Jump to Main Content
- Estellé, Jordi, et al. Show all 8 Authors
- Genetics, selection, evolution 2015 v.47 no.1 pp. 111
- 3' untranslated regions; adipose tissue; alleles; backfat; bacterial artificial chromosomes; binding sites; clones; epigenetics; estrogen receptors; exons; fatty acid composition; gene expression; high-throughput nucleotide sequencing; landraces; linkage disequilibrium; liver; longissimus muscle; major genes; meat quality; methylation; palmitoleic acid; promoter regions; quantitative trait loci; single nucleotide polymorphism; swine
- ... BACKGROUND: In previous studies on an Iberian x Landrace cross, we have provided evidence that supported the porcine ELOVL6 gene as the major causative gene of the QTL on pig chromosome 8 for palmitic and palmitoleic acid contents in muscle and backfat. The single nucleotide polymorphism (SNP) ELOVL6:c.-533C > T located in the promoter region of ELOVL6 was found to be highly associated with ELOVL6 ...
- PubMed Central:
- Estellé, Jordi, et al. Show all 12 Authors
- Mammalian genome 2011 v.22 no.9-10 pp. 602-612
- Sus scrofa; animal models; genes; humans; loci; melanocytes; melanoma; microsatellite repeats; quantitative trait loci; single nucleotide polymorphism; swine; transcription (genetics); transcription factors; ultraviolet radiation
- ... Cutaneous melanoma arises from transformed melanocytes and is caused mainly by environmental effects such as ultraviolet radiation and to a lesser extent by predisposing genetic variants. Only a few susceptibility genes for cutaneous melanoma have been identified so far in human; therefore, animal models represent a valuable alternative for genetic studies of this disease. In a previous quantitati ...
- Estellé, Jordi, et al. Show all 15 Authors
- Animalia; antigens; data collection; gene expression; humans; immunity; infectious diseases; leukocytes; major histocompatibility complex; microRNA; phenotypic variation; prediction; single nucleotide polymorphism; swine; swine production; vaccines
- ... The SLA (swine leukocyte antigen, MHC: SLA) genes are the most important determinants of immune, infectious disease and vaccine response in pigs; several genetic associations with immunity and swine production traits have been reported. However, most of the current knowledge on SLA is limited to gene coding regions. MicroRNAs (miRNAs) are small molecules that post-transcriptionally regulate the ex ...
- PubMed Central: