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- Lee, Seongsoo, et al. Show all 11 Authors
- International journal of biological macromolecules 2017 v.97 pp. 181-189
- biomarkers; cell death; chlorins; dextran; dialysis; drugs; endocytosis; fluorescence; hydrophobic bonding; image analysis; in vitro studies; inflammation; irradiation; lipopolysaccharides; macrophages; nanoparticles; receptors; singlet oxygen; spectrophotometers; therapeutics; transmission electron microscopes
- ... Scavenger receptors (SRs) expressed on the activated macrophages in inflammation sites have been considered as the most interesting and important target biomarker for targeted drug delivery, imaging and therapy. In the present study, we fabricated the scavenger receptor-A (SR-A) targeted-photoactivatable nanoagents (termed as Ce6/DS-DOCA) by entrapping chlorin e6 (Ce6) into the amphiphilic dextran ...
- Lee, Seongsoo, et al. Show all 6 Authors
- Biochemical and biophysical research communications 2019 v.513 no.4 pp. 925-932
- Alzheimer disease; Parkinson disease; amyotrophic lateral sclerosis; autophagy; death; enzymes; neurons; protein aggregates; therapeutics; toxicity
- ... The most prominent hallmarks of many neurodegenerative diseases are the accumulation of misfolded protein aggregates and the death of certain neuronal populations. Autophagy is the major intracellular mechanism that degrades protein aggregates and damaged cellular components. Many studies have reported that the dysfunction of autophagy is associated with several neurodegenerative diseases, such as ...