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1. (U,Th)-He dating of Pleistocene carbonates: Analytical methods and age calculations

Author:
Jan D. Kramers; Tebogo V. Makhubela
Source:
MethodsX 2022 v.9 pp. 101608
ISSN:
2215-0161
Subject:
Pleistocene epoch; calcium carbonate; evolution; foil; furnaces; helium; isotopes; mass spectrometry; paleoclimatology; spectrometers
Abstract:
... The uranium-thorium-helium ((U,Th)-He) dating method applied to calcium carbonate speleothems holds much promise for constraining the timeline of hominin evolution, as well as for palaeoclimatology research beyond the range of U/Th disequilibrium dating. Technical problems are posed by often low U concentrations and the requirement that samples need to be individually removed from the ultrahigh va ...
DOI:
10.1016/j.mex.2021.101608

2. (−)ESI/CAD MSn Procedure for Sequencing Lignin Oligomers Based on a Study of Synthetic Model Compounds with β-O-4 and 5-5 Linkages

Author:
Huaming Sheng; Weijuan Tang; Jinshan Gao; James S. Riedeman; Guannan Li; Tiffany M. Jarrell; Matthew R. Hurt; Linan Yang; Priya Murria; Xin Ma; John J. Nash; Hilkka I. Kenttämaa
Source:
Analytical chemistry 2017 v.89 no.24 pp. 13089-13096
ISSN:
1520-6882
Subject:
aromatic compounds; dissociation; elemental composition; formaldehyde; ions; lignin; models; spectrometers
Abstract:
... Seven synthesized G-lignin oligomer model compounds (ranging in size from dimers to an octamer) with 5-5 and/or β-O-4 linkages, and three synthesized S-lignin model compounds (a dimer, trimer, and tetramer) with β-O-4 linkages, were evaporated and deprotonated using negative-ion mode ESI in a linear quadrupole ion trap/Fourier transform ion cyclotron resonance mass spectrometer. The collision-acti ...
DOI:
10.1021/acs.analchem.7b01911

3. 1,6-Diphenyl-1,3,5-hexatriene (DPH) as a Novel Matrix for MALDI MS Imaging of Fatty Acids, Phospholipids, and Sulfatides in Brain Tissues

Author:
Ibrahim Hanadi; Jurcic Kristina; Wang Jasmine S.-H.; Whitehead Shawn N.; Yeung Ken K.-C.
Source:
Analytical chemistry 2017 v.89 no.23 pp. 12828-12836
ISSN:
1520-6882
Subject:
brain; desorption; energy; fatty acids; fluorescent dyes; image analysis; mass spectrometry; mice; phosphatidylserines; rats; spectrometers; sublimation; tissues
Abstract:
... 1,6-Diphenyl-1,3,5-hexatriene (DPH) is a commonly used fluorescence probe for studying cell membrane-lipids due to its affinity toward the acyl chains in the phospholipid bilayers. In this work, we investigated its use in matrix-assisted laser desorption/ionization (MALDI) as a new matrix for mass spectrometry imaging (MSI) of mouse and rat brain tissue. DPH exhibits very minimal matrix-induced ba ...
DOI:
10.1021/acs.analchem.7b03284

4. 10-GHz Self-Referenced Optical Frequency Comb

Author:
Bartels, Albrecht; Heinecke, Dirk; Diddams, Scott A.
Source:
Science 2009 v.326 no.5953 pp. 681
ISSN:
0036-8075
Subject:
metrology; spectrometers; spectroscopy; ticks
Abstract:
... The femtosecond laser-based frequency comb has played a key role in high-precision optical frequency metrology for a decade. Although often referred to as a precise optical frequency ruler, its tick marks are in fact too densely spaced for direct observation and individual use, limiting important applications in spectroscopy, astronomy, and ultrafast electromagnetic waveform control. We report on ...
DOI:
10.1126/science.1179112

5. 10Be depositional flux variation in the central Indian Ocean during the last 43 ka

Author:
Partha Sarathi Jena; Ravi Bhushan; Shivam Ajay; Nisha Bharti; A.K. Sudheer
Source:
Science of the total environment 2022 v.802 pp. 149808
ISSN:
0048-9697
Subject:
Holocene epoch; carbon radioisotopes; data collection; environment; half life; magnetic fields; marine sediments; sediment deposition; spectrometers; temporal variation; Indian Ocean
Abstract:
... The advent of Accelerator Mass Spectrometer (AMS) enhanced the application of meteoric ¹⁰Be (half-life of 1.39 Ma) as a tracer for understanding earth surface processes on thousand to million-year time scales. However, for the majority of applications, an adequate understanding of the ¹⁰Be depositional flux is a prerequisite. A number of efforts have been made to understand both spatial and tempor ...
DOI:
10.1016/j.scitotenv.2021.149808

6. 10years of MS instrumental developments – Impact on LC–MS/MS in clinical chemistry

Author:
Markus Himmelsbach
Source:
Journal of chromatography 2012 v.883-884 no. pp. 3-17
ISSN:
1570-0232
Subject:
atmospheric pressure; biochemistry; chemistry; liquid chromatography; medicine; spectrometers; tandem mass spectrometry
Abstract:
... The combination of liquid chromatography and mass spectrometry (LC–MS) is a powerful and indispensable analytical tool that is widely applied in many areas of chemistry, medicine, pharmaceutics and biochemistry. In this review recent MS instrumental developments are presented as part of a special issue covering various aspects of liquid chromatography tandem mass spectrometry (LC–MS/MS) in clinica ...
DOI:
10.1016/j.jchromb.2011.11.038

7. 12-Deoxyroridin J and 12-Deoxyepiisororidin E from Calcarisporium arbuscular

Author:
Manami Matsumoto; Shizuya Tanaka; Akio Tonouchi; Masaru Hashimoto
Source:
Tetrahedron letters 2018 v.59 no.21 pp. 1992-1995
ISSN:
0040-4039
Subject:
biochemical pathways; biosynthesis; chemical reactions; chemical structure; circular dichroism spectroscopy; culture media; density functional theory; nuclear magnetic resonance spectroscopy; roridins; spectrometers; wavelengths
Abstract:
... The culture broth of Calcarisporium arbuscular afforded 12-deoxyroridin J (1) and 12-deoxyepiisororidin E (2). Their structures were elucidated based on NMR and ECD analyses. Both molecules showed negative ECD splitting at 240 nm and a negative Cotton effect at 200 nm. Density functional theory calculations revealed that the former is caused due to the ECD exciton coupling between the C1′–C3′ enon ...
DOI:
10.1016/j.tetlet.2018.03.089

8. 13C metabolic flux analysis of the extremely thermophilic, fast growing, xylose-utilizing Geobacillus strain LC300

Author:
Lauren T. Cordova; Maciek R. Antoniewicz
Source:
Metabolic engineering 2016 v.33 pp. 148-157
ISSN:
1096-7176
Subject:
Geobacillus; NADP (coenzyme); amino acids; biomass; biotechnology; carbon; carbon dioxide; energy flow; feedstocks; gas chromatography-mass spectrometry; genome; glycolysis; hosts; industry; isotope labeling; metabolic engineering; metabolic flux analysis; models; pentose phosphate cycle; spectrometers; temperature; thermophilic microorganisms; tricarboxylic acid cycle; xylose
Abstract:
... Thermophiles are increasingly used as versatile hosts in the biotechnology industry. One of the key advantages of thermophiles is the potential to achieve high rates of feedstock conversion at elevated temperatures. The recently isolated Geobacillus strain LC300 grows extremely fast on xylose, with a doubling time of less than 30min. In the accompanying paper, the genome of Geobacillus LC300 was s ...
DOI:
10.1016/j.ymben.2015.06.004

9. 18O2 label mechanism of sulfur generation and characterization in properties over mesoporous Sm-based sorbents for hot coal gas desulfurization

Author:
B.S. Liu; Z.Y. Wan; F. Wang; Y.P. Zhan; M. Tian; A.S.C. Cheung
Source:
Journal of hazardous materials 2014 v.267 pp. 229-237
ISSN:
0304-3894
Subject:
X-ray diffraction; adsorbents; chemical industry; coal; cobalt; desulfurization; hydrogen sulfide; iron; mass spectrometry; porous media; samarium; sol-gel processing; spectrometers; sulfur; temperature; thermogravimetry; transmission electron microscopy; zinc
Abstract:
... Using a sol–gel method, SmMeOx/MCM-41 or SBA-15 (Me=Fe, Co and Zn) and corresponding unsupported sorbents were prepared. The desulfurization performance of these sorbents was evaluated over a fixed-bed reactor and the effects of reaction temperature, feed and sorbent composition on desulfurization performance were studied. Samarium-based sorbents used to remove H2S from hot coal gas were reported ...
DOI:
10.1016/j.jhazmat.2013.12.065

10. 195 Lipid profiling of bovine oocytes matured with different stimulation of cyclic GMP synthesis by multiple reaction monitoring profiling

Author:
L. Schefer; L. M. Naves; C. Ramires Ferreira; E. Pradebon da Silva; T. J. Sobreira; P. Vieiro Marchioretto; C. L. V. Leal; M. Rubessa; M. B. Wheeler
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 226
ISSN:
1031-3613
Subject:
analysis of variance; blood serum; cattle; cryopreservation; cyclic GMP; energy; enzymes; follicle-stimulating hormone; gentamicin; glutamine; lipid composition; lipid metabolism; luteinizing hormone; monitoring; oocytes; phosphatidylcholines; phosphatidylethanolamines; phosphatidylserines; principal component analysis; protoporphyrin; spectrometers; sphingomyelins; triacylglycerols
Abstract:
... Intrafollicular lipid metabolism is very important for production species such as cattle. Lipids are essential substrates to produce energy during growth, maturation, and acquisition of high competence for the development of oocytes. However, the quantity and distribution of these lipids has been identified as responsible for hindering the process of cryopreservation of oocytes and embryos produce ...
DOI:
10.1071/RDv32n2Ab195

11. 1H NMR-based metabolomics of antimalarial plant species traditionally used by Vha-Venda people in Limpopo Province, South Africa and isolation of antiplasmodial compounds

Author:
M. Johanna Bapela; Heino Heyman; Francois Senejoux; J.J. Marion Meyer
Source:
Journal of ethnopharmacology 2019 v.228 pp. 148-155
ISSN:
0378-8741
Subject:
Tabernaemontana; antimalarials; antiplasmodial properties; chemical constituents of plants; chromatography; indigenous species; indole alkaloids; inhibitory concentration 50; lipophilicity; malaria; medicinal plants; metabolomics; methylene chloride; multivariate analysis; nuclear magnetic resonance spectroscopy; people; principal component analysis; rural areas; spectrometers; traditional medicine; South Africa
Abstract:
... The Vha-Venda people living in rural areas of Limpopo Province of South Africa regularly use traditional plant-based medicines to treat malaria. In our earlier publication, twenty indigenous plant species used to treat malaria or its symptoms by Vha-Venda people were evaluated for antiplasmodial activity. The main objective of the current study was to assess the robustness of NMR-based metabolomic ...
DOI:
10.1016/j.jep.2018.07.022

12. 1H qNMR Quantification of Annonaceous Acetogenins in Crude Extracts of Annona muricata L. Fruit Pulp

Author:
Natacha Bonneau; Timothé Cynober; Jean‐Christophe Jullian; Pierre Champy
Source:
Phytochemical analysis 2017 v.28 no.4 pp. 251-256
ISSN:
0958-0344
Subject:
Annona muricata; Parkinson disease; acetogenins; chemical constituents of plants; chloroform; dementia; detection limit; dimethyl fumarate; edible fruits; food safety; foods; fruit pulp; fumaric acid; humans; methanol; neurotoxins; nuclear magnetic resonance spectroscopy; protons; spectrometers
Abstract:
... INTRODUCTION: Annonaceous acetogenins (AAGs) constitute a group of environmental neurotoxins, possibly implicated in sporadic atypical Parkinsonism/dementia complexes. The recent evidencing of complex mixtures of AAGs in edible fruits and derived food products requires efficient and practical analytical tools for an estimation of human exposure. OBJECTIVE: To develop a simple method for the direct ...
DOI:
10.1002/pca.2668

13. 1H/13C chemical shifts and cation binding dataset of the corticosteroid Prednisolone titrated with metal cations

