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1. Epigenetic silencing of ALX4 regulates microcystin-LR induced hepatocellular carcinoma through the P53 pathway

Author:
Cao, Jia,   et al.   ; Zhao, Ji; Chen, Hong-qiang; Yang, Hui-fang; Li, Yan; Chen, Dong-jiao; Huang, Yu-jing; He, Li-xiong; Zheng, Chuan-fen; Wang, Ling-qiao; Wang, Jia; Zhang, Na; Liu, Jin-yi; Shu, Wei-qun; Liu, Wen-bin;     Show all 15 Authors
Source:
The Science of the total environment 2019 v.683 pp. 317-330
ISSN:
0048-9697
Subject:
DNA methylation; Western blotting; animal models; antineoplastic activity; apoptosis; bisulfites; blood serum; cell proliferation; demethylation; epigenetics; gene expression regulation; hepatoma; metastasis; microcystin-LR; patients; promoter regions; reverse transcriptase polymerase chain reaction
Abstract:
... Recent studies have shown that microcystin-LR (MC-LR) is one of the principal factors that cause liver cancer. Previously we have found that Aristaless-like Homeobox 4 (ALX4) was differentially expressed in MC-LR-induced malignant transformed L02 cells. However, the expression regulation, role and molecular mechanism of ALX4 during the process of liver cancer induced by MC-LR are still unclear. Th ...
DOI:
10.1016/j.scitotenv.2019.05.144

2. Epigenetic inactivation of LHX6 mediated microcystin-LR induced hepatocarcinogenesis via the Wnt/β-catenin and P53 signaling pathways

Author:
Cao, Jia,   et al.   ; Chen, Hong-qiang; Zhao, Ji; Li, Yan; Huang, Yu-jing; Chen, Dong-jiao; He, Li-xiong; Wang, Ling-qiao; Zheng, Chuan-fen; Wang, Jia; Shu, Wei-qun; Liu, Jin-yi; Liu, Wen-bin;     Show all 13 Authors
Source:
Environmental pollution 2019 v.252 pp. 216-226
ISSN:
0269-7491
Subject:
DNA methylation; apoptosis; biomarkers; body weight; carcinogenicity; epidemiological studies; epigenetics; gene overexpression; hepatoma; homeotic genes; humans; liver; microcystin-LR; models; phenotype; rats; signal transduction
Abstract:
... Microcystins (MCs) have been shown to be carcinogenic by animal and cellular experiments and found to be associated with the development of human hepatocellular carcinoma (HCC) through epidemiological studies. However, the molecular mechanism of microcystin-LR (MC-LR) induced HCC is still unclear. This study is determined to clarify the role and mechanism of LHX6 in MC-LR-induced hepatocarcinogene ...
DOI:
10.1016/j.envpol.2019.05.049

3. Species identification and molecular characterization of Cronobacter spp. isolated from food imported over nine years into Beijing, China

Author:
Cao, Jia-Yue,   et al.   ; Wang, Qi; Forsythe, Stephen James; Zhao, Xiao-Juan; Wang, Zi-Wei; Li, Dan; Ma, Dan; Zeng, Jing;     Show all 8 Authors
Source:
Food microbiology 2019 v.82 pp. 11-19
ISSN:
0740-0020
Subject:
Cronobacter sakazakii; alleles; bacteremia; databases; desorption; enterocolitis; matrix-assisted laser desorption-ionization mass spectrometry; meningitis; multilocus sequence typing; neonates; pathovars; serotypes; species identification; China
Abstract:
... Cronobacter spp. are associated with serious infections in neonates with the clinical presentations of necrotizing enterocolitis, bacteraemia and meningitis. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was used to identify 203 Cronobacter isolates from imported food during 2006–2015 with an optimized in-house database. The isolates were predominantly ...
DOI:
10.1016/j.fm.2019.01.011

4. A huge novel polyoxometalate-based cluster Fe₁₀P₄W₃₂ exhibiting prominent electrocatalytic activity for the oxygen evolution reaction and third-order NLO properties

Author:
Cao, Jia-Peng,   et al.   ; JiangW. Jiang and X.-M. Liu contributed equally., Wei; Liu, Xiao-Mei; Liu, Jian; Shi, Jie; Luo, Xi-Ming; You, Wan-Sheng; Xu, Yan;     Show all 8 Authors
Source:
Chemical communications 2019 v.55 no.63 pp. 9299-9302
ISSN:
1364-548X
Subject:
catalytic activity; chemical reactions; electrochemistry; ions; iron; ligands; magnetic properties; oxygen production; sodium
Abstract:
... Two novel POM-based huge clusters modified by conjugated organic ligands (DAPSC), {Fe₁₀P₄W₃₂} and {Fe₈MoW₁₈}, have been successfully isolated. Compound 1 consists of a novel huge inorganic building block {Fe₁₀P₄W₃₂} and four organic groups DAPSC linked by ten iron ions and four sodium ions. The DAPSC ligands enhance the electric delocalization effects of polyoxoanions, leading to strengthening of ...
DOI:
10.1039/c9cc03937f

5. Two zinc(ii) coordination polymers based on flexible co-ligands featuring assembly imparted sensing abilities for Cr₂O₇²⁻ and o-NP

Author:
Cao, Jia,   et al.   ; Zhang, Meili; Zheng, Yanjin; Liu, Min; Ren, Yixia; Wang, Zhixiang; Wang, Jijiang;     Show all 7 Authors
Source:
RSC advances 2019 v.9 no.37 pp. 21086-21094
ISSN:
2046-2069
Subject:
aqueous solutions; chromates; coordination polymers; detection limit; emissions; fluorescence; imidazole; ligands; zinc
Abstract:
... Two new Zn(ii) coordination complexes, formulated as [Zn(opda)(pbib)] (1) and [Zn(ppda)(pbib)(H₂O)] (2), (H₂opda = 1,2-phenylenediacetic acid, H₂ppda = 1,4-phenylene-diacetic acid, pbib = 1,4-bis(1-imidazoly)benzene), have been synthesized. The opda ligands extend a 1D chain containing (Zn-pbib) polymer chains into a 2D layer in 1. In 2, the ppda ligands link Zn(ii) atoms to form a 2D network, the ...
DOI:
10.1039/c9ra03822a

6. Characterization of interactions between a metabolic uncoupler O-chlorophenol and extracellular polymeric substances of activated sludge

Author:
Cao, Jia-Shun,   et al.   ; Fang, Fang; Xu, Run-Ze; Wang, Su-Na; Zhang, Lu-Lu; Huang, Yan-Qiu; Luo, Jing-Yang; Feng, Qian;     Show all 8 Authors
Source:
Environmental pollution 2019 v.247 pp. 1020-1027
ISSN:
0269-7491
Subject:
Fourier transform infrared spectroscopy; X-ray photoelectron spectroscopy; activated sludge; fluorescence; moieties; nuclear magnetic resonance spectroscopy; tyrosine; wastewater treatment
Abstract:
... Metabolic uncouplers are widely used for the in-situ reduction of excess sludge from activated sludge systems. However, the interaction mechanism between the metabolic uncouplers and extracellular polymeric substances (EPS) of activated sludge is unknown yet. In this study, the interactions between a typical metabolic uncoupler, o-chlorophenol (oCP), and the EPS extracted from activated sludge wer ...
DOI:
10.1016/j.envpol.2019.02.005

7. SpyTag/SpyCatcher molecular cyclization confers protein stability and resilience to aggregation

Author:
Cao, Jia-Wen,   et al.   ; Sun, Xiao-Bao; Wang, Jia-Kun; Lin, Hai-Zhen; Gao, De-Ying; Qian, Guo-Ying; Park, Yong-Doo; Chen, Zhong-Fa; Wang, Qian;     Show all 9 Authors
Source:
New biotechnology 2019 v.49 pp. 28-36
ISSN:
1871-6784
Subject:
circular dichroism spectroscopy; denaturation; directed evolution; engineering; feed additives; industrial applications; lignocellulose; oligosaccharides; peptides; site-directed mutagenesis; xylanases
Abstract:
... The capacities for thermal and inhibitor tolerance are critical for industrial enzymes and loss of activity is a major challenge in deploying natural enzymes for commercial applications. Protein engineering approaches, such as site-directed mutagenesis and directed evolution, have been devoted to modifying natural enzymes. Recently, a post-translation protein engineering strategy, the SpyTag/SpyCa ...
DOI:
10.1016/j.nbt.2018.12.003

8. Construction of stabilized (R)-selective amine transaminase from Aspergillus terreus by consensus mutagenesis

Author:
Cao, Jia-Ren,   et al.   ; Xie, Dong-Fang; Yang, Jun-Xing; Lv, Chang-Jiang; Mei, Jia-Qi; Wang, Hong-Peng; Hu, Sheng; Zhao, Wei-Rui; Tu, Jun-Liang; Huang, Jun; Mei, Le-He;     Show all 11 Authors
Source:
Journal of biotechnology 2019 v.293 pp. 8-16
ISSN:
0168-1656
Subject:
Aspergillus terreus; Gibbs free energy; amines; amino acids; biocatalysts; consensus sequence; disulfide bonds; half life; mutants; site-directed mutagenesis; thermal stability; transaminases
Abstract:
... Amine transaminases are a class of efficient and industrially-desired biocatalysts for the production of chiral amines. In this study, stabilized variants of the (R)-selective amine transaminase from Aspergillus terreus (AT-ATA) were constructed by consensus mutagenesis. Using Consensus Finder (http://cbs-kazlab.oit.umn.edu/), six positions with the most prevalent amino acid (over 60% threshold) a ...
DOI:
10.1016/j.jbiotec.2019.01.007

9. Metabolomic and transcriptomic analyses reveal the effects of ultraviolet radiation deprivation on Isochrysis galbana at high temperature

Author:
Cao, Jia-Yi,   et al.   ; Kong, Zhou-Yan; Ye, Meng-Wei; Zhang, Yu-Fan; Xu, Ji-Lin; Zhou, Cheng-Xu; Liao, Kai; Yan, Xiao-Jun;     Show all 8 Authors
Source:
Algal research 2019 v.38 pp. 101424
ISSN:
2211-9264
Subject:
Isochrysis galbana; biomass; carboxylic acids; carboxylic ester hydrolases; diacylglycerols; financial economics; genes; industry; mariculture; metabolomics; microalgae; oxygen production; photochemistry; photosystem II; solar radiation; summer; temperature; transcriptomics; transferases; triacylglycerols; tricarboxylic acid cycle; ultraviolet radiation
Abstract:
... The microalga Isochrysis galbana exhibits a seasonal fluctuation of biomass referred to as ‘decline’ during summer, leading to a great economic loss in the mariculture industry. In the present study, we aimed to explore the role of ultraviolet radiation (UVR) in I. galbana decline at high temperature by integrated analysis of metabolomic and transcriptomic data. The positive effects of UVR depriva ...
DOI:
10.1016/j.algal.2019.101424

10. Isolation, Structure Elucidation, and Total Synthesis of Myrtuspirone A from Myrtus communis

Author:
Cao, Jia-Qing,   et al.   ; Cheng, Min-Jing; Yang, Xin-Yi; Liu, Chao; Zhong, Li-Ping; Wang, Ying; You, Xue-Fu; Li, Chuang-Chuang; Wang, Lei; Ye, Wen-Cai;     Show all 10 Authors
Source:
Organic letters 2019 v.21 no.6 pp. 1583-1587
ISSN:
1523-7052
Subject:
Gram-positive bacteria; Myrtus communis; X-ray diffraction; antibacterial properties; chemical reactions; enantiomers; leaves; multiple drug resistance; organic compounds
Abstract:
... A pair of enantiomeric triketone–phloroglucinol hybrids, (+)- and (−)-myrtuspirone A (1), featuring an unprecedented 3-isopropyl-3H-spiro[benzofuran-2,1′-cyclohexane] backbone, were isolated from the leaves of Myrtus communis. The absolute configuration of each enantiomer of 1 was determined by X-ray diffraction and chemical calculations. Furthermore, the gram-scale total syntheses of (±)-1 and (− ...
DOI:
10.1021/acs.orglett.9b00108

11. Organocatalytic decarboxylative alkylation of N-hydroxy-phthalimide esters enabled by pyridine-boryl radicals

Author:
Cao, Jia,   et al.   ; GaoThese authors contributed equally to this work., Liuzhou; Wang, Guoqiang; Yuan, Dandan; Xu, Cheng; Guo, Xuewen; Li, Shuhua;     Show all 7 Authors
Source:
Chemical communications 2018 v.54 no.82 pp. 11534-11537
ISSN:
1364-548X
Subject:
alkenes; alkylation; carboxylic acids; catalytic activity; decarboxylation; density functional theory; electron transfer; esters; free radicals
Abstract:
... The decarboxylative alkylation of N-hydroxyphthalimide (NHPI) based reactive esters with olefins has been achieved via an organocatalytic strategy. Control experiments and density functional theory calculations suggest that these reactions involve a boryl-radical mediated decarboxylation pathway, which is different from the single electron transfer involved in decarboxylative alkylation reactions ...
DOI:
10.1039/c8cc06152a

12. Evaluation of Groundwater Quality in the Vicinity of Khurrianwala Industrial Zone, Pakistan

Author:
Shun, Cao Jia,   et al.   ; Aleem, Muhammad; Li, Chao; Aslam, Arslan Muhammad; Yang, Wu; Nawaz, Muhammad Imran; Ahmed, Wasif Saeed; Buttar, Noman Ali;     Show all 8 Authors
Source:
Water 2018 v.10 no.10
ISSN:
2073-4441
Subject:
World Health Organization; anions; anthropogenic activities; arsenic; bicarbonates; calcium; calcium carbonate; cations; chlorides; developing countries; dissolved oxygen; drinking; drinking water; electrical conductivity; geographic information systems; groundwater; iron; irrigation; irrigation water; magnesium; oxygen; pH; phosphates; pollutants; potassium; sodium; sodium adsorption ratio; sodium carbonate; soil; sulfates; total dissolved solids; total phosphorus; water hardness; Pakistan
Abstract:
... The industrial augmentation and unguided anthropogenic activities contaminate water sources in most parts of the world especially in developing countries like Pakistan. High concentration of pollutants in groundwater affects human, soil, and crop health badly. The present study was conducted to investigate groundwater quality for drinking and irrigation purposes in an industrial zone of Pakistan. ...
DOI:
10.3390/w10101321

13. The zinc-finger transcription factor BcMF20 and its orthologs in Cruciferae which are required for pollen development

Author:
Cao, Jia-Shu,   et al.   ; Han, Ying-Yan; Zhou, Hui-Yan; Xu, Li-Ai; Liu, Xue-Ying; Fan, Shuang-Xi;     Show all 6 Authors
Source:
Biochemical and biophysical research communications 2018 v.503 no.2 pp. 998-1003
ISSN:
0006-291X
Subject:
Arabidopsis thaliana; Brassica rapa subsp. chinensis; Brassica rapa subsp. oleifera; Chinese cabbage; abnormal development; antisense RNA; buds; fruit set; genes; germination; male fertility; microspores; mutants; phylogeny; pollen; scanning electron microscopy; transcription factors; transgenesis; transmission electron microscopy
Abstract:
... Brassica campestris Male Fertility 20 (BcMF20) is a typical zinc-finger transcription factor that was previously isolated from flower buds of Chinese cabbage (Brassica campestris ssp. chinensis). By applying expression pattern analysis, it can be known that BcMF20 was specifically and strongly expressed in tapetum and pollen, beginning from the uninucleate stage, and was maintained during the matu ...
DOI:
10.1016/j.bbrc.2018.06.108

14. Anxiolytic potency of iridoid fraction extracted from Valeriana jatamansi Jones and its mechanism: a preliminary study

Author:
Cao, Jia-Hong,   et al.   ; Zhang, Xue-Mei; Zhu, Jia-Li; Sun, Yong; Dai, Yao-Lan; Chen, Xiu; Yang, Ruo-Cong; Chen, Chang; Ma, Chao-Ying; Zhang, Tian-E; Chen, Yun-Hui; Yan, Zhi-Yong;     Show all 12 Authors
Source:
Natural product research 2018 v.32 no.17 pp. 2071-2075
ISSN:
1478-6427
Subject:
Valeriana jatamansi; anxiety; drinking; elevated plus-maze test; enzyme-linked immunosorbent assay; gamma-aminobutyric acid; high performance liquid chromatography; rhizomes; spectroscopy; thin layer chromatography; tranquilizers
Abstract:
... Valeriana jatamansi Jones (V. jatamansi) has been widely used for treating anxiety and its mechanism involves many aspects including GABA level. This study aimed to evaluate the anxiolytic potency of an iridoid fraction extracted from the radix and rhizomes of V. jatamansi. The iridoid fraction was extracted by using D101 resin; its major components were analysed preliminarily by thin layer chroma ...
DOI:
10.1080/14786419.2017.1360881

15. Exploring the Performance Improvement of Magnetocaloric Effect Based Gd-Exclusive Cluster Gd60

Author:
Cao, Jia-Peng,   et al.   ; Luo, Xi-Ming; Hu, Zhao-Bo; Lin, Qing-fang; Cheng, Weiwei; Cui, Chen-Hui; Mei, Hua; Song, You; Xu, Yan;     Show all 9 Authors
Source:
Journal of the American Chemical Society 2018 v.140 no.36 pp. 11219-11222
ISSN:
1520-5126
Subject:
acetates; acetonitrile; carbonates; entropy; gadolinium; hydrolysis; ligands; magnetism; nitrates
Abstract:
... Despite wide potential applications of Gd-clusters in magnetocaloric effect (MCE) owing to f⁷ electron configuration of Gd(III), the structural improvement in order to enhance MCE remains difficult. A new approach of the situ hydrolysis of acetonitrile is reported, and the slow release of small ligand CH₃COO– is realized in the design and synthesis of high-nuclearity lanthanide clusters. A large l ...
DOI:
10.1021/jacs.8b07841

16. Leaf stage‐associated resistance is correlated with phytohormones in a pathosystem‐dependent manner

Author:
Cao, Jia‐Yi,   et al.   ; Xu, You‐Ping; Lv, Lin‐Hui; Xu, Ya‐Jing; Yang, Juan; Cai, Xin‐Zhong;     Show all 6 Authors
Source:
Journal of integrative plant biology 2018 v.60 no.8 pp. 703-722
ISSN:
1672-9072
Subject:
Arabidopsis thaliana; Nicotiana tabacum; Pseudomonas syringae pv. tabaci; Sclerotinia sclerotiorum; abscisic acid; biosynthesis; calcium signaling; disease resistance; ethylene; gene expression regulation; genes; hosts; immunity; jasmonic acid; leaves; microarray technology; mutants; pathogens; salicylic acid; tomatoes
Abstract:
... It has been reported in several pathosystems that disease resistance can vary in leaves at different stages. However, how general this leaf stage‐associated resistance is, and the molecular mechanism(s) underlying it, remain largely unknown. Here, we investigated the effect of leaf stage on basal resistance, effector‐triggered immunity (ETI) and nonhost resistance, using eight pathosystems involvi ...
DOI:
10.1111/jipb.12661

17. Proton conductivity resulting from different triazole-based ligands in two new bifunctional decavanadates

Author:
Cao, Jia-Peng,   et al.   ; Shen, Feng-Cui; Luo, Xi-Ming; Cui, Chen-Hui; Lan, Ya-Qian; Xu, Yan;     Show all 6 Authors
Source:
RSC advances 2018 v.8 no.33 pp. 18560-18566
ISSN:
2046-2069
Subject:
amines; aqueous solutions; evaporation; imidazoles; ligands; porous media; triazoles
Abstract:
... Triazole, similarly to imidazole, makes a prominent contribution to the proton conductivity of porous materials. To investigate the effects of triazole-based ligands in polyoxovanadates (POVs) on proton conduction, we designed and synthesized two decavanadate-based POVs, [Zn₃(C₂H₄N₄)₆(H₂O)₆](V₁₀O₂₈)·14H₂O (1) and [Zn₃(C₂H₃N₃)₈(H₂O)₄](V₁₀O₂₈)·8H₂O (2) constructed from the ligands 3-amino-1,2,4-tria ...
DOI:
10.1039/c8ra02694g

18. A novel 33-bp insertion in the promoter of TaMFT-3A is associated with pre-harvest sprouting resistance in common wheat

Author:
Cao, Jia-Jia,   et al.   ; Jiang, Hao; Zhao, Liang-Xia; Chen, Xue-Jian; Wu, Zeng-Yun; Liu, Kai; Zhang, Can; Wei, Wen-Xin; Xie, Hong-Yong; Li, Li; Gan, Yi-Gang; Lu, Jie; Chang, Cheng; Zhang, Hai-Ping; Xia, Xian-Chun; Xiao, Shi-He; Ma, Chuan-Xi;     Show all 17 Authors
Source:
Molecular breeding 2018 v.38 no.5 pp. 69
ISSN:
1380-3743
Subject:
Triticum aestivum; abscisic acid; acid treatment; alleles; breeding; chromosome mapping; gibberellic acid; haplotypes; inbred lines; loci; phenotypic variation; preharvest sprouting resistance; promoter regions; quantitative trait loci; single nucleotide polymorphism; sprouting; vivipary (plants); wheat
Abstract:
... TaMFT-3A on wheat chromosome 3AS, encoding a phosphatidyl ethanolamine-binding protein, was previously determined to be a candidate gene underlying the major quantitative trait locus (QTL) for pre-harvest sprouting (PHS) resistance. Three single nucleotide polymorphisms (SNPs) (−222, +646, and +666) and one insertion/deletion (InDel) variation at TaMFT-3A locus are associated with PHS resistance. ...
DOI:
10.1007/s11032-018-0830-1

19. TERT regulates telomere-related senescence and apoptosis through DNA damage response in male germ cells exposed to BPDE in vitro and to B[a]P in vivo

