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bitumen; economic resources; energy industry; oils; petroleum; remediation; toxicity; Alberta; China
Abstract:
... The oil sands in Northern Alberta are the largest oil sands in the world, providing an important economic resource for the Canadian energy industry. The extraction of petroleum in the oil sands begins with the addition of hot water to the bituminous sediment, generating oil sands process-affected water (OSPW), which is acutely toxic to organisms. Trillions of litres of OSPW are stored on oil sands ...
absorption; cadmium; heavy metals; hydroponics; mass spectrometry; pollutants; pollution; rice; root growth; root tips; stele; tetracycline; tillering; toxicity; transportation; China
Abstract:
... Co-exposure to heavy metal and antibiotic pollution might result in complexation and synergistic interactions, affecting rice growth and further exacerbating pollutant enrichment. Therefore, our study sought to clarify the influence of different Tetracycline (TC) and Cadmium(Cd) concentration ratios (both alone and combined) on rice growth, pollutant accumulation, and transportation during the til ...
... Copper (Cu) is a kind of micronutrient element that is essential for human metabolism. However, it is also considered as an environmental pollutant which is toxic to organisms at a high concentration level. Probiotics, regarded as beneficial microorganisms for promoting human health, have functions of antioxidant capacity, immune-enhancing properties, intestinal barrier protection and regulation. ...
DNA; Western blotting; ammonia; animal models; apoptosis; dose response; epithelium; genes; inflammation; lungs; metabolome; mineral fertilizers; oxidative phosphorylation; oxidative stress; protein synthesis; pyruvic acid; swine; toxicity; transcriptome; transmission electron microscopy; China
Abstract:
... Ammonia, a common toxic gas, is not only one of the main causes of haze, but also can enter respiratory tract and directly affect the health of humans and animals. Pig was used as an animal model for exploring the molecular mechanism and dose effect of ammonia toxicity to lung. In this study, the apoptosis of type II alveolar epithelial cells was observed in high ammonia exposure group using trans ...
... The concentrations and distributions of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) in the whole blood and meat of eight typical edible animals (chicken, donkey, horse, cattle, rabbit, sheep, duck, and pig) were illustrated. Total concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and PCBs (on a ...
bioaccumulation; biphenyl; bromination; electron transfer; environmental fate; hydrogen; mechanochemistry; photocatalysis; photolysis; thermodynamics; toxicity; China
Abstract:
... Polybrominated diphenyl ethers (PBDEs) are widely used as brominated flame retardants, which had attracted amounts of attention due to their harmful characteristics of high toxicity, environmental persistence and potential bioaccumulation. Many chemical reductive debromination technologies have been developed for the debromination of PBDEs, including photolysis, photocatalysis, electrocatalysis, z ...
... Hazardous waste of chemical oxygen demand (COD) test (HWCOD) is one of the most common laboratory wastewaters, containing large amounts of H₂SO₄ and highly toxic Cr³⁺ and Hg²⁺. Current treatment methods suffered from incomplete removal of Cr³⁺ and high-cost. Herein, a humic acid-coated zirconium oxide-resin nanocomposite (HA-HZO-201) was fabricated for efficient recovery of Cr³⁺ and Hg²⁺ in HWCOD. ...
... Lactose is a disaccharide and has many uses in food and non-food formulations. Its anomeric form, β-lactose, is a natural inhibitor of the galectin-3 protein, which is responsible for several pathological effects (e.g., colon cancer cell proliferation). However, lactose cannot be orally administered since it is rapidly hydrolyzed by intestinal lactases. Therefore, the development of nanosystems fr ...
ammonium; anodes; chlorine; electrocoagulation; oxidation; oxygen; phenanthrenes; phosphorus; remediation; total organic carbon; toxicity; China
Abstract:
... In situ and simultaneous remediation of a variety of pollutants in sediments remains a challenge. In this study, we report that the combination of electrocoagulation (EC) and electrooxidation (EO) is efficient in the immobilization of phosphorus and heavy metals and in the oxidation of ammonium and toxic organic matter. The integrated mixed metal oxide (MMO)/Fe anode system allowed the facile remo ...
... Microcystin-leucine-arginine (MC-LR) is positively linked with multiple cancers in humans. However, the association between MC-LR and the risk and prognosis of prostate cancer has not been conducted in epidemiological studies. No reported studies have linked MC-LR exposure to the poor prognosis of prostate cancer by conducting experimental studies. The content of MC-LR was detected in most of the ...
... Biogenic hydrogen sulfide is an odorous, toxic and corrosive gas released from sewage in sewers. To control sulfide generation and emission, nitrate is extensively applied in sewer systems for decades. However, the unexpected sulfide rebound after nitrate addition is being questioned in recent studies. Possible reasons for the sulfide rebounds have been studied, but the mechanism is still unclear, ...
Fourier transform infrared spectroscopy; absorption; adsorption; glyphosate; human health; pH; photocatalysts; photolysis; toxicity; China
Abstract:
... With increasing concerns on the environment and human health, the degradation of glyphosate through the formation of less toxic intermediates is of great importance. Among the developed methods for the degradation of glyphosate, photodegradation is a clean and efficient strategy. In this work, we report a new photocatalyst by doping F ion on BiVO₄ that can efficiently degrade glyphosate and reduce ...
carbon nitride; coordination polymers; detection limit; fluorescence; graphene; heavy metals; human health; mercury; quantum dots; semiconductors; spectroscopy; surface area; toxicity; China
Abstract:
... The presence of toxic mercury (II) in water is an ever-growing problem on earth that has various harmful effect on human health and aquatic living organisms. Therefore, detection of mercury (II) in water is very much crucial and several researches are going on in this topic. Metal-organic frameworks (MOFs) are considered as an effective device for sensing of toxic heavy metal ions in water. The tu ...