Author:
Kathleen Joyce D. Carillo; Danni Wu; Su-Ching Lin; Shen-Long Tsai; Jiun-Jie Shie; Der-Lii M. Tzou
Source:
Data in Brief 2019 v.27 pp. 104620
ISSN:
2352-3409
Subject:
Gibbs free energy; adrenal cortex hormones; calcium; cations; computer software; data collection; magnesium; nuclear magnetic resonance spectroscopy; prednisolone; spectrometers
Abstract:
... We here reported the ¹H/¹³C chemical shifts, binding affinity and binding free energy of 1,4-pregnadiene-11β,17α,21-triol-3,20-dione (Prednisolone; Prd) interacting with metal cations. Six different Prd/Ni or Co mixtures were examined at different molar ratios (1:0, 1:0.1, 1:0.2, 1:0.3, 1:0.4 and 1:0.5). In this analysis, the ¹H and ¹³C chemical shifts were measured for the Prd/cation mixtures usi ...
DOI:
10.1016/j.dib.2019.104620

14. 2,5‐Dihydroxybenzoic acid solution in MALDI‐MS: ageing and use for mass calibration

Author:
Anu Teearu; Signe Vahur; Uku Haljasorg; Ivo Leito; Tõiv Haljasorg; Lauri Toom
Source:
Journal of mass spectrometry 2014 v.49 no.10 pp. 970-979
ISSN:
1076-5174
Subject:
2,5-dihydroxybenzoic acid; Fourier transform infrared spectroscopy; acetonitrile; chemical degradation; matrix-assisted laser desorption-ionization mass spectrometry; spectral analysis; spectrometers
Abstract:
... 2,5‐Dihydroxybenzoic acid (DHB) is one of the most widely used and studied matrix compounds in matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry. However, the influence of ageing of the DHB solution on the MALDI mass spectra has not been yet systematically studied. In this work, the possible changes occurring in the acidified acetonitrile/water solution of the MALDI matrix comp ...
DOI:
10.1002/jms.3395

15. 2014 iAREA campaign on aerosol in Spitsbergen – Part 1: Study of physical and chemical properties

Author:
J. Lisok; K.M. Markowicz; C. Ritter; P. Makuch; T. Petelski; M. Chilinski; J.W. Kaminski; S. Becagli; R. Traversi; R. Udisti; A. Rozwadowska; M. Jefimow; P. Markuszewski; R. Neuber; P. Pakszys; I.S. Stachlewska; J. Struzewska; T. Zielinski
Source:
Atmospheric environment 2016 v.140 pp. 150-166
ISSN:
1352-2310
Subject:
absorption; aerosols; atmospheric chemistry; carbon; combustion; emissions; governmental programs and projects; mathematical models; particulates; remote sensing; spectrometers; spring; sulfates; temporal variation; traffic; wind speed; Norway
Abstract:
... This paper presents the results of measurements of aerosol physical and chemical properties during iAREA2014 campaign that took place on Svalbard between 15th of Mar and 4th of May 2014. With respect to field area, the experiment consisted of two sites: Ny–Ålesund (78°55′N, 11°56′E) and Longyearbyen (78°13′N, 15°33′E) with further integration of Aerosol Robotic Network (AERONET) station in Hornsun ...
DOI:
10.1016/j.atmosenv.2016.05.051

16. 21 Tesla FT-ICR Mass Spectrometer for Ultrahigh-Resolution Analysis of Complex Organic Mixtures

Author:
Donald F. Smith; David C. Podgorski; Ryan P. Rodgers; Greg T. Blakney; Christopher L. Hendrickson
Source:
Analytical chemistry 2018 v.90 no.3 pp. 2041-2047
ISSN:
1520-6882
Subject:
bitumen; dissolved organic matter; elemental composition; mass spectrometry; petroleum; spectrometers
Abstract:
... We describe complex organic mixture analysis by 21 tesla (T) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Ultrahigh mass-resolving power (m/Δm₅₀% > 2 700 000 at m/z 400) and mass accuracy (80 ppb rms) enable resolution and confident identification of tens of thousands of unique elemental compositions. We demonstrate 2.2-fold higher mass-resolving power, 2.6-fold better ...
DOI:
10.1021/acs.analchem.7b04159

17. 210-Polonium studies in some environmental and biological matrices of Domiasiat uranium deposit area, West Khasi Hills, Meghalaya, India

Author:
Marbaniang, Deswyn G.; Poddar, Raj K.; Nongkynrih, Phlis; Khathing, Darlando T.
Source:
Environmental monitoring and assessment 2010 v.162 no.1-4 pp. 347-353
ISSN:
0167-6369
Subject:
Garra; Macrobrachium; World Health Organization; adults; fish; ingestion; meat; polonium; radionuclides; silicon; soil; spectrometers; uranium; India
Abstract:
... The study was performed using a silicon surface barrier alpha spectrometer at Bhabha Atomic Research Centre, Mumbai, India. Through the study, the observed ²¹⁰Po activity in water sample from different locations in the Domiasiat area ranges from 0.04 to 0.69 Bq/l. The daily and annual intake of ²¹⁰Po through water was also estimated and the mean value of 0.72 and 263.61 Bq, respectively, were obse ...
DOI:
10.1007/s10661-009-0800-5
PubMed:
19242810

18. 234U, 238U, 226Ra, 228Ra and 40K concentrations in feed coal and its combustion products during technological processes in the Upper Silesian Industrial Region, Poland

Author:
A. Walencik-Łata; D. Smołka-Danielowska
Source:
Environmental pollution 2020 v.267 pp. 115462
ISSN:
0269-7491
Subject:
biomass; bottom ash; coal; combustion; energy; fluidized beds; fly ash; furnaces; gamma spectrometry; pollution; radioactivity; silt; spectrometers; Poland
Abstract:
... Hard coal is the predominant energy source in Poland. The unavoidable consequence of coal combustion is the production of huge amounts of ash which can be concentrated in radionuclides. The ashes from coal combustion are utilized or stored and may affect the quality of the environment. Therefore, the estimation of radionuclides in hard coal and by-products is of crucial importance. The analyzed sa ...
DOI:
10.1016/j.envpol.2020.115462

19. 2D LC as a tool for standardization of Foenugraeci semen extracts containing compounds with anti-Helicobacter pylori activity

Author:
Barbara Król-Kogus; Daniel Głód; Rafał Hałasa; Mirosława Krauze-Baranowska; Loretta Pobłocka-Olech
Source:
Food & function 2021 v.12 no.6 pp. 2686-2692
ISSN:
2042-650X
Subject:
Helicobacter pylori; Trigonella foenum-graecum; antibacterial properties; bacteria; diodes; diosgenin; fenugreek; liquid chromatography; methanol; semen; separation; spectrometers; standardization
Abstract:
... The on-line heart-cutting two-dimensional liquid chromatography method with the use of a diode array detector and a mass spectrometer (LC-LC-DAD-ESI-MS) was established and validated for quantitation of C-glycosylflavones in fenugreek seeds (Foenugraeci semen, Trigonella foenum-graecum L.). The first- (¹D) and second- (²D) dimensional separations were performed on Kinetex C-18 columns with differe ...
DOI:
10.1039/d1fo00226k

20. 3D Bombax-structured carbon nanotube sponge coupling with Ag3PO4 for tetracycline degradation under ultrasound and visible light irradiation

Author:
Jiafeng Jin; Min Liu; Lanhui Feng; Haoyu Wang; Yanling Wang; Tuan A.H. Nguyen; Yameng Wang; Jinren Lu; Yiming Li; Mutai Bao
Source:
Science of the total environment 2019 v.695 pp. 133694
ISSN:
0048-9697
Subject:
adsorption; carbon nanotubes; electrochemistry; electron paramagnetic resonance spectroscopy; free radicals; gas chromatography-mass spectrometry; ion exchange; irradiation; moieties; photocatalysis; photoluminescence; photolysis; spectrometers; surface area; tetracycline; ultrasonic treatment; ultrasonics; vapors
Abstract:
... A novel photocatalytic carbon nanotube sponge with three-dimensional Bombax-structure was fabricated by a facile chemical vapor deposition followed by in situ ion-exchange approach. The as-prepared sponge achieved both high-efficiency adsorption and photocatalysis towards antibiotics, which can remove up to 90% of tetracycline within an hour. The morphology and mechanism of the photocatalytic CNT ...
DOI:
10.1016/j.scitotenv.2019.133694

21. 3D Printing for Low-Cost and Versatile Attenuated Total Reflection Infrared Spectroscopy

Author:
Bettina Baumgartner; Stephan Freitag; Bernhard Lendl
Source:
Analytical chemistry 2020 v.92 no.7 pp. 4736-4741
ISSN:
1520-6882
Subject:
Escherichia coli; Fourier transform infrared spectroscopy; bovine serum albumin; cost effectiveness; crystals; epoxides; germanium; optical equipment; polymerization; silicon; spectrometers; temperature; three-dimensional printing; wafers
Abstract:
... In this work, we present a fully 3D-printed module for attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy ready for use in commercial FTIR spectrometers. The developed setup stands out in terms of robustness and ease of sample application. Rapid prototyping paired with theoretical considerations were employed to design and fabricate the module. Cost-efficient commercial ...
DOI:
10.1021/acs.analchem.9b04043

22. 3D SERS (surface enhanced Raman scattering) imaging of intracellular pathways

Author:
Kai-Chih Huang; Kazuki Bando; Jun Ando; Nicholas I. Smith; Katsumasa Fujita; Satoshi Kawata
Source:
Methods 2014 v.68 pp. 348-353
ISSN:
1046-2023
Subject:
Raman spectroscopy; image analysis; microscopy; nanogold; space and time; spectrometers
Abstract:
... We demonstrate dynamic surface-enhanced Raman scattering (SERS) imaging with 3 dimensional mapping in a living cell by combining a confocal Raman spectrometer and dual-focus dark-field microscopy. Gold nanoparticles acting as a probe traveling through the living cell, are tracked by dual-focus dark-field imaging, with position feedback to the confocal Raman spectrometer in order to record evolving ...
DOI:
10.1016/j.ymeth.2014.02.007

23. 3D spectral analysis in the VNIR–SWIR spectral region as a tool for soil classification

Author:
Yaron Ogen; Naftaly Goldshleger; Eyal Ben-Dor
Source:
Geoderma 2017 pp. -
ISSN:
0016-7061
Subject:
air drying; algorithms; clay fraction; soil classification; soil horizons; soil profiles; soil sampling; soil surveys; soil types; spatial data; spectral analysis; spectrometers; spectroscopy
Abstract:
... Visible, near-infrared and shortwave-infrared (VNIR–SWIR) spectroscopy has proven to be an efficient, rapid and low-cost method for soil spectral analysis that can improve on the results obtained from today's traditional methods of conducting soil surveys. Nonetheless, this tool is used mostly in the laboratory and at surface level. The main objective of this paper is to develop a new optical meth ...
DOI:
10.1016/j.geoderma.2017.04.020

24. 4MBA-labeled Ag-nanorod aggregates coated with SiO₂: synthesis, SERS activity, and biosensing applications

Author:
Wei Lai; Jun Zhou; Yanting Liu; Zhenhong Jia; Shusen Xie; Lucia Petti; Pasquale Mormile
Source:
Analytical methods 2015 v.7 no.20 pp. 8832-8838
ISSN:
1759-9679
Subject:
Raman spectroscopy; antibodies; antigens; centrifugation; cetyltrimethylammonium bromide; detection limit; immunoassays; nanorods; nanosilver; optical properties; silica; spectrometers; surface plasmon resonance; surfactants; transmission electron microscopes; ultraviolet-visible spectroscopy
Abstract:
... A new nanostructure, silica-coated Ag nanorods (NRs) aggregate with 4-mercaptobenzoic acid molecules (4MBA-Ag NRs@SiO₂), was prepared by a seed-mediated growth method and a modified Stöber method. In the synthetic process, the optimal 4MBA-Ag NRs@SiO₂ was obtained by varying conditions such as surfactant concentration and centrifugation cycles. The morphologies and the optical properties of the 4M ...
DOI:
10.1039/c5ay01886b

25. 59 lipid dynamics in the early embryonic development of zebrafish by desorption electrospray ionization mass spectrometry imaging and nanoelectrospray–mass spectrometry