Author:
Cao, Jia,   et al.   ; Ling, Xi; Yang, Wang; Zou, Peng; Zhang, Guowei; Wang, Zhi; Zhang, Xi; Chen, Hongqiang; Peng, Kaige; Han, Fei; Liu, Jinyi; Ao, Lin;     Show all 12 Authors
Source:
Environmental pollution 2018 v.235 pp. 836-849
ISSN:
0269-7491
Subject:
DNA damage; adverse effects; apoptosis; benzo(a)pyrene; cell viability; dose response; environmental factors; enzyme activity; germ cells; histology; male fertility; males; metabolites; mice; models; pollutants; polycyclic aromatic hydrocarbons; proteins; rats; telomerase; telomeres; testes
Abstract:
... Increasing evidence shows that impaired telomere function is associated with male infertility, and various environmental factors are believed to play a pivotal role in telomerase deficiency and telomere shortening. Benzo[a]pyrene (B[a]P), a ubiquitous pollutant of polycyclic aromatic hydrocarbons (PAHs), can act as a reproductive toxicant; however, the adverse effect of B[a]P on telomeres in male ...
DOI:
10.1016/j.envpol.2017.12.099

20. Exposures to Atmospheric PM10 and PM10–2.5 Affect Male Semen Quality: Results of MARHCS Study

Author:
Cao, Jia,   et al.   ; Zhou, Niya; Jiang, Changtan; Chen, Qing; Yang, Huan; Wang, Xiaogang; Zou, Peng; Sun, Lei; Liu, Jiaojiao; Li, Ling; Li, Lianbing; Huang, Linping; Chen, Hongqiang; Ao, Lin; Zhou, Ziyuan; Liu, Jinyi; Cui, Zhihong;     Show all 17 Authors
Source:
Environmental science & technology 2018 v.52 no.3 pp. 1571-1581
ISSN:
1520-5851
Subject:
DNA; DNA fragmentation; air; air pollutants; air pollution; blood serum; estradiol; males; models; particulates; regression analysis; risk factors; semen quality; sperm concentration; spermatozoa; surveys; testosterone
Abstract:
... Studies have shown that the effects of ambient particulate matter (PM) may be related to particle’s size. However, results on the relationships between different PM and reproductive health are controversial. To explore the impacts of various PM fractions on male reproductive health, a total of 796 eligible subjects recruited in 2013 baseline investigation. In addition, there were 656 (82.4%) and 5 ...
DOI:
10.1021/acs.est.7b05206

21. Rearranged Phloroglucinol-Monoterpenoid Adducts from Callistemon rigidus

Author:
Cao, Jia-Qing,   et al.   ; Tian, Hai-Yan; Li, Man-Mei; Zhang, Wei; Wang, Ying; Wang, Lei; Ye, Wen-Cai;     Show all 7 Authors
Source:
Journal of natural products 2018 v.81 no.1 pp. 57-62
ISSN:
1520-6025
Subject:
Callistemon; X-ray diffraction; biochemical pathways; biosynthesis; inhibitory concentration 50; nitric oxide; terpenoids
Abstract:
... Callisretones A (1) and B (2), two rearranged phloroglucinol-monoterpenoid adducts featuring an unprecedented isopropylcyclopenta[b]benzofuran backbone, together with their postulated biosynthetic precursors (3–9), were isolated from Callistemon rigidus. The previously assigned absolute configurations of viminalins H (7), L (8), and N (9) were revised and unequivocally established by X-ray diffrac ...
DOI:
10.1021/acs.jnatprod.7b00606

22. Hyphospheric impacts of earthworms and arbuscular mycorrhizal fungus on soil bacterial community to promote oxytetracycline degradation

Author:
Cao, Jia,   et al.   ; Wang, Chong; Dou, Zhengxia; Liu, Mengli; Ji, Dingge;     Show all 5 Authors
Source:
Journal of hazardous materials 2018 v.341 pp. 346-354
ISSN:
0304-3894
Subject:
Flavobacteriaceae; Glycomyces; Nonomuraea; Pseudomonas; bacterial communities; earthworms; genes; hyphae; mycorrhizal fungi; oxytetracycline; ribosomal RNA; soil bacteria
Abstract:
... A two-compartment microcosm was used to investigate the role of arbuscular mycorrhizal fungus (AMF) hyphae and earthworm in altering soil microbial community and OTC degradation. Treatments comprised OTC-contaminated hyphal compartments with or without AMF hyphae and with or without earthworms. Results indicated both AMF hyphae and earthworms accelerated OTC degradation; two degradation products w ...
DOI:
10.1016/j.jhazmat.2017.07.038

23. Artificial Agrobacterium tumefaciens strains exhibit diverse mechanisms to repress Xanthomonas oryzae pv. oryzae‐induced hypersensitive response and non‐host resistance in Nicotiana benthamiana

Author:
Cao, Jia‐Yi,   et al.   ; Li, Wen; Xu, You‐Ping; Cai, Xin‐Zhong;     Show all 4 Authors
Source:
Molecular plant pathology 2017 v.18 no.4 pp. 489-502
ISSN:
1464-6722
Subject:
Agrobacterium radiobacter; Nicotiana benthamiana; antibacterial properties; antibiosis; antibiotics; genes; genotype; hydrogen peroxide; hypersensitive response; plasmids; transfer DNA; type III secretion system
Abstract:
... Xanthomonas oryzae pv. oryzae (Xoo) rapidly triggers a hypersensitive response (HR) and non‐host resistance in its non‐host plant Nicotiana benthamiana. Here, we report that Agrobacterium tumefaciens strain GV3101 blocks Xoo‐induced HR in N. benthamiana when pre‐infiltrated or co‐infiltrated, but not when post‐infiltrated at 4 h after Xoo inoculation. This suppression by A. tumefaciens is local an ...
DOI:
10.1111/mpp.12411

24. Myrtucomvalones A–C, three unusual triketone–sesquiterpene adducts from the leaves of Myrtus communis ‘Variegata’

Author:
Cao, Jia-Qing,   et al.   ; Chen, Ming; Chen, Li-Feng; Li, Man-Mei; Li, Ni-Ping; Wang, Ying; Li, Yao-Lan; Wang, Lei; Ye, Wen-Cai;     Show all 9 Authors
Source:
RSC advances 2017 v.7 no.37 pp. 22735-22740
ISSN:
2046-2069
Subject:
Myrtus communis; Respiratory syncytial virus; carbon; circular dichroism spectroscopy; leaves; spectral analysis
Abstract:
... Three new triketone–sesquiterpene adducts, myrtucomvalones A–C (1–3), along with four known compounds (4–7) were isolated from the leaves of Myrtus communis ‘Variegata’. Compounds 1 and 2 are the first examples of triketone–cubebane hybrids with an unusual carbon skeleton. Their structures with absolute configurations were determined by spectroscopic data, single crystal X-ray diffraction and elec ...
DOI:
10.1039/c7ra02260c

25. Metal-Free Synthesis of C-4 Substituted Pyridine Derivatives Using Pyridine-boryl Radicals via a Radical Addition/Coupling Mechanism: A Combined Computational and Experimental Study

Author:
Cao, Jia,   et al.   ; Wang, Guoqiang; Gao, Liuzhou; Chen, Wenxin; Huang, Wenhao; Cheng, Xu; Li, Shuhua;     Show all 7 Authors
Source:
Journal of the American Chemical Society 2017 v.139 no.10 pp. 3904-3910
ISSN:
1520-5126
Subject:
aldehydes; free radicals; ketones; methodology; pyridines
Abstract:
... Density functional theory investigations revealed that the pyridine-boryl radical generated in situ using 4-cyanopyridine and bis(pinacolato)diboron could be used as a bifunctional “reagent”, which serves as not only a pyridine precursor but also a boryl radical. With the unique reactivity of such radicals, 4-substituted pyridine derivatives could be synthesized using α,β-unsaturated ketones and 4 ...
DOI:
10.1021/jacs.7b00823

26. Polycyclic aromatic hydrocarbons exposure decreased sperm mitochondrial DNA copy number: A cross-sectional study (MARHCS) in Chongqing, China

Author:
Cao, Jia,   et al.   ; Ling, Xi; Zhang, Guowei; Sun, Lei; Wang, Zhi; Zou, Peng; Gao, Jianfang; Peng, Kaige; Chen, Qing; Yang, Huan; Zhou, Niya; Cui, Zhihong; Zhou, Ziyuan; Liu, Jinyi; Ao, Lin;     Show all 15 Authors
Source:
Environmental pollution 2017 v.220 pp. 680-687
ISSN:
0269-7491
Subject:
adverse effects; college students; creatinine; cross-sectional studies; males; membrane potential; metabolites; mitochondria; mitochondrial DNA; mitochondrial membrane; nuclear genome; pollutants; polycyclic aromatic hydrocarbons; spermatozoa; China
Abstract:
... Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental pollutants that have adverse effects on the male reproductive function. Many studies have confirmed that PAHs preferentially accumulate in mitochondria DNA relative to nuclear DNA and disrupt mitochondrial functions. However, it is rare whether exposure to PAHs is associated with mitochondrial damage and dysfunction in sperm. To ...
DOI:
10.1016/j.envpol.2016.10.026

27. Augmentation of acyl homoserine lactones-producing and -quenching bacterium into activated sludge for its granulation

Author:
Cao, Jia-Shun,   et al.   ; Li, Yu-Sheng; Pan, Xin-Rong; Song, Xiang-Ning; Fang, Fang; Tong, Zhong-Hua; Li, Wen-Wei; Yu, Han-Qing;     Show all 8 Authors
Source:
Water research 2017
ISSN:
0043-1354
Subject:
activated sludge; bacteria; bacterial communities; biofilm; biomass; bioreactors; community structure; economic feasibility; granules; homoserine; nutrients; physicochemical properties; quorum sensing; sequence analysis; wastewater treatment; zeta potential
Abstract:
... Quorum sensing (QS), especially acyl homoserine lactone (AHL)-mediated QS, in activated sludge arouses great interests because of its vital role in the formation of biofilm and aerobic granules (AG). Although QS is reported to be largely related to the properties of activated sludge, it is not economically feasible to tune QS in an activated sludge reactor through dosing pure AHL or AHL hydrolase. ...
DOI:
10.1016/j.watres.2017.08.061

28. Phthalate exposure, even below Environment-Protection-Agency reference doses, was associated with semen quality and reproductive hormones: Prospective MARHCS study in general population

Author:
Cao, Jia,   et al.   ; Chen, Qing; Yang, Huan; Zhou, Niya; Sun, Lei; Bao, Huaqiong; Tan, Lu; Chen, Hongqiang; Ling, Xi; Zhang, Guowei; Huang, Linping; Li, Lianbing; Ma, Mingfu; Yang, Hao; Wang, Xiaogang; Zou, Peng; Peng, Kaige; Liu, Taixiu; Shi, Xiefei; Feng, Dejian; Cui, Zhihong; Ao, Lin; Zhou, Ziyuan;     Show all 23 Authors
Source:
Environment international 2017
ISSN:
0160-4120
Subject:
United States Environmental Protection Agency; blood serum; environmental exposure; estradiol; follicle-stimulating hormone; human population; luteinization; luteinizing hormone; males; metabolites; phthalates; progesterone; prolactin; semen quality; sperm concentration; spermatozoa; testosterone; toxicity; urine
Abstract:
... Environment-Protection-Agency Reference Doses (EPA RfDs) for phthalate intakes are based on limited evidence, especially regarding low-dose male-reproductive toxicity. This study investigates the association between phthalate exposure and semen parameters and reproductive hormones in a general population with low phthalate exposure compared to the EPA RfDs.The MARHCS (Male-Reproductive-Health-in-C ...
DOI:
10.1016/j.envint.2017.04.005

29. Identification of major loci for seed dormancy at different post-ripening stages after harvest and validation of a novel locus on chromosome 2AL in common wheat

Author:
Cao, Jia-Jia,   et al.   ; Zhu, Yu-Lei; Wang, Sheng-Xing; Zhang, Hai-Ping; Zhao, Liang-Xia; Wu, Zeng-Yun; Jiang, Hao; Liu, Kai; Qin, Meng; Lu, Jie; Sun, Gen-Lou; Xia, Xian-Chun; Chang, Cheng; Ma, Chuan-Xi;     Show all 14 Authors
Source:
Molecular breeding 2016 v.36 no.12 pp. 174
ISSN:
1380-3743
Subject:
Triticum aestivum; genes; germination; germplasm; humidity; inbred lines; linear models; loci; marker-assisted selection; microsatellite repeats; quantitative trait loci; rain; seed dormancy; sprouting; vivipary (plants); wheat
Abstract:
... A long-period duration of seed dormancy helps to reduce pre-harvest sprouting (PHS) damage in common wheat when a long period of rainfall or high humidity occurs. Identification of genes or loci underlying seed dormancy duration is of high importance for investigating genetic mechanism of PHS tolerance of wheat. In the present study, the germination index (GI) of different mapping populations at 5 ...
DOI:
10.1007/s11032-016-0598-0

30. Removal of heavy metal Cu(II) in simulated aquaculture wastewater by modified palygorskite

Author:
Cao, Jia-Shun,   et al.   ; Wang, Cheng; Fang, Fang; Lin, Jun-Xiong;     Show all 4 Authors
Source:
Environmental pollution 2016 v.219 pp. 924-931
ISSN:
0269-7491
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; X-ray photoelectron spectroscopy; adsorbents; adsorption; chelation; copper; cost effectiveness; electrostatic interactions; energy-dispersive X-ray analysis; heavy metals; models; pH; palygorskite; scanning electron microscopes; sorption isotherms; surface area; temperature; thermodynamics; thermogravimetry; transmission electron microscopy; wastewater aquaculture; wastewater treatment
Abstract:
... Palygorskite (PAL) is a good heavy metal adsorbent due to its high surface area, low cost, and environmentally compatibility. But the natural PAL has limited its adsorption capacity and selectivity. In this study, a cost-effective and readily-generated absorbent, l-threonine-modified palygorskite (L-PAL), was used and its performance for Cu(II) removal in simulated aquaculture wastewater was evalu ...
DOI:
10.1016/j.envpol.2016.09.014

31. Improvement of the soil nitrogen content and maize growth by earthworms and arbuscular mycorrhizal fungi in soils polluted by oxytetracycline

Author:
Cao, Jia,   et al.   ; Wang, Chong; Ji, Dingge;     Show all 3 Authors
Source:
The Science of the total environment 2016 v.571 pp. 926-934
ISSN:
0048-9697
Subject:
Eisenia fetida; agroecosystems; ammonia; bacteria; biomass; corn; earthworms; mycorrhizal fungi; nitrogen; nitrogen content; oxidants; oxytetracycline; planting; polluted soils; pollution; roots; shoots; urease
Abstract:
... Interactions between earthworms (Eisenia fetida) and arbuscular mycorrhizal fungi (Rhizophagus intraradices, AM fungi) have been suggested to improve the maize nitrogen (N) content and biomass and were studied in soils polluted by oxytetracycline (OTC). Maize was planted and amended with AMF and/or earthworms (E) in the soil with low (1mgkg−1 soil DM) or high (100mgkg−1 soil DM) amounts of OTC pol ...
DOI:
10.1016/j.scitotenv.2016.07.077

32. Effect of earthworms and arbuscular mycorrhizal fungi on the microbial community and maize growth under salt stress

Author:
Cao, Jia,   et al.   ; Zhang, Wenwen; Zhang, Shudong; Wang, Chong;     Show all 4 Authors
Source:
Applied soil ecology 2016 v.107 pp. 214-223
ISSN:
0929-1393
Subject:
Stachybotrys; Trichoderma; absorption; bacteria; catalase; corn; earthworms; electrical conductivity; microbial activity; microbial biomass; microbial communities; mycorrhizal fungi; nitrogen; phosphorus; potassium; roots; salinity; salt stress; shoots; soil conditioners; soil organic carbon; soil pH; vesicular arbuscular mycorrhizae
Abstract:
... The aim of this study was to investigate the independent and interactive effectiveness of epigeic earthworms and arbuscular mycorrhizal (AM) fungi as soil conditioners in modifying the properties of salt-affected soil and increasing maize productivity. Treatments included maize plants inoculated vs. not inoculated with AM fungi and treated with or without earthworms. The mycorrhizal colonization, ...
DOI:
10.1016/j.apsoil.2016.06.005

33. Cloning and characterization of Tabas1-B1 gene associated with flag leaf chlorophyll content and thousand-grain weight and development of a gene-specific marker in wheat

Author:
Cao, Jia-Jia,   et al.   ; Zhu, Xiao-Feng; Zhang, Hai-Ping; Hu, Ming-Jian; Wu, Zeng-Yun; Jiang, Hao; Xia, Xian-Chun; Ma, Chuan-Xi; Chang, Cheng;     Show all 9 Authors
Source:
Molecular breeding 2016 v.36 no.10 pp. 142
ISSN:
1380-3743
Subject:
Triticum aestivum; alleles; breeding; chlorophyll; chloroplasts; exons; geographical distribution; grain crops; introns; leaves; loci; open reading frames; peroxiredoxin; phenotypic variation; photosynthates; quantitative trait loci; wheat; China
Abstract:
... The chloroplast photosystem of flag leaves contributes the largest proportion of photosynthates to grain in crops and consequently affects grain weight. The plant 2-Cys peroxiredoxin BAS1 is involved in chlorophyll protection against chloroplast damage. In the present study, we cloned a Tabas1 gene in common wheat (Triticum aestivum L.), comprising seven exons and six introns with a complete seque ...
DOI:
10.1007/s11032-016-0563-y

34. Shorter sperm telomere length in association with exposure to polycyclic aromatic hydrocarbons: Results from the MARHCS cohort study in Chongqing, China and in vivo animal experiments

Author:
Cao, Jia,   et al.   ; Ling, Xi; Zhang, Guowei; Chen, Qing; Yang, Huan; Sun, Lei; Zhou, Niya; Wang, Zhi; Zou, Peng; Wang, Xiaogang; Cui, Zhihong; Liu, Jinyi; Ao, Lin;     Show all 13 Authors
Source:
Environment international 2016 v.95 pp. 79-85
ISSN:
0160-4120
Subject:
adverse effects; animal experimentation; apoptosis; benzo(a)pyrene; biomarkers; cohort studies; college students; dose response; environmental exposure; humans; male fertility; males; metabolites; polycyclic aromatic hydrocarbons; questionnaires; rats; regression analysis; reproductive toxicology; semen; spermatozoa; telomerase; telomeres; volunteers; China
Abstract:
... It has been well demonstrated that polycyclic aromatic hydrocarbons (PAHs) can cause reproductive toxicity, and shorter telomere length in sperm may be one of the factors causing male infertility. However, whether exposure to PAHs is associated with sperm telomere length (STL) has never been evaluated. The present study aimed to assess the potential association between PAHs exposure and STL, and t ...
DOI:
10.1016/j.envint.2016.08.001

35. Tight regulation of the interaction between Brassica napus and Sclerotinia sclerotiorum at the microRNA level

Author:
Cao, Jia-Yi,   et al.   ; Xu, You-Ping; Zhao, Li; Li, Shuang-Sheng; Cai, Xin-Zhong;     Show all 5 Authors
Source:
Plant molecular biology 2016 v.92 no.1-2 pp. 39-55
ISSN:
0167-4412
Subject:
Arabidopsis; Brassica napus; RNA interference; Sclerotinia sclerotiorum; genes; genetically modified organisms; high-throughput nucleotide sequencing; leaves; microRNA; microarray technology; mutants; oil crops; oilseed crops; oxygen; pathogens; reactive oxygen species
Abstract:
... MicroRNAs (miRNAs) are multifunctional non-coding short nucleotide molecules. Nevertheless, the role of miRNAs in the interactions between plants and necrotrophic pathogens is largely unknown. Here, we report the identification of the miRNA repertoire of the economically important oil crop oilseed rape (Brassica napus) and those involved in interacting with its most devastating necrotrophic pathog ...
DOI:
10.1007/s11103-016-0494-3

36. Sleeping Beauty transposon-based system for rapid generation of HBV-replicating stable cell lines

Author:
Cao, Jia-Li,   et al.   ; Wu, Yong; Zhang, Tian-Ying; Fang, Lin-lin; Chen, Zi-Xuan; Song, Liu-Wei; Yang, Lin; Yuan, Quan; Xia, Ning-Shao;     Show all 9 Authors
Source:
Journal of virological methods 2016 v.234 pp. 96-100
ISSN:
0166-0934
Subject:
antiviral agents; flow cytometry; genotype; human cell lines; plasmids; protein synthesis; puromycin; red fluorescent protein; resistance genes; transfection; transposons
Abstract:
... The stable HBV-replicating cell lines, which carry replication-competent HBV genome stably integrated into the genome of host cell, are widely used to evaluate the effects of antiviral agents. However, current methods to generate HBV-replicating cell lines, which are mostly dependent on random integration of foreign DNA via plasmid transfection, are less-efficient and time-consuming. To address th ...
DOI:
10.1016/j.jviromet.2016.04.010

37. Sunlight-promoted cyclization versus decarboxylation in the reaction of alkynoates with N-iodosuccinimide: easy access to 3-iodocoumarins

Author:
Cao, Jia,   et al.   ; Ni, Shengyang; Mei, Haibo; Han, Jianlin; Li, Shuhua; Pan, Yi;     Show all 6 Authors
Source:
Green chemistry 2016 v.18 no.14 pp. 3935-3939
ISSN:
1463-9270
Subject:
X-radiation; catalysts; decarboxylation; green chemistry; iodination; iodine; solar radiation
Abstract:
... A sunlight-initiated radical conversion of aryl alkynoates to 3-iodocoumarins has been achieved using N-iodosuccinimide as the iodine source without the use of a catalyst or additive. Experimental, X-ray analysis, and computational studies indicate that the reaction under sunlight proceeds through iodination, spirocyclization and ring expansion to form the kinetic product. The sunlight-driven reac ...
DOI:
10.1039/c6gc01027j

38. Independent and combined effects of oxytetracycline and antibiotic-resistant Escherichia coli O157:H7 on soil microbial activity and partial nitrification processes