Japan; activated sludge; biodegradation; biological treatment; biotransformation; databases; metrology; nitrogen; phosphorus; toxicity; wastewater; water reuse; water treatment; China
Abstract:
... In order to reveal the hotspots and trends of biological water treatment from the perspectives of scientific and technological innovation, both of the bibliometric review and patents analysis were performed in this study. The Web of Science Core Collection database and Derwent Innovation Index database recorded 30023 SCI papers and 50326 patents, respectively were analyzed via information visualiz ...
adsorption; antimony; bioavailability; groundwater; hot water treatment; ion exchange; polluted soils; remediation; risk; sorption isotherms; toxicity; China
Abstract:
... Sb(III) is often detected in contaminated soil and groundwater. Hence, high-efficiency technology is needed. In this study, bimetallic organic frameworks were used for the first time to immobilize Sb(III) from contaminated soil and groundwater. The materials were synthesized by the hydrothermal method. Both ends of the prepared material were hexagonal tip rods, and the length became shorter as the ...
Fourier transform infrared spectroscopy; X-ray photoelectron spectroscopy; activated sludge; antibiotics; biodegradation; biopolymers; density functional theory; fluorescence; nitrogen; nuclear magnetic resonance spectroscopy; toxicity; trimethoprim; tryptophan; wastewater; wastewater treatment; China
Abstract:
... Soluble microbial products (SMPs), dissolved organic matter excreted by activated sludge, can interact with antibiotics in wastewater and natural water bodies. Interactions between SMPs and antibiotics can influence antibiotic migration, transformation, and toxicity but the mechanisms involved in such interactions are not fully understood. In this study, integrated spectroscopy approaches were use ...
... Vacuum ultraviolet (VUV) photolysis is recognized as an environmental-friendly treatment process. Nitrate (NO₃⁻) and natural organic matter (NOM) are widely present in water source. We investigated trichloronitromethane (TCNM) formation during chlorination after VUV photolysis, because TCNM is an unregulated highly toxic disinfection byproduct. In this study: (1) we found reactive nitrogen species ...
Danio rerio; agonists; antagonists; bioassays; calcium; cardiomyocytes; cardiotoxicity; electron transport chain; gene expression; heart rate; human health; mepanipyrim; mitochondria; toxicity; viticulture; China
Abstract:
... The wide use of pesticides has seriously threatened human health and the survival of beneficial organisms. The fungicide mepanipyrim is widely used in viticulture practices. Studies of mepanipyrim-induced toxicity in organisms are still scarce, especially studies on cardiotoxicity. In this study, we aimed to investigate mepanipyrim-induced cardiotoxicity in zebrafish (Danio rerio) larvae. We found ...
DNA replication; Selenastrum capricornutum; algae; biosynthesis; energy metabolism; erythromycin; fatty acids; growth performance; growth promotion; growth retardation; hormesis; metabolomics; nucleosides; ribosomes; toxicity; transcription (genetics); xenobiotics; China
Abstract:
... A recent study showed that erythromycin (ERY) exposure caused hormesis in a model alga (Raphidocelis subcapitata) where the growth was promoted at an environmentally realistic concentration (4 μg/L) but inhibited at two higher concentrations (80 and 120 μg/L), associated with opposite actions of certain signaling pathways (e.g., xenobiotic metabolism, DNA replication). However, these transcription ...
... The widely use of silver nanoparticles (AgNPs) as antimicrobial agents gives rise to potential environmental risks. AgNPs exposure have been reported to cause toxicity in animals. Nevertheless, the known mechanisms of AgNPs toxicity are still limited. In this study, we systematically investigated the toxicity of AgNPs exposure using Drosophila melanogaster. We show here that AgNPs significantly de ...
... Organophosphates (OPs) are an integral part of modern agriculture; however, due to overexploitation, OPs pesticides residues are leaching and accumulating in the soil, and groundwater contaminated terrestrial and aquatic food webs. Acute exposure to OPs could produce toxicity in insects, plants, animals, and humans. OPs are known for covalent inhibition of acetylcholinesterase enzyme in pests and ...
Danio rerio; adults; bioaccumulation; brain; chemical analysis; flame retardants; histopathology; humans; liver; pollution; progeny; toxicity; transcription (genetics); China
Abstract:
... Many environmental contaminants could be transmitted from parents and generate impairments to their progeny. The 2,4,6-tribromophenol (TBP), a novel brominated flame retardant which has been frequently detected in various organisms, was supposed to be bioaccumulated and intergenerational transmitted in human beings. Previous studies revealed that TBP could disrupt thyroid endocrine system in zebra ...
... The wastewater discharge from the process of chrome plating, which contains 6:2 chlorinated polyfluorinated ether sulfonate (F-53B) and chromium (Cr), may be toxic to biofilm. In this study we found that the biofilm formed by Pseudomonas aeruginosa PAO1 was inhibited by exposure to a combination of F-53B and Cr(VI). The combined pollution damaged the cell membranes and the structure of the biofilm ...
Nitrosospira; ammonia; arsenic; bioavailability; community structure; genes; humans; nitrogen; oxidation; phylogeny; quantitative polymerase chain reaction; restriction fragment length polymorphism; toxicity; China
Abstract:
... Soil arsenic contamination is of great concern because of its toxicity to human, crops, and soil microorganisms. However, the impacts of arsenic on soil ammonia oxidizers communities remain unclear. Seven types of soil spiked with 0 or 100 mg arsenic per kg soil were incubated for 180 days and sampled at days 1, 15, 30, 90 and 180. The changes in the community composition and abundance of ammonia ...
bioaccumulation; cadmium; cultivars; hydroponics; oxidative stress; phytoremediation; rice; saline soils; salinity; salt stress; salt tolerance; sustainable agriculture; synergism; toxicity; China
Abstract:
... Salt-tolerant rice (sea rice) is a key cultivar for increasing rice yields in salinity soil. The co-existence of salinity and cadmium (Cd) toxicities in the plant-soil system has become a great challenge for sustainable agriculture, especially in some estuaries and coastal areas. However, little information is available on the Cd accumulating features of sea rice under the co-stress of Cd and sali ...
adsorbents; adsorption; chromium; ecosystems; formic acid; heavy metals; human health; pH; pollution; porosity; surface area; toxicity; wastewater; water quality; China
Abstract:
... Zr-based metal-organic frameworks (MOFs) have been developed in recent years to treat heavy metals, e.g. hexavalent chromium Cr⁶⁺ pollution, which damages the surrounding ecosystem and threaten human health. This kind of MOF is stable and convenient to prepare, but has the disadvantage of low adsorption capacity, limiting its wide application. To this end, a novel formic acid and amino modified MO ...
agricultural soils; corn; data collection; food safety; human health; irrigation; models; pollution; prediction; risk; risk assessment; sewage; soil pH; toxicity; wheat; China; Yellow River
Abstract:
... Cadmium (Cd) pollution of agricultural soil is of public concern due to its high potential toxicity and mobility. This study aimed to reveal the risk of Cd accumulation in soil and wheat/maize systems, with a specific focus on the source-specific ecological risk, human health risk and Cd enrichment model. For this we investigated more than 6100 paired soil and grain samples with 216 datasets inclu ...
Danio rerio; cadmium; calcium; dose response; gene expression regulation; heavy metals; lipid metabolism; remission; toxicity; toxicology; transcriptome; water hardness; China
Abstract:
... Cadmium (Cd), a ubiquitous environmental hazardous heavy metal, poses a significant threat to the health of aquatic organisms, including teleosts. Although the toxic profile of Cd is well recognized, little is known regarding the overall view of toxic responses to varying aquatic environmental parameters (e.g., water hardness) at an individual level. Herein, differences in water hardness were part ...
Jiezhang Mo; Miles Teng Wan; Doris Wai-Ting Au; Jingchun Shi; Nathan Tam; Xian Qin; Napo K.M. Cheung; Keng Po Lai; Christoph Winkler; Richard Yuen-Chong Kong; Frauke Seemann
Oryzias latipes; ancestry; biomarkers; bone formation; bone morphogenetic proteins; bone resorption; environmental health; epigenetics; histones; males; microRNA; osteoblasts; osteoclasts; oxidative stress; pollutants; progeny; stress response; toxicity; transcriptome; transcriptomics; wild fish; China
Abstract:
... Benzo[a]pyrene (BaP), a ubiquitous pollutant, raises environmental health concerns due to induction of bone toxicity in the unexposed offspring. Exposure of F0 ancestor medaka (Oryzias latipes) to 1 μg/L BaP for 21 days causes reduced vertebral bone thickness in the unexposed F3 male offspring. To reveal the inherited modifications, osteoblast (OB) abundance and molecular signaling pathways of tra ...
... Exposure to triclosan (TCS) has been reported to reduce photosynthetic pigments, suppress photosynthesis, and inhibit growth in both prokaryotic and eukaryotic algae including Anabaena flos-aquae (a model cyanobacterium). In particular, cyanobacteria are more sensitive to TCS toxicity compared to eukaryotic algae possibly due to the structural similarity to bacteria (target organisms); however, wh ...
... To protect the wellbeing of research animals, certain non-invasive measures are in increasing need to facilitate an early diagnosis of health and toxicity. In this study, feces specimen was collected from adult zebrafish to profile the metabolome fingerprint. Variability in fecal metabolite composition was also distinguished as a result of aging, perfluorobutanesulfonate (PFBS) toxicant, and fecal ...
Corbicula fluminea; hormesis; mortality; oxidative stress; remediation; risk; toxicity; China
Abstract:
... Metal-organic frameworks (MOFs) are promising new materials that have been intensively studied and possibly applied to various environmental remediation. However, little is known about the fate and risk of MOFs to living organisms in the water environment. Here, the toxic effects of ZIF-8 nanoparticles (NPs) on benthic organisms were confirmed by sub-chronic toxicity experiments (7 and 14 days) us ...
biphenyl; bromination; cations; hydrogen; hydrophobicity; ligands; risk assessment; toxicity; van der Waals forces; wastewater treatment; China
Abstract:
... This review focuses on the occurrence and interactions of engineered nanoparticles (ENPs) and brominated flame retardants (BFRs) such as polybrominated diphenyl ethers (PBDEs) in water systems and the generation of highly complex compounds in the environment. The release of ENPs and BFRs (e.g. PBDEs) to aquatic environments during their usage and disposal are summarised together with their key int ...
... Background: Despite recent advances in the treatment of squamous cell skin cancer (SCSC), the disease persists, and treatment resistance develops. Thus, identifying new targets and developing new therapeutic approaches showing low vulnerability to drug resistance is highly needed. Purpose: This study aimed to reveal a novel targeted phytotherapeutic strategy for SCSC treatment alone or in combinat ...
