied beak. SBDS outbreak was first reported at the northern coastal provinces of China during 2015 and it was again reported in Sichuan, an inland pr ...
DOI:
10.1186/s12917-019-1807-y

34. Histopathological lesions in reproductive organs, distal spinal cord and peripheral nerves of horses naturally infected with Trypanosoma equiperdum

Author:
Yasine, Ahmed; Ashenafi, Hagos; Geldhof, Peter; Van Brantegem, Leen; Vercauteren, Griet; Bekana, Merga; Tola, Alemu; Van Soom, Ann; Duchateau, Luc; Goddeeris, Bruno; Govaere, Jan
Source:
BMC veterinary research 2019 v.15 no.1 pp. 175
ISSN:
1746-6148
Subject:
Trypanosoma equiperdum; Trypanosoma evansi; ataxia (disorder); dourine; ganglia; genitalia; hematocrit; histopathology; horses; internal transcribed spacers; legs; necropsy; nerve tissue; peripheral nerves; quantitative polymerase chain reaction; seminiferous tubules; signs and symptoms (animals and humans); spinal cord; uterus; vagina
Abstract:
... BACKGROUND: Dourine, a venereal transmitted trypanosomosis caused by Trypanosoma equiperdum, has different clinical signs related to the reproductive and nervous system. Pathologic tissue changes associated with the disease are poorly described. The present study describes the histopathological lesions in naturally T. equiperdum-infected horses in the chronical stage of dourine. RESULTS: Four chro ...
DOI:
10.1186/s12917-019-1916-7

35. H3N2 canine influenza virus and Enterococcus faecalis coinfection in dogs in China

Author:
Zhou, Liwei; Sun, Haoran; Song, Shikai; Liu, Jinhua; Xia, Zhaofei; Sun, Yipeng; Lyu, Yanli
Source:
BMC veterinary research 2019 v.15 no.1 pp. 113
ISSN:
1746-6148
Subject:
Enterococcus faecalis; German Shepherd; Influenza A virus; Oriental traditional medicine; antibiotic resistance; azithromycin; bacteria; bacterial culture; breeding; dogs; enrofloxacin; genes; hematology; hospitals; inflammation; intravenous injection; mixed infection; nose; pneumonia; quantitative polymerase chain reaction; radiography; ribosomal RNA; secondary infection; signs and symptoms (animals and humans); China
Abstract:
... BACKGROUND: In May 2017, 17 dogs in a German Shepherd breeding kennel in northern China developed respiratory clinical signs. The owner treated the dogs with an intravenous injection of Shuang-Huang-lian, a traditional Chinese medicine, and azithromycin. The respiratory signs improved 3 days post-treatment, however, cysts were observed in the necks of eight dogs, and three of them died in the foll ...
DOI:
10.1186/s12917-019-1832-x

36. Identification of novel drug targets for humans and potential vaccine targets for cattle by subtractive genomic analysis of Brucella abortus strain 2308

Author:
Mahmud, Araf; Khan, Md. Tahsin; Iqbal, Asif
Source:
Microbial pathogenesis 2019 v.137 pp. 103731
ISSN:
0882-4010
Subject:
ABC transporters; Brucella melitensis biovar Abortus; acriflavine; antibiotic resistance; antibiotics; arthritis; biochemical pathways; bioinformatics; breast feeding; brucellosis; cows; developing countries; direct contact; disease transmission; enzymes; fever; financial economics; genomics; hosts; humans; income; milk production; pathogens; placenta; proteome; signs and symptoms (animals and humans); therapeutics; tissues; vaccines; zoonoses
Abstract:
... Brucella abortus is the causative agent of brucellosis, a neglected endemic zoonotic disease. It causes devastating economic losses in low income and developing countries. Clinical symptoms of infected cows include abortion, poor weight, reduced fertility gain and reduction in milk production. Transmission of the zoonotic disease from cattle to human can occur through direct contact with infected ...
DOI:
10.1016/j.micpath.2019.103731

37. Increased genetic variation of bovine viral diarrhea virus in dairy cattle in Poland

Author:
Mirosław, Paweł; Polak, Mirosław
Source:
BMC veterinary research 2019 v.15 no.1 pp. 278
ISSN:
1746-6148
Subject:
5' untranslated regions; Bovine viral diarrhea virus 1; dairy cattle; dairy herds; diagnostic techniques; financial economics; genetic variation; genome; genotype; pathogens; phylogeny; signs and symptoms (animals and humans); vaccines; viruses; Poland
Abstract:
... BACKGROUND: Bovine viral diarrhea virus (BVDV) causes severe economic losses and is one of the most important viral pathogens of ruminants worldwide. The infection manifests itself in a variety of clinical symptoms. Phylogenetic studies based mainly on 5’UTR of its genome, identified many different subtypes of BVDV. Previous study indicated the predominance of BVDV-1b and BVDV-1d in Poland. The ai ...
DOI:
10.1186/s12917-019-2029-z

38. Intracranial abscess formation in an adult alpaca: a case report

Author:
Franz, Sonja; Högler, Sandra; Gumpenberger, Michaela; Dadak, Agnes
Source:
BMC veterinary research 2019 v.15 no.1 pp. 183
ISSN:
1746-6148
Subject:
Camelidae; abscess; adults; alpacas; brain; case studies; computed tomography; deformation; ears; emaciation; females; nerve tissue; nervous system diseases; otitis; signs and symptoms (animals and humans); veterinary clinics
Abstract:
... BACKGROUND: Intracranial abscess formation is an extremely rare and sporadically documented disease in South American Camelids (SACs). Herein we report the first case of otogenic brain abscess formation in this species. CASE PRESENTATION: A 4 years old female alpaca was presented to our veterinary hospital with a 6 month history of neurologic disorder symptoms, mainly head tilt to the right and em ...
DOI:
10.1186/s12917-019-1930-9

39. Intravitreal injection of low-dose gentamicin for the treatment of recurrent or persistent uveitis in horses: Preliminary results.

Author:
Fischer, Britta M.; McMullen, Richard J., Jr; Reese, Sven; Brehm, Walter
Source:
BMC veterinary research 2019 v.15 no.1 pp. 29
ISSN:
1746-6148
Subject:
anesthesia; breeds; cataract; cyclosporine; eyes; gender; gentamicin; hemorrhage; horses; inflammation; intravitreal injection; prospective studies; retinal degeneration; sedation; signs and symptoms (animals and humans)
Abstract:
... BACKGROUND: Despite appropriate medical therapy, many horses with equine recurrent uveitis continue to suffer from recurrent bouts of inflammation. Surgical intervention via the pars plana vitrectomy or suprachoroidal cyclosporine implant placement may control and/or prevent recurrences, however, these procedures may be contraindicated, unavailable, or declined by an owner. Thus, an effective adju ...
DOI:
10.1186/s12917-018-1722-7

40. Knowledge and risk factors for foot-and-mouth disease among small-scale dairy farmers in an endemic setting

Author:
Nyaguthii, Dickson Machira; Armson, Bryony; Kitala, Philip Mwanzia; Sanz-Bernardo, Beatriz; Di Nardo, Antonello; Lyons, Nicholas Anthony
Source:
Veterinary research 2019 v.50 no.1 pp. 33
ISSN:
1297-9716
Subject:
animal diseases; bulls; cross-sectional studies; farm area; farmers; farms; foot-and-mouth disease; interviews; multivariate analysis; risk factors; risk reduction; sheep; signs and symptoms (animals and humans); small-scale farming; Kenya
Abstract:
... Foot-and-mouth disease (FMD) is a highly contagious viral infection of cloven-hoofed animals. In Kenya, the disease is endemic with outbreaks typically occurring throughout the year. A cross-sectional study was undertaken in Nakuru County to investigate farmer knowledge and risk factors for clinical disease. Semi-structured interviews were conducted on 220 smallholder farmers, selected using rando ...
DOI:
10.1186/s13567-019-0652-0

41. Lawsonia intracellularis associated equine proliferative enteropathy in Danish weanling foals

Author:
Bohlin, Anna Margareta; Olsen, Susanne Nautrup; Laursen, Sigrid Hyldahl; Öhman, Anna; van Galen, Gaby
Source:
Acta veterinaria scandinavica 2019 v.61 no.1 pp. 12
ISSN:
1751-0147
Subject:
Friesian (horse breed); arthritis; foals; fluorescence in situ hybridization; parasitism; diarrhea; weanlings; bacteria; Lawsonia intracellularis; Strongylus vulgaris; peroxidase; body condition; infarction; blood serum; ileum; hospitals; polymerase chain reaction; signs and symptoms (animals and humans); weaning; fluorescent antibody technique; hypoalbuminemia; intravenous injection; fever; Denmark
Abstract:
... BACKGROUND: Lawsonia intracellularis, an obligate intracellular bacterium, causes equine proliferative enteropathy, mainly in horses around weaning. This disease is rarely reported in the Scandinavian countries. RESULTS: Five cases of equine proliferative enteropathy were diagnosed between 2008–2016 at the University of Copenhagen Large Animal Teaching Hospital. Cases were Danish Warmbloods and a ...
DOI:
10.1186/s13028-019-0447-3

42. Longitudinal field studies reveal early infection and persistence of influenza A virus in piglets despite the presence of maternally derived antibodies

Author:
Ryt-Hansen, Pia; Larsen, Inge; Kristensen, Charlotte Sonne; Krog, Jesper Schak; Wacheck, Silke; Larsen, Lars Erik
Source:
Veterinary research 2019 v.50 no.1 pp. 36
ISSN:
1297-9716
Subject:
Influenza A virus; antibodies; blood; blood sampling; clinical examination; farrowing; herds; longitudinal studies; nose; piglets; respiratory tract diseases; signs and symptoms (animals and humans); sows; viruses
Abstract:
... A longitudinal study was performed in three Danish farrow to grower (30 kilos) herds over a 4-month period to investigate the dynamics and clinical impacts of influenza A virus (IAV) infections. In each herd, four batches consisting of four sows each with five ear-tagged piglets were included. Nasal swabs and/or blood were sampled from the sows and/or the piglets prior to farrowing and at weeks 1, ...
DOI:
10.1186/s13567-019-0655-x