Author:
Cao, Jia,   et al.   ; Wang, Chong; Dou, Zhengxia; Ji, Dingge;     Show all 4 Authors
Source:
Soil biology & biochemistry 2016 v.98 pp. 138-147
ISSN:
0038-0717
Subject:
Escherichia coli O157; agricultural land; animal manures; antibiotic resistance; genes; microbial activity; nitrate nitrogen; nitrification; oxytetracycline; pathogens; ribosomal RNA; soil; soil bacteria; soil inoculation; urease
Abstract:
... The common practice of field-spreading animal manure on agricultural land contributes to the dissemination of antibiotics and antibiotic-resistant pathogens, which may disrupt important soil microbial functions. In this study, the potential independent and combined effects of oxytetracycline (OTC) and antibiotic-resistant Escherichia coli O157:H7 (E. coli O157:H7) on soil microbial activity and pa ...
DOI:
10.1016/j.soilbio.2016.03.014

39. TMT-based quantitative proteomics analyses reveal novel defense mechanisms of Brassica napus against the devastating necrotrophic pathogen Sclerotinia sclerotiorum

Author:
Cao, Jia-Yi,   et al.   ; Xu, You-Ping; Cai, Xin-Zhong;     Show all 3 Authors
Source:
Journal of proteomics 2016 v.143 pp. 265-277
ISSN:
1874-3919
Subject:
Brassica napus; DNA; Sclerotinia sclerotiorum; agar; calcium signaling; defense mechanisms; gene expression regulation; genes; histones; homeostasis; leaves; lipids; mutants; pathogens; prediction; protein-protein interactions; proteomics; quantitative analysis; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; transcription (genetics)
Abstract:
... The white mould disease, caused by Sclerotinia sclerotiorum, is one of the most important diseases in the vital oil crop Brassica napus. Nevertheless, the defense mechanisms of B. napus against S. sclerotiorum are poorly understood. In this study, we performed comparative quantitative proteomics analyses to reveal B. napus defense mechanisms against S. sclerotiorum. The proteomes of B. napus leave ...
DOI:
10.1016/j.jprot.2016.03.006

40. Evaluation of Trace Elements and Their Relationship with Growth and Development of Young Children

Author:
Cao, Jia,   et al.   ; Gao, Zhenyan; Yan, Jin; Li, Minming; Su, Jia; Xu, Jian; Yan, Chong-Huai;     Show all 7 Authors
Source:
Biological trace element research 2016 v.171 no.2 pp. 270-274
ISSN:
0163-4984
Subject:
atomic absorption spectrometry; blood; blood sampling; body mass index; calcium; children; copper; correlation; dietary supplements; growth and development; iron; magnesium; nutrition assessment; nutritional status; screening; zinc; China
Abstract:
... This study was conducted to assess the levels of trace elements and their relationship with growth and development of children in Shanghai, China, to offer scientific evidence for supplementing trace elements in children. A stratified, clustered, random sampling method was used in the study. Blood samples were taken from 2141 Shanghai children from 0 to 6.0 years old, and the concentrations of zin ...
DOI:
10.1007/s12011-015-0537-7

41. The effect of two cryopreservation methods on human sperm DNA damage

Author:
Cao, Jia,   et al.   ; Liu, Taixiu; Gao, Jianfang; Zhou, Niya; Mo, Min; Wang, Xiaogang; Zhang, Xi; Yang, Huan; Chen, Qing; Ao, Lin; Liu, Jinyi; Cui, Zhihong;     Show all 12 Authors
Source:
Cryobiology 2016 v.72 pp. 210-215
ISSN:
0011-2240
Subject:
DNA; DNA damage; chromatin; college students; cryopreservation; cryoprotectants; freeze-thaw cycles; freezing; gel electrophoresis; humans; nitrogen; refrigerators; semen; spermatozoa; temperature; thawing
Abstract:
... Several methods are currently available for selection when conducting sperm cryopreservation, however, these methods might cause different degrees of damage on sperm DNA. The aim of the this study is to compare the effects of storage at −80 °C (in ultra-low temperature refrigerator) and at −196 °C (in liquid nitrogen) on sperm DNA damage, thus to provide a reference for choosing the right method a ...
DOI:
10.1016/j.cryobiol.2016.04.004

42. Effects of cell phone use on semen parameters: Results from the MARHCS cohort study in Chongqing, China

Author:
Cao, Jia,   et al.   ; Zhang, Guowei; Yan, Huan; Chen, Qing; Liu, Kaijun; Ling, Xi; Sun, Lei; Zhou, Niya; Wang, Zhi; Zou, Peng; Wang, Xiaogang; Tan, Lu; Cui, Zhihong; Zhou, Ziyuan; Liu, Jinyi; Ao, Lin;     Show all 16 Authors
Source:
Environment international 2016 v.91 pp. 116-121
ISSN:
0160-4120
Subject:
semen; men; cohort studies; males; regression analysis; confidence interval; sperm concentration; college students; male fertility; spermatozoa; Internet; statistical models; China
Abstract:
... Epidemiological and experimental evidence for detrimental effects of cell phone use on semen quality is still equivocal. And that recruiting participants from infertility clinic not from general population may raise the possibility of a selection bias. To investigate effects of cell phone use on semen parameters in a general population,We screened and documented the cell phone use information of 7 ...
DOI:
10.1016/j.envint.2016.02.028

43. Preparation and characterization of alginate/HACC/oyster shell powder biocomposite scaffolds for potential bone tissue engineering applications

Author:
Cao, Jia-lin,   et al.   ; Chen, Tai-ying; Huang, Hao-chao; Xin, Yan-jiao; Luo, Wen-feng; Ao, Ning-jian;     Show all 6 Authors
Source:
RSC advances 2016 v.6 no.42 pp. 35577-35588
ISSN:
2046-2069
Subject:
Escherichia coli; Fourier transform infrared spectroscopy; Staphylococcus aureus; adsorption; alginates; alkaline phosphatase; antibacterial properties; biocomposites; biodegradability; biodegradation; biomineralization; biopolymers; bones; chitosan; compression strength; cytotoxicity; freeze drying; mechanical testing; mixing; oyster shells; porosity; scanning electron microscopy; surface area; tissue engineering
Abstract:
... Tissue engineering scaffolds combining biominerals and natural polymers are prospective candidates for bone repair materials. In this work, biocompatible and antibacterial scaffolds were prepared by blending alginate, hydroxypropyl trimethyl ammonium chloride chitosan (HACC) and oyster shell powder (OSP) by freeze drying. SEM, FTIR, mechanical testing and BET surface area analysis were applied to ...
DOI:
10.1039/c5ra26805b

44. Characterization of an IAA-glucose hydrolase gene TaTGW6 associated with grain weight in common wheat (Triticum aestivum L.)

Author:
Cao, Jia-Jia,   et al.   ; Hu, Ming-Jian; Zhang, Hai-Ping; Zhu, Xiao-Feng; Wang, Sheng-Xing; Jiang, Hao; Wu, Zeng Yun; Lu, Jie; Chang, Cheng; Sun, Gen-Lou; Ma, Chuan-Xi;     Show all 11 Authors
Source:
Molecular breeding 2016 v.36 no.3 pp. 25
ISSN:
1380-3743
Subject:
Triticum aestivum; alleles; exons; genetic distance; inbred lines; indole acetic acid; loci; marker-assisted selection; microsatellite repeats; mutants; open reading frames; phenotypic variation; quantitative polymerase chain reaction; rice; seed development; sequence analysis; start codon; wheat
Abstract:
... In rice, the TGW6 gene determines grain weight and encodes a protein with indole-3-acetic acid (IAA)-glucose hydrolase activity. Its homolog in wheat, TaTGW6, is considered as a candidate gene related to grain development. To amplify this gene, we designed primers based on a homologous conserved domain of the rice TGW6 gene. Sequence analysis indicated that TaTGW6 comprises only one exon, with 165 ...
DOI:
10.1007/s11032-016-0449-z

45. Synergism/Antagonism between Crude Oil Fractions and Novel Betaine Solutions in Reducing Interfacial Tension

Author:
Cao, Jia-Hua,   et al.   ; Zhou, Zhao-Hui; Xu, Zhi-Cheng; Zhang, Qun; Li, Shi-Hong; Cui, Hai-Bin; Zhang, Lei; Zhang, Lu;     Show all 8 Authors
Source:
Energy & Fuels 2016 v.30 no.2 pp. 924-932
ISSN:
1520-5029
Subject:
adsorption; alkanes; aromatic compounds; betaine; ethanol; hydrophobicity; kerosene; petroleum; resins; sodium hydroxide; surface tension; surfactants; synergism
Abstract:
... The Shengli crude oil fractions of saturates, aromatics, resins, and asphaltenes (SARA) were obtained by the classic SARA method, and acidic fractions were extracted by ethanol/water (7:3, v/v) solution mixed with 1.5 mass % NaOH. The interfacial tensions (IFTs) of solutions of two different betaines with different structures against n-alkanes, kerosene, and crude oil fractions dissolved in kerose ...
DOI:
10.1021/acs.energyfuels.5b02566

46. Two new isoaurones derivatives from Callistephus chinensis flower

Author:
Cao, Jia-qing,   et al.   ; Zhang, Xiao-shu; Shi, Guo-hui; Liu, Zhen-ting; Liu, Jing-xin; Zhao, Yu-qing;     Show all 6 Authors
Source:
Natural product research 2016 v.30 no.3 pp. 358-361
ISSN:
1478-6427
Subject:
Callistephus chinensis; cytotoxicity; flowers; nuclear magnetic resonance spectroscopy; spectral analysis
Abstract:
... Two new isoaurones derivatives were obtained from Callistephus chinensis flower. Their structures were elucidated on the basis of extensive spectroscopic analyses. Both of the new compounds were evaluated cytotoxic activity. Phytochemical investigation of Callistephus chinensis flower led to the isolation of two new isoaurones derivatives (Z)-4′,4,10-trihydroxy-siamaurone (1) and (E)-4′,4,10-trihy ...
DOI:
10.1080/14786419.2015.1053090

47. Outcompeting Presence of Acyl-Homoserine-Lactone (AHL)-Quenching Bacteria over AHL-Producing Bacteria in Aerobic Granules

Author:
Cao, Jia-Shun,   et al.   ; Li, Yu-Sheng; Li, Bing-Bing; Li, Wen-Wei; Fang, Fang; Tong, Zhong-Hua; Yu, Han-Qing;     Show all 7 Authors
Source:
Environmental Science & Technology Letters 2016 v.3 no.1 pp. 36-40
ISSN:
2328-8930
Subject:
Bacillus (bacteria); Sphingomonas; bacteria; biofilm; granules; quorum sensing; wastewater treatment
Abstract:
... The roles of acyl-homoserine-lactone (AHL)-based quorum sensing in biofilm formation for biological wastewater treatment have been widely recognized. In previous studies about the role of AHLs in biofilm formation, the focus is always on AHL-producing bacteria, while attention to AHL-quenching bacteria is not paid. In this work, 600 microbial isolates were screened from aerobic granules, a special ...
DOI:
10.1021/acs.estlett.5b00332