... Electric scooters become popular in Western cities as new mobility option. Start-up companies rent out e-scooters in major cities, such as Paris, Cologne, Copenhagen and elsewhere. However, the scooters are frequently vandalized and thrown into surface waters. There is concern about a new kind of water pollution from leaking scooter batteries. Two scooter batteries (lithium ion type) were dumped i ...
consumer demand; dietary recommendations; grapes; green tea; human health; ingestion; markets; metabolites; oral administration; phytotherapy; research; toxicity; traditional foods
Abstract:
... Fruit‐ and vegetable‐derived (poly)phenols are secondary plant metabolites that may have beneficial effects on human health when consumed regularly. Recent years have seen rapid growth in both consumer demand for and research interest in (poly)phenol‐rich dietary supplements, natural colorants, and functional foods. As these products continue to enter the marketplace and (poly)phenol intake patter ...
Ana P.R. Santana; Patricia de Andrade Nascimento; Taciana G.S. Guimarães; Iohanna M.N. Ribeiro Menezes; Daniel F. Andrade; Andrea Oliveira; Mario H. Gonzalez
... Currently, there is a huge demand for the development of analytical methods for chemical analysis. Sustainable methods have aroused the interest of researchers in the last years. This paper reviews important technologies for digestion and solid-liquid extraction approaches, with emphasis in emerging greener methods for the elemental analysis of different samples. Analytical technologies such as Mi ...
irradiation; lighting; photocatalysis; solar radiation; tetracycline; toxicity
Abstract:
... Developing synergistic systems and taking environmental risks into account are two necessary aspects of being considered to remove persistent organic pollutants efficiently. Thus, a combined catalytic system uniting the Fenton-like process and simulated solar-light photocatalysis has been constructed. Moreover, a series of NiCo₂O₄/HP-UiO-66 catalysts (yNiCo-DUx) were also fabricated to improve tet ...
acrylates; electrochemistry; energy; energy density; gasoline; gels; glycerol; green chemistry; isomers; liquids; lithium; plasticizers; polymers; solubility; solvents; toxicity
Abstract:
... Li–O₂ batteries are actively being investigated due to their high theoretical energy density (∼11 000 Wh kg⁻¹), which would compete with gasoline energy per Kg in electric vehicles. Linear glymes are the most appealing electrolytes for Li–O₂ batteries due to their large electrochemical window, stability against radicals and solubility of Li⁺ metal ions. However, all these superior properties are t ...
... Aliphatic aldehydes are toxic substances that correlate with the onset of many diseases. However, up to date, the methods to identify aliphatic aldehydes in biological samples are less selectivity and/or robustness. In this study, a strategy based on 2,4-dinitrophenylhydrazine (DNPH) capturing combined with mass defect filtering (MDF) was established and validated to identify aliphatic aldehydes i ...
... The development of safer and more sustainable solvents is an important discipline in the context of stricter regulations and environmental protection. This work demonstrates the sustainable synthesis of a potentially bio-based, inherently nonperoxide-forming ether solvent, namely, 2,5-diethyl-2,5-dimethyloxolane (DEDMO), in quantitative yields with high atom economy (97%) and reaction mass efficie ...
... Halobenzoquinones are frequently detected as disinfection by-products in drinking water. Among identified halobenzoquinones, 2,6-dichloro-1,4-benzoquinone (2,6-DCBQ) is particularly toxic and is frequently detected in drinking water. Synthetic aromatic antioxidants discharged to source water may increase the risk of 2,6-DCBQ formation, as many studies suggest that aromatic compounds are the most l ...
... Colorectal cancer (CRC) has a high morbidity and mortality worldwide. 20 (S)-ginsenoside Rh2 (G-Rh2) is a natural compound extracted from ginseng, which exhibits anticancer effects in many cancer types. In this study, we demonstrated the effect and underlying molecular mechanism of G-Rh2 in CRC cells in vitro and in vivo. Cell proliferation, migration, invasion, apoptosis, cell cycle, and western ...
... The steam‑oxygen gasification process of solid recovered fuel (SRF) was proved as a promising approach for energy and resource sustainability through a comprehensive product analysis. A high content of syngas was produced and suitable for the downstream chemical synthesis and hydrogen energy source. However, tar is a significant hazardous mixture from waste gasification, resulting in low gasificat ...
... Nitrophenols(NPs) are highly toxic compounds that occur in various industrial effluents. Herein, we investigated Cu nanoparticle-loaded cellulose nanofibril (CNF/PEI-Cu) aerogels as a catalyst for degrading 4-nitrophenol (4NP) in the wastewater. Non-noble metal based low-cost catalyst material and easily scalable preparation method make CNF/PEI-Cu aerogel as an appropriate catalyst for practical a ...
Imran Ali; Juying Li; Changsheng Peng; Muhammad Qasim; Zahid M. Khan; Iffat Naz; Muhammad Sultan; Muhammad Rauf; Waheed Iqbal; Hafiz Muhammad Adeel Sharif
... Recently, 3-dimensional membrane capsules (3-D MCs) have attracted great attention and have been frequently utilized for removal of the environmental pollutants due to their plentiful oxygen-containing/hydrophilic functional groups, wide operational pH range, desired morphology and higher selectivity against targeted contaminants. Moreover, potentially toxic metals and refractory organic pollutant ...
Fourier transform infrared spectroscopy; X-ray diffraction; adsorption; cost effectiveness; electrostatic interactions; field experimentation; fly ash; food production; food safety; hot water treatment; human health; ion exchange; lead; microstructure; paddy soils; polluted soils; pollution; remediation; rice; silicates; spectrometers; toxicity
Abstract:
... Lead (Pb) is a toxic metal in industrial production, which can seriously threat to human health and food safety. Thus, it is particularly crucial to reduce the content of Pb in the environment. In this study, raw fly ash (FA) was used to synthesise a new active silicate materials (IM) employing the low-temperature-assisted alkali (NaOH) roasting approach. The IM was further synthesised to form zeo ...