43. Long-term computed tomography follow-up in great Danes with or without signs of osseous- associated cervical Spondylomyelopathy

Author:
Vansteenkiste, Daniella; Martin-Vaquero, Paula; Bonelli, Marília; da Costa, Luciana B.; da Costa, Ronaldo C.
Source:
BMC veterinary research 2019 v.15 no.1 pp. 90
ISSN:
1746-6148
Subject:
Great Dane; cervical spondylomyelopathy; computed tomography; dogs; morphometry; natural history; prospective studies; signs and symptoms (animals and humans)
Abstract:
... BACKGROUND: Osseous- associated cervical spondylomyelopathy (OA-CSM) has a high prevalence in Great Danes. In order to understand the progression of osseous changes, we aimed to perform a long-term computed tomographic (CT) follow-up study of Great Dane dogs with and without OA-CSM. Canine CSM is comparable to a common neurologic disease often diagnosed in older people termed cervical spondylotic ...
DOI:
10.1186/s12917-019-1835-7

44. Low concentration of serum immunoglobulin G is associated with pre-weaning diarrhea in young mink kits (Neovison vison)

Author:
Mathiesen, Ronja; Chriél, Mariann; Struve, Tina; Heegaard, Peter Mikael Helweg
Source:
Acta veterinaria scandinavica 2019 v.61 no.1 pp. 26
ISSN:
1751-0147
Subject:
Neovison vison; absorption; anti-infective agents; blood sampling; blood serum; breeding; diarrhea; etiology; farms; immunoglobulin G; intestinal absorption; lactation; maternal milk; mink; mink diseases; signs and symptoms (animals and humans); vaccine development; weight gain
Abstract:
... BACKGROUND: Pre-weaning diarrhea (PWD) is a severe syndrome, with world-wide occurrence, affecting farmed mink (Neovison vison) kits during the lactation period. Kits affected by PWD often display clinical signs such as: yellow-white diarrhea, greasy skin, and dehydration. In severe cases the kits eventually die. It is common practice to treat PWD using antimicrobials; however the effect is not we ...
DOI:
10.1186/s13028-019-0461-5

45. Magnetic resonance image findings in pug dogs with thoracolumbar myelopathy and concurrent caudal articular process dysplasia

Author:
Driver, Colin J.; Rose, Jeremy; Tauro, Anna; Fernandes, Ricardo; Rusbridge, Clare
Source:
BMC veterinary research 2019 v.15 no.1 pp. 182
ISSN:
1746-6148
Subject:
abnormal development; ataxia (disorder); body weight; castration; computed tomography; diverticulum; dog breeds; fibrosis; gender; intervertebral disks; magnetic resonance imaging; signs and symptoms (animals and humans); spinal cord; veterinary medicine
Abstract:
... BACKGROUND: A retrospective case series study was undertaken to describe the magnetic resonance imaging (MRI) findings in Pug dogs with thoracolumbar myelopathy and concurrent caudal articular process (CAP) dysplasia. Electronic clinical records were searched for Pug dogs who underwent MRI for the investigation of a T3-L3 spinal cord segment disease with subsequent confirmation of CAP dysplasia wi ...
DOI:
10.1186/s12917-019-1866-0

46. Molecular characterization of two novel reoviruses isolated from Muscovy ducklings in Guangdong, China

Author:
Zhang, Xue-Lian; Shao, Jian-Wei; Li, Xiao-Wen; Mei, Min-Min; Guo, Jin-Yue; Li, Wen-Feng; Huang, Wen-Jing; Chi, Shi-Hong; Yuan, Sheng; Li, Zhi-Li; Huang, Shu-Jian
Source:
BMC veterinary research 2019 v.15 no.1 pp. 143
ISSN:
1746-6148
Subject:
Cairina moschata; Muscovy; Reoviridae; conserved sequences; cytopathogenicity; ducklings; genome; genomics; morbidity; mortality; nucleotide sequences; phylogeny; sequence analysis; signs and symptoms (animals and humans); vaccines; viruses; waterfowl; China
Abstract:
... BACKGROUND: Novel Muscovy duck reovirus (N-MDRV), emerged in southeast China in 2002, which can infect a wide range of waterfowl and induces clinical signs and cytopathic effects that are distinct from those of classical MDRV, and continues to cause high morbidity and 5–50% mortality in ducklings. The present study aimed to investigate the characteristics of two novel reoviruses isolated from Musc ...
DOI:
10.1186/s12917-019-1877-x

47. Non-functional thyroid cystadenoma in three boxer dogs

Author:
Maurin, Marie-Pauline; Davies, Dan; Jahns, Hanne; Shiel, Robert E.; Mooney, Carmel T.
Source:
BMC veterinary research 2019 v.15 no.1 pp. 228
ISSN:
1746-6148
Subject:
Boxer (dog breed); adenoma; computed tomography; dogs; excision; histopathology; image analysis; mast cells; melanoma; signs and symptoms (animals and humans); thyroid gland; thyroid neoplasms; thyroxine; tissues; ultrasonography
Abstract:
... BACKGROUND: Thyroid neoplasia is a common endocrine neoplasm in dogs. The boxer is one of the reported breeds predisposed to malignant thyroid neoplasia. However, the association between thyroid neoplasia, malignancy and breed should be considered with caution. CASES PRESENTATION: This article describes the presentation, clinical pathological findings, computed tomographic (CT) imaging findings an ...
DOI:
10.1186/s12917-019-1948-z

48. Pathogenicity comparison of duck Tembusu virus in different aged Cherry Valley breeding ducks

Author:
Lv, Chuanwei; Li, Rong; Liu, Xingpo; Li, Ning; Liu, Sidang
Source:
BMC veterinary research 2019 v.15 no.1 pp. 282
ISSN:
1746-6148
Subject:
Tembusu virus; ataxia (disorder); blood serum; breeding; deformation; ducklings; feathers; heart; hemorrhage; hyperemia; immune response; interferon-gamma; interleukin-2; intramuscular injection; neutralizing antibodies; oviducts; oviposition; pathogenicity; signs and symptoms (animals and humans); splenomegaly; tissues; veterinary medicine; viral encephalitis; viral load; viruses
Abstract:
... BACKGROUND: Although several studies have revealed that the sensitivity of ducklings to duck Tembusu virus (DTMUV) was related to age, however, DTMUV was originally isolated from egg-laying ducks, and the ovary was the target organ of this virus. Cherry Valley breeding ducks aged 15- and 55-week-old (they are reserve breeding ducks and the normal egg-laying breeding ducks, respectively) were infec ...
DOI:
10.1186/s12917-019-2020-8

49. PCR and serology confirm the infection of turkey hens and their resilience to histomonosis in mixed flocks following high mortalities in toms

Author:
Sulejmanović, Tarik; Grafl, Beatrice; Bilić, Ivana; Jaskulska, Barbara; Hess, Michael
Source:
Parasites & vectors 2019 v.12 no.1 pp. 228
ISSN:
1756-3305
Subject:
Histomonas meleagridis; antibody detection; blood serum; cloaca; disease severity; dust; enzyme-linked immunosorbent assay; euthanasia; farms; flocks; hens; loci; mortality; necropsy; parasites; phylogeny; poultry diseases; quantitative polymerase chain reaction; ribosomal DNA; ribosomal RNA; sequence analysis; serology; signs and symptoms (animals and humans); toms; turkey hens
Abstract:
... BACKGROUND: Histomonosis, caused by the protozoan parasite Histomonas meleagridis, is a severe disease especially in turkeys where it can cause high mortalities. Recently, outbreaks were described in which turkey hens showed no clinical signs despite high mortalities in toms, from which they were separated only by a wire fence. The present study investigated three similar outbreaks of histomonosis ...
DOI:
10.1186/s13071-019-3482-z

50. Pilot study evaluating the efficacy of a topical formulation containing emodepside and praziquantel in the treatment of natural feline troglostrongylosis

Author:
Traversa, Donato; Veronesi, Fabrizia; Danesi, Patrizia; Morelli, Simone; Crisi, Paolo E.; Morganti, Giulia; Iorio, Raffaella; Pampurini, Fabrizio; Schaper, Roland; Santoro, Azzurra; Paoletti, Barbara; Di Cesare, Angela
Source:
Parasites & vectors 2019 v.12 no.1 pp. 97
ISSN:
1756-3305
Subject:
Aelurostrongylus; Felidae; arithmetics; cats; geometry; larvae; lungworms; praziquantel; signs and symptoms (animals and humans); Mediterranean region
Abstract:
... BACKGROUND: Troglostrongylus brevior, a lungworm usually affecting wild felids, has been recently recorded in a number of cases in domestic cats, mainly in Mediterranean areas. Although feline troglostrongylosis is a severe and life-threatening disease, especially in young cats, treatment options are very limited. The present study evaluated the efficacy and safety of a spot-on formulation contain ...
DOI:
10.1186/s13071-019-3361-7

51. Prevalence and diversity of avian blood parasites in a resident northern passerine

Author:
Van Hemert, Caroline; Meixell, Brandt W.; Smith, Matthew M.; Handel, Colleen M.
Source:
Parasites & vectors 2019 v.12 no.1 pp. 292
ISSN:
1756-3305
Subject:
Corvus; Haemoproteus; Leucocytozoon; Plasmodium; beak; body condition; climatic factors; crows; forest habitats; genetic variation; hemoparasites; host specificity; keratin; latitude; littoral zone; mixed infection; models; phylogeny; signs and symptoms (animals and humans); Alaska
Abstract:
... BACKGROUND: Climate-related changes are expected to influence the prevalence and distribution of vector-borne haemosporidian parasites at northern latitudes, although baseline information about resident birds is still lacking. In this study, we investigated prevalence and genetic diversity of Plasmodium, Haemoproteus, and Leucocytozoon parasites infecting the northwestern crow (Corvus caurinus), a ...
DOI:
10.1186/s13071-019-3545-1

