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- Falcón-Pérez, Juan Manuel, et al. Show all 5 Authors
- FEBS letters 2012 v.586 no.1 pp. 47-54
- culture media; secretion; toxicity
- ... Increasing amounts of tau protein were expressed in non-neuronal cells. When intracellular amounts reached a threshold level, tau protein was released to the extracellular culture medium in association with membrane vesicles. Hence, we propose that tau might be secreted through membrane vesicles as a cellular mechanism to eliminate the excess of tau protein, thereby avoiding its toxicity. ...
- Davies-McConchie, J. Falcon, et al. Show all 2 Author
- Industrial & Engineering Chemistry Research 2012 v.51 no.28 pp. 9634-9641
- arsenates; arsenic; arsenites; carcinogens; chemistry; copper; drinking water; filters; filtration; groundwater; heavy metals; lead; toxicity; wool; zinc
- ... Arsenic and heavy metals in drinking water are of particular concern. Of them arsenic is the most potent toxin as well as it is a carcinogen. Arsenic exists in groundwater as uncharged arsenite or anionic arsenate depending on the reducing or oxidizing environment, and the former is more toxic and more difficult to remove than the latter. In this work, varous types of filters made from Bauxsol imm ...
- Falcon, Carlos, et al. Show all 6 Authors
- Analytical chemistry 2018 v.90 no.4 pp. 2772-2779
- Alzheimer disease; amyloid; brain; cell culture; humans; oxidation; oxidative stress; principal component analysis; spectroscopy; toxicity
- ... Amyloid plaques made of aggregated Aβ amyloid peptide are a pathological hallmark in brains affected by Alzheimer’s disease (AD). Moreover, the amyloid peptide may play a major role in the onset and development of the disease in association to other factors such as oxidative stress. Although the molecular nature of the amyloid toxic species is still unknown, there is experimental evidence pointing ...