... A new protein detector of 2,4,6-trinitrophenol (TNP, picric acid) is concisely reported herein for the first time. In brief, the gene of a specific scFv fragment, namely 3.5, was fused separately with the gene of β-lactamase and, subsequently, expressed in the periplasmic space of Escherichia coli, affording in such a way the recombinant fusion protein 3.5-scFv-β-lactamase. This bifunctional immun ...
analytical chemistry; detection limit; electron transfer; fluorescence; fluorescent dyes; hydrophobicity; mass transfer; polymers; porous media; surface area; technetium; toxicity; wastewater
Abstract:
... Technetium (⁹⁹Tc) is a highly toxic radioactive nuclear wastewater contaminant. Real-time detection of ⁹⁹Tc is very difficult due to its difficult-to-complex nature. Herein, a novel three-dimensional ionic olefin-linked conjugated microporous polymer (TFPM-EP-Br) is constructed using tetrakis(4-aldehyde phenyl)methane (TFPM) as the central monomer. The unique cationic cavity and highly hydrophobic ...
... Three-dimensional printing can be successfully applied in the food sector to fabricate 3D foods with complex geometries, customized texture, and tailored nutritional contents. The concrete application of 3D printing to foods began in the early 2000 s. This work is aimed to provide a comprehensive overview of 3D printed foods. Details and issues concerning ingredients and technologies available for ...
... Scaffolds suitable for use in food products are crucial components for the production of cultured meat. Here, wheat glutenin, an inexpensive and abundant plant-based protein, was used to develop 3D porous scaffolds for cultured meat applications. A physical cross-linking method based on water annealing was developed for the fabrication of porous glutenin sponges and fibrous aligned scaffolds. The ...
... The NASICON-type Na₄MnV(PO₄)₃ (NMVP) possesses potential as a cathode material in SIBs, and is known for its stable 3D Na⁺ superconductive framework, high voltage platform, and relatively low cost and toxicity. Nevertheless, the intrinsic poor electronic conductivity and Jahn–Teller effect from Mn³⁺ during cycling limit its further application. Herein, to address such issues, a well-designed 3D po ...
C. Tilden Hagan; Cameron Bloomquist; Samuel Warner; Nicole M. Knape; Isaiah Kim; Hayley Foley; Kyle T. Wagner; Sue Mecham; Joseph DeSimone; Andrew Z. Wang
... Surgery is an important treatment for cancer; however, local recurrence following macroscopically-complete resection is common and a significant cause of morbidity and mortality. Systemic chemotherapy is often employed as an adjuvant therapy to prevent recurrence of residual disease, but has limited efficacy due to poor penetration and dose-limiting off-target toxicities. Selective delivery of che ...
Ashley L. Farris; Dennis Lambrechts; Yuxiao Zhou; Nicholas Y. Zhang; Naboneeta Sarkar; Megan C. Moorer; Alexandra N. Rindone; Ethan L. Nyberg; Alexander Perdomo-Pantoja; S.J. Burris; Kendall Free; Timothy F. Witham; Ryan C. Riddle; Warren L. Grayson
... Low oxygen (O₂) diffusion into large tissue engineered scaffolds hinders the therapeutic efficacy of transplanted cells. To overcome this, we previously studied hollow, hyperbarically-loaded microtanks (μtanks) to serve as O₂ reservoirs. To adapt these for bone regeneration, we fabricated biodegradable μtanks from polyvinyl alcohol and poly (lactic-co-glycolic acid) and embedded them to form 3D-pr ...
... Series of thioether derivatives containing 4-methylumbelliferone fused oxazole moiety were designed and synthesised, their structures were fully characterized by ¹H NMR, ¹³C NMR and HR-ESI-MS as well. Moreover, the in vitro antifungal potency of the title compounds were preliminarily evaluated for their possible use as a fungicide. Meanwhile, ethyl thioethers 3aa and 3ba displayed remarkable inhib ...
colon; exposure assessment; food science; human health; intestinal mucosa; nutrition; oxidation; risk; temperature; toxicity; vitamin E
Abstract:
... Undoubtedly, significant advances were performed concerning 4-hydroxy-2-alkenals research on foods, and their formation by double oxidation of polyunsaturated fatty acids. But further studies are still needed, especially on their occurrence in foods enriched with n-3 and n-6 fatty acids, as well as in foods for infants and processed foods. Major factors concerning the formation of 4-hydroxy-2-alke ...
... Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol, has beneficial effects on human health. This study aimed to elucidate the detailed EGCG sulfation process to better understand its phase II metabolism, a process required to maximize its health benefits. Results show that kinetic activity of sulfation in the human liver and intestinal cytosol is 2-fold and 60- to 300-fold higher than ...
... 5-Demethylnobiletin (5DN) is a polymethoxyflavone (PMF) primarily found in citrus fruits. It has various health-promoting properties and hence has attracted significant attention from scholars worldwide. This review is the first to systematically summarize the recent research progress of 5DN, including its pharmacological activity, mechanism of action, pharmacokinetics, and toxicological effects. ...
... 5-Hydroxymethylfurfural (5-HMF) is a processing byproduct present in foods that are consumed daily by humans, and the diet is the principal route for human exposure to it. However, its adverse effects on gastric epithelial cells are not fully understood. Based on the half inhibitory concentration value, concentrations of HMF of 2, 4, 8, and 16 mM were selected for this study. After 5-HMF treatment ...