52. Prevalence and genotypic identification of Cryptosporidium spp., Giardia duodenalis and Enterocytozoon bieneusi in pre-weaned dairy calves in Guangdong, China

Author:
Feng, Yuanyuan; Gong, Xiaoqing; Zhu, Kexin; Li, Na; Yu, Zhengjie; Guo, Yaqiong; Weng, Yabiao; Kváč, Martin; Feng, Yaoyu; Xiao, Lihua
Source:
Parasites & vectors 2019 v.12 no.1 pp. 41
ISSN:
1756-3305
Subject:
Cryptosporidium bovis; Cryptosporidium parvum; Cryptosporidium ryanae; Enterocytozoon bieneusi; Giardia lamblia; chi-square distribution; climate; dairy calves; disease transmission; dominant species; emerging diseases; enteropathogens; genotype; genotyping; humans; loci; monsoon season; polymerase chain reaction; sequence analysis; signs and symptoms (animals and humans); spring; summer; winter; zoonoses; China
Abstract:
... BACKGROUND: Cryptosporidium spp., Giardia duodenalis and Enterocytozoon bieneusi are common enteric pathogens in humans and animals. Data on the transmission of these pathogens are scarce from Guangdong, China, which has a subtropical monsoon climate and is the epicenter for many emerging infectious diseases. This study was conducted to better understand the prevalence and identity of the three pa ...
DOI:
10.1186/s13071-019-3310-5

53. Probiotic potential of Lactobacillus on the intestinal microflora against Escherichia coli induced mice model through high-throughput sequencing

Author:
Wang, Yaping; Li, Aoyun; Zhang, Lihong; Waqas, Muhammad; Mehmood, Khalid; Iqbal, Mudassar; Muyou, Can; Li, Zhixing; Lian, Yi; Sizhu, Suolang; Li, Jiakui
Source:
Microbial pathogenesis 2019 v.137 pp. 103760
ISSN:
0882-4010
Subject:
Bacteroidetes; Clostridium; Lactobacillus mucosae; Lactobacillus reuteri; Pseudomonas; Streptococcus; Vibrio; animal models; antibacterial properties; bile; body weight; cecum; diarrhea; duodenum; enteroinvasive Escherichia coli; heat; high-throughput nucleotide sequencing; ileum; in vitro studies; intestinal microorganisms; mice; pathogens; probiotics; signs and symptoms (animals and humans); yaks
Abstract:
... The aim of this study was to evaluate the antibacterial potential of Lactobacillus screened from Tibetan yaks on clinical symptoms and intestinal microflora in enteroinvasive Escherichia coli (EIEC) induced mice model. In vitro study, Lactobacillus reuteri (LR1) exhibited stronger resistance to acid and bile and inhibited the growth of EIEC than Lactobacillus mucosae (LM1). The mice were randomly ...
DOI:
10.1016/j.micpath.2019.103760

54. Pulmonary arterial response to Angiostrongylus vasorum in naturally infected dogs: echocardiographic findings in two cases

Author:
Corda, Andrea; Carta, Silvia; Varcasia, Antonio; Tamponi, Claudia; Evangelisti, Maria Antonietta; Scala, Antonio; Pinna Parpaglia, Maria Luisa
Source:
Parasites & vectors 2019 v.12 no.1 pp. 286
ISSN:
1756-3305
Subject:
Angiostrongylus vasorum; Canidae; dog diseases; dogs; echocardiography; heart failure; hypertension; pulmonary artery; respiratory tract diseases; signs and symptoms (animals and humans)
Abstract:
... BACKGROUND: Angiostrongylus vasorum is a nematode living in the pulmonary arteries of canids. Infected dogs develop severe pulmonary lesions which can potentially lead to pulmonary hypertension (PH). However, reports of PH in natural infected dogs are scant. One of the possible causes of the low prevalence of PH in A. vasorum-infected dogs could be the establishment of large diameter intrapulmonar ...
DOI:
10.1186/s13071-019-3544-2

55. Purification of recombinant IpaJ to develop an indirect ELISA-based method for detecting Salmonella enterica serovar Pullorum infections in chickens

Author:
Li, Qiuchun; Zhu, Yue; Yin, Kequan; Xu, Lijuan; Yin, Chao; Li, Yang; Ren, Jingwei; Yuan, Yu; Jiao, Xinan
Source:
BMC veterinary research 2019 v.15 no.1 pp. 3
ISSN:
1746-6148
Subject:
Escherichia coli; Salmonella Pullorum; acute course; adults; agglutination tests; antibodies; antigens; antiserum; chickens; chicks; enzyme-linked immunosorbent assay; farms; infectious diseases; morbidity; mortality; pathogens; poultry industry; pullorum disease; recombinant fusion proteins; serotypes; signs and symptoms (animals and humans)
Abstract:
... BACKGROUND: Salmonella enterica serovar Pullorum is a host-restricted serotype causing infection in poultry. The pathogen can not only cause acute infection in young chicks with high mortality and morbidity, but also persist in adult chickens without evident clinical symptoms and lead to vertical transmission. To eradicate S. Pullorum in poultry farms, it is necessary to establish an efficient met ...
DOI:
10.1186/s12917-018-1753-0

56. Spleen and head kidney differential gene expression patterns in trout infected with Lactococcus garvieae correlate with spleen granulomas

Author:
Castro, Rosario; Coll, Julio; Blanco, María del Mar; Rodriguez-Bertos, Antonio; Jouneau, Luc; Fernández-Garayzábal, José Francisco; Gibello, Alicia
Source:
Veterinary research 2019 v.50 no.1 pp. 32
ISSN:
1297-9716
Subject:
B-lymphocytes; Lactococcus garvieae; Oncorhynchus mykiss; antibodies; antibody formation; aquaculture; control methods; fish farms; gene expression regulation; genes; granuloma; immunoglobulin M; inflammation; kidneys; macrophages; neutrophils; pathogens; risk; signs and symptoms (animals and humans); spleen; transcriptome; trout
Abstract:
... Lactococcus garvieae is a significant pathogen in aquaculture with a potential zoonotic risk. To begin to characterize the late immune response of trout to lactococcosis, we selected infected individuals showing clinical signs of lactococcosis. At the time lactococcosis clinical signs appeared, infection by L. garvieae induced a robust inflammatory response in the spleen of rainbow trout, which co ...
DOI:
10.1186/s13567-019-0649-8

57. Systemic tuberculosis by MYCOBACTERIUM BOVIS in a free-ranging MARSICAN brown bear (URSUS ARCTOS MARSICANUS): a Case report

Author:
Fico, Rosario; Mariacher, Alessia; Franco, Alessia; Eleni, Claudia; Ciarrocca, Erika; Pacciarini, Maria Lodovica; Battisti, Antonio
Source:
BMC veterinary research 2019 v.15 no.1 pp. 152
ISSN:
1746-6148
Subject:
Bacilli; Mycobacterium bovis; Ursus americanus; Ursus arctos; adults; adverse effects; algorithms; bovine tuberculosis; carnivores; case studies; cattle; conservation areas; death; females; histopathology; host range; intestines; kidneys; liver; lungs; lymph nodes; monitoring; national parks; necropsy; pathogens; polymerase chain reaction; sequence analysis; signs and symptoms (animals and humans); spleen; tissues; wildlife; wildlife diseases; Italy
Abstract:
... BACKGROUND: Mycobacterium bovis is known to have a wide host range and has been isolated from numerous free-ranging wildlife species, carnivores included. In bears, M. bovis has been previously reported only from a culture of pooled lymph nodes of a black bear (Ursus americanus) in the absence of lesions. The aims of this study were to describe gross and microscopic pathological findings of M. bov ...
DOI:
10.1186/s12917-019-1910-0

58. The tree shrew is a promising model for the study of influenza B virus infection

Author:
Yuan, Bing; Yang, Chunguang; Xia, Xueshan; Zanin, Mark; Wong, Sook-san; Yang, Fan; Chang, Jixiang; Mai, Zhitong; Zhao, Jin; Zhang, Yunhui; Li, Runfeng; Zhong, Nanshan; Yang, Zifeng
Source:
Virology journal 2019 v.16 no.1 pp. 77
ISSN:
1743-422X
Subject:
Influenza A virus; Influenza B virus; Scandentia; animal models; cytokines; disease outbreaks; ferrets; influenza; messenger RNA; mice; nose; plant diseases and disorders; plant viruses; secretion; seroconversion; signs and symptoms (animals and humans); tissues; viral load; weight loss
Abstract:
... BACKGROUND: Influenza B virus is a main causative pathogen of annual influenza epidemics, however, research on influenza B virus in general lags behind that on influenza A viruses, one of the important reasons is studies on influenza B viruses in animal models are limited. Here we investigated the tree shrew as a potential model for influenza B virus studies. METHODS: Tree shrews and ferrets were ...
DOI:
10.1186/s12985-019-1171-3

59. Transmission of Cytauxzoon felis to domestic cats by Amblyomma americanum nymphs

Author:
Allen, Kelly E.; Thomas, Jennifer E.; Wohltjen, Megan L.; Reichard, Mason V.
Source:
Parasites & vectors 2019 v.12 no.1 pp. 28
ISSN:
1756-3305
Subject:
Amblyomma americanum; Cytauxzoon felis; Dermacentor variabilis; Lynx rufus; Protozoa; adults; blood; cat diseases; cats; ecdysis; larvae; macrophages; necropsy; nymphs; parasitemia; parasites; polymerase chain reaction; repletion; schizonts; signs and symptoms (animals and humans); spleen
Abstract:
... BACKGROUND: Successful Cytauxzoon felis transmission studies have occurred using Amblyomma americanum adults acquisition-fed as nymphs on an experimentally infected domestic cat or Dermacentor variabilis adults fed as nymphs on a splenectomized bobcat. Here, we evaluated A. americanum and D. variabilis nymphs acquisition-fed as larvae on a C. felis-infected carrier domestic cat for competence to t ...
DOI:
10.1186/s13071-018-3276-8