Author:
A. K. Jarmusch; C. T. Mahapatra; V. Pirro; C. R. Ferreira; M. S. Sepúlveda
Source:
Reproduction, fertility, and development 2016 v.28 no.2 pp. 159-160
ISSN:
1031-3613
Subject:
Danio rerio; acetonitrile; bile acids; cell membranes; cholesterol; cholesteryl esters; desorption; developmental stages; dimethylformamide; early development; electrospray ionization mass spectrometry; embryogenesis; image analysis; lipid content; lipid metabolism; mitochondria; nutrients; organogenesis; paper; phosphatidylcholines; phosphatidylglycerols; principal component analysis; silver nitrate; spectrometers; squalene; triacylglycerols; ubiquinones; yolk sac
Abstract:
... This study introduces a combination of mass spectrometry-based analytical approaches with little or no sample preparation for the study of zebrafish (Danio rerio) lipid metabolism during early development (0 through 96h post-fertilization, hpf). Desorption electrospray ionization mass spectrometry (DESI-MS) imaging and nanoelectrospray (nESI) MS were used. Embryos (N=107) were placed onto filter p ...
DOI:
10.1071/RDv28n2Ab58

26. 66 Lipid profiling of bovine blastocysts produced invitro with and without a stimulator of cyclic guanosine monophosphate synthesis by multiple reaction monitoring profiling

Author:
L. Schefer; L. M. Naves; C. Ramires Ferreira; E. Pradebon da Silva; T. J. Sobreira; P. Vieiro Marchioretto; C. Lima Verde Leal; M. Rubessa; M. B. Wheeler
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 158-159
ISSN:
1031-3613
Subject:
animal reproduction; blastocyst; blood serum; cGMP-dependent protein kinase; cattle; cryopreservation; culture media; cyclic AMP; cyclic GMP; cytoplasm; follicle-stimulating hormone; gentamicin; glutamine; lipid composition; lipid metabolism; luteinizing hormone; monitoring; oocytes; phosphatidylcholines; principal component analysis; spectrometers; spermatozoa; sphingomyelins; t-test; tissue culture; triacylglycerols
Abstract:
... Cryopreservation of oocytes and embryos is an essential technique for invitro-produced cattle worldwide. One of the great difficulties of cryopreservation of oocytes and blastocysts is the accumulation of lipids in the cytoplasm when produced invitro. The lipid metabolism of oocytes and embryos is classically regulated by the cAMP pathway. Furthermore, previous studies have suggested that the cycl ...
DOI:
10.1071/RDv32n2Ab66

27. 67P/Churyumov-Gerasimenko, a Jupiter family comet with a high D/H ratio

Author:
K. Altwegg; H. Balsiger; A. Bar-Nun; J. J. Berthelier; A. Bieler; P. Bochsler; C. Briois; U. Calmonte; M. Combi; J. De Keyser; P. Eberhardt; B. Fiethe; S. Fuselier; S. Gasc; T. I. Gombosi; K.C. Hansen; M. Hässig; A. Jäckel; E. Kopp; A. Korth; L. LeRoy; U. Mall; B. Marty; O. Mousis; E. Neefs; T. Owen; H. Rème; M. Rubin; T. Sémon; C.-Y. Tzou; H. Waite; P. Wurz
Source:
Science 2015 v.347 no.6220 pp. 1261952
ISSN:
0036-8075
Subject:
oceans; organic compounds; provenance; spectrometers
Abstract:
... The provenance of water and organic compounds on Earth and other terrestrial planets has been discussed for a long time without reaching a consensus. One of the best means to distinguish between different scenarios is by determining the deuterium-to-hydrogen (D/H) ratios in the reservoirs for comets and Earth’s oceans. Here, we report the direct in situ measurement of the D/H ratio in the Jupiter ...
DOI:
10.1126/science.1261952

28. A 2D proton J-resolved NMR method for direct measurements on heterogeneous foods

Author:
Yuqing Huang; Kaiyu Wang; Weinan Lai; Chunhua Tan; Shuai Chen; Shuhui Cai; Zhong Chen
Source:
Food research international 2016 v.80 pp. 70-77
ISSN:
0963-9969
Subject:
Danio rerio; chemical analysis; chemical composition; chemical structure; fish; foods; nuclear magnetic resonance spectroscopy; pulp; spectral analysis; spectrometers; tomatoes
Abstract:
... NMR spectroscopy is recognized as a powerful tool for food analyses on chemical composition determination, molecular structure elucidation, and functional component identification. Due to inhomogeneous line-broadening effects originating from sample heterogeneities and residual anisotropic interactions, high-resolution NMR available for analyses on heterogeneous food samples generally recurs to sa ...
DOI:
10.1016/j.foodres.2015.12.027

29. A 3-in-1 Hand-Held Ambient Mass Spectrometry Interface for Identification and 2D Localization of Chemicals on Surfaces

Author:
Christina Meisenbichler; Florian Kluibenschedl; Thomas Müller
Source:
Analytical chemistry 2020 v.92 no.21 pp. 14314-14318
ISSN:
1520-6882
Subject:
analytical chemistry; cameras; desorption; drugs; electrospray ionization mass spectrometry; ionization; molecular weight; spectrometers; technology
Abstract:
... Desorption electrospray ionization (DESI), easy ambient sonic-spray ionization (EASI) and low-temperature plasma (LTP) ionization are powerful ambient ionization techniques for mass spectrometry. However, every single method has its limitation in terms of polarity and molecular weight of analyte molecules. After the miniaturization of every possible component of the different ion sources, we final ...
DOI:
10.1021/acs.analchem.0c02615

30. A 3-year field study on lead immobilisation in paddy soil by a novel active silicate amendment

Author:
Hanghang Zhao; Jianxin Zhang; Feng Wu; Xunrong Huang; Fuhao Liu; Lu Wang; Xin Zhao; Xiongfei Hu; Pengcheng Gao; Bo Tang; Puhui Ji
Source:
Environmental pollution 2022 v.292 pp. 118325
ISSN:
0269-7491
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; adsorption; cost effectiveness; electrostatic interactions; field experimentation; fly ash; food production; food safety; hot water treatment; human health; ion exchange; lead; microstructure; paddy soils; polluted soils; pollution; remediation; rice; silicates; spectrometers; toxicity
Abstract:
... Lead (Pb) is a toxic metal in industrial production, which can seriously threat to human health and food safety. Thus, it is particularly crucial to reduce the content of Pb in the environment. In this study, raw fly ash (FA) was used to synthesise a new active silicate materials (IM) employing the low-temperature-assisted alkali (NaOH) roasting approach. The IM was further synthesised to form zeo ...
DOI:
10.1016/j.envpol.2021.118325

31. A 3D miniaturized solid-state chemiluminescence sensor based on ruthenium functionalized polymeric monolith for the detection of pharmaceutical drugs

Author:
Entesar Al-Hetlani; Bessy D’Cruz; Mohamed O. Amin
Source:
Journal of materials science 2020 v.55 no.27 pp. 13232-13243
ISSN:
0022-2461
Subject:
Fourier transform infrared spectroscopy; calibration; chemiluminescence; cost effectiveness; electrostatic interactions; fluorescence; forensic sciences; isoelectric point; micropores; oxalates; oxidants; polymers; ruthenium; spectrometers; surface area
Abstract:
... For the first time, a 3D network of poly(methacrylic acid-co-ethylene dimethacrylate (poly(MAA-co-EDMA)) monolith is used as a solid support for a miniaturized solid-state chemiluminescence (CL) system. The positively charged Ru(bpy)₃²⁺ complex was electrostatically linked to the negatively charged monolith to form Ru(bpy)₃²⁺ -poly(MAA-co-EDMA). The Ru(bpy)₃²⁺ -poly(MAA-co-EDMA) was thoroughly stu ...
DOI:
10.1007/s10853-020-04974-z

32. A 5-Micron-Bright Spot on Titan: Evidence for Surface Diversity

Author:
Barnes, Jason W.; Brown, Robert H.; Turtle, Elizabeth P.; McEwen, Alfred S.; Lorenz, Ralph D.; Janssen, Michael; Schaller, Emily L.; Brown, Michael E.; Buratti, Bonnie J.; Sotin, Christophe; Griffith, Caitlin; Clark, Roger; Perry, Jason; Fussner, Stephanie; Barbara, John; West, Richard; Elachi, Charles; Bouchez, Antonin H.; Roe, Henry G.; Baines, Kevin H.; Bellucci, Giancarlo; Bibring, Jean-Pierre; Capaccioni, Fabrizio; Cerroni, Priscilla; Combes, Michel; Coradini, Angioletta; Cruikshank, Dale P.; Drossart, Pierre; Formisano, Vittorio; Jaumann, Ralf; Langevin, Yves; Matson, Dennis L.; McCord, Thomas B.; Nicholson, Phillip D.; Sicardy, Bruno
Source:
Science 2005 v.310 no.5745 pp. 92-95
ISSN:
0036-8075
Subject:
geophysics; image analysis; spectrometers; wavelengths
Abstract:
... Observations from the Cassini Visual and Infrared Mapping Spectrometer show an anomalously bright spot on Titan located at 80°W and 20°S. This area is bright in reflected light at all observed wavelengths, but is most noticeable at 5 microns. The spot is associated with a surface albedo feature identified in images taken by the Cassini Imaging Science Subsystem. We discuss various hypotheses about ...
DOI:
10.1126/science.1117075

33. A Bayesian Estimation Model for Transient Engine Exhaust Characterization Using Fourier Transform Infrared Spectroscopy

Author:
Wilson David; Allen Casey
Source:
Energy & Fuels 2017 v.31 no.10 pp. 11156-11168
ISSN:
1520-5029
Subject:
Bayesian theory; Fourier transform infrared spectroscopy; emissions; fuels; mixing; models; nitric oxide; pollutants; spectrometers; statistical analysis
Abstract:
... Comprehensive emissions models extensively use engine exhaust data from vehicle experiments to represent the relationship between fuel composition and pollutants. However, the predicted emissions from these models often neglect the effects of transients and speed-load history. Fourier transform infrared (FTIR) spectroscopy is a high frequency measurement technique capable of comprehensive speciati ...
DOI:
10.1021/acs.energyfuels.7b02224

34. A Bisboronic Acid Sensor for Ultra-High Selective Glucose Assay by ¹⁹F NMR Spectroscopy

Author:
Xu-dong Gao; Xin-zhen Du; Yan-ping Shi
Source:
Analytical chemistry 2021 v.93 no.19 pp. 7220-7225
ISSN:
1520-6882
Subject:
analytical chemistry; biomedical research; body fluids; detection limit; diabetes mellitus; glucose; humans; nuclear magnetic resonance spectroscopy; spectrometers; urine
Abstract:
... Glucose is a significant analyte both in biology and biomedical science, it is of great importance to selectively detect glucose both in body fluids and complex mixture. In this study, a simple ¹⁹F NMR based sensor was synthesized easily, which exhibited a high selectivity and robust anti-interference ability toward glucose detection both in a mixture containing up to 10 saccharides and human urin ...
DOI:
10.1021/acs.analchem.1c00262

35. A Cloud masking algorithm for the XBAER aerosol retrieval using MERIS data

Author:
Linlu Mei; Marco Vountas; Luis Gómez-Chova; Vladimir Rozanov; Malte Jäger; Wolfhardt Lotz; John P. Burrows; Rainer Hollmann
Source:
Remote sensing of environment 2017 v.197 pp. 141-160
ISSN:
0034-4257
Subject:
aerosols; algorithms; altitude; biomass; burning; color; dust; experts; geophysics; ice; image analysis; instrumentation; lidar; models; radiative transfer; reflectance; remote sensing; snow; spectrometers; vegetation
Abstract:
... To determine aerosol optical thickness, AOT, and other geophysical parameters describing conditions in the atmosphere and at the earth's surface by inversion of remote sensing measurements from space based instrumentation, it is necessary to separate ground scenes into cloud free and cloudy or cloud contaminated. Identifying the presence of cloud in a ground scene and establishing an accurate and ...
DOI:
10.1016/j.rse.2016.11.016

36. A Combined System of Paper Device and Portable Spectrometer for the Detection of Pesticide Residues

Author:
Muna Fuyal; Basant Giri
Source:
Food analytical methods 2020 v.13 no.7 pp. 1492-1502
ISSN:
1936-9751
Subject:
acetylcholinesterase; chemical species; colorimetry; detection limit; dichlorvos; enzymatic reactions; enzyme inhibition; image analysis; paper; spectrometers; wavelengths
Abstract:
... Pesticide residues are detected in food items globally at levels that may cause health problems. Paper-based analytical devices have emerged as an alternative low-cost and field-based tools for determining target analytes including the pesticide residues. However, the paper devices with colorimetric detection system are limited by lower sensitivity due to their inability to record wavelength speci ...
DOI:
10.1007/s12161-020-01770-y

37. A Comparative Study of PLSR and SVM-R with Various Preprocessing Techniques for the Quantitative Determination of Soluble Solids Content of Hardy Kiwi Fruit by a Portable Vis/NIR Spectrometer

Author:
Shagor Sarkar; Jayanta Kumar Basak; Byeong Eun Moon; Hyeon Tae Kim
Source:
Foods 2020 v.9 no.8 pp. -
ISSN:
2304-8158
Subject:
algorithms; area; autumn; calibration; comparative study; correlation; data collection; exhibitions; foods; fruits; harvest date; kiwifruit; least squares; model validation; near-infrared spectroscopy; nonlinear models; prediction; quantitative analysis; research; spectrometers; total soluble solids; South Korea
Abstract:
... Linear partial least square and non-linear support vector machine regression analysis with various preprocessing techniques and their combinations were used to determine the soluble solids content of hardy kiwi fruits by a handheld, portable near-infrared spectroscopy. Fruits of four species, namely Autumn sense (A), Chungsan (C), Daesung (D), and Green ball (Gb) were collected from five different ...
DOI:
10.3390/foods9081078

38. A Comparison of Multispectral ASTER and Hyperspectral AVIRIS Multiple Endmember Spectral Mixture Analysis for Sagebrush and Herbaceous Cover in Yellowstone

Author:
Stacey Fairweather; Christopher Potter; Robert Crabtree; Shuang Li
Source:
Photogrammetric engineering and remote sensing 2012 v.78 no.1 pp. 23-33
ISSN:
0099-1112
Subject:
Advanced Spaceborne Thermal Emission and Reflection Radiometer; Artemisia; biodiversity; forbs; grasses; habitats; image analysis; national parks; phenology; remote sensing; resource management; satellites; semiarid zones; soil; spectral analysis; spectrometers; vegetation
Abstract:
...