... In the current study, the role of chlorophyll precursor, 5-aminolevulinic acid (ALA) and its effect on growth attributes, photosynthetic pigments, indices of chlorophyll a fluorescence, nitrogen metabolism, and contents of protein and carbohydrate in seedlings of pigeon pea varities BAHAR and KB-17 under the enhanced ultraviolet (UV-B; 2.2 kJ m⁻²d⁻¹) radiations was investigated. Ultraviolet radiat ...
... Hydroxylated polybrominated diphenyl ethers (OH-BDEs) are major transformation products of PBDEs that readily bioaccumulate in the marine food web. Although 6-OH-BDE-47 is frequently and abundantly detected in cetaceans, its potential toxic effects are largely unknown. We explored the toxicological pathways and mechanisms of OH-BDEs by exposing pygmy killer whale skin fibroblast cell lines (PKW-LW ...
Zhenyu Tian; Melissa Gonzalez; Craig A. Rideout; Haoqi Nina Zhao; Ximin Hu; Jill Wetzel; Emma Mudrock; C. Andrew James; Jenifer K. McIntyre; Edward P. Kolodziej
Oncorhynchus kisutch; death; isotopes; juveniles; liquid chromatography; mortality; pollutants; stormwater; tandem mass spectrometry; technology; toxicity
Abstract:
... Stormwater exposure can cause acute mortality of coho salmon (Oncorhynchus kisutch), and 6PPD-quinone (6PPD-Q) was identified as the primary causal toxicant. Commercial standards of 6PPD-Q recently became available; their analysis highlighted a systematic high bias in prior reporting concerning 6PPD-Q. A 6PPD-Q commercial standard was used to re-confirm toxicity estimates in juvenile coho salmon a ...
... Several genomes of Nostocales ADA clade members from the US Pacific Northwest were recently sequenced. Biosynthetic genes for microcystin, cylindrospermopsin or anatoxin-a were present in 7 of the 15 Dolichospermum/Anabaena strains and none of the 5 Aphanizomenon flos-aquae (AFA) strains. Toxin analyses (ELISA and LC-MS/MS) were conducted to quantitate and identify microcystin (MC) and cylindrospe ...
... The multifunctional AAA+ ATPase p97 is an unfoldase/segregase involved in various cellular processes and present in all kingdoms of life. In mammals and yeast, p97 functions upstream of the proteasome. Interestingly, proteasome inhibitors targeting pathogenic microorganisms display efficacy in overcoming drug-resistant strains. Homologues of p97 have been found in disease-causing parasites and myc ...
... Methylglyoxal (MG) is a toxic by‐product of the glycolysis pathway in most living organisms and was previously shown to inhibit seed germination. MG is detoxified by glyoxalase I and II family proteins in plants. MG is abundantly produced during early embryogenesis in Arabidopsis seeds. However, the mechanism that alleviates the toxic effect of MG in maturing seeds is poorly understood. In this st ...
... Skin is constantly exposed to environmental insults, including toxic chemicals and oxidative stress. These insults often provoke perturbation of epidermal homeostasis and lead to characteristic skin diseases. AHR (aryl hydrocarbon receptor) and NRF2 (nuclear factor erythroid 2-related factor 2) are transcription factors that induce a battery of cytoprotective genes encoding detoxication and antiox ...
anti-infective agents; antibacterial properties; biocompatibility; drug resistance; fluorescence; human health; hydrogen peroxide; lighting; montmorillonite; photochemotherapy; photosensitizing agents; precision medicine; singlet oxygen; toxicity; white light
Abstract:
... With the emergence and global spread of bacterial resistance, pathogenic bacterial infections have become a serious threat to human health. Thus, therapeutic strategies with highly antibacterial efficacy and a low tendency to induce drug resistance are strongly desired to combat bacterial infections. Here, an ultra-efficient photodynamic/chemodynamic theranostics platform is developed by intercala ...
... Silicon (Si) has the potential to ameliorate the toxic effects of cadmium (Cd) on rice growth and mitigate Cd-uptake by rice under Cd-contaminated soil. However, it is not completely clear whether there are differences in the impacts of different Si management on the chemical behavior of Cd in soil-rice system under Cd-contaminated paddy field. Here, pot trials were conducted to explore the effect ...
... Environmentally benign CeO₂–WO₃/TiO₂ catalysts are promising alternatives to commercial toxic V₂O₅–WO₃/TiO₂ for controlling NOₓ emission via selective catalytic reduction (SCR), but the insufficient catalytic activity of CeO₂–WO₃/TiO₂ catalysts is one of the obstacles in their applications because of a lack of an in-depth understanding of the CeO₂–WO₃ interactions. Herein, we design a Ce₁–W₁/TiO₂ ...
... Several reports have given credence to the acceptance of Abelmoschus esculentus (L) Moench (okra) leaf or “Ilasa soup” in Igbo-Ora, Oyo State, Nigeria, which has a record as the world's highest twinning rate influences their multiple births. Okra fruit is highly consumed in Nigeria and had been proposed to be responsible for modulating hormones that are responsible for sterility in males as a resu ...
... The antiozonant N-phenyl-N’-(1,3-dimethylbutyl)-p-phenylenediamine (6-PPD) is added to tires to increase their lifetime and is emitted with tire and road wear particles into the environment. Recently, one of its transformation products (TPs), 6-PPD quinone (6-PPDQ), has gained attention due to its toxicity towards coho salmon. In this study, the abiotic oxidative transformation of 6-PPD is investi ...
... Cadmium (Cd) is a highly toxic heavy metal. Abscisic acid (ABA) is a regulator that has various functions in plants. To further explore the mechanism by which ABA alleviates Cd damage in plants, ABA and fluridone, which inhibits ABA biosynthesis, were separately sprayed on the leaves of Malus hupehensis Rehd. (M. hupehensis) seedlings treated with Cd. The root Cd²⁺ flux in vivo, the accumulation a ...