60. Use of miltefosine to treat canine visceral leishmaniasis caused by Leishmania infantum in Brazil

Author:
dos Santos Nogueira, Fabio; Avino, Valdir Carlos; Galvis-Ovallos, Fredy; Pereira-Chioccola, Vera Lucia; Moreira, Marcio Antonio Batistella; Romariz, Ana Paula Peres Lopes; Molla, Leticia M.; Menz, Ingrid
Source:
Parasites & vectors 2019 v.12 no.1 pp. 79
ISSN:
1756-3305
Subject:
Leishmania infantum; Lutzomyia longipalpis; adults; arthropods; cell biology; clinical examination; dog diseases; dogs; females; hosts; infectious diseases; laboratory experimentation; parasite load; parasites; pathogenicity; quantitative polymerase chain reaction; remission; signs and symptoms (animals and humans); visceral leishmaniasis; xenodiagnosis; Brazil; North America
Abstract:
... BACKGROUND: Visceral leishmaniasis (VL) is an infectious disease with a variety of clinical signs. The main form of parasite transmission to humans and other mammalian hosts is through the bite of infected arthropod females with Lutzomyia longipalpis serving as the main vector in the Americas. Dogs are the main urban domestic reservoirs of the parasite and the main source of vector infection due t ...
DOI:
10.1186/s13071-019-3323-0

61. Virulence of three European highly pathogenic H7N1 and H7N7 avian influenza viruses in Pekin and Muscovy ducks

Author:
Scheibner, David; Blaurock, Claudia; Mettenleiter, Thomas C.; Abdelwhab, Elsayed M.
Source:
BMC veterinary research 2019 v.15 no.1 pp. 142
ISSN:
1746-6148
Subject:
Cairina moschata; Influenza A virus; Muscovy; Pekin; cloaca; death; ducklings; morbidity; mortality; respiratory system; signs and symptoms (animals and humans); virulence; viruses
Abstract:
... BACKGROUND: There is paucity of data on the virulence of highly pathogenic (HP) avian influenza viruses (AIV) H7 in ducks compared to HPAIV H5. Here, the virulence of HPAIV H7N1 (designated H7N1-FPV34 and H7N1-It99) and H7N7 (designated H7N7-FPV27) was assessed in Pekin and/or Muscovy ducklings after intrachoanal (IC) or intramuscular (IM) infection. RESULTS: The morbidity rate ranged from 60 to 1 ...
DOI:
10.1186/s12917-019-1899-4

62. Status of vaccine research and development for Clostridium difficile

Author:
Riley, T.V.; Lyras, D.; Douce, G.R.
Source:
Vaccine 2019 v.37 no.50 pp. 7300-7306
ISSN:
0264-410X
Subject:
Clostridium difficile; antibiotics; clinical trials; cost effectiveness; digestive system; dysbiosis; germination; income; intestinal microorganisms; neutralization; neutralizing antibodies; research and development; signs and symptoms (animals and humans); therapeutics; toxins; vaccines
Abstract:
... Clostridium difficile associated disease is fundamentally associated with dysbiosis of the gut microbiome as a consequence of antibiotic use. This is because this sporulating, obligate anaerobe germinates and proliferates rapidly in the dysbiotic gut, which is an indirect consequence of their use. During its growth, C. difficile produces two toxins, toxin A (TcdA) and toxin B (TcdB), which are res ...
DOI:
10.1016/j.vaccine.2019.02.052

63. Enzootic nasal adenocarcinoma in sheep: An update

Author:
De las Heras, M.; Ortín, A.; Borobia, M.; Navarro, T.
Source:
Small ruminant research 2019 v.180 pp. 131-134
ISSN:
0921-4488
Subject:
Jaagsiekte sheep retrovirus; Ovine enzootic nasal tumor virus; adenocarcinoma; antigens; antiserum; deformation; distress; enzootic diseases; genes; goats; immune response; immunohistochemistry; mucosa; neutralizing antibodies; nose; polymerase chain reaction; secretion; sheep; signs and symptoms (animals and humans); skull; viruses; Australia; New Zealand
Abstract:
... Enzootic nasal adenocarcinoma of sheep (ENAS) is a contagious tumor of the ethmoid turbinate mucosa. The disease occurs naturally in all continents except Australia and New Zealand. Similar disease has been described in goats. ENAS is aetiologically associated with enzootic nasal tumor virus 1 (ENTV-1) a type Beta retrovirus and closely related to jaagsiekte sheep retrovirus (JSRV) and enzootic na ...
DOI:
10.1016/j.smallrumres.2019.04.018

64. Branchial bioenergetics dysfunction as a relevant pathophysiological mechanism in freshwater silver catfish (Rhamdia quelen) experimentally infected with Flavobacterium columnare

Author:
Baldissera, Matheus D.; Souza, Carine F.; Dias, Juliane B.; Da Silva, Tatiane O.; Tavares, Guilherme C.; Valladão, Gustavo M.R.; da Silva, Aleksandro S.; Verdi, Camila Marina; Santos, Roberto C.V.; Vencato, Marina; da Veiga, Marcelo L.; da Rocha, Maria Izabel U.M.; Cunha, Mauro A.; Baldisserotto, Bernardo
Source:
Microbial pathogenesis 2019
ISSN:
0882-4010
Subject:
Flavobacterium columnare; Rhamdia quelen; adenosine triphosphate; adenylate kinase; aquaculture industry; bacteria; columnaris disease; creatine kinase; discoloration; energy metabolism; enzyme activity; etiological agents; financial economics; freshwater; freshwater fish; gills; homeostasis; lipid peroxidation; mitochondria; mortality; necrosis; pathogenesis; pyruvate kinase; reactive oxygen species; signs and symptoms (animals and humans); sodium; sodium-potassium-exchanging ATPase
Abstract:
... Flavobacterium columnare, the causative agent of columnaris disease, is a serious bacterial disease responsible for causing devastating mortality rates in several species of freshwater fish, leading to severe economic losses in the aquaculture industry. Notwithstanding the enormous impacts this disease can have, very little is known regarding the interaction between the host and bacterium in terms ...
DOI:
10.1016/j.micpath.2019.103817

65. Overview of rabies post-exposure prophylaxis access, procurement and distribution in selected countries in Asia and Africa, 2017–2018

Author:
Sreenivasan, N.; Li, A.; Shiferaw, M.; Tran, C.H.; Wallace, R.; Blanton, J.; Knopf, L.; Abela-Ridder, B.; Hyde, T.; Siddiqi, U.R.; Tahmina, S.; Penjor, K.; Sovann, L.; Doeurn, Y.; Sim, K.; Houssiere, V.; Tejiokem, M.; Mindekem, R.; Yu, L.; Wenwu, Y.; Benié, J.; Tetchi, M.; Tiembre, I.; Deressa, A.; Haile, A.; Hurisa, B.; Yawson, N.A.; Ohene, S.A.; Sudarshan, M.K.; Narayana, A.; Mwatondo, A.; Thumbi, S.M.; Edosoa, G.; Baril, L.; Ramiandrasoa, R.; Rajeev, M.; Fofana, M.S.; Traore, A.; Matchaya, M.; Burdon Bailey, J.L.; Yale, G.; Dolgorkhand, A.; Tsogbadrakh, N.; Ochirpurev, A.; Shrestha, K.; Balami, J.; Qureshi, H.; Salahuddin, N.; Villalon, E.; Blumberg, L.; Gunesekara, A.; Changalucha, Joel; Nguyen, H.
Source:
Vaccine 2019 v.37 pp. A6
ISSN:
0264-410X
Subject:
World Health Organization; childhood; disease control; funding; humans; immunoglobulins; monitoring; patients; people; public sector; rabies; signs and symptoms (animals and humans); vaccines; washing; zoonoses; Africa; Asia
Abstract:
... Rabies is a neglected zoonotic disease with a global burden of approximately 59,000 human deaths a year. Once clinical symptoms appear, rabies is almost invariably fatal; however, with timely and appropriate post-exposure prophylaxis (PEP) consisting of wound washing, vaccine, and in some cases rabies immunoglobulin (RIG), the disease is almost entirely preventable. Access to PEP is limited in man ...
DOI:
10.1016/j.vaccine.2019.04.024

66. Salivary and hair cortisol as biomarkers of emotional and behavioral symptoms in 6–9 year old children

Author:
Golub, Yulia; Kuitunen-Paul, Sören; Panaseth, Kerstin; Stonawski, Valeska; Frey, Stefan; Steigleder, Ruth; Grimm, Jennifer; Goecke, Tamme W.; Fasching, Peter A.; Beckmann, Matthias W.; Kornhuber, Johannes; Kratz, Oliver; Heinrich, Hartmut; Moll, Gunter H.; Eichler, Anna
Source:
Physiology & behavior 2019 v.209 pp. 112584
ISSN:
0031-9384
Subject:
adolescents; behavior problems; biomarkers; children; cognition; cortisol; signs and symptoms (animals and humans)
Abstract:
... The aim of the present work is to investigate the association of salivary and cumulative cortisol levels with emotional and behavioral symptoms in a Franconian Cognition and Emotion Studies (FRANCES) general population cohort of 158 6- to 9 year old children. Salivary cortisol values were measured by one-day diurnal cortisol profile, whereas cumulative cortisol was estimated via one-month hair cor ...
DOI:
10.1016/j.physbeh.2019.112584

67. A case of otitis interna in a ferret (Mustela putorius furo)

Author:
Desprez, Isabelle; Donnelly, Thomas M.; Mayousse, Vincent; Thibaud, Jean-Laurent; Parker, Dennilyn L.; Pignon, Charly
Source:
Journal of exotic pet medicine 2019 v.31 pp. 104-107
ISSN:
1557-5063
Subject:
Mustela putorius; appetite; blood; blood chemistry; brain; case studies; computed tomography; ears; enrofloxacin; females; ferrets; head; hospitals; image analysis; intravenous injection; magnetic resonance imaging; neurological examination; otitis media; prednisolone; signs and symptoms (animals and humans)
Abstract:
... Vestibular signs are rarely reported in ferrets. This report documents the successful diagnosis and management of an otitis interna without otitis media in a ferret. A 4-year-old deslorelin-implanted female ferret presented with an acute-onset, 2-day history of circling and falling to the right, and a diminished appetite. Neurologic examination revealed a right-sided head tilt associated with bila ...
DOI:
10.1053/j.jepm.2019.08.003

68. Antimicrobial activities of chitosan nanoparticles against pathogenic microorganisms in Nile tilapia, Oreochromis niloticus

Author:
Abdel-Razek, Nashwa
Source:
Aquaculture international 2019 v.27 no.5 pp. 1315-1330
ISSN:
0967-6120
Subject:
Aeromonas hydrophila; Aeromonas sobria; Aspergillus flavus; Aspergillus fumigatus; Aspergillus niger; Candida; Fusarium; Mucor; Oreochromis niloticus; Pseudomonas aeruginosa; Pseudomonas fluorescens; Staphylococcus aureus; Streptococcus agalactiae; antimicrobial properties; bacteria; cell membranes; chitosan; cytoplasm; diet; digestive system; dose response; fish; fish diseases; fungi; gelation; hemorrhage; intraperitoneal injection; lethal dose; minimum inhibitory concentration; mortality; nanoparticles; necrosis; septicemia; signs and symptoms (animals and humans); spleen; swimming; therapeutics; transmission electron microscopes; tripolyphosphates; virulent strains; zeta potential
Abstract:
... Nanotechnology is a recent unique technique generally used for nutrition and therapy purposes among others. In this respect, the present study was carried out to evaluate the antimicrobial activity of chitosan nanoparticles (CNP) against various microorganisms (fungi and bacteria) isolated from diseased or health Nile tilapia, Oreochromis niloticus. The CNP was prepared based on the ionic gelation ...
DOI:
10.1007/s10499-019-00388-0

69. A systematic review and meta-analysis of randomized controlled trials to evaluating the trend of cytokines to vitamin A supplementation in autoimmune diseases

Author:
Harirchian, Mohammad Hossein; Mohammadpour, Zinat; Fatehi, Farzad; Firoozeh, Negar; Bitarafan, Sama
Source:
Clinical nutrition 2019 v.38 no.5 pp. 2038-2044
ISSN:
0261-5614
Subject:
atherosclerosis; autoimmune diseases; blood serum; gene expression; gene expression regulation; interferon-gamma; interleukin-17; meta-analysis; patients; randomized clinical trials; sclerosis; signs and symptoms (animals and humans); systematic review; transforming growth factor beta; vitamin A
Abstract:
... Vitamin A is considered as a supplement that effect on autoimmune diseases. We aimed to systematically review the effect of vitamin A on cytokines in patients with autoimmune disease.Two researchers searched Scopus and PubMed until May 2018. Researchers extracted data from 6 eligible published papers. Extracted data included the gene expression of the inflammatory and anti-inflammatory cytokines.F ...
DOI:
10.1016/j.clnu.2018.10.026

70. A Toxoplasma gondii strain isolated in Okinawa, Japan shows high virulence in Microminipigs

Author:
Taniguchi, Yuji; Yanagihara, Itaru; Nakura, Yukiko; Ichikawa, Chihiro; Saito, Taizo; Appiah-Kwarteng, Cornelia; Matsuzaki, Motomichi; Fukumoto, Junpei; Nagamune, Kisaburo; Kyan, Hisako; Takasu, Masaki; Kitoh, Katsuya; Takashima, Yasuhiro
Source:
Parasitology international 2019 v.72 pp. 101935
ISSN:
1383-5769
Subject:
Toxoplasma gondii; histology; liver; mice; necrosis; pneumonia; signs and symptoms (animals and humans); swine; tachypnea; virulence; Ryukyu Archipelago
Abstract:
... Toxoplasma gondii strains have been isolated all over the world and their virulence has been examined mainly using laboratory mice. However, T. gondii differs in virulence depending on the host animal species. Therefore, to evaluate the virulence of each strain in domestic animals, it is necessary to examine using not only mice but also the concerned animals. We have shown that TgCatJpOk4, a T. go ...
DOI:
10.1016/j.parint.2019.101935

71. Diagnosis and long-term management of blastomycosis in two ferrets (Mustela putorius furo)

Author:
Le, Kim; Beaufrère, Hugues; Laniesse, Delphine; Blois, Shauna; Kabakchiev, Claudia; Smith, Dale A.; Finck, Cyrielle; Chalmers, Heather; Brochu, Nancy; Keller, Stefan; Gaitero, Luis
Source:
Journal of exotic pet medicine 2019 v.31 pp. 39-44
ISSN:
1557-5063
Subject:
Blastomyces; Mustela putorius; antigens; blastomycosis; blood; carcinoma; cell biology; central nervous system; cerebrospinal fluid; disease progression; ferrets; fungi; histopathology; image analysis; magnetic resonance imaging; males; prednisolone; radiography; signs and symptoms (animals and humans); therapeutics; ultrasonics; North America
Abstract:
... Blastomycosis is an uncommon fungal infection endemic to certain parts of Eastern North America. Blastomycosis has been reported twice before in ferrets, but both cases died shortly after diagnosis. Case description: Two male neutered ferrets (Mustela putorius furo) from the same household, 4 and 1½-years of age, presented for respiratory signs. The diagnostic work-up included thoracic radiographs ...
DOI:
10.1053/j.jepm.2019.06.007

72. Dietary intake, body composition and metabolic parameters in women with polycystic ovary syndrome

Author:
Cunha, Nayara Bernardes da; Ribeiro, Camila Toffoli; Silva, Catarina Mendes; Rosa-e-Silva, Ana Carolina Japur de Sá; De-Souza, Daurea Abadia
Source:
Clinical nutrition 2019 v.38 no.5 pp. 2342-2348
ISSN:
0261-5614
Subject:
Adequate Intakes; animal ovaries; body fat; body mass index; body weight changes; case-control studies; chronic diseases; dietary fiber; dual-energy X-ray absorptiometry; eating habits; food intake; food records; glucose; glucose tolerance tests; homeostasis; insulin; insulin resistance; metabolism; models; nutrition risk assessment; overweight; patients; polycystic ovary syndrome; signs and symptoms (animals and humans); women
Abstract:
... Overweight polycystic ovary syndrome (PCOS) patients present exacerbation of clinical symptoms and increased risk for chronic diseases. The effects of inadequate dietary intake have been investigated in body weight gain in PCOS women. The aim of this study was to evaluate the dietary pattern and to analyze possible associations with the metabolism and body composition in PCOS women.A case–control ...
DOI:
10.1016/j.clnu.2018.10.012

73. Individual monitoring of immune response in Atlantic salmon Salmo salar following experimental infection with piscine myocarditis virus (PMCV), agent of cardiomyopathy syndrome (CMS)

Author:
Monte, Milena; Urquhart, Katy; Evensen, Øystein; Secombes, Christopher J.; Collet, Bertrand
Source:
Developmental and comparative immunology 2019 v.99 pp. 103406
ISSN:
0145-305X
Subject:
Salmo salar; Totiviridae; blood cells; blood sampling; cardiomyopathy; double-stranded RNA; gene expression regulation; genes; health status; heart; histology; histopathology; immune response; models; monitoring; myocarditis; pathogens; quantitative polymerase chain reaction; salmon; signs and symptoms (animals and humans); transcriptome; viral load; viruses
Abstract:
... Piscine myocarditis virus (PCMV) is a double-stranded RNA virus structurally similar to the Totiviridae family. PCMV is the causative agent of cardiomyopathy syndrome (CMS), a severe cardiac disease that affects farmed Atlantic salmon (Salmo salar). A recent study characterized the host immune response in infected salmon through a transcriptome immune profiling, which confirmed a high regulation o ...
DOI:
10.1016/j.dci.2019.103406

74. NDM-1-producing Escherichia coli isolated from pigs induces persistent infection with limited pathogenicity

Author:
Zhao, Zhanqin; Liao, Chengshui; Chang, Shikai; Ding, Ke; Liu, Zhijun; Xue, Yun
Source:
Microbial pathogenesis 2019 v.135 pp. 103620
ISSN:
0882-4010
Subject:
Escherichia coli; antibiotics; bacteria; brain; chronic diseases; duodenum; feces; heart; human health; kidneys; liver; lungs; lymph nodes; minimum inhibitory concentration; multiple drug resistance; pathogenicity; piglets; signs and symptoms (animals and humans); spleen; stomach; swine diseases; China
Abstract:
... NDM-1-producing Enterobacteriaceae are multidrug-resistant bacteria, also called superbacteria, that have become important global human health threats in recent years. However, data about NDM-1-producing bacteria in animals are rare. In this study, an NDM-1-producing Escherichia coli isolate (designated E120413) was obtained from pigs in Henan province, China in 2012. The susceptibility of E. coli ...
DOI:
10.1016/j.micpath.2019.103620

75. Retrospective diagnosis of archived marine fish experienced unexplained mortality reveals dual infections of Nocardia seriolae and Streptococcus iniae

Author:
Nguyen, Vuong Viet; Rodkhum, Channarong; Senapin, Saengchan; Dong, Ha Thanh
Source:
Aquaculture international 2019 v.27 no.5 pp. 1503-1512
ISSN:
0967-6120
Subject:
Epinephelus coioides; Gram-positive bacteria; Lates calcarifer; Nocardia seriolae; Streptococcus iniae; Trachinotus blochii; disease diagnosis; grouper; marine fish; mixed infection; models; mortality; pathogens; polymerase chain reaction; ribosomal RNA; sequence homology; signs and symptoms (animals and humans); tissues; South East Asia
Abstract:
... Due to the limitation of accessible laboratory facilities for disease diagnosis at the time of the events, clinical samples of snubnose pompano (Trachinotus blochii) and orange-spotted grouper (Epinephelus coioides) were frozen preserved for retrospective investigation. This study employed a simple challenged test using crude homogenate prepared from the long-term frozen preserved tissues (~ 16 mo ...
DOI:
10.1007/s10499-019-00403-4

