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1. RNA sequencing analysis of transcriptional change in the freshwater mussel Elliptio complanata after environmentally relevant sodium chloride exposure

Author:
Robertson, Laura S.; Galbraith, Heather S.; Iwanowicz, Deborah; Blakeslee, Carrie J.; Cornman, R. Scott
Source:
Environmental toxicology and chemistry 2017 v.36 no.9 pp. 2352-2366
ISSN:
0730-7268
Subject:
Bivalvia; RNA; adenosine; adults; amino acid metabolism; aquaporins; biomarkers; cluster analysis; freshwater; freshwater mussels; gene expression regulation; genes; heat-shock protein 70; indicator species; osmotic stress; potassium; protein folding; quantitative polymerase chain reaction; salt stress; sequence analysis; sodium chloride; stress response; taurine; transcription (genetics); transporters
Abstract:
... To identify potential biomarkers of salt stress in a freshwater sentinel species, we examined transcriptional responses of the common mussel Elliptio complanata to controlled sodium chloride (NaCl) exposures. Ribonucleic acid sequencing (RNA‐Seq) of mantle tissue identified 481 transcripts differentially expressed in adult mussels exposed to 2 ppt NaCl (1.2 ppt chloride) for 7 d, of which 290 had ...
DOI:
10.1002/etc.3774

2. Adenosine receptor agonists affect taurine release from mouse brain stem slices in ischemia

Author:
Saransaari, Pirjo; Oja, Simo S.
Source:
Amino acids 2010 v.38 no.5 pp. 1387-1393
ISSN:
0939-4451
Subject:
adenosine; adults; agonists; antagonists; brain stem; ischemia; mice; normoxia; purinergic receptors; taurine; tritium
Abstract:
... The release of the inhibitory amino acid taurine is markedly enhanced under ischemic conditions in both adult and developing brain stem, together with a pronounced increase in the release of the neuromodulator adenosine. We now studied the effects of adenosine receptor agonists and antagonists on [³H]taurine release in the brain stem in normoxia and ischemia, using a superfusion system. Under stan ...
DOI:
10.1007/s00726-009-0351-7
PubMed:
19768520

3. Characteristics of taurine release induced by free radicals in mouse hippocampal slices

Author:
Saransaari, P.; Oja, S. S.
Source:
Amino acids 2004 v.26 no.1 pp. 91-98
ISSN:
0939-4451
Subject:
adenosine; adults; agonists; antagonists; cell membranes; glutamic acid; hippocampus; hydrogen peroxide; hydroxylamine; ischemia; mice; neuroprotective effect; nitric oxide; receptors; taurine; transporters; tritium
Abstract:
... The release of the inhibitory neuromodulator taurine in the hippocampus is markedly enhanced under various neural cell-damaging conditions, including ischemia and exposure to free radicals. The properties and regulation of the release evoked by a medium containing free radicals was investigated in hippocampal slices from adult (3-month-old) and developing (7-day-old) mice, using a superfusion syst ...
DOI:
10.1007/s00726-003-0004-1