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- Schafer, Simon T., et al. Show all 3 Authors
- Cell 2016
- adulthood; adults; hippocampus; mammals; memory; neonates; neurogenesis; neurons; stem cells
- ... The dentate gyrus of the mammalian hippocampus continuously generates new neurons during adulthood. These adult-born neurons become functionally active and are thought to contribute to learning and memory, especially during their maturation phase, when they have extraordinary plasticity. In this Review, we discuss the molecular machinery involved in the generation of new neurons from a pool of adu ...
- Schäfer, Karl-Herbert, et al. Show all 6 Authors
- Cell and tissue research 2014 v.355 no.1 pp. 35-48
- central nervous system; digestive system; food intake; immune system; inflammation; mice; neurons; stem cells; toxins
- ... The enteric nervous system (ENS) controls and modulates gut motility and responds to food intake and to internal and external stimuli such as toxins or inflammation. Its plasticity is maintained throughout life by neural progenitor cells within the enteric stem cell niche. Granulocyte-colony stimulating factor (G-CSF) is known to act not only on cells of the immune system but also on neurons and n ...