Remote sensing techniques can provide information on habitat quality, biodiversity, and cover change at the regional scales of sagebrush-steppe dominated systems and with the repeatability necessary for resource management. In this paper, we present the results of multiple endmember spectral mixture analysis applied to Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) an ...

DOI:
10.14358/PERS.78.1.23

39. A DFT-Based Computational-Experimental Methodology for Synthetic Chemistry: Example of Application to the Catalytic Opening of Epoxides by Titanocene

Author:
Jaraíz Martín; Enríquez Lourdes; Pinacho Ruth; Rubio José E.; Lesarri Alberto; López-Pérez José L.
Source:
Journal of organic chemistry 2017 v.82 no.7 pp. 3760-3766
ISSN:
1520-6904
Subject:
Fourier transform infrared spectroscopy; chemical reactions; chemical structure; epoxides; instrumentation; mechanistic models; monitoring; nuclear magnetic resonance spectroscopy; organic chemistry; prediction; reaction kinetics; spectral analysis; spectrometers; ultraviolet-visible spectroscopy
Abstract:
... A novel DFT-based Reaction Kinetics (DFT-RK) simulation approach, employed in combination with real-time data from reaction monitoring instrumentation (like UV–vis, FTIR, Raman, and 2D NMR benchtop spectrometers), is shown to provide a detailed methodology for the analysis and design of complex synthetic chemistry schemes. As an example, it is applied to the opening of epoxides by titanocene in TH ...
DOI:
10.1021/acs.joc.7b00220

40. A Dedicated Mass Spectrometer Tuning Method for SFC–MS and Evaluation of Two Different Linear Restrictor Types Used in the Operation of a Split Flow Pre-Back Pressure Regulator SFC–MS Interface

Author:
Wei Guo; Ben Li; Haijun Chi; Edward D. Ramsey
Source:
Chromatographia 2018 v.81 no.9 pp. 1257-1267
ISSN:
0009-5893
Subject:
ammonia; carbon dioxide; chromatography; drugs; liquids; mass spectrometry; methanol; mixing; monensin; silica; spectrometers
Abstract:
... The operation of a SFC–MS system has been improved. The SFC–MS interface uses a post-column make-up flow of liquid whose supply line to the SFC–MS interface mixing tee is equipped with an injection valve. Prior to analysis, this arrangement permits a stable flow of a dilute tune solution of analyte(s) for the exact amount of time required to optimize mass spectrometry tuning. Advantageously, with ...
DOI:
10.1007/s10337-018-3565-6

41. A Degradation-Profile Comparison Technique for Mass Spectrometric Analysis of Water-Soluble Cellulose Ethers

Author:
H.R. Harless; R.L. Anderson
Source:
Textile research journal 1970 v.40 no.5 pp. 448-450
ISSN:
0040-5175
Subject:
additives; cellulose; ethers; fabrics; mass spectrometry; polypropylenes; qualitative analysis; spectrometers; textile fibers; thermal degradation; water solubility
Abstract:
... A degradation-profile technique has been developed for the qualitative analysis of water-soluble cellulosic ethers. The technique, is based on mass spectra obtained by thermal degradation of the ethers in a time-of-flight mass spectrometer. The method allows direct comparisons of two or more of the modified cellulosic products. Differences in the profiles of methyl, hydroryethyl, and hydroxypropyl ...
DOI:
10.1177/004051757004000509

42. A Differentially Pumped Dual Linear Quadrupole Ion Trap (DLQIT) Mass Spectrometer: A Mass Spectrometer Capable of MSn Experiments Free From Interfering Reactions

Author:
Owen Benjamin C.; Jarrell Tiffany M.; Schwartz Jae C.; Oglesbee Rob; Carlsen Mark; Archibold Enada F.; Kenttämaa Hilkka I.
Source:
Analytical chemistry 2013 v.85 no.23 pp. 11284-11290
ISSN:
1520-6882
Subject:
dissociation; ions; oxygen; spectrometers
Abstract:
... A novel differentially pumped dual linear quadrupole ion trap (DLQIT) mass spectrometer was designed and built to facilitate tandem MS experiments free from interfering reactions. The instrument consists of two differentially pumped Thermo Scientific linear quadrupole ion trap (LQIT) systems that have been connected via an ion transfer octupole encased in a machined manifold. Tandem MS experiments ...
DOI:
10.1021/ac401956f

43. A Direct Method for Determining Sulfur in Carbon Materials by Atomic Emission Spectrometry with an Arc Excitation Source

Author:
D. O. Antonov; E. G. Silkis; B. K. Zuev
Source:
Journal of analytical chemistry 2021 v.76 no.5 pp. 578-584
ISSN:
1061-9348
Subject:
analytical chemistry; atomic absorption spectrometry; detection limit; diodes; graphene; spectrometers; sulfur
Abstract:
... Emission spectrometry with an argon arc source, ensuring the significant suppression of interferences with the molecular spectrum of CN, is used for the rapid direct determination of sulfur in pure graphite powders. A method of the time selection of the analytical signal of sulfur at the line 921.286 nm is proposed (signal registration within a certain interval of 9.8 s). The limit of detection fo ...
DOI:
10.1134/S1061934821050063

44. A Direct-Infusion- and HPLC-ESI-Orbitrap-MS Approach for the Characterization of Intact PEGylated Proteins

Author:
Forstenlehner Ines C.; Holzmann Johann; Scheffler Kai; Wieder Wolfgang; Toll Hansjörg; Huber Christian G.
Source:
Analytical chemistry 2014 v.86 no.1 pp. 826-834
ISSN:
1520-6882
Subject:
electrospray ionization mass spectrometry; ethylene glycol; formic acid; granulocyte colony-stimulating factor; high performance liquid chromatography; humans; methionine; molecular weight; oxidation; polyethylene glycol; proteins; spectrometers; triethylamine
Abstract:
... The characterization of proteins modified with poly(ethylene glycol) (PEG), such as recombinant human granulocyte-colony stimulating factor (PEGylated rhG-CSF or pegfilgrastim), by electrospray ionization-mass spectrometry (ESI-MS) constitutes a challenge due to the overlapping protein charge state pattern and PEG polydispersity. In order to minimize spectral overlaps, charge reduction by means of ...
DOI:
10.1021/ac403390y

45. A Fast Retrieval of Cloud Parameters Using a Triplet of Wavelengths of Oxygen Dimer Band around 477 nm

Author:
Haklim Choi; Xiong Liu; Gonzalo Gonzalez Abad; Jongjin Seo; Kwang-Mog Lee; Jhoon Kim
Source:
Remote Sensing 2021 v.13 no.1 pp. -
ISSN:
2072-4292
Subject:
absorption; aerosols; algorithms; altitude; environmental monitoring; geometry; information; light; observational studies; oxygen; ozone; paper; pressure; radiative transfer; remote sensing; solar radiation; spectrometers; wavelengths
Abstract:
... Clouds act as a major reflector that changes the amount of sunlight reflected to space. Change in radiance intensity due to the presence of clouds interrupts the retrieval of trace gas or aerosol properties from satellite data. In this paper, we developed a fast and robust algorithm, named the fast cloud retrieval algorithm, using a triplet of wavelengths (469, 477, and 485 nm) of the O₂–O₂ absorp ...
DOI:
10.3390/rs13010152

46. A Fast, Straightforward and Inexpensive Method for the Authentication of Baijiu Spirit Samples by Fluorescence Spectroscopy

Author:
Rachel L. Burns; Raegan Alexander; Liliya Snaychuk; John C. Edwards; Neil Fitzgerald; Pei Gao; Donghui Quan; Chris Douvris; Trey Vaughan; Derek D. Bussan
Source:
Beverages 2021 v.7 no.3 pp. -
ISSN:
2306-5710
Subject:
analytical chemistry; fluorescence emission spectroscopy; markets; prices; quartz; spectrometers; vodka; wastes; whisky; East Asia; North America
Abstract:
... The Chinese spirit baijiu is currently the world’s bestselling spirit, with more than ten billion liters sold in 2018. This is a figure that puts its sales higher than whiskey, vodka, gin, and tequila combined. The multitude of baijiu varieties available in the market differ in several ways ranging from aging to the traditional artisanship involved in producing the final spirit to several other fe ...
DOI:
10.3390/beverages7030065

47. A Green Design for Lubrication: Multifunctional System Containing Fe3O4@MoS2 Nanohybrid

Author:
Lei Liu; Songlong Jiao; Yitian Peng; Wei Zhou
Source:
ACS sustainable chemistry & engineering 2018 v.6 no.6 pp. 7372-7379
ISSN:
2168-0485
Subject:
X-ray diffraction; design for environment; energy-dispersive X-ray analysis; friction; hot water treatment; iron oxides; liquids; lubricants; lubrication; molybdenum disulfide; nanohybrids; oils; photocatalysis; scanning electron microscopy; spectrometers; spectroscopy; transmission electron microscopy
Abstract:
... In this work, a green and sustainable strategy for the combined design containing both lubrication and photocatalytic degradation at different stages of base oils has been suggested. More concretely, Fe₃O₄@MoS₂ nanohybrid was prepared and used as an additive for liquid paraffin (LP), resulting in enhanced lubricating properties together with significant photocatalytic degradation performance. The ...
DOI:
10.1021/acssuschemeng.7b04801

48. A HILIC-UHPLC-MS/MS untargeted urinary metabonomics combined with quantitative analysis of five polar biomarkers on osteoporosis rats after oral administration of Gushudan

Author:
Xiao Wu; Yue Huang; Jinghan Sun; Yongqing Wen; Feng Qin; Longshan Zhao; Zhili Xiong
Source:
Journal of Chromatography B 2017 pp. -
ISSN:
1570-0232
Subject:
urine; ionization; tinidazole; creatinine; hypoxanthine; oral administration; betaine; metabolites; biomarkers; energy metabolism; cytosine; amino acid metabolism; metabolomics; taurine; quantitative analysis; monitoring; t-test; hydrophilic interaction chromatography; models; principal component analysis; osteoporosis; rats; lipid metabolism; spectrometers; ultra-performance liquid chromatography
Abstract:
... A HILIC-UHPLC-MS/MS untargeted urinary metabonomic method combined with quantitative analysis of five potential polar biomarkers in rat urine was developed and validated, to further understand the anti-osteoporosis effect of Gushudan(GSD) and its mechanism on prednisolone-induced osteoporosis(OP) rats in this study. The metabolites were separated and identified on Waters BEH HILIC (2.1mm×100mm, 1. ...
DOI:
10.1016/j.jchromb.2017.10.005

49. A High-Resolution LC–MS/MS Method for the Quantitative Determination of Artemether and Its Metabolite Dihydroartemisinin in Human Plasma and Its Application to Pharmacokinetic Studies