76. Subchronic toxicity study in BALBc mice of enterocin AS-48, an anti-microbial peptide produced by Enterococcus faecalis UGRA10

Author:
Baños, Alberto; García, J. David; Núñez, Cristina; Mut-Salud, Nuria; Ananou, Samir; Martínez-Bueno, Manuel; Maqueda, Mercedes; Valdivia, Eva
Source:
Food and chemical toxicology 2019 v.132 pp. 110667
ISSN:
0278-6915
Subject:
Enterococcus faecalis; adverse effects; animal models; antimicrobial peptides; blood chemistry; body weight; diet; foods; heart; hematology; hepatocytes; histopathology; intestines; kidneys; liver; mice; nisin; signs and symptoms (animals and humans); spleen; subchronic toxicity; urinalysis; vacuoles
Abstract:
... Few studies have examined the use of animal models to evaluate the in-vivo toxicity of antimicrobial peptides, but such research is essential to their safe use in foods. This study was performed to evaluate any adverse effects of enterocin AS-48, a circular bacteriocin produced by Enterococcus strains, when administered to BALB/c mice at concentrations of 50, 100, and 200 mg/kg in the diet for 90 ...
DOI:
10.1016/j.fct.2019.110667

77. Transcriptome comparative analysis of immune tissues from asymptomatic and diseased Epinephelus moara naturally infected with nervous necrosis virus

Author:
Wang, Linna; Tian, Yongsheng; Cheng, Meiling; Li, Zhentong; Li, Shangyong; Wu, Yuping; Zhang, Jingjing; Ma, Wenhui; Li, Wensheng; Pang, Zunfang; Zhai, Jieming
Source:
Fish & shellfish immunology 2019 v.93 pp. 99-107
ISSN:
1050-4648
Subject:
Betanodavirus; Epinephelus; adhesion; antibodies; cytotoxicity; disease control; fish farms; gene expression regulation; genetic markers; grouper; kidneys; liver; major histocompatibility complex; microsatellite repeats; necrosis; pathogenesis; reverse transcriptase polymerase chain reaction; screening; signs and symptoms (animals and humans); spleen; tissues; transcriptome; transcriptomics; unigenes
Abstract:
... Epinephelus moara is an economically important fish in Southeast Asian countries but is suffering from nervous necrosis virus (NNV) infection. A deeper understanding of the host-NNV interaction mechanisms makes sense for disease control, however, at present, the pathogenesis of natural NNV infection and the resistance mechanism in host remains poorly understood. In this study, asymptomatic and dis ...
DOI:
10.1016/j.fsi.2019.07.020

78. Acute/Subacute and Sub-Chronic Oral Toxicity of a Hidroxytyrosol-Rich Virgin Olive Oil Extract

Author:
Rodríguez-Lara, Avilene; Mesa, María Dolores; Aragón-Vela, Jerónimo; Casuso, Rafael A.; Casals Vázquez, Cristina; Zúñiga, Jesús M.; Huertas, Jesús R.
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
adverse effects; body weight; drinking water; females; functional foods; histopathology; males; rats; signs and symptoms (animals and humans); subacute toxicity; virgin olive oil
Abstract:
... The objective of this study was to determine the acute (one single dose), subacute (14 days), and sub-chronic (90 days) toxicity of an aqueous virgin olive oil (VOO) extract rich in hydroxytyrosol in rats. For acute/subacute toxicity, rats were divided into three groups. The control group received distilled water (n = 9), another experimental group received a single dose of 300 mg/kg (n = 3), and ...
DOI:
10.3390/nu11092133

79. Selenium, Selenoproteins and Viral Infection

Author:
Guillin, Olivia M.; Vindry, Caroline; Ohlmann, Théophile; Chavatte, Laurent
Source:
Nutrients 2019 v.11 no.9
ISSN:
2072-6643
Subject:
antioxidant activity; fowl pox; genome; glutathione peroxidase; homeostasis; models; nutrient deficiencies; nutrients; nutritional status; oxidative stress; pathogenicity; reactive oxygen species; selenium; selenocysteine; selenoproteins; signs and symptoms (animals and humans); thioredoxins; virus replication; viruses
Abstract:
... Reactive oxygen species (ROS) are frequently produced during viral infections. Generation of these ROS can be both beneficial and detrimental for many cellular functions. When overwhelming the antioxidant defense system, the excess of ROS induces oxidative stress. Viral infections lead to diseases characterized by a broad spectrum of clinical symptoms, with oxidative stress being one of their hall ...
DOI:
10.3390/nu11092101

80. Anaplasma ovis in sheep: Experimental infection, vertical transmission and colostral immunity

Author:
Jiménez, C.; Benito, A.; Arnal, J.L.; Ortín, A.; Gómez, M.; López, A.; Villanueva-Saz, S.; Lacasta, D.
Source:
Small ruminant research 2019 v.178 pp. 7-14
ISSN:
0921-4488
Subject:
Anaplasma ovis; anaplasmosis; anemia; antibodies; bacteria; blood; blood sampling; cachexia; colostral immunity; colostrum; disease transmission; enzyme-linked immunosorbent assay; erythrocyte count; ewes; fever; flocks; humoral immunity; immune response; lactation; lambing; lambs; microbial load; mucosa; pregnancy; quantitative polymerase chain reaction; signs and symptoms (animals and humans); staining; weight loss; Spain
Abstract:
... Ovine anaplasmosis is caused by the obligate intraerythrocytic bacteria Anaplasma ovis and the disease is characterized by anaemia, weight loss and weakness. A severe outbreak of ovine anaplasmosis was diagnosed for the first time in Spain in 2014 and, subsequently, a research was developed in order to increase de knowledge of this not-well-known disease.An experimental infection with Anaplasma ov ...
DOI:
10.1016/j.smallrumres.2019.07.003

81. An equine disease diagnosis expert system based on improved reasoning of evidence credibility

Author:
Gao, Hongyan; Jiang, Guimiao; Gao, Xiang; Xiao, Jianhua; Wang, Hongbin
Source:
Information processing in agriculture 2019 v.6 no.3 pp. 414-423
ISSN:
2214-3173
Subject:
databases; disease diagnosis; farmers; horse diseases; horses; models; signs and symptoms (animals and humans); uncertainty; veterinarians; China
Abstract:
... In China, there is a troubling shortage of well-trained equine veterinarians, leaving the needs of many equine farmers unmet. This is especially true with respect to the diagnosis of equine diseases. To solve this shortcoming, an equine disease diagnosis expert system was developed. For the aspect of knowledge representation, the structure of equine disease diagnosis knowledge was analyzed using a ...
DOI:
10.1016/j.inpa.2018.11.003

82. Bartonella diversity and zoonotic potential in indigenous Tete Veld rats (Aethomys ineptus) from South Africa

Author:
Hatyoka, Luiza M.; Brettschneider, Helene; Bennett, Nigel C.; Kleynhans, Dewald J.; Muteka, Sachariah P.; Bastos, Armanda D.S.
Source:
Infection, genetics, and evolution 2019 v.73 pp. 44-48
ISSN:
1567-1348
Subject:
Bartonella elizabethae; DNA; Rattus; biodiversity; conservation areas; data collection; ectoparasites; genes; heart; indigenous species; mixed infection; multilocus sequence typing; patients; phylogeny; polymerase chain reaction; public health; rats; signs and symptoms (animals and humans); sympatry; vector-borne diseases; zoonoses; Eastern Africa; South Africa
Abstract:
... Bartonellosis is a vector-borne disease that is often misdiagnosed due to a broad range of clinical symptoms, compounded by a lack of awareness regarding the prevalence, diversity and public health impacts of regional strains. Despite recent PCR-based confirmation of Bartonella in 9.7% of non-malarial, acute febrile patients in South Africa, data regarding reservoirs of infection are limited. As t ...
DOI:
10.1016/j.meegid.2019.04.012

83. Genetic characterization and phylogenetic analysis of rabbit hemorrhagic disease virus isolated in Tunisia from 2015 to 2018

Author:
Rahali, Nadia; Sghaier, Soufien; Kbaier, Houaida; Zanati, Amira; Bahloul, Chokri
Source:
Archives of virology 2019 v.164 no.9 pp. 2327-2332
ISSN:
0304-8608
Subject:
Rabbit hemorrhagic disease virus; control methods; genotype; monitoring; mutation; phenotype; phylogeny; rabbits; signs and symptoms (animals and humans); vaccination; vaccines; Tunisia
Abstract:
... Two distinct genotypes responsible for rabbit hemorrhagic disease (RHD) are reported, GI.1 (RHDV) and GI.2 (RHDV2). Vaccines based on these two genotypes are only partially cross-protective. Hence, knowing which genotype is circulating is important for appropriate control measures. We have investigated 25 field samples isolated between 2015 and 2018 from rabbits with clinical signs of RHD. Only GI ...
DOI:
10.1007/s00705-019-04311-z

84. Incidence and clinical signs of owner‐reported equine laminitis in a cohort of horses and ponies in Great Britain

Author:
Pollard, D.; Wylie, C. E.; Newton, J. R.; Verheyen, K. L. P.
Source:
Equine veterinary journal 2019 v.51 no.5 pp. 587-594
ISSN:
0425-1644
Subject:
Internet; confidence interval; epidemiological studies; forelimbs; horses; laminitis; risk; signs and symptoms (animals and humans); veterinarians; Great Britain
Abstract:
... BACKGROUND: Previous robust epidemiological studies of equine laminitis have utilised only veterinary‐diagnosed episodes of disease, potentially underestimating true disease frequency. OBJECTIVES: To estimate the incidence of, and describe clinical signs associated with, owner‐reported active laminitis in horses/ponies, using both veterinary‐diagnosed and nonveterinary‐diagnosed episodes. STUDY DE ...
DOI:
10.1111/evj.13059