... There are no specific drugs for the treatment of Japanese Encephalitis. Thus, new chemical entities or exploration of existing molecules is required. We have tested the antiviral potential of abscisic acid and aloe-emodin against protease of the Japanese encephalitis virus (JEV) using the computational and target-based assay. Maestro Schrödinger glide suite 2019 was used for molecular docking and ...
... Microplastics (MPs; <5 mm) in the biosphere draws public concern about their potential health impacts. Humans are potentially exposed to MPs via ingestion, inhalation, and dermal contact. Ingestion and inhalation are the two major exposure pathways. An adult may consume approximately 5.1 × 10³ items from table salts and up to 4.1 × 10⁴ items via drinking water annually. Meanwhile, MP inhalation in ...
... Listeria monocytogenes is a ubiquitous Gram-positive foodborne pathogen that is responsible for listeriosis in both humans and several animal species. The bacterium secretes a pore-forming cholesterol-dependent cytolysin, listeriolysin O (LLO), a major virulence factor involved in the activation of cellular processes. The ability of LLO to lyse erythrocytes is a measure of LLO activity. We used he ...
... Acaricidal activities and acetylcholinesterase (AChE) inhibitory activities were evaluated of active constituents of the essential oil extracted from Alpinia galanga rhizomes cultivated from India and their derivatives against Haemaphysalis longicornis nymphs. In addition, the effect was investigated of active components of A. galanga oil on egg laying of adult females of H. longicornis and egg ha ...
... Two-spotted spider mite (Tetranychus urticae Koch) has been considered among the most important phytophagous pest both in field and greenhouse crops around tropical areas of the globe. Although synthetic pesticides have remained as the main method to control mite populations, alternatives strategies as biopesticides based on secondary metabolites derived from plants should be considered. Ascending ...
activation energy; alcohols; dry environmental conditions; green chemistry; toxicity
Abstract:
... A key to commercializing perovskite solar cells (PSCs) is to use less toxic solvents such as water, alcohol, and other nontoxic compounds when printing them. Improving the perovskite crystal growth rate to reduce defects produced by the Ostwald ripening effect is a critical challenge in fabricating high-quality perovskite films from aqueous inks. In this study, we reported an accelerated crystal g ...
aquatic organisms; artificial intelligence; chemical structure; data collection; databases; ecotoxicology; lethal concentration 50; neural networks; toxicity
Abstract:
... Species Sensitivity Distribution (SSD) is a key metric for understanding the potential ecotoxicological impacts of chemicals. However, SSDs have been developed to estimate for only handful of chemicals due to the scarcity of experimental toxicity data. Here we present a novel approach to expand the chemical coverage of SSDs using Artificial Neural Network (ANN). We collected over 2000 experimental ...
Fourier transform infrared spectroscopy; biodegradation; decolorization; density functional theory; electron transfer; liquid chromatography; methyl orange; mineralization; photocatalysis; semiconductors; toxicity; voltammetry
Abstract:
... In this study, a n-type semiconductor perylene diimide (PDI) was coupled with biodegradation to accelerate the biotic decolorization and mineralization of methyl orange (MO) under light condition. The decolorization rates (k₁) of MO in pure and mixed cultures with PDI were promoted by 1.35 and 1.79 folds, respectively, comparing to the cultures without PDI. The total mineralization efficiency of 4 ...
... Antimicrobial-resistant is a major challenge in to treat infected wounds, and new formulations should be produced. Citral (Citl), chitosan (Chsn), and zinc oxide (ZnO) nanoparticles may accelerate the wound healing process in terms of their antibacterial properties. This new study aimed to investigate the effects of ointments produced from ZnO/Chsn/Citl nanoparticles (NPs) to treat the infected wo ...
... Several studies have demonstrated that the biodegradation of resorcinol as a major pollutant in domestic coal gas wastewater can vary greatly with respect to its physicochemical properties and the structure of the bacterial flora induced during acclimation. The primary objective of this study is to investigate the degradation of resorcinol by aerobic activated sludge at different stages of domesti ...
... Seaweeds could play a significant role in alleviating coastal chemical pollution through accumulation and degradation. In the present study, the accumulation and degradation patterns of triphenyltin chloride (TPTCL) and tributyltin chloride (TBTCL) in young and matured sporophytes of cultivated Undaria pinnatifida were examined under three concentrations of 0.5, 1, and 5 μg L⁻¹. The growth of youn ...
... Three ²¹⁰Pb-dated sediment cores were used to evaluate the contamination degree and flux ratios of potentially toxic elements (PTEs; As, Cd, Cr, Cu, Ni, Pb, V, and Zn) in seagrass meadows from the northern margin of Términos Lagoon (TL), southern Gulf of Mexico. The sediments displayed minor Cd, Ni, V, and Zn enrichments but moderate to strong enrichment by As. Results from a chemometric analysis ...
... Cropland contamination by toxic trace metal (loid)s (TTMs) has attracted increasing attention due to the serious consequential threat to crop quality and human health. Mitigation of plant TTM stress by silica amendment has been proposed recently. However, the relationship between the siliceous structure of phytoliths and TTMs in plants, and the environmental implications of phytolith-occluded trac ...