48. Callistrilones A and B, Triketone–Phloroglucinol–Monoterpene Hybrids with a New Skeleton from Callistemon rigidus

Author:
Cao, Jia-Qing,   et al.   ; Huang, Xiao-Jun; Li, Yu-Ting; Wang, Ying; Wang, Lei; Jiang, Ren-Wang; Ye, Wen-Cai;     Show all 7 Authors
Source:
Organic letters 2016 v.18 no.1 pp. 120-123
ISSN:
1523-7052
Subject:
Callistemon; Gram-positive bacteria; X-ray diffraction; antibacterial properties; carbon; chemical reactions; chemical structure; circular dichroism spectroscopy; leaves; organic compounds; spectral analysis
Abstract:
... The first triketone–phloroglucinol–monoterpene hybrids, callistrilones A and B (1 and 2), along with a postulated biosynthetic intermediate (3) were isolated from the leaves of Callistemon rigidus. Compounds 1 and 2 featured a new carbon skeleton with an unprecedented [1]benzofuro[2,3-a]xanthene or [1]benzofuro[3,2-b]xanthene pentacyclic ring system composed of three kinds of building blocks. Thei ...
DOI:
10.1021/acs.orglett.5b03360

49. Interaction between earthworms and arbuscular mycorrhizal fungi on the degradation of oxytetracycline in soils

Author:
Cao, Jia,   et al.   ; Ji, Dingge; Wang, Chong;     Show all 3 Authors
Source:
Soil biology & biochemistry 2015 v.90 pp. 283-292
ISSN:
0038-0717
Subject:
Bacillus cereus; Chaetomium; Eisenia fetida; Hyphomicrobium; Thielavia; bacteria; catalase; corn; earthworms; enzyme activity; greenhouse production; hyphae; microbial biomass; microbial communities; mycorrhizae; mycorrhizal fungi; oxytetracycline; soil; soil enzymes; urease
Abstract:
... The interactive impact of earthworms (Eisenia fetida) and arbuscular mycorrhizal fungi (Rhizophagus intraradices, AM fungi) on the degradation of oxytetracycline (OTC) in soils was studied under greenhouse conditions. Treatments included maize plants inoculated vs. not inoculated with AM fungi and treated with or without earthworms at low (1 mg kg−1 soil DM) or high (100 mg kg−1 soil DM) OTC rates ...
DOI:
10.1016/j.soilbio.2015.08.020

50. Interactive impacts of earthworms (Eisenia fetida) and arbuscular mycorrhizal fungi (Funneliformis mosseae) on the bioavailability of calcium phosphates

Author:
Cao, Jia,   et al.   ; Wang, Chong; Huang, Yan;     Show all 3 Authors
Source:
Plant and soil 2015 v.396 no.1-2 pp. 45-57
ISSN:
0032-079X
Subject:
Eisenia fetida; Flavobacteriaceae; Glomus mosseae; Zea mays; bacterial communities; beta-Proteobacteria; bioavailability; calcium; calcium phosphates; corn; earthworms; hyphae; ions; microbial biomass; mycorrhizal fungi; nitrogen; nutrient uptake; phosphorus; potassium; roots; shoots; soil bacteria; soil pH
Abstract:
... BACKGROUND AND AIMS: The positive interactive impacts of arbuscular mycorrhizal fungi (Funneliformis mosseae) and earthworms (Eisenia fetida) on increasing calcium phosphate availability, AM hyphal contribution to maize (Zea mays L.) P uptake and utilization efficiency of calcium phosphate-P by maize were studied in the Organization for Economic Co-operation and Development (OECD) artificial soil ...
DOI:
10.1007/s11104-015-2588-0

51. Rhizosphere interactions between earthworms (Eisenia fetida) and arbuscular mycorrhizal fungus (Funneliformis mosseae) promote utilization efficiency of phytate phosphorus in maize

Author:
Cao, Jia,   et al.   ; Huang, Yan; Wang, Chong;     Show all 3 Authors
Source:
Applied soil ecology 2015 v.94 pp. 30-39
ISSN:
0929-1393
Subject:
Eisenia fetida; Flavobacteriaceae; Glomus mosseae; Xanthomonadales; alkaline phosphatase; alkaline soils; bacteria; bacterial communities; beta-Proteobacteria; corn; correlation; earthworms; microbial biomass; mineralization; mycorrhizal fungi; phosphorus; phytic acid; planting; rhizosphere; roots; shoots
Abstract:
... Rhizosphere interactions between earthworms (Eisenia fetida) and arbuscular mycorrhizal fungus (AMF, Funneliformis mosseae), suggested to promote phytate mineralization and maize phosphorus (P) content were studied in the Organization for Economic Co-operation and Development (OECD) (non-phosphorus active soil). Maize was planted and amended with AMF and/or earthworms (E) as well as insoluble phyt ...
DOI:
10.1016/j.apsoil.2015.05.001

52. Effects of metabolic uncouplers on excess sludge reduction and microbial products of activated sludge

Author:
Cao, Jia-Shun,   et al.   ; Fang, Fang; Hu, Hai-Lan; Qin, Min-Min; Xue, Zhao-Xia; Hu, Zhi-Rong;     Show all 6 Authors
Source:
Bioresource technology 2015 v.185 pp. 1-6
ISSN:
0960-8524
Subject:
activated sludge; ammonia; chemical oxygen demand; polyhydroxybutyrate; polysaccharides; protein content; storage
Abstract:
... The present study investigated the influences of three metabolic uncouplers (pCP, oCP and oNP) on excess activated sludge reduction and microbial products of extracellular polymeric substances (EPS) and intracellular storage product (polyhydroxybutyrate, PHB) in short-term tests. Results showed sludge was reduced 58.2%, 59.8% and 80.8%, respectively, at pCP, oCP and oNP concentrations of 20mg/L. T ...
DOI:
10.1016/j.biortech.2015.02.054

53. Spatial distribution, sources and ecological risk assessment of polycyclic aromatic hydrocarbons in surface seawater from Yangpu Bay, China

Author:
Cao, Jia,   et al.   ; Li, Ping; Diao, Xiaoping; Wang, Baihua; Zhou, Hailong; Han, Qian; Zheng, Pengfei; Li, Yuhu;     Show all 8 Authors
Source:
Marine pollution bulletin 2015 v.93 no.1-2 pp. 53-60
ISSN:
0025-326X
Subject:
United States Environmental Protection Agency; coasts; environmental assessment; polycyclic aromatic hydrocarbons; risk; risk assessment; seawater; summer; water pollution; winter; China
Abstract:
... The occurrence of 14 polycyclic aromatic hydrocarbons (PAHs) listed by the United States Environmental Protection Agency was investigated in surface seawater of Yangpu Bay, China in November 2013 (winter) and May 2014 (summer). Seventy-two samples were collected from 12 sampling sites. The total concentrations of PAHs in Yangpu Bay showed obvious variations in different seasons, which varied from ...
DOI:
10.1016/j.marpolbul.2015.02.015

54. Over‐expression of GhUGP1 in upland cotton improves fibre quality and reduces fibre sugar content

Author:
Cao, Jia‐Qiang,   et al.   ; Li, Bo; Yang, Yang; Hu, Wen‐Ran; Li, Xiao‐Dong; Fan, Ling; Jenkins, J.;     Show all 7 Authors
Source:
Plant breeding 2015 v.134 no.2 pp. 197-202
ISSN:
0179-9541
Subject:
Gossypium hirsutum; Southern blotting; autumn; cellulose; fiber quality; gene expression; glucose; homozygosity; kanamycin; lint cotton; oligosaccharides; polymerase chain reaction; proteins; sugar content; temperature; transcription (genetics); transgenic plants; uridine diphosphate
Abstract:
... GhUGP1 (cotton uridine diphosphate glucose pyrophosphorylase) is one of the most highly expressed genes and proteins in fast elongation cotton fibres. The objective of this study was to determine whether fibre quality and reduced sugar content could be improved in fibres by over‐expressing GhUGP1 in cotton plants under conditions of low autumn temperatures and large diurnal temperature differences ...
DOI:
10.1111/pbr.12247

55. Callistephus A, a novel sesquiterpene from the Callistephus chinensis flower

Author:
Cao, Jia-qing,   et al.   ; Zhang, Xiao-shu; Liu, Zhen-ting; Yuan, Lei; Chen, Gang; Liu, Jing-xin; Qu, Fan-zhi; Zhao, Yu-qing;     Show all 8 Authors
Source:
Phytochemistry letters 2015 v.11 pp. 5-8
ISSN:
1874-3900
Subject:
Callistephus chinensis; X-ray diffraction; biogenesis; carbon; flowers; sesquiterpenoids; spectral analysis
Abstract:
... Two new compounds callistephus A (1) and callistephus B (2) together with 4,6-dihydroxyphenyl-1-butanone-2-β-d-O-glucopyranoside (3), were isolated and purified from the Callistephus chinensis flower. Their structures were identified by the interpretation of spectroscopic data. X-ray crystallographic and analysis of quantum chemical ECD calculation were applied to determine the absolute configurat ...
DOI:
10.1016/j.phytol.2014.10.030

56. Three new triterpene saponins from Actinostemma lobatum MAXIM and their cytotoxicity in vitro

Author:
Cao, Jia-qing,   et al.   ; Li, Wei; Tang, Yun; Zhang, Xiang-rong; Li, Wei; Zhao, Yu-qing;     Show all 6 Authors
Source:
Phytochemistry letters 2015 v.11 pp. 301-305
ISSN:
1874-3900
Subject:
cytotoxicity; spectral analysis; triterpenoid saponins
Abstract:
... Three new triterpene saponins, lobatoside O (1), actinostemmoside I (2) and actinostemmoside J (3), were isolated from the herb of Actinostemma lobatum MAXIM. Their structures were elucidated by means of extensive chemical and spectroscopic methods. In addition, cytotoxic activities toward HCT-116, HT-29, MCF-7 and A549 cell lines were tested by the MTT method. ...
DOI:
10.1016/j.phytol.2015.01.016

57. The national trend of blood lead levels among Chinese children aged 0–18years old, 1990–2012

Author:
Cao, Jia,   et al.   ; Li, Min-ming; Xu, Jian; Cai, Shi-zhong; Shen, Xiao-ming; Yan, Chong-huai;     Show all 6 Authors
Source:
Environment international 2014 v.71 pp. 109-117
ISSN:
0160-4120
Subject:
Chinese people; arithmetics; at-risk population; blood; children; data collection; databases; epidemiological studies; females; geometry; issues and policy; lead; lead poisoning; males; neonates; patients; pollution; quality control; regression analysis; China
Abstract:
... We analyzed the epidemiological data during 1990–2012 that investigated the blood lead level (BLL) in the population aged 0–18years old in China mainland and provided evidence of the benefits of implementing policies to prevent lead pollution based on the dynamic changes of BLL. Data were collected through databases including China Knowledge Resource Integrated Database (CNKI), CBM disc, Wanfang D ...
DOI:
10.1016/j.envint.2014.06.005

58. Silver-catalyzed 2-isocyanobiaryls insertion/cyclization with phosphine oxides: synthesis of 6-phosphorylated phenanthridines

Author:
Cao, Jia-Jia,   et al.   ; Zhu, Tong-Hao; Gu, Zheng-Yang; Hao, Wen-Juan; Wang, Shun-Yi; Ji, Shun-Jun;     Show all 6 Authors
Source:
Tetrahedron 2014 v.70 pp. 6985-6990
ISSN:
0040-4020
Subject:
chemical reactions; chemical structure; oxides; phenanthridines; phosphine
Abstract:
... A silver-catalyzed 2-isocyanobiaryls insertion/cyclization with phosphine oxides was described for the construction of the 6-phosphorylated phenanthridines through radical addition of in situ formed P-centered radical to 2-isocyanobiphenyls and homolytic aromatic substitution process. The reactions could proceed smoothly to give the desired 6-phosphorylated phenanthridines promoted by AgOAc (20 mo ...
DOI:
10.1016/j.tet.2014.07.078