85. Misoprostol is superior to combined omeprazole‐sucralfate for the treatment of equine gastric glandular disease

Author:
Varley, G.; Bowen, I. M.; Habershon‐Butcher, J. L.; Nicholls, V.; Hallowell, G. D.
Source:
Equine veterinary journal 2019 v.51 no.5 pp. 575-580
ISSN:
0425-1644
Subject:
diet; drugs; gastroscopy; horses; pharmacodynamics; questionnaires; signs and symptoms (animals and humans); sports
Abstract:
... BACKGROUND: Previous studies have demonstrated a poor response to healing of gastric glandular lesions with oral omeprazole and other medications. OBJECTIVES: To evaluate the efficacy of two novel treatments (misoprostol [M] and combined omeprazole‐sucralfate [OS]) in horses for gastric glandular disease. STUDY DESIGN: Prospective, clinical study. METHODS: Sixty‐three sports horses with grade >1/4 ...
DOI:
10.1111/evj.13087

86. Molecular characterization of a novel reassortment Mammalian orthoreovirus type 2 isolated from a Florida white-tailed deer fawn

Author:
Ahasan, Mohammad Shamim; Subramaniam, Kuttichantran; Sayler, Katherine A.; Loeb, Julia C.; Popov, Vsevolod L.; Lednicky, John A.; Wisely, Samantha M.; Campos Krauer, Juan M.; Waltzek, Thomas B.
Source:
Virus research 2019 v.270 pp. 197642
ISSN:
0168-1702
Subject:
Mammalian orthoreovirus; Odocoileus virginianus; Panthera leo; RNA; cDNA libraries; capsid; cytopathogenicity; cytoplasm; diarrhea; digestive system diseases; fawns; genes; glutaraldehyde; heart; humans; liver; mink; monitoring; necropsy; nucleotide sequences; phylogeny; signs and symptoms (animals and humans); spleen; tissues; transmission electron microscopy; urine; virion; wildlife; China; Florida; Japan
Abstract:
... Mammalian orthoreovirus (MRV) is the type species of the genus Orthoreovirus and causes a range of significant respiratory, nervous or enteric diseases in humans and animals. In 2016 a farmed white-tailed deer (Odocoileus virginianus) fawn became ill, displaying clinical signs of lethargy, dehydration, and profuse foul-smelling diarrhea. A necropsy was performed after the three-week-old fawn died ...
DOI:
10.1016/j.virusres.2019.197642

87. Preclinical safety of ginsenoside compound K: Acute, and 26-week oral toxicity studies in mice and rats

Author:
Gao, Yonglin; Wang, Tong; Wang, Guangfei; Li, Guisheng; Sun, Chengfeng; Jiang, Zhumao; Yang, Jianrong; Li, Yanshen; You, Yanli; Wu, Xuran; Sun, Liqin; Wang, Hongbo; Li, Chunmei; Tian, Jingwei; Zhu, Jing; Wang, Kezhou; Cho, Susan
Source:
Food and chemical toxicology 2019 v.131 pp. 110578
ISSN:
0278-6915
Subject:
acute toxicity; alanine transaminase; alkaline phosphatase; body weight; eating habits; females; fur; ginsenosides; hepatotoxicity; histopathology; hydrolysates; kidneys; liver; males; mice; mortality; necrosis; nephrotoxicity; no observed adverse effect level; rats; signs and symptoms (animals and humans); soil bacteria; toxicity testing; urinalysis; weight loss
Abstract:
... Ginsenoside compound K (CK) is a hydrolysate of ginsenosides in the soil bacteria. This study evaluated the toxicity of CK as acute and the 26-week repeated-dose. The results of acute toxicity show that CK administered orally to rats and mice did not cause mortality or toxicity at the maximum dosage of 8 g/kg and 10 g/kg, respectively. In the toxicity study for 26-week, rats were administered with ...
DOI:
10.1016/j.fct.2019.110578

88. Presence of bluetongue and epizootic hemorrhagic disease viruses in Egypt in 2016 and 2017

Author:
Ahmed, Sahar; Mahmoud, Mohamed Abd El-Fatah; Viarouge, Cyril; Sailleau, Corinne; Zientara, Stephan; Breard, Emmanuel
Source:
Infection, genetics, and evolution 2019 v.73 pp. 221-226
ISSN:
1567-1348
Subject:
antibodies; blood sampling; bluetongue; cattle; enzyme-linked immunosorbent assay; genome; goats; herds; midges; nucleotide sequences; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; seroprevalence; serotypes; sheep; sheep pox; signs and symptoms (animals and humans); vaccines; Egypt; Israel
Abstract:
... BTV and EHDV are closely-related orbiviruses that are transmitted between domestic and wild ruminants via the bites of hematophagous midges. Previous studies have reported seropositivity against BTV antibodies in sheep and goats in two Egyptian governorates (Beni Suef and Menoufia). However, no recent data are available on the BTV serotype(s) circulating in Egypt and the likely presence of EHDV ha ...
DOI:
10.1016/j.meegid.2019.04.033

89. Protective effects induced by alcoholic Phlomis fruticosa and Phlomis herba‐venti extracts in isolated rat colon: Focus on antioxidant, anti‐inflammatory, and antimicrobial activities in vitro

Author:
Ferrante, Claudio; Recinella, Lucia; Ronci, Maurizio; Orlando, Giustino; Di Simone, Simonetta; Brunetti, Luigi; Chiavaroli, Annalisa; Leone, Sheila; Politi, Matteo; Tirillini, Bruno; Angelini, Paola; Covino, Stefano; Venanzoni, Roberto; Vladimir‐Knežević, Sanda; Menghini, Luigi
Source:
Phytotherapy research 2019 v.33 no.9 pp. 2387-2400
ISSN:
0951-418X
Subject:
Candida albicans; Candida tropicalis; Escherichia coli; Phlomis fruticosa; Pseudomonas aeruginosa; Staphylococcus aureus; antimicrobial properties; beverages; biomarkers; colitis; colon; essential oils; fungi; lactate dehydrogenase; leaf extracts; lipopolysaccharides; malondialdehyde; nitrites; protective effect; rats; serotonin; signs and symptoms (animals and humans)
Abstract:
... Phlomis fruticosa L. and P. herba‐venti are species belonging to the Lamiaceae family, which have been traditionally used to prepare tonic and digestive drinks. Multiple studies also demonstrated the inhibitory effects of P. fruticosa extracts and essential oil against oxidative/proinflammatory pathways and bacterial strains deeply involved in ulcerative colitis. Considering these findings, the pr ...
DOI:
10.1002/ptr.6429

90. Recent progress on porcine circovirus type 3

Author:
Ouyang, Ting; Niu, Guyu; Liu, Xiaohua; Zhang, Xinwei; Zhang, Ying; Ren, Linzhu
Source:
Infection, genetics, and evolution 2019 v.73 pp. 227-233
ISSN:
1567-1348
Subject:
Porcine circovirus; Porcine circovirus-3; dermatitis; epidemiology; humans; inflammation; kidney diseases; pathogenesis; pathogens; pork industry; signs and symptoms (animals and humans); swine; ticks; tissues; viruses; wild boars; United States
Abstract:
... Porcine circovirus 3 (PCV3) is a newly identified virus that belongs to the genus Circovirus in the family Circoviridae. Since the first identification of PCV3 in domestic swine in 2016 in the USA, exciting progress on PCV3 has emphasized the importance of the virus. The aim of this review is to present recent advances in the molecular characteristics, epidemiology, and pathogenesis of PCV3. The v ...
DOI:
10.1016/j.meegid.2019.05.009

91. The first isolation and identification of canine parvovirus (CPV) type 2c variants during 2016–2018 genetic surveillance of dogs in Mongolia

Author:
Temuujin, Uyangaa; Tserendorj, Ariunaa; Fujiki, Jumpei; Sakoda, Yoshihiro; Tseren-Ochir, Erdene-Ochir; Okamatsu, Masatoshi; Matsuno, Keita; Sharav, Tumenjargal; Horiuchi, Motohiro; Umemura, Takashi; Chultemdorj, Tungalag
Source:
Infection, genetics, and evolution 2019 v.73 pp. 269-275
ISSN:
1567-1348
Subject:
Carnivore protoparvovirus 1; amino acid sequences; antigen detection; dogs; feces; fluorescent antibody technique; genetic variation; genome; hemorrhagic enteritis; high-throughput nucleotide sequencing; monitoring; mutation; myocarditis; phylogeny; polymerase chain reaction; signs and symptoms (animals and humans); China; Mongolia
Abstract:
... Canine parvovirus type 2 (CPV-2) causes a highly contagious and fatal disease, developing into acute hemorrhagic enteritis and myocarditis, in dogs. CPV-2 has evolved, generating antigenic variants CPV-2a/2b/2c that are globally distributed. However, investigating molecular characterization of CPV-2 among dog populations in Mongolia has been limited. Herein, 42 stool samples were collected from do ...
DOI:
10.1016/j.meegid.2019.05.006

92. The novel caprine parainfluenza virus type 3 showed pathogenicity in Guinea pigs

Author:
Hao, Fei; Wang, Zhongyu; Mao, Li; Yang, Leilei; Zhang, Wenwen; Li, Jizong; Wang, Xuyuan; Li, Wenliang; Jiang, Jieyuan
Source:
Microbial pathogenesis 2019 v.134 pp. 103569
ISSN:
0882-4010
Subject:
animal models; dead animals; goats; guinea pigs; hemagglutination; immunohistochemistry; laboratory animals; lungs; macrophages; necropsy; neutralizing antibodies; pathogenicity; pulmonary emphysema; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); staining; viral load; viremia; viruses
Abstract:
... Caprine parainfluenza virus type 3 (CPIV3) is one of the important viral respiratory tract agents in goats. The pathogenicity of CPIV3 has been examined in goats but it has not been explored in other laboratory animals. In the present study, an experimental infection of guinea pigs with CPIV3 was performed. The virus-inoculated guinea pigs displayed clinical signs related to the respiratory diseas ...
DOI:
10.1016/j.micpath.2019.103569