Monte Carlo method; acceptable daily intake; average daily intake; breast feeding; breast milk; dibenzofuran; dietary exposure; pollution; polychlorinated biphenyls; polychlorinated dibenzodioxins; probability distribution; risk; seafoods; toxicity; China
Abstract:
... Breast milk samples were collected from 51 mothers in a seaside city Dalian, where the residents usually have higher dietary exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) due to the larger consumption of seafood. The lipid-basis concentrations of ∑Cl₂–₈DD/Fs, ∑Cl₂–₁₀Bs, and total toxicity equivalent (WHO-TEQ) were measured to be in t ...
... Vegetables are widely cultivated in high rainfall and mountainous regions in Sri Lanka with poor soil conservation practices. Accumulation of essential mineral and toxic trace elements in the soils and widely cultivated vegetables of this region are poorly understood. One hundred soil and vegetable (i.e. cabbage, carrot and potato) samples were collected at the time of harvest and analysed for ele ...
... Mangroves are highly dynamic ecosystems that offer important services such as maintaining biodiversity, filtering pollutants, and providing habitats for fishes. We investigated the uptake and accumulation of nutrients and potentially toxic elements in mangrove plants and fish to better understand the role of mangrove restoration in maintaining mangrove biota quality. In mangrove plants, the averag ...
... Microplastics have become a worldwide pollutant, widely discovered in soil, air and aquatic environment. Microplastics have been found in habitats where crayfish (Procambarus clarkii) cultivated, but the impact of microplastics on crayfish remains unclear. In this study, after 21-day dietary exposure, polyethylene (PE) particles were found to accumulate in intestine, hepatopancreas, gills and hemo ...
... The environmental pollution from microplastics has caused concern from the whole society due to its harm to organisms. However, the effect of microplastics on liver damage and fibrosis remains unclear in the case of long-term accumulation. The present study demonstrated that the 0.1 μm microplastic could enter hepatocytes from circulation and result liver damage even at a low concentration. Microp ...
... Though gold mines provide significant economic benefits to local governments, mining causes soil pollution by potentially toxic trace elements (PTEs) in mining areas, especially in the Qinghai-Tibet Plateau. Screening of native plant species from mining areas is now an effective, inexpensive, and eco-friendly method for the remediation of PTEs in situ. In the present study, we conducted experiment ...
... One of the best studied global “hot spots” for ecological mercury (Hg) contamination is south Florida (USA), where elevated Hg concentrations in environmental media and regional wildlife were first described over thirty years ago. While Hg contamination has lessened in this region, it is still critical to monitor Hg uptake and potential risks in south Florida wildlife, especially in marine-associa ...
Natasha Natasha; Muhammad Shahid; Behzad Murtaza; Irshad Bibi; Sana Khalid; Abdullah A. Al-Kahtani; Rabia Naz; Esmat F. Ali; Nabeel Khan Niazi; Jörg Rinklebe; Sabry M. Shaheen
... There are scarce data about the accumulation pattern and risk assessment of potentially toxic elements (PTEs) in soil and associated potential ecological risks, especially in less-developed countries. This study aims to assess the pollution levels and potential ecological risks of PTEs (As, Cr, Cd, Cu, Ni, Mn, Pb and Zn) in wastewater-irrigated arable soils and different edible-grown plants in sel ...
... Dibutyl phthalate (DBP) is one of the most commonly used and toxic phthalate esters and has a variety of harmful effects on aquatic animals. However, there is still a lack of knowledge on the accumulation, detoxification, and toxicity of DBP in aquatic animals. In this study, we chose the swimming crab Portunus trituberculatus, an ecologically and economically important species, as the model and i ...
... The study of the fate of organophosphate esters (OPEs) in the interior environment is vital because of the growing use of OPEs. Organic films on glass are both sink and sources of indoor pollutants. Indoor window films have been employed as passive air samplers to collect OPEs in the indoor air. Nevertheless, little is known about the development and equilibrium condition of OPEs on indoor window ...
adsorption; electron transfer; remediation; toxicity; wastewater treatment
Abstract:
... Characteristic emerging pollutants at low concentration have raised much attention for causing a bottleneck in water remediation, especially in complex water matrices where high concentration of interferents coexist. In the future, tailored treatment methods are therefore of increasing significance for accurate removal of target pollutants in different water matrices. This critical review focuses ...
... A bionanocomposite comprising of magnetic chitosan doped with algae isolated from native habitat was fabricated and utilized as an efficient adsorbent for the removal of hazardous azo dyes, namely, Direct Red 31 (DR31) and Direct Red 28 (DR28). The algal doped magnetic chitosan (Alg@mCS) was comprehensively characterized by Scanning Electron Microscopy (SEM), Energy Dispersive X-Ray Analysis (EDAX ...
... The principal desirable characteristics of the yeasts used in order to maintain the yield and the efficiency high during the process of ethanol production are mainly thermotolerance, Killer activity and high resistance to inhibitor compounds like acetic acid. Yeast represents the most important factor to achieve an efficient conversion process of the different raw materials used to produce ethanol ...
acetic acid; adsorbents; atomic absorption spectrometry; chemical species; ionic strength; pH; solid phase extraction; toxicity; toxicology; water pollution; zinc oxide
Abstract:
... Water pollution due to toxic metals may pose a significant effect on the environment and the biota indicating the necessity of careful management of their concentration in the system. On the other hand, a simplified and useable sample preparation technique is required for their trace analysis. In this report, a simple solid-phase extraction procedure was developed for fast extraction and preconcen ...
... The biological effect of acetone extracts from three selected plants, Lantana camara, Rhazya astricta, and Citrullus colocynthis, on the egg hatch rate, larvicidal activity, and larval development of Culex pipiens L. was investigated. The egg hatch rate of Cx. pipiens was significantly reduced (P<0.01) when the extracts of L. camara were used. Moreover, the used extracts significantly exhibited a ...