59. A new absorbent by modifying walnut shell for the removal of anionic dye: Kinetic and thermodynamic studies

Author:
Cao, Jia-Shun,   et al.   ; Lin, Jun-Xiong; Fang, Fang; Zhang, Ming-Ting; Hu, Zhi-Rong;     Show all 5 Authors
Source:
Bioresource technology 2014 v.163 pp. 199-205
ISSN:
0960-8524
Subject:
Fourier transform infrared spectroscopy; adsorbents; adsorption; azo dyes; biosorbents; cross-linking reagents; epichlorohydrins; equations; models; pH; raw materials; scanning electron microscopes; thermodynamics; thermogravimetry; walnuts; wastewater treatment
Abstract:
... A novel, low cost and easy regeneration biosorbent, chem-modified walnut shell (MWNS), was studied to investigate its potential for removal of an anionic dye, reactive brilliant red K-2BP. The MWNS was synthesized with epichlorohydrin and diethylenetriamine as etherifying agent and crosslinking agent, respectively, and its characteristics were performed with Fourier transform infrared spectroscopy ...
DOI:
10.1016/j.biortech.2014.04.046

60. Characteristics of extracellular polymeric substances of phototrophic biofilms at different aquatic habitats

Author:
Cao, Jia-Shun,   et al.   ; Fang, Fang; Lu, Wen-Tao; Shan, Qi;     Show all 4 Authors
Source:
Carbohydrate polymers 2014 v.106 pp. 1-6
ISSN:
0144-8617
Subject:
Bacillariophyceae; Chlorophyta; algae; aquatic habitat; biofilm; biomass; drinking water; environmental factors; fluorescence emission spectroscopy; lakes; polysaccharides; wastewater treatment
Abstract:
... Three different phototrophic biofilms obtained from a natural lake (Sample 1), drinking water plant (Sample 2) and wastewater treatment plant (Sample 3) were investigated. Diatoms and green algae were the dominant algae of three biofilms, and the biomass was highest in biofilm of Sample 2. The three phototrophic biofilms also had variable extracellular polymeric substances (EPS) concentrations and ...
DOI:
10.1016/j.carbpol.2014.02.010

61. Curcusone D, a novel ubiquitin–proteasome pathway inhibitor via ROS-induced DUB inhibition, is synergistic with bortezomib against multiple myeloma cell growth

Author:
Cao, Jia-Yi,   et al.   ; Cao, Mei-Na; Zhou, Yu-Bo; Gao, An-Hui; Gao, Li-Xin; Sheng, Li; Xu, Lei; Su, Ming-Bo; Cao, Xian-Chao; Han, Meng-meng; Wang, Ming-Kui; Li, Jia;     Show all 12 Authors
Source:
BBA - General Subjects 2014 v.1840 pp. 2004-2013
ISSN:
0304-4165
Subject:
NAD ADP-ribosyltransferase; Western blotting; apoptosis; cell growth; death; flow cytometry; growth retardation; models; myeloma; oxidative stress; reactive oxygen species; synergism; ubiquitin
Abstract:
... Ubiquitin–proteasome pathway (UPP) plays a very important role in the degradation of proteins. Finding novel UPP inhibitors is a promising strategy for treating multiple myeloma (MM).Ub-YFP reporter assays were used as cellular UPP models. MM cell growth, apoptosis and overall death were evaluated with the MTS assay, Annexin V/PI dual-staining flow cytometry, poly (ADP-ribose) polymerase (PARP) cl ...
DOI:
10.1016/j.bbagen.2014.02.006

62. Nutritional risk screening and its clinical significance in hospitalized children

Author:
Cao, Jia,   et al.   ; Peng, Luting; Li, Rong; Chen, Yinhua; Li, Xiaomei; Mo, Baoqing; Li, Xiaonan;     Show all 7 Authors
Source:
Clinical nutrition 2014 v.33 no.3 pp. 432-436
ISSN:
0261-5614
Subject:
children; guidelines; hospitals; nutritional support; risk; risk screening; screening; weight loss
Abstract:
... To analyse nutritional risk in hospitalized children and its relationship with clinical outcomes to provide evidence for improved nutritional management.The investigation involved 1325 consecutively enrolled hospitalized children from Nanjing Children's Hospital. The nutritional risks in the hospitalized children were evaluated using the STRONGkids tool. During hospitalization, the incidence of in ...
DOI:
10.1016/j.clnu.2013.06.009

63. Decreased Pollen Viability and Thicken Pollen Intine in Antisense Silenced Brassica campestris Mutant of BcMF19

Author:
CAO, Jia-shu,   et al.   ; LIU, Jin-long; GAO, Ming-hui; LIU, Ying;     Show all 4 Authors
Source:
Journal of integrative agriculture 2014 v.13 no.5 pp. 954-962
ISSN:
2095-3119
Subject:
viability; in situ hybridization; staining; persimmons; pollen; pollen tubes; microspores; pistil; male fertility; genes; mutants; scanning electron microscopy; statistical analysis; transmission electron microscopy; Brassica rapa subsp. oleifera; prediction
Abstract:
... Brassica campestris male fertility 19 (BcMF19; GenBank accession number GQ902048.1), a gene that is specially expressed in tapetum cells and microspores during anther development in B. campestris ssp. chinensis, which is learned from the previous in situ hybridization study. In the present study, we constructed antisense-silenced plants of BcMF19 using B. campestris ssp. chinensis to validate this ...
DOI:
10.1016/S2095-3119(13)60581-X

64. Air pollution and decreased semen quality: A comparative study of Chongqing urban and rural areas

Author:
Cao, Jia,   et al.   ; Zhou, Niya; Cui, Zhihong; Yang, Sanming; Han, Xue; Chen, Gangcai; Zhou, Ziyuan; Zhai, Chongzhi; Ma, Mingfu; Li, Lianbing; Cai, Min; Li, Yafei; Ao, Lin; Shu, Weiqun; Liu, Jinyi;     Show all 15 Authors
Source:
Environmental pollution 2014 v.187 pp. 145-152
ISSN:
0269-7491
Subject:
air; air pollution; computers; males; nitrogen dioxide; particulates; regression analysis; rural areas; semen; spermatozoa; sulfur dioxide; urban areas; volunteers; China
Abstract:
... To investigate the association and effects of air pollution level on male semen quality in urban and rural areas, this study examines the outdoor concentrations of particulate matter (PM10), sulfur dioxide (SO2), nitrous dioxide (NO2) and semen quality outcomes for 1346 volunteers in both urban and rural areas in Chongqing, China. We found the urban area has a higher pollution level than the rural ...
DOI:
10.1016/j.envpol.2013.12.030

65. Total alkaloids of Tripterygium hypoglaucum (levl.) Hutch inhibits tumor growth both in vitro and in vivo

Author:
Cao, Jia,   et al.   ; Jiang, Xiao; Huang, Xiao-chun; Ao, Lin; Liu, Wen-bin; Han, Fei; Zhang, Dong-yun; Huang, Chuan-shu; Liu, Jin-yi;     Show all 9 Authors
Source:
Journal of ethnopharmacology 2014 v.151 no.1 pp. 292-298
ISSN:
0378-8741
Subject:
Tripterygium; agar; alkaloids; animal models; antineoplastic activity; antineoplastic agents; apoptosis; autoimmune diseases; bioactive compounds; caspase-3; colorectal neoplasms; dose response; flow cytometry; medicinal plants; mice; neoplasm cells; proteins; toxicity; traditional medicine
Abstract:
... Tripterygium hypoglaucum (levl.) Hutch (Celastraceae) (THH) root is a traditional Chinese medicinal herb commonly used for treating autoimmune diseases and cancer. Alkaloid is one of the most bioactive components of THH extract. To evaluate the in vitro and in vivo antitumor properties of the total alkaloids of THH (THHta).THHta was extracted in pilot-scale. HCT116 cells were chose to establish hu ...
DOI:
10.1016/j.jep.2013.10.045

66. Hydrolysis and Photolysis of Herbicide Clomazone in Aqueous Solutions and Natural Water Under Abiotic Conditions

Author:
CAO, Jia,   et al.   ; DIAO, Xiao-ping; HU, Ji-ye;     Show all 3 Authors
Source:
Journal of integrative agriculture 2013 v.12 no.11 pp. 2074-2082
ISSN:
2095-3119
Subject:
aqueous solutions; chlorine; clomazone; dehalogenation; half life; high performance liquid chromatography; hydrogen peroxide; hydrolysis; mass spectrometry; pH; phenol; photolysis; photosensitizing agents; riboflavin; solar radiation; ultraviolet radiation
Abstract:
... The hydrolysis and photolysis of clomazone in aqueous solutions and natural water were assessed under natural and controlled conditions. Kinetics of hydrolysis and photolysis of clomazone were determined by HPLC-DAD. Photoproducts were identified by HPLC-MS. No noticeable hydrolysis occurred in aqueous buffer solutions ((25±2)°C, pH (4.5±0.1), pH (7.4±0.1), pH (9.0±0.1); (50±2)°C, pH (4.5±0.1), pH ...
DOI:
10.1016/S2095-3119(13)60506-7

67. “One-Pot” Reductive Lactone Alkylation Provides a Concise Asymmetric Synthesis of Chiral Isoprenoid Targets

Author:
Cao, Jia,   et al.   ; Perlmutter, Patrick;     Show all 2 Author
Source:
Organic letters 2013 v.15 no.17 pp. 4327-4329
ISSN:
1523-7052
Subject:
Lewis bases; alkylation; chemical structure; cotton; isoprenoids; lactones; odors; sex pheromones; vitamin E
Abstract:
... An efficient method, based on nucleophilic addition to lactones followed by modified in situ Clemmensen reduction, provides a short synthetic route to chiral isoprenoid targets. The efficacy of this method has been exemplified through the synthesis of several targets including the commercial fragrance Rosaphen, the side chain of Zaragozic acid C, the cotton leaf sex pheromone, and the side chains ...
DOI:
10.1021/ol401801g

68. Construction of a New Molecular Barcode for Discriminating Plants and Animals with a Close Genetic Relationship

Author:
CAO, Jia-shu,   et al.   ; HUANG, Li; ZHAO, Xiao-feng; ZHU, Yi-peng; DONG, Heng; XU, Ning-ying;     Show all 6 Authors
Source:
Journal of integrative agriculture 2013 v.12 no.7 pp. 1138-1151
ISSN:
2095-3119
Subject:
DNA barcoding; amplified fragment length polymorphism; animals; barcoding; computer software; cultivars; fluorescence; genes; genetic relationships; genetic variation; new species; plants (botany); species identification; swine breeds; vegetables
Abstract:
... DNA barcodes have been proposed as a shortcut to provide species identification and as a way to accelerate the discovery of new species. A number of candidate gene regions have been suggested as possible barcodes for animals and plants, but for the identification of recently diverged species and/or varieties with only a few genetic differences it has been reported to be problematic in some cases. ...
DOI:
10.1016/S2095-3119(13)60340-8