93. Transcriptomic response of rainbow trout (Oncorhynchus mykiss) skeletal muscle to Flavobacterium psychrophilum

Author:
Rivas-Aravena, Andrea; Fuentes-Valenzuela, Marcia; Escobar-Aguirre, Sebastian; Gallardo-Escarate, Cristian; Molina, Alfredo; Valdés, Juan Antonio
Source:
Comparative biochemistry and physiology 2019 v.31 pp. 100596
ISSN:
1744-117X
Subject:
Flavobacterium psychrophilum; Oncorhynchus mykiss; apoptosis; aquaculture industry; bacterial cold-water disease; caspases; creatine kinase; cytotoxicity; enzyme activity; freshwater; high-throughput nucleotide sequencing; muscle contraction; muscular atrophy; myoblasts; myositis; pathogenesis; pathogens; proteolysis; signs and symptoms (animals and humans); skeletal muscle; transcriptomics; ubiquitin
Abstract:
... Flavobacterium psychrophilum is the etiologic agent of rainbow trout fry syndrome (RTFS). This pathogen infects a wide variety of salmonid species during freshwater stages, causing significant losses in the aquaculture industry. Rainbow trout (Oncorhynchus mykiss) infected with F. psychrophilum, presents as the main external clinical sign ulcerative lesions and necrotic myositis in skeletal muscle ...
DOI:
10.1016/j.cbd.2019.100596

94. Viral agents of gastroenteritis and their correlation with clinical symptoms in rotavirus-vaccinated children

Author:
Quintero-Ochoa, Guadalupe; Romero-Argüelles, Ricardo; Aviles-Hernández, Armando; Cejudo-Flores, Michel; Calleja-García, Patricia; Domínguez-Gámez, Maribel; Cantú-Bernal, Servando; Icedo-García, Ramona; Soñanez-Organis, José; Rosas-Rodríguez, Jesús; Romo-Saenz, César; Tamez-Guerra, Patricia; Flores-Mendoza, Lilian; González-Ochoa, Guadalupe
Source:
Infection, genetics, and evolution 2019 v.73 pp. 190-196
ISSN:
1567-1348
Subject:
Astroviridae; Mastadenovirus; Norovirus; Rotavirus; Sapovirus; children; diarrhea; disease severity; gastroenteritis; genotype; genotyping; reverse transcriptase polymerase chain reaction; signs and symptoms (animals and humans); vaccination; vaccines; Mexico
Abstract:
... Enteric viral infections are among the leading causes of gastroenteritis in children up to five years of age worldwide. This study was aimed to determine the disease severity, incidence, and molecular genotyping of rotaviruses, noroviruses, astroviruses, and enteric adenoviruses as gastroenteritis agents among children up to five years old.Gastroenteritis severity was determined by using the Ruusk ...
DOI:
10.1016/j.meegid.2019.05.002

95. A vaccine based on recombinant modified Vaccinia Ankara containing the nucleoprotein from Lassa virus protects against disease progression in a guinea pig model

Author:
Kennedy, E.M.; Dowall, S.D.; Salguero, F.J.; Yeates, P.; Aram, M.; Hewson, R.
Source:
Vaccine 2019 v.37 no.36 pp. 5404-5413
ISSN:
0264-410X
Subject:
nucleoproteins; disease progression; T-lymphocytes; vaccines; Lassa mammarenavirus; Lassa virus fever; secondary immunization; signs and symptoms (animals and humans); weight loss; enzyme-linked immunosorbent assay; mice; animal models; immunogenicity; immune response; vaccination; guinea pigs; virulence; fever; Europe; Western Africa
Abstract:
... Lassa fever remains the most imported viral haemorrhagic fever in Europe and is responsible for 5000 deaths per year throughout Western Africa. There is no vaccine and treatment is often ineffective. We have developed a vaccine based on modified Vaccinia Ankara expressing the nucleoprotein from Lassa virus (MVALassaNP). This study investigated the immunogenicity (in mice) and efficacy (in guinea p ...
DOI:
10.1016/j.vaccine.2019.07.023

96. Gluten and FODMAPS—Sense of a Restriction/When Is Restriction Necessary?

Author:
Dieterich, Walburga; Zopf, Yurdagül
Source:
Nutrients 2019 v.11 no.8
ISSN:
2072-6643
Subject:
amylases; celiac disease; fructans; gluten; gluten-free diet; gluten-free foods; intestinal microorganisms; intestinal mucosa; irritable bowel syndrome; minerals; monosaccharides; nutrient deficiencies; oligosaccharides; patients; polyols; signs and symptoms (animals and humans); therapeutics; trypsin inhibitors; vitamins; wheat
Abstract:
... Gluten-free diet (GFD) is enjoying increasingly popularity, although gluten-free products are considerably more expensive. GFD is absolutely necessary for patients with celiac disease, as in this case even minor amounts of gluten can lead to the destruction of the intestinal mucosa. In addition, GFD is currently the best therapy to improve clinical symptoms of patients with non-celiac gluten sensi ...
DOI:
10.3390/nu11081957

97. Identification of six novel mutations in five infants with suspected maple syrup urine disease based on blood and urine metabolism screening

Author:
Yang, Chenxi; Linpeng, Siyuan; Cao, Yingxi; Wu, Lingqian
Source:
Gene 2019 v.710 pp. 9-16
ISSN:
0378-1119
Subject:
bioinformatics; blood; early diagnosis; genetic analysis; high-throughput nucleotide sequencing; infants; lactic acid; leucine; maple syrup urine disease; metabolism; models; mutation; pathogenicity; patients; phenotype; screening; signs and symptoms (animals and humans); urine; valine
Abstract:
... Maple syrup urine disease (MSUD) is a rare autosomal recessive genetic metabolic disease, with a high incidence rate in infants. We analyzed the data of molecular genetic analysis of five infants whose metabolism screening suspected MSUD and described their clinical symptoms. Further, we performed next-generation sequencing and Sanger sequencing to determine the genetic causes of the disease. Bioi ...
DOI:
10.1016/j.gene.2019.04.086

98. Modelling the immunopathophysiology of Brucella melitensis and its lipopolysaccharide in mice infected via oral route of exposure

Author:
Osman, Abdinasir Yusuf; Kadir, Arifah Abdul; Jesse, Faez Firdaus; Saharee, Abdul Aziz
Source:
Microbial pathogenesis 2019
ISSN:
0882-4010
Subject:
Brucella melitensis; animal models; antibodies; estradiol; exposure pathways; gastrointestinal system; gender; histopathology; immunoglobulin G; immunoglobulin M; interleukin-1beta; interleukin-6; lipopolysaccharides; livestock and meat industry; mice; oral administration; pathogenesis; pathogens; phosphates; progesterone; signs and symptoms (animals and humans); testosterone; tissues; virulence
Abstract:
... Brucella melitensis is one of the leading zoonotic pathogens with significant economic implications in animal industry worldwide. Lipopolysaccharide, however, is by far the major virulence with substantial role in the process of diseases pathogenesis. Nonetheless, the effect of B. melitensis and its lipopolysaccharide on immunopathophysiological aspects largely remains an enigma. This study examin ...
DOI:
10.1016/j.micpath.2019.103669

99. Parasite control in organic cattle farming: Management and farmers' perspectives from six European countries

Author:
Takeuchi-Storm, Nao; Moakes, Simon; Thüer, Susann; Grovermann, Christian; Verwer, Cynthia; Verkaik, Jan; Knubben-Schweizer, Gabriela; Höglund, Johan; Petkevicius, Saulius; Thamsborg, Stig; Werne, Steffen
Source:
Veterinary Parasitology: Regional Studies and Reports 2019
ISSN:
2405-9390
Subject:
European Union; anthelmintics; antibody detection; bulk milk; cattle; control methods; dairy farming; diarrhea; farmers; farmers' attitudes; farms; fecal egg count; gastrointestinal parasites; gastrointestinal system; grazing; labor; liver; liver flukes; livestock and meat industry; models; monitoring; organic foods; organic production; pastures; signs and symptoms (animals and humans); surveys; Denmark; Germany; Lithuania; Netherlands; Sweden; Switzerland
Abstract:
... Organic ruminant production is expanding in the EU, but parasite management remains a constant challenge. Mandatory outdoor access for all age groups can increase exposure to pasture borne parasites, whilst restrictions in the prophylactic use of anthelmintics can limit parasite control. The scientific community has been working to deliver effective parasite control strategies and alternative appr ...
DOI:
10.1016/j.vprsr.2019.100329

100. Health Benefits of <i>Lactobacillus gasseri</i> CP2305 Tablets in Young Adults Exposed to Chronic Stress: A Randomized, Double-Blind, Placebo-Controlled Study

Author:
Nishida, Kensei; Sawada, Daisuke; Kuwano, Yuki; Tanaka, Hiroki; Rokutan, Kazuhito
Source:
Nutrients 2019 v.11 no.8
ISSN:
2072-6643
Subject:
Bifidobacterium; Lactobacillus gasseri; Streptococcus; anxiety; electroencephalography; feces; heat inactivation; intestinal microorganisms; inventories; irritable bowel syndrome; men; patients; physicians; placebos; ribosomal RNA; sequence analysis; signs and symptoms (animals and humans); sleep deprivation; students; women; young adults
Abstract:
... Short-term administration of Lactobacillus gasseri CP2305 improves stress-associated symptoms and clinical symptoms in healthy young adults and in patients with irritable bowel syndrome, respectively. We evaluated the efficacy and health benefits of the long-term use of a tablet containing heat-inactivated, washed Lactobacillus gasseri CP2305 (CP2305) in healthy young adults. Sixty Japanese medica ...
DOI:
10.3390/nu11081859