Author:
Fazli Khuda; Zafar Iqbal; Yasar Shah; Muhammad Abbas; Zakiullah; Muhammad Hassan
Source:
Chromatographia 2016 v.79 no.9-10 pp. 609-618
ISSN:
0009-5893
Subject:
acetonitrile; artemisinin; atmospheric pressure; detection limit; formic acid; humans; ionization; liquid chromatography; metabolites; monitoring; pharmacokinetics; quantitative analysis; spectrometers; tandem mass spectrometry; volunteers
Abstract:
... A highly sensitive and rapid liquid chromatography–tandem mass spectrometry method was developed and validated for the determination of artemether and its metabolite dihydroartemisinin in human plasma using artemisinin as an internal standard. Chromatographic separation was achieved on a Supelco Discovery HS C₁₈ RP column (150 mm × 4.6 mm, 5 µm; Bellefonte, USA) using acetonitrile and water with 0 ...
DOI:
10.1007/s10337-016-3064-6

50. A High-Throughput, Multiplexed Kinase Assay Using a Benchtop Orbitrap Mass Spectrometer To Investigate the Effect of Kinase Inhibitors on Kinase Signaling Pathways

Author:
Kunz Ryan C.; McAllister Fiona E.; Rush John; Gygi Steven P.
Source:
Analytical chemistry 2012 v.84 no.14 pp. 6233-6239
ISSN:
1520-6882
Subject:
computer software; immune response; inflammation; inhibitory concentration 50; peptides; phosphotransferases (kinases); post-translational modification; protein phosphorylation; signal transduction; spectrometers
Abstract:
... Protein phosphorylation is an important and ubiquitous post-translational modification in eukaryotic biological systems. The KAYAK (Kinase ActivitYAssay for Kinome profiling) assay measures the phosphorylation rates of dozens of peptide substrates simultaneously, directly from cell lysates. Here, we simplified the assay by removing the phosphopeptide enrichment step, increasing throughput while ma ...
DOI:
10.1021/ac301116z

51. A Highly Sensitive Real-time Immuno-PCR Assay for Detecting Benzo[a]pyrene in Food Samples by Application of Biotin-Streptavidin System

Author:
Zhen Ma; Huisheng Zhuang
Source:
Food analytical methods 2018 v.11 no.3 pp. 862-872
ISSN:
1936-9751
Subject:
DNA; antigens; benzo(a)pyrene; cross reaction; detection limit; ecosystems; gas chromatography-mass spectrometry; human health; immunoassays; polyclonal antibodies; polycyclic aromatic hydrocarbons; spectrometers; streptavidin; vegetables
Abstract:
... Benzo[a]pyrene (BaP), a kind of polycyclic aromatic hydrocarbon, has great potential hazards to the ecosystem and human health. In this study, based on the preparation of BaP immunogen and coating antigen, a specific polyclonal antibody targeting BaP was generated, and a highly sensitive real-time immuno-PCR assay using the biotin-streptavidin system (BA-IPCR) was developed for detecting BaP in ve ...
DOI:
10.1007/s12161-017-1046-4

52. A Hylogger-Itrax core-scanner comparison for multi-scale high-resolution petrophysical characterisation workflow

Author:
Amalia Yunita Halim; Sarah Jane Kelloway; Christopher Marjo; Klaus Regenauer-Lieb
Source:
Applied geochemistry 2021 v.133 pp. 104956
ISSN:
0883-2927
Subject:
X-radiation; X-ray diffraction; automation; data collection; fluorescence; geochemistry; industry; oils; scanners; spectrometers; volcanic rocks
Abstract:
... Recent advances in core scanning technologies allow for fast and non-destructive chemical and mineral profiling of rock samples for mineral services and oil and gas exploration. The aim of these automatic core scan methods is to obtain valuable information for profiling drill core cuttings with minimum sample preparation at relatively high speed. In the last decade, a core logging system using an ...
DOI:
10.1016/j.apgeochem.2021.104956

53. A LC-MS³ strategy to determine lamotrigine by Q-Q-trap tandem mass spectrometry coupled with triple stage fragmentation to enhance sensitivity and selectivity

Author:
Meiyun Shi; Qiuhong Jiang; Qiushi Lyu; Zhengting Yuan; Lili Deng; Lei Yin
Source:
Analytical methods 2021 v.13 no.38 pp. 4478-4484
ISSN:
1759-9679
Subject:
formic acid; high performance liquid chromatography; humans; liquids; methanol; solvents; spectrometers; tandem mass spectrometry
Abstract:
... A high-performance liquid chromatography tandem mass spectrometry cubed (HPLC/MS³) method was developed and validated to quantify lamotrigine in human plasma with carbamazepine as an internal standard. The HPLC/MS/MS system is composed of a Shimadzu UFLC XR high-performance liquid chromatograph coupled with a hybrid linear ion trap triple quadrupole mass spectrometer. Following simple protein prec ...
DOI:
10.1039/d1ay01372f

54. A LED-based fiber-optic sensor integrated with lab-on-valve manifold for colorimetric determination of free chlorine in water

Author:
Yan Xiong; Jun Tan; Shenwen Fang; Chengjie Wang; Qing Wang; Jiayi Wu; Jie Chen; Ming Duan
Source:
Talanta 2017 v.167 pp. 103-110
ISSN:
0039-9140
Subject:
absorbance; chlorine; colorimetry; detection limit; fiber optics; fluorescence; monitoring; silica; spectrometers; wavelengths
Abstract:
... In this work, a colorimetric methodology was developed for free chlorine determination by constructing a fiber-optic sensor (FOS) which was designed by using a small LED as light source and two silica fibers as light transmission elements. Then the FOS was integrated with the sequential injection lab-on-valve (SI-LOV) manifold to fabricate a FOS-SI-LOV system for free chlorine detection. The color ...
DOI:
10.1016/j.talanta.2017.02.014

55. A Large Underestimate of Formic Acid from Tropical Fires: Constraints from Space-Borne Measurements

Author:
Chaliyakunnel S.; Millet D.B.; Wells K.C.; Cady-Pereira K.E.; Shephard M.W.
Source:
Environmental Science & Technology 2016 v.50 no.11 pp. 5631-5640
ISSN:
1520-5851
Subject:
acidity; biomass; burning; emissions; fires; formic acid; models; spectrometers; tropics; troposphere; Africa
Abstract:
... Formic acid (HCOOH) is one of the most abundant carboxylic acids and a dominant source of atmospheric acidity. Recent work indicates a major gap in the HCOOH budget, with atmospheric concentrations much larger than expected from known sources. Here, we employ recent space-based observations from the Tropospheric Emission Spectrometer with the GEOS-Chem atmospheric model to better quantify the HCOO ...
DOI:
10.1021/acs.est.5b06385

56. A Mass-Spectrometry-Based Framework To Define the Extent of Disorder in Proteins

Author:
Beveridge Rebecca; Covill Sam; Pacholarz Kamila J.; Kalapothakis Jason M. D.; MacPhee Cait E.; Barran Perdita E.
Source:
Analytical chemistry 2014 v.86 no.22 pp. 10979-10991
ISSN:
1520-6882
Subject:
DNA-binding domains; amino acids; amyloid; avidin; blood serum; bovine serum albumin; cytochrome c; electrospray ionization mass spectrometry; humans; immunoglobulin G; ionic strength; ionization; ions; melittin; models; ovalbumin; pH; prealbumin; solvents; spectrometers; ubiquitin
Abstract:
... In the past decade, mass spectrometry (MS) coupled with electrospray ionization (ESI) has been extensively applied to the study of intact proteins and their complexes, often without the requirement of labels. Solvent conditions (for example, pH, ionic strength, and concentration) affect the observed desolvated species; the ease of altering such extrinsic factors renders ESI-MS an appropriate metho ...
DOI:
10.1021/ac5027435

57. A Method for Continuous 239Pu Determinations in Arctic and Antarctic Ice Cores

Author:
Arienzo M. M.; McConnell J. R.; Chellman N.; Criscitiello A. S.; Curran M.; Fritzsche D.; Kipfstuhl S.; Mulvaney R.; Nolan M.; Opel T.; Sigl M.; Steffensen J.P.
Source:
Environmental Science & Technology 2016 v.50 no.13 pp. 7066-7073
ISSN:
1520-5851
Subject:
half life; ice; latitude; methodology; plutonium; radionuclides; spectrometers; Antarctic region; Antarctica; Arctic region; Greenland
Abstract:
... Atmospheric nuclear weapons testing (NWT) resulted in the injection of plutonium (Pu) into the atmosphere and subsequent global deposition. We present a new method for continuous semiquantitative measurement of ²³⁹Pu in ice cores, which was used to develop annual records of fallout from NWT in ten ice cores from Greenland and Antarctica. The ²³⁹Pu was measured directly using an inductively coupled ...
DOI:
10.1021/acs.est.6b01108

58. A Methodological Approach to the Analysis of Rocks and Meteorites by Inductively Coupled Plasma Atomic Emission Spectrometry

Author:
E. M. Sedykh; I. N. Gromyak; K. A. Lorents; A. Ya. Skripnik; V. P. Kolotov
Source:
Journal of analytical chemistry 2019 v.74 no.4 pp. 393-400
ISSN:
1061-9348
Subject:
atomic absorption spectrometry; phosphorus; rocks; spectrometers; sulfur
Abstract:
... The capabilities of the ICAP-6500 Duo high-resolution echelle spectrometer (Thermo Scientific) for the elemental analysis of geochemical materials and extraterrestrial matter have been investigated. The features of the determination of elements in chondritic meteorites are studied, and appropriate procedures, including sample preparation, are developed. Main (including phosphorus and sulfur) and i ...
DOI:
10.1134/S1061934819040129

59. A Microelectromechanical Systems-Enabled, Miniature Triple Quadrupole Mass Spectrometer

Author:
Wright Steven; Malcolm Andrew; Wright Christopher; O’Prey Shane; Crichton Edward; Dash Neil; Moseley Richard W.; Zaczek Wojciech; Edwards Peter; Fussell Richard J.; Syms Richard R. A.
Source:
Analytical chemistry 2015 v.87 no.6 pp. 3115-3122
ISSN:
1520-6882
Subject:
apples; atmospheric pressure; ions; pesticides; quantitative analysis; spectrometers; thiabendazole
Abstract:
... Miniaturized mass spectrometers are becoming increasingly capable, enabling the development of many novel field and laboratory applications. However, to date, triple quadrupole tandem mass spectrometers, the workhorses of quantitative analysis, have not been significantly reduced in size. Here, the basis of a field-deployable triple quadrupole is described. The key development is a highly miniatur ...
DOI:
10.1021/acs.analchem.5b00311

60. A Microfluidic SPLITT Device for Fractionating Low-Molecular Weight Samples

Author:
Kinde Tristan F.; Dutta Debashis
Source:
Analytical chemistry 2013 v.85 no.15 pp. 7167-7172
ISSN:
1520-6882
Subject:
electric field; electrodes; electroosmosis; electrophoresis; fractionation; glass; ionization; mixing; peptides; spectrometers
Abstract:
... In this article, we report the design of a microfluidic split flow thin cell (SPLITT) fractionation device with internal electrodes placed across the width of its analysis channel for assaying low-molecular weight samples. The reported device allows the realization of lateral electric fields and separation distances of the orders of 100 V/cm and 500 μm, respectively, that are suitable for fraction ...
DOI:
10.1021/ac400843s

61. A Miniature Multilevel Structures for Lossless Ion Manipulations Ion Mobility Spectrometer with Wide Mobility Range Separation Capabilities

Author:
Adam L. Hollerbach; Randolph V. Norheim; Pearl Kwantwi-Barima; Richard D. Smith; Yehia M. Ibrahim
Source:
Analytical chemistry 2021 v.94 no.4 pp. 2180-2188
ISSN:
1520-6882
Subject:
analytical chemistry; electrodes; peptides; spectrometers; spectroscopy
Abstract:
... Ion mobility spectrometry employing structures for lossless ion manipulations (SLIM-IMS) is an attractive gas-phase separation technique due to its ability to achieve unprecedented effective ion path lengths (>1 km) and IMS resolving powers in a small footprint. The emergence of multilevel SLIM technology, where ions are transferred between vertically stacked SLIM electrode surfaces, has subsequen ...
DOI:
10.1021/acs.analchem.1c04700

62. A Miniature Particle Mass Spectrometer

Author:
Xi Huang; Jinlong Jiang; Yiming Zhang; Lingpeng Zhan; Chaozi Liu; Caiqiao Xiong; Zongxiu Nie
Source:
Analytical chemistry 2019 v.91 no.15 pp. 9393-9397
ISSN:
1520-6882
Subject:
aerodynamics; chemical composition; data collection; desorption; electric potential difference; erythrocytes; ionization; mass spectrometry; mice; microparticles; polystyrenes; silica; spectrometers
Abstract:
... Microparticles play important roles in our life. Besides chemical compositions and morphology, the size of microparticles will also decide their behavior in the environment or in organisms. Weighing the mass of microparticles by mass spectrometry is a useful method to characterize their size. In this technical note, a miniature particle mass spectrometer with an aerodynamic desorption/ionization i ...
DOI:
10.1021/acs.analchem.9b01069

63. A Modified Drift Tube Ion Mobility-Mass Spectrometer for Charge-Multiplexed Collision-Induced Unfolding

Author:
Daniel D. Vallejo; Daniel A. Polasky; Ruwan T. Kurulugama; Joseph D. Eschweiler; John C. Fjeldsted; Brandon T. Ruotolo
Source:
Analytical chemistry 2019 v.91 no.13 pp. 8137-8146
ISSN:
1520-6882
Subject:
amino acid sequences; antibodies; biopharmaceuticals; data collection; dissociation; electric potential difference; gases; ions; post-translational modification; protein unfolding; proteins; spectrometers
Abstract:
... Collision-induced unfolding (CIU) of protein ions and their noncovalent complexes offers relatively rapid access to a rich portfolio of biophysical information, without the need to tag or purify proteins prior to analysis. Such assays have been characterized extensively for a range of therapeutic proteins, proving exquisitely sensitive to alterations in protein sequence, structure, and post-transl ...
DOI:
10.1021/acs.analchem.9b00427

64. A Multilevel Analysis of the Impact of Land Use on Interannual Land-Cover Change in East Africa

Author:
Serneels, S.; Linderman, M.; Lambin, E. F.
Source:
Ecosystems 2007 v.10 no.3 pp. 402-418
ISSN:
1432-9840
Subject:
climate; ecosystems; grazing; herbivores; humans; image analysis; land cover; land use; livestock; models; moderate resolution imaging spectroradiometer; phenology; rain; spatial data; spectrometers; time series analysis; vegetation types; Eastern Africa
Abstract:
... The aim of this study was to characterize the short-term land-cover change processes that were detected in Eastern Africa, based on a set of change metrics that allow for the quantification of interannual changes in vegetation productivity, changes in vegetation phenology and a combination of both. We tested to what extent land use, fire activity and livestock grazing modified the vegetation respo ...
DOI:
10.1007/s10021-007-9026-y

65. A Near-Infrared “Matchbox Size” Spectrometer to Detect and Quantify Malaria Parasitemia

Author:
John A. Adegoke; Kamila Kochan; Philip Heraud; Bayden R. Wood
Source:
Analytical chemistry 2021 v.93 no.13 pp. 5451-5458
ISSN:
1520-6882
Subject:
World Health Organization; analytical chemistry; detection limit; least squares; malaria; parasitemia; patients; point-of-care systems; prediction; principal component analysis; signal-to-noise ratio; spectrometers; spectrophotometers; wavelengths
Abstract:
... New point-of-care diagnostic approaches for malaria that are sensitive to low parasitemia, easy to use in a field setting, and affordable are urgently required to meet the World Health Organization’s objective of reducing malaria cases and related life losses by 90% globally on or before 2030. In this study, an inexpensive “matchbox size” near-infrared (NIR) spectrophotometer was used for the firs ...
DOI:
10.1021/acs.analchem.0c05103

66. A Nested Case–Control Study on Plasma Vitamin E and Risk of Cancer: Evidence of Effect Modification by Selenium [Erratum: July 2019, v.119(7), p.1210]

Author:
Jiancheng Wang; Huiyuan Guo; Tengfei Lin; Yun Song; Hao Zhang; Binyan Wang; Yan Zhang; Jianping Li; Yong Huo; Xiaobin Wang; Xianhui Qin; Xiping Xu
Source:
Journal of the Academy of Nutrition and Dietetics 2019 v.119 no.5 pp. 769-781
ISSN:
2212-2672
Subject:
Chinese people; adults; atomic absorption spectrometry; case-control studies; esophageal neoplasms; gastrointestinal neoplasms; hypertension; liquid chromatography; patients; regression analysis; risk reduction; selenium; spectrometers; vitamin E
Abstract:
... Evidence from epidemiologic studies has been inconsistent regarding the role of vitamin E in cancer incidence risk.The aim of this study was to evaluate the prospective association between baseline plasma vitamin E levels and subsequent cancer risk in Chinese adults with hypertension, and to identify effect modifiers.A nested, case–control study was conducted from 20,702 hypertensive participants ...
DOI:
10.1016/j.jand.2018.11.017

67. A New Approach to Increasing the Resolution of a Mass Spectrometer with Wedge-Shaped Reflectors

Author:
E. A. Sysoeva; A. V. Spakhov; Alexander A. Sysoev
Source:
Journal of analytical chemistry 2017 v.72 no.13 pp. 1350-1353
ISSN:
1061-9348
Subject:
energy; flight; ions; spectrometers
Abstract:
... The paper describes the investigation of the ion-optical properties of a laser TOF mass spectrometer including two successively positioned wedge-shaped ion mirrors. Some specific properties of the configuration of ion trajectories near their reflection in the second ion reflector are found. The dependence of aberrations on ion energy acquired toothed shape for the resolution of the analyzer higher ...
DOI:
10.1134/S1061934817130123

68. A New Approach to the Mass Spectrometric Analysis of Aqueous Electrolyte Solutions Using a Gas-Dynamic Interface with a Gas Jet at the Inlet of a Time-of-Flight Mass Spectrometer with Orthogonal Ion Injection

Author:
V. V. Raznikov; V. V. Zelenov; E. V. Aparina; I. V. Sulimenkov; A. R. Pikhtelev
Source:
Journal of analytical chemistry 2021 v.76 no.13 pp. 1505-1511
ISSN:
1061-9348
Subject:
analytical chemistry; ionization; liquids; mass spectrometry; spectrometers
Abstract:
... We report the results of a study of the effect of a supersonic gas jet on the formation and extraction of analyzed ions from a liquid supplied through a capillary to an RF quadrupole connected to a time-of-flight mass spectrometer with orthogonal ion injection. The supersonic gas jet is formed inside a cylindrical channel and passes through an electron ionization ion source. The results confirm th ...
DOI:
10.1134/S1061934821130104

69. A New Linear Relation for Estimating Surface Broadband Emissivity in Arid Regions Based on FTIR and MODIS Products

Author:
Huoqing Li; Zonghui Liu; Ali Mamtimin; Junjian Liu; Yongqiang Liu; Chenxiang Ju; Hailiang Zhang; Zhibo Gao
Source:
Remote Sensing 2021 v.13 no.9 pp. -
ISSN:
2072-4292
Subject:
Fourier transform infrared spectroscopy; equations; land use; leaf area index; models; reflectance; regression analysis; satellites; soil water; spectrometers; uncertainty; vegetation; China
Abstract:
... Broadband emissivity is a crucial parameter for calculating the radiation budget, still, it adopts a constant value in land surface models due to a lack of adequate observations. Arid regions have complex underlying surfaces and estimations of the broadband emissivity in such areas suffer from high spatial variation and uncertainty. Here, we propose a novel method for estimating broadband emissivi ...
DOI:
10.3390/rs13091686

70. A New Method and Mass Spectrometer Design for TOF-SIMS Parallel Imaging MS/MS

Author:
Fisher Gregory L.; Bruinen Anne L.; Ogrinc Potočnik Nina; Hammond John S.; Bryan Scott R.; Larson Paul E.; Heeren Ron M.A.
Source:
Analytical chemistry 2016 v.88 no.12 pp. 6433-6440
ISSN:
1520-6882
Subject:
image analysis; ions; screening; spectrometers; tandem mass spectrometry
Abstract:
... We report a method for the unambiguous identification of molecules in biological and materials specimens at high practical lateral resolution using a new TOF-SIMS parallel imaging MS/MS spectrometer. The tandem mass spectrometry imaging reported here is based on the precise monoisotopic selection of precursor ions from a TOF-SIMS secondary ion stream followed by the parallel and synchronous collec ...
DOI:
10.1021/acs.analchem.6b01022

71. A New Method for Determination of 15N-Labeled Nitrous Oxide

Author:
R. L. Mulvaney; L. T. Kurtz
Source:
Soil Science Society of America journal 1982 v.46 no.6 pp. 1178-1184
ISSN:
0361-5995
Subject:
carbon dioxide; copper; fertilizers; isotope labeling; nitrogen; nitrous oxide; soil; spectrometers; stable isotopes
Abstract:
... A procedure is described that permits determination of nitrous oxide (N₂O) evolved from soils treated with ¹⁵N-labeled fertilizer. This procedure involves dilution of ¹⁵N-labeled N₂O with a known amount of unenriched dinitrogen (N₂), reduction of the N₂O to N₂ in a heated tube containing reduced copper, and determination of the ratios, ²⁹N₂/²⁸N₂ and ³⁰N₂/(²⁸N₂ + ²⁹N₂), with a dual-inlet ratio mass ...
DOI:
10.2136/sssaj1982.03615995004600060012x

72. A New Method for Quantifying Phosphorus of Various Occurrence Forms in Solid Fuels

Author:
Xujun Chen; Sui Boon Liaw; Hongwei Wu
Source:
Energy & fuels 2019 v.33 no.4 pp. 3311-3321
ISSN:
1520-5029
Subject:
chloroform; cold; ethanol; fuels; hydrogen peroxide; inorganic phosphorus; nucleic acids; orthophosphates; perchloric acid; phospholipids; sodium chloride; spectrometers; tripolyphosphates; ultraviolet radiation; wet digestion method
Abstract:
... Quantification of phosphorus (P) and determination of the occurrence forms of P in solid fuels are important to thermochemical processing of P-containing solid fuels. This study has developed a new three-step method for separating and quantifying the total P in a solid fuel into five major P-containing fractions. These consist of three organic P-containing fractions (i.e., acid-soluble organic P, ...
DOI:
10.1021/acs.energyfuels.9b00361

73. A New Method to Investigate the Intrusion of Water into Porous Hydrophobic Structures under Dynamic Conditions

Author:
Cavazzini Alberto; Marchetti Nicola; Pasti Luisa; Greco Roberto; Dondi Francesco; Laganà Aldo; Ciogli Alessia; Gasparrini Francesco
Source:
Analytical chemistry 2013 v.85 no.1 pp. 19-22
ISSN:
1520-6882
Subject:
chromatography; deuterium oxide; hydrophobicity; silica; spectrometers; stainless steel
Abstract:
... The intrusion of water into the pores of hydrophobic materials is investigated by means of a dynamic flow system. The porous hydrophobic material is packed into a stainless steel chromatographic column, and water is flushed through by means of a high-pressure pump. Back-pressure control is provided by flow restrictors after the column. The applied pressure forces the water to penetrate the pores o ...
DOI:
10.1021/ac303253b

74. A New Pulsed Flow Modulation GC × GC–MS with Cold EI System and Its Application for Jet Fuel Analysis

Author:
Uri Keshet; Alexander B. Fialkov; Tal Alon; Aviv Amirav
Source:
Chromatographia 2016 v.79 no.11-12 pp. 741-754
ISSN:
0009-5893
Subject:
cold; comprehensive two-dimensional gas chromatography; fuels; gas chromatography-mass spectrometry; gases; ions; isomers; isotopes; spectrometers
Abstract:
... We designed and operated a new system of pulsed flow modulation (PFM) two dimensional comprehensive gas chromatography (GC × GC) mass spectrometry (MS). This system is based on the combination of PFM–GC × GC with a quadrupole mass spectrometer of GC–MS via a supersonic molecular beams interface and its fly-through Cold EI ion source and applied this system for the analysis of JP8 jet fuel. PFM is ...
DOI:
10.1007/s10337-016-3087-z

75. A New Simple Method for the Evaluation of Mineral Elements in Different Oilseeds

Author:
Silvia Mironeasa; Georgiana Gabriela Codină; Silviu-Gabriel Stroe
Source:
Communications in soil science and plant analysis 2016 v.47 no.15 pp. 1731-1737
ISSN:
1532-2416
Subject:
X-radiation; calcium; copper; flax; iron; linseed; manganese; phosphorus; potassium; pumpkins; seeds; sesame seed; spectral analysis; spectrometers; zinc
Abstract:
... A method for the analysis of seven mineral contents—that is, potassium (K), calcium (Ca), phosphorus (P), iron (Fe), manganese (Mn), zinc (Zn), and copper (Cu)—was investigated in some oilseeds like flax, sesame, pumpkin, quinoa, and yellow mustard. X-ray Spectral Analysis method with Spectrometer EDX-900HS was used for the analytical concentrations of the macro and micro elements of the oilseeds. ...
DOI:
10.1080/00103624.2016.1206914

76. A New Species of Argophyllum (Argophyllaceae) with Notes on the Species from New Caledonia and Nickel Hyperaccumulation

Author:
Yohan Pillon; Vanessa Hequet
Source:
Plants 2021 v.10 no.4 pp. -
ISSN:
2223-7747
Subject:
Argophyllaceae; X-radiation; fluorescence; hyperaccumulators; leaves; lectotypes; new species; nickel; spectrometers; taxonomic keys; New Caledonia
Abstract:
... The taxonomy of Argophyllum (Argophyllaceae) in New Caledonia is reviewed here. All names validly published in Argophyllum in this archipelago are discussed and lectotypified when necessary. A new species is described, Argophyllum riparium (The LSID for the name Argophyllum riparium is: 77216335-1) Pillon and Hequet sp. nov. Argophyllum grunowii and A. ellipticum are both species complexes in whic ...
DOI:
10.3390/plants10040701

77. A New in Situ Method for Tracing Denitrification in Riparian Groundwater

Author:
Andrea L. Popp; Cara C. Manning; Matthias S. Brennwald; Rolf Kipfer
Source:
Environmental science & technology 2020 v.54 no.3 pp. 1562-1572
ISSN:
1520-5851
Subject:
air; denitrification; environmental science; groundwater; models; space and time; spectrometers; technology
Abstract:
... The spatiotemporal dynamics of denitrification in groundwater are still not well-understood because of a lack of efficient methods to quantify this biogeochemical reaction pathway. Previous research used the ratio of N₂ to argon (Ar) to quantify net production of N₂ via denitrification by separating the biologically generated N₂ component from the atmospheric-generated components. However, this me ...
DOI:
10.1021/acs.est.9b05393

78. A Novel Approach To Quantify Air–Water Gas Exchange in Shallow Surface Waters Using High-Resolution Time Series of Dissolved Atmospheric Gases

Author:
Ulrich W. Weber; Peter G. Cook; Matthias S. Brennwald; Rolf Kipfer; Thomas C. Stieglitz
Source:
Environmental science & technology 2018 v.53 no.3 pp. 1463-1470
ISSN:
1520-5851
Subject:
coastal water; dissolved gases; gas exchange; greenhouse gases; liquid-air interface; models; nitrogen; solubility; spectrometers; surface water; time series analysis; water temperature
Abstract:
... Gas exchange across the air–water interface is a key process determining the release of greenhouse gases from surface waters and a fundamental component of gas dynamics in aquatic systems. To experimentally quantify the gas transfer velocity in a wide range of aquatic settings, a novel method based on recently developed techniques for the in situ, near-continuous measurement of dissolved (noble) g ...
DOI:
10.1021/acs.est.8b05318

79. A Novel Insight into the Ozone–Skin Lipid Oxidation Products Observed by Secondary Electrospray Ionization High-Resolution Mass Spectrometry

Author:
Jiafa Zeng; Majda Mekic; Xin Xu; Gwendal Loisel; Zhen Zhou; Sasho Gligorovski; Xue Li
Source:
Environmental science & technology 2020 v.54 no.21 pp. 13478-13487
ISSN:
1520-5851
Subject:
Lewis bases; air; air quality; ammonia; electrospray ionization mass spectrometry; humans; hydroxyl radicals; lipid peroxidation; oxidation; ozone; skin (animal); spectrometers; squalene; technology
Abstract:
... Emissions of secondary products through reactions of oxidants, ozone (O₃), and hydroxyl radical (·OH) with human skin lipids have become increasingly important in indoor environments. Here, we evaluate the secondary organic compounds formed through heterogeneous reactions of gaseous O₃ with hand skin lipids by using a high-resolution quadrupole Orbitrap mass spectrometer coupled to a commercial se ...
DOI:
10.1021/acs.est.0c05100

80. A Novel LC–MS-MS Method With an Effective Antioxidant for the Determination of Edaravone, a Free-Radical Scavenger in Dog Plasma and its Application to a Pharmacokinetic Study

Author:
Feng Shao; Xiao-ling Hu; Xin Liu; Mang-ting Shan
Source:
Journal of chromatographic science 2017 v.55 no.6 pp. 595-602
ISSN:
1945-239X
Subject:
Beagle; acetonitrile; blood plasma; blood sampling; dogs; formic acid; free radical scavengers; intravenous injection; ionization; liquid chromatography; methanol; monitoring; pharmacokinetics; sodium metabisulfite; spectrometers; stabilizers; standard deviation; tandem mass spectrometry
Abstract:
... The objective of this study was to investigate the stability of edaravone in dog plasma by using an added antioxidant stabilizer, with an ultimate goal of developing and validating a sensitive, reliable and robust LC–MS-MS method for determination of edaravone in plasma samples. Edaravone was unstable in plasma, but it presented a good stability performance in the plasma with sodium metabisulfite ...
DOI:
10.1093/chromsci/bmx012

81. A Novel Lipidomics Workflow for Improved Human Plasma Identification and Quantification Using RPLC-MSn Methods and Isotope Dilution Strategies

Author:
Evelyn Rampler; Angela Criscuolo; Martin Zeller; Yasin El Abiead; Harald Schoeny; Gerrit Hermann; Elena Sokol; Ken Cook; David A. Peake; Bernard Delanghe; Gunda Koellensperger
Source:
Analytical chemistry 2018 v.90 no.11 pp. 6494-6501
ISSN:
1520-6882
Subject:
humans; Komagataella pastoris; isotope labeling; spectrometers; yeasts; isomers; lipids; carbon; isotope dilution technique; stable isotopes; mass spectrometry; liquid chromatography
Abstract:
... Lipid identification and quantification are essential objectives in comprehensive lipidomics studies challenged by the high number of lipids, their chemical diversity, and their dynamic range. In this work, we developed a tailored method for profiling and quantification combining (1) isotope dilution, (2) enhanced isomer separation by C30 fused-core reversed-phase material, and (3) parallel Orbitr ...
DOI:
10.1021/acs.analchem.7b05382

82. A Novel Membrane Inlet Mass Spectrometer Method to Measure 15NH4+ for Isotope-Enrichment Experiments in Aquatic Ecosystems

Author:
Yin Guoyu; Hou Lijun; Liu Min; Liu Zhanfei; Gardner Wayne S.
Source:
Environmental Science & Technology 2014 v.48 no.16 pp. 9555-9562
ISSN:
1520-5851
Subject:
aquatic ecosystems; freshwater; iodine; liquid chromatography; mass spectrometry; nitrate reduction; nitrogen; pollution; salinity; sediments; slurries; spectrometers; stable isotopes
Abstract:
... Nitrogen (N) pollution in aquatic ecosystems has attracted much attention over the past decades, but the dynamics of this bioreactive element are difficult to measure in aquatic oxygen-transition environments. Nitrogen-transformation experiments often require measurement of ¹⁵N-ammonium (¹⁵NH₄⁺) ratios in small-volume ¹⁵N-enriched samples. Published methods to determine N isotope ratios of dissolv ...
DOI:
10.1021/es501261s

83. A Novel Method for Unraveling the Black Box of Dissolved Organic Matter in Soils by FT-ICR-MS Coupled with Induction-Based Nanospray Ionization

Author:
Shuchai Gan; Pengran Guo; Ying Wu; Yanping Zhao
Source:
Environmental science & technology letters 2021 v.8 no.4 pp. 356-361
ISSN:
2328-8930
Subject:
agricultural soils; aromatic compounds; carbon; dissolved organic matter; forests; ionization; rivers; soil remediation; solid phase extraction; spectrometers
Abstract:
... Dissolved organic matter (DOM) in soils plays important roles in carbon and nutrient cycling. However, our knowledge of the molecular composition of DOM is limited by selective loss during pretreatment [solid-phase extraction (SPE)] or small amounts of pore water. We proposed a novel method for characterizing DOM by coupling a Fourier transform ion cyclotron resonance mass spectrometer and a self- ...
DOI:
10.1021/acs.estlett.1c00095

84. A Novel Method of Classifying Soil Profiles in the Field using Optical Means

Author:
Eyal Ben-Dor; Daniela Heller; Alexandra Chudnovsky
Source:
Soil Science Society of America journal 2008 v.72 no.4 pp. 1113-1123
ISSN:
0361-5995
Subject:
classification; calibration; subsoil; spectrometers; soil properties; probes (equipment); model validation; spectral analysis; soil profiles; reflectance; statistical models; prediction
Abstract:
... The rationale of this study was to develop a new, objective method for characterizing soil profiles in the field by using the optical means commonly available to most users. For that purpose, we used a field spectrometer (analytical spectral device, ASD) and a specific accessory used to read subsoil reflectance data, together with a multivariate spectral analysis approach. To that end, we develope ...
DOI:
10.2136/sssaj2006.0059

85. A Novel Potential Biomarker on Y263 Site in Human Serum Albumin Poisoned by Six Nerve Agents

Author:
Feiyan Fu; Fengjuan Sun; Xiaogang Lu; Tianyu Song; Junjie Ding; Runli Gao; Hongmei Wang; Chengxin Pei
Source:
Journal of chromatography 2019 v.1104 pp. 168-175
ISSN:
1570-0232
Subject:
binding sites; biomarkers; chemical bonding; human serum albumin; liquid chromatography; molecular dynamics; nerve agents; peptides; spectrometers; tandem mass spectrometry; tyrosine
Abstract:
... Albumin is a new biomarker of organophosphorus compounds (OPs) and nerve agents (OPNAs) for retrospective verification. Recent studies on OPs adducts show that amino acid residues can covalently bind to OPs and OPNAs. In this article, after being incubated with soman, sarin, cyclosarin, VX, ethyl tabun, and propyl tabun, human serum albumin (HSA) is analyzed by quadrupole-Orbitrap mass spectromete ...
DOI:
10.1016/j.jchromb.2018.11.011

86. A Parallel-Column LC–MS/MS Method for High-Throughput Analysis of Eight Antiepileptic Drugs in Clinical Therapeutic Drug Monitoring

Author:
Lei Yin; Meiyun Shi; Tingting Wang; Miaomin Zhang; Xiaojun Zhao; Ying Zhang; Jingkai Gu
Source:
Chromatographia 2017 v.80 no.1 pp. 137-143
ISSN:
0009-5893
Subject:
anticonvulsants; high performance liquid chromatography; humans; monitoring; patients; spectrometers
Abstract:
... Therapeutic drug monitoring (TDM), the practice of measuring drug plasma concentrations at multiple times, is necessary in the clinical management of drugs with narrow therapeutic windows, such as antiepileptic drugs (AEDs). This study describes a parallel two-column LC–MS/MS system for quantitative high-throughput analysis of AEDs in human plasma. It multiplexes two high-performance liquid chroma ...
DOI:
10.1007/s10337-016-3196-8

87. A Performance Comparison of Low-Cost Near-Infrared (NIR) Spectrometers to a Conventional Laboratory Spectrometer for Rapid Biomass Compositional Analysis

Author:
Edward J. Wolfrum; Courtney Payne; Alexa Schwartz; Joshua Jacobs; Robert W. Kressin
Source:
BioEnergy research 2020 v.13 no.4 pp. 1121-1129
ISSN:
1939-1234
Subject:
algorithms; bioenergy; biomass; models; prediction; prototypes; reflectance; spectrometers; wavelengths; Texas
Abstract:
... The performance of a conventional laboratory near-infrared (NIR) spectrometer and two NIR spectrometer prototypes (a Texas Instruments NIRSCAN Nano evaluation model (EVM) and an InnoSpectra NIR-M-R2 spectrometer) are compared by collecting reflectance spectra of 270 well-characterized herbaceous biomass samples, building calibration models using the partial least squares (PLS-2) algorithm to predi ...
DOI:
10.1007/s12155-020-10135-6

88. A Photothermal Spectrometer for Fast and Background-Free Detection of Individual Nanoparticles in Flow

Author:
Maceiczyk Richard; Shimizu Hisashi; Müller David; Kitamori Takehiko; deMello Andrew
Source:
Analytical chemistry 2017 v.89 no.3 pp. 1994-1999
ISSN:
1520-6882
Subject:
gold; interferometry; nanogold; nanoparticles; spectrometers
Abstract:
... Sensitive detection and quantification of individual plasmonic nanoparticles is critical in a range of applications in the biological, nanomaterials, and analytical sciences. Although a wide range of techniques can be applied to the analysis of immobilized particles, high-throughput analysis of nanoscale species in flow is surprisingly underdeveloped. To address this shortcoming, we present an ult ...
DOI:
10.1021/acs.analchem.6b04540

89. A Pilot Study in Humans to Investigate the Relationship Between Circulating L-citrulline and Arginine After Watermelon Intake (rind, Flesh and Seeds) on Endothelial Function (P06-121-19)

Author:
Amandeep Sandhu; Jiayi Fan; Eunyoung Park; Indika Edirisinghe; Britt Burton-Freeman
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
adults; arginine; bioactive compounds; bioavailability; blood sampling; body mass index; cardiovascular diseases; citrulline; clinical trials; endothelium; high performance liquid chromatography; metabolites; nitric oxide; overweight; salads; seeds; spectrometers; ultra-performance liquid chromatography; watermelons
Abstract:
... Endothelial dysfunction is one of the early predictors of cardiovascular disease and proper functioning of the endothelium is dependent upon nitric oxide (NO) bioavailability. Watermelon is a rich source of bioactive components such as L-citrulline and arginine which can increase NO bioavailability directly and indirectly. The objective of this pilot study was to assess the effects of watermelon i ...
DOI:
10.1093/cdn/nzz031.P06-121-19

90. A Pilot Study on the Effect of Short-Term Consumption of a Polyphenol Rich Drink on Biomarkers of Coronary Artery Disease Defined by Urinary Proteomics

Author:
Mullen, W.; Gonzalez, J.; Siwy, J.; Franke, J.; Sattar, N.; Mullan, A.; Roberts, S.; Delles, C.; Mischak, H.; Albalat, A.
Source:
Journal of agricultural and food chemistry 2011 v.59 no.24 pp. 12850–12857
ISSN:
0021-8561
Subject:
biomarkers; capillary electrophoresis; coronary vessels; diet; fibrinogen; immunoglobulin G; overweight; polypeptides; prospective studies; proteome; proteomics; risk; spectrometers; urine
Abstract:
... Polyphenol rich diets have been associated with a reduced risk of cardiovascular disease. We examined the effect of a polyphenol rich (P-R) drink on biomarkers assessed by urinary proteomics. Thirty nine middle aged and overweight subjects were randomized to P-R drink (n = 20) or placebo (n = 19) in addition to their normal diet. After two weeks urine samples were obtained for assessment of the ur ...
DOI:
10.1021/jf203369r
PubMed:
22070129

91. A Poisson nonnegative matrix factorization method with parameter subspace clustering constraint for endmember extraction in hyperspectral imagery

Author:
Weiwei Sun; Jun Ma; Gang Yang; Bo Du; Liangpei Zhang
Source:
ISPRS journal of photogrammetry and remote sensing 2017 v.128 pp. 27-39
ISSN:
0924-2716
Subject:
Bayesian theory; Poisson distribution; algorithms; data collection; hyperspectral imagery; image analysis; models; multipliers; spectrometers; system optimization
Abstract:
... A new Bayesian method named Poisson Nonnegative Matrix Factorization with Parameter Subspace Clustering Constraint (PNMF-PSCC) has been presented to extract endmembers from Hyperspectral Imagery (HSI). First, the method integrates the liner spectral mixture model with the Bayesian framework and it formulates endmember extraction into a Bayesian inference problem. Second, the Parameter Subspace Clu ...
DOI:
10.1016/j.isprsjprs.2017.03.004

92. A Portable Atomic Emission Spectrometer Based on a Drop-Spark Discharge for Analyzing Solutions

Author:
V. V. Yagov; A. S. Korotkov; A. A. Zhirkov; V. I. Pogonin; B. K. Zuev
Source:
Journal of analytical chemistry 2019 v.74 no.3 pp. 270-275
ISSN:
1061-9348
Subject:
atomic absorption spectrometry; chemical analysis; portable equipment; spectrometers
Abstract:
... A portable instrument for analysis of solutions by atomic emission spectrometry is described based on recording the emission spectrum of a drop-spark discharge using a Maya 2000 Pro spectrometer (Ocean Optics, United States). ...
DOI:
10.1134/S1061934819030122

93. A Portable and Autonomous Mass Spectrometric System for On-Site Environmental Gas Analysis

Author:
Brennwald Matthias S.; Schmidt Mark; Oser Julian; Kipfer Rolf
Source:
Environmental Science & Technology 2016 v.50 no.24 pp. 13455-13463
ISSN:
1520-5851
Subject:
carbon dioxide; contractors; energy use and consumption; gas exchange; gases; lakes; mass spectrometry; methane; nitrogen; oxygen; spectrometers; superoxide anion; uncertainty
Abstract:
... We developed a portable mass spectrometric system (“miniRuedi”) for quantificaton of the partial pressures of He, Ne (in dry gas), Ar, Kr, N₂, O₂, CO₂, and CH₄ in gaseous and aqueous matrices in environmental systems with an analytical uncertainty of 1–3%. The miniRuedi does not require any purification or other preparation of the sampled gases and therefore allows maintenance-free and autonomous ...
DOI:
10.1021/acs.est.6b03669

94. A Preliminary Investigation on Metal Bioaccumulation by Perenniporia fraxinea

Author:
M. Sturini; C. Girometta; F. Maraschi; E. Savino; A. Profumo
Source:
Bulletin of environmental contamination and toxicology 2017 v.98 no.4 pp. 508-512
ISSN:
0007-4861
Subject:
Aesculus; Fomes fraxinophilus; bioaccumulation; cadmium; chromium; copper; culture media; environmental monitoring; fungi; heavy metals; iron; lead; manganese; mercury; nickel; ornamental plants; pathogens; pollution; spectrometers; spectroscopy; suburban areas; zinc; Italy
Abstract:
... The lignicolous macrofungus Perenniporia fraxinea has drawn increased attention due to its role as a pathogen of ornamentals in urban sites. The present study investigated the bioaccumulation of heavy metals by P. fraxinea. Sporophores were collected from urban and suburban areas in Pavia (Northern Italy) and analyzed for metals content (Cd, Hg, Pb, Ni, Cr, Cu, Fe, Mn, Zn) by inductively coupled p ...
DOI:
10.1007/s00128-017-2038-1

95. A Proteomic Approach To Investigate the Distribution and Abundance of Surface and Internal Fasciola hepatica Proteins during the Chronic Stage of Natural Liver Fluke Infection in Cattle

Author:
Haçarız Orçun; Sayers Gearóid; Baykal Ahmet Tarık
Source:
Journal of Proteome Research 2012 v.11 no.7 pp. 3592-3604
ISSN:
1535-3907
Subject:
Fasciola hepatica; Homo sapiens; Mus musculus; Xenopus tropicalis; cattle; cholesterol acyltransferase; fascioliasis; high performance liquid chromatography; integrins; ionization; liver flukes; proteome; proteomics; spectrometers; surface proteins; vaccines
Abstract:
... Fasciola hepatica, a trematode helminth, causes an economically important disease (fasciolosis) in ruminants worldwide. Proteomic analysis of the parasite provides valuable information to understand the relationship between the parasite and its host. Previous studies have identified various parasite proteins, some of which are considered as vaccine candidates or important drug targets. However, th ...
DOI:
10.1021/pr300015p

96. A Prototype Evanescent Wave-Coupled Cavity Ring-down Spectrometer for Probing Real-Time Aggregation Kinetics of Gold and Silver Nanoparticles

Author:
Sanchi Maithani; Abhijit Maity; Manik Pradhan
Source:
Analytical chemistry 2020 v.92 no.5 pp. 3998-4005
ISSN:
1520-6882
Subject:
absorbance; diodes; geometry; gold; image analysis; nanogold; nanoparticles; nanosilver; prototypes; silver; spectrometers; spectroscopy
Abstract:
... We report on the development of a simple, linear optical cavity-based system combining evanescent wave (EW) with high-sensitive cavity ring-down spectroscopy (CRDS) technique using a diode laser at 644 nm and a right-angled prism for evanescent field generation on prism surface. We characterized the setup in detail and achieved an optimum ring-down time of 159.4 ns and a minimum absorption coeffic ...
DOI:
10.1021/acs.analchem.9b05521

97. A Pulsed Atomization and Excitation Source of Variable Discharge Gap Geometry in the Analysis of Solutions by Atomic Emission Spectrometry

Author:
B. K. Zuev; A. A. Zhirkov; V. V. Yagov; I. S. Smirnova; A. S. Korotkov
Source:
Journal of analytical chemistry 2020 v.75 no.9 pp. 1143-1146
ISSN:
1061-9348
Subject:
analytical chemistry; anodes; atomic absorption spectrometry; atomization; geometry; spectrometers
Abstract:
... An atomization and excitation source for the analysis of solutions by atomic emission spectrometry is proposed on the basis of pulsed glow discharge with a solid anode and discharge gap geometry varied within the discharge. A portable atomic emission spectrometer recording total emission spectrum from a single sample drop is developed in its basis. ...
DOI:
10.1134/S1061934820090178

98. A Quasielastic Neutron Scattering Study of Water Diffusion in Model Anion Exchange Membranes over Localized and Extended Volume Increments

Author:
Jan-Patrick Melchior; Niina H. Jalarvo
Source:
Journal of physical chemistry 2019 v.123 no.23 pp. 14195-14206
ISSN:
1932-7455
Subject:
anion-exchange membranes; anions; cost effectiveness; diffusivity; electrochemistry; energy conversion; fuel cells; models; neutron diffraction; physical chemistry; polymers; spectrometers
Abstract:
... Anion exchange membranes provide the basis for potentially more cost-effective fuel cells, electrochemical energy conversion, and energy storage. The membranes consist of a polymer domain with tethered cationic side groups and a pervading aqueous domain that conducts water and anions. Water diffusion is investigated through temperature-dependent quasielastic neutron scattering (QENS) at applicatio ...
DOI:
10.1021/acs.jpcc.9b01873

99. A Rapid Method for Analyzing Synthetic Phenolic Antioxidants in Food Grade Lubricant Samples Based on Headspace Solid-Phase Microextracion Coupled with Gas Chromatography-Mass Spectrometer

Author:
Yiwei Chen; Yijun Zhang; Li Xu
Source:
Food analytical methods 2021 v.14 no.12 pp. 2524-2533
ISSN:
1936-9751
Subject:
butylated hydroxytoluene; detection limit; headspace analysis; lubricants; maximum residue limits; pH; rapid methods; spectrometers; temperature
Abstract:
... This article is focused on the effectiveness of headspace solid-phase micro-extraction (HS-SPME) for determining 4 synthetic phenolic antioxidants (SPAs, including 2,6-di-tert-butylphenol, 4-tert-butylphenol, 2,4-Di-tert-butylphenol, and butylated hydroxytoluene) in food-grade lubricant samples. The effectiveness of 4 fibre types was compared. 50/30μm DVB/Carboxen/PDMS was found to be the most sui ...
DOI:
10.1007/s12161-021-02053-w

100. A Rapid Sample Preparation Procedure Using MonoSpin CBA and Amide Columns for Tetrodotoxin Detection in Serum and Urine Using LC–MS/MS Analysis

Author:
Takeshi Saito; Naoya Miura; Akira Namera; Shigenori Ota; Shota Miyazaki; Sadaki Inokuchi
Source:
Chromatographia 2014 v.77 no.9-10 pp. 687-693
ISSN:
0009-5893
Subject:
acetic acid; acetonitrile; blood serum; detection limit; fish; formic acid; high performance liquid chromatography; immunoassays; ionization; monitoring; patients; poisoning; screening; spectrometers; tetrodotoxin; urine
Abstract:
... Clinical diagnosis of tetrodotoxin (TTX) poisoning can be difficult because of the lack of characteristic morphological findings and a screening test, such as an immunoassay. Here, we present a fully validated method for the analysis of TTX in serum and urine. In this method, serum and urine samples were extracted using MonoSpin CBA or amide columns, followed by LC–MS/MS analysis. The TTX was elut ...
DOI:
10.1007/s10337-014-2663-3