69. BcMF11, a novel non-coding RNA gene from Brassica campestris, is required for pollen development and male fertility

Author:
Cao, Jia-Shu,   et al.   ; Song, Jiang-Hua; Wang, Cheng-Gang;     Show all 3 Authors
Source:
Plant cell reports 2013 v.32 no.1 pp. 21-30
ISSN:
0721-7714
Subject:
Chinese cabbage; antisense RNA; complementary DNA; transgenic plants; pollen; gametogenesis; pollen tubes; scanning electron microscopy; genes; Brassica rapa subsp. oleifera
Abstract:
... KEY MESSAGE : BcMF11 as a non-coding RNA gene has an essential role in pollen development, and might be useful for regulating the pollen fertility of crops by antisense RNA technology. We previously identified a 828-bp full-length cDNA of BcMF11, a novel pollen-specific non-coding mRNA-like gene from Chinese cabbage (Brassica campestris L. ssp. chinensis Makino). However, little information is kno ...
DOI:
10.1007/s00299-012-1337-6
PubMed:
23064614

70. ANKRD18A as a novel epigenetic regulation gene in lung cancer

Author:
Cao, Jia,   et al.   ; Liu, Wen-bin; Han, Fei; Jiang, Xiao; Yang, Lu-jun; Li, Yong-hong; Liu, Yong; Chen, Hong-qiang; Ao, Lin; Cui, Zhi-hong; Liu, Jin-yi;     Show all 11 Authors
Source:
Biochemical and biophysical research communications 2012 v.429 no.3-4 pp. 180-185
ISSN:
0006-291X
Subject:
DNA methylation; carcinogenesis; early diagnosis; epigenetics; gene expression; gene expression regulation; genes; lung neoplasms; messenger RNA; mortality; neoplasm cells; promoter regions; reverse transcriptase polymerase chain reaction; tissues
Abstract:
... Lung cancer is one of the most common causes of cancer-related mortality worldwide. Effective early diagnosis and targeted therapies for lung cancer to reduce incidence and mortality would benefit from a better understanding of the key molecular changes that occur from normal to malignant tumor cells during lung cancer initiation and development, but these are largely unknown. Previous studies hav ...
DOI:
10.1016/j.bbrc.2012.10.116

71. Novel mutations in the MNX1 gene in two families with Currarino syndrome and variable phenotype

Author:
Cao, Jia,   et al.   ; Markljung, Ellen; Adamovic, Tatjana; Naji, Hussein; Kaiser, Sylvie; Wester, Tomas; Nordenskjöld, Agneta;     Show all 7 Authors
Source:
Gene 2012 v.507 no.1 pp. 50-53
ISSN:
0378-1119
Subject:
penetrance; pancreas; phenotype; frameshift mutation; DNA; boys; congenital abnormalities; missense mutation; genotype; abnormal development; exons
Abstract:
... The Currarino syndrome (CS) consists of a sacral defect, an anorectal malformation and a pre-sacral mass. It manifests as an autosomal dominant congenital malformation in familial settings, with varying penetrance. The disease-causing gene, Motor neuron and pancreas homeobox-1 (MNX1), is known to be mutated in almost all familial cases, but due to the lack of genotype–phenotype correlation, there ...
DOI:
10.1016/j.gene.2012.06.096
PubMed:
22820079

72. A new triterpenoid saponin from Gynostemma pentaphyllum

Author:
Cao, Jia-Qing,   et al.   ; Shi, Lin; Meng, Xian-Jun; Zhao, Yu-Qing;     Show all 4 Authors
Source:
Natural product research 2012 v.26 no.15 pp. 1419-1422
ISSN:
1478-6427
Subject:
Gynostemma pentaphyllum; aerial parts; cytotoxicity; humans; nuclear magnetic resonance spectroscopy; saponins; triterpenoids
Abstract:
... A new dammarane-type triterpene saponin was isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Its structural elucidation was accomplished mainly on the basis of the interpretation of spectroscopic data, such as IR, HR–TOF–MS and NMR. Its cytotoxic activity was evaluated against one human cancer cell line HL-60 using MTT assay. ...
DOI:
10.1080/14786419.2011.599807

73. Ga(ClO₄)₃-catalyzed synthesis of quinoxalines by cycloaddition of α-hydroxyketones and o-phenylenediamines

Author:
Cao, Jia-Jia,   et al.   ; Pan, Fan; Chen, Tang-Ming; Zou, Jian-Ping; Zhang, Wei;     Show all 5 Authors
Source:
Tetrahedron letters 2012 v.53 no.20 pp. 2508-2510
ISSN:
0040-4039
Subject:
chemical reactions; chemical structure; ethanol; quinoxalines; temperature
Abstract:
... A new approach for the synthesis of 2-substituted quinoxalines by Ga(ClO₄)₃-catalyzed cycloaddition of α-hydroxyketones and o-phenylenediamines is introduced. The reaction is catalyzed by 10mol% of Ga(ClO₄)₃ in EtOH at room temperature. It is performed under simple and mild conditions to afford the product in good yield. ...
DOI:
10.1016/j.tetlet.2012.02.113

74. Molecular analysis of DNA repair gene methylation and protein expression during chemical-induced rat lung carcinogenesis

Author:
Cao, Jia,   et al.   ; Liu, Wen-bin; Ao, Lin; Cui, Zhi-hong; Zhou, Zi-yuan; Zhou, Yan-hong; Yuan, Xiao-yan; Xiang, Yun-long; Liu, Jin-yi;     Show all 9 Authors
Source:
Biochemical and biophysical research communications 2011 v.408 no.4 pp. 595-601
ISSN:
0006-291X
Subject:
DNA repair; carcinogenesis; carcinoma; epigenetics; genes; genomic islands; hyperplasia; immunohistochemistry; lung neoplasms; metaplasia; methylation; models; phenotype; polymerase chain reaction; protein synthesis; rats
Abstract:
... A defective ratio between DNA damage and repair may result in the occurrence of a malignant phenotype. Previous studies have found that many genetic alterations in DNA repair genes occur frequently in lung cancer. However, the epigenetic mechanisms underlying this tumorigenesis are not clear. Herein, we have used a chemical-induced rat lung carcinogenesis model to study the evolution of methylatio ...
DOI:
10.1016/j.bbrc.2011.04.067

75. The combined toxicity of dibutyl phthalate and benzo(a)pyrene on the reproductive system of male Sprague Dawley rats in vivo

Author:
Cao, Jia,   et al.   ; Chen, Xuemei; An, Hui; Ao, Lin; Sun, Lei; Liu, Wenbin; Zhou, Ziyuan; Wang, Yingxiong;     Show all 8 Authors
Source:
Journal of hazardous materials 2011 v.186 no.1 pp. 835-841
ISSN:
0304-3894
Subject:
additive effect; adverse effects; benzo(a)pyrene; blood serum; dibutyl phthalate; endocrine-disrupting chemicals; glutathione peroxidase; males; pollutants; rats; rivers; seminiferous epithelium; spermatozoa; superoxide dismutase; testosterone; toxic substances; toxicity; China
Abstract:
... Our previous studies revealed more than 100 pollutants, most of which were endocrine disruptors (EDs) in two Chinese rivers, the Jialing and the Yangtze near Chongqing. Most EDs, such as dibutyl phthalate (DBP) and benzo(a)pyrene (BaP), are known to act individually as reproductive toxicants. However, little is known about the combined toxicity of DBP and BaP. In the current study, male Sprague Da ...
DOI:
10.1016/j.jhazmat.2010.11.078

76. Triterpenoid saponins from Gynostemma pentaphyllum

Author:
Cao, Jia-Qing,   et al.   ; Shi, Lin; Shi, Sheng-Ming; Zhao, Yu-Qing;     Show all 4 Authors
Source:
Journal of Asian natural products research 2011 v.13 no.2 pp. 168-177
ISSN:
1477-2213
Subject:
Gynostemma pentaphyllum; aerial parts; cytotoxicity; nuclear magnetic resonance spectroscopy; triterpenoid saponins
Abstract:
... Four new dammarane-type triterpene saponins, 1–4, were isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Their structural elucidations were accomplished mainly on the basis of spectroscopic methods, such as IR, HR-TOF-MS, and NMR. Compounds 1–4 showed moderate cytotoxic activities against cancer cell lines HL-60, Colon205, and Du145 in vitro. ...
DOI:
10.1080/10286020.2010.547029

77. Seasonal variations of dissolved inorganic nutrients transported to the Linjiang Bay of the Three Gorges Reservoir, China

Author:
Cao, Jia,   et al.   ; Luo, Guyuan; Bu, Faping; Xu, Xiaoyi; Shu, Weiqun;     Show all 5 Authors
Source:
Environmental monitoring and assessment 2011 v.173 no.1-4 pp. 55-64
ISSN:
0167-6369
Subject:
dissolved inorganic nitrogen; dry season; nutrient content; nutrient transport; point source pollution; pollution load; seasonal variation; water quality; wet season; China
Abstract:
... Field surveys were carried out from January 2007 to December 2008 to investigate seasonal variations of dissolved inorganic nitrogen (DIN) and phosphorus (DIP) transported to the Linjiang Bay of the Three Gorges Reservoir, China. The results revealed that both DIN and DIP exhibited large seasonal variability. DIN (dominated by NH₄–N) concentrations were drastically higher in the dry season than th ...
DOI:
10.1007/s10661-010-1370-2
PubMed:
20213063

78. Enhanced cyclic adenosine monophosphate production by Arthrobacter A302 through rational redistribution of metabolic flux

Author:
Cao, Jia-ming,   et al.   ; Chen, Xiao-chun; Song, He; Fang, Ting; Ren, Hua-jing; Bai, Jian-xin; Xiong, Jian; Ouyang, Ping-kai; Ying, Han-jie;     Show all 9 Authors
Source:
Bioresource technology 2010 v.101 no.9 pp. 3159-3163
ISSN:
0960-8524
Subject:
Arthrobacter; citric acid; cyclic AMP; glyceraldehyde 3-phosphate; hypoxanthine; lactic acid; phosphogluconate dehydrogenase; pyruvate kinase; sodium fluoride
Abstract:
... Cyclic adenosine monophosphate (cAMP) was synthesized through the purine salvage synthesis pathway by Arthrobacter A302. Results showed that hypoxanthine was the best of the precursors, and the cAMP concentration reached 4.06g/L. For inhibition of the glycolytic pathway, sodium fluoride was found the optimal effector, which was further studied on cAMP production. With the addition of 0.4g/L of sod ...
DOI:
10.1016/j.biortech.2009.12.081
PubMed:
20064709

79. Determination of antibiotics in sewage from hospitals, nursery and slaughter house, wastewater treatment plant and source water in Chongqing region of Three Gorge Reservoir in China

Author:
Cao, Jia,   et al.   ; Chang, Xiaosong; Meyer, Michael T.; Liu, Xiaoyun; Zhao, Qing; Chen, Hao; Chen, Ji-an; Qiu, Zhiqun; Yang, Lan; Shu, Weiqun;     Show all 10 Authors
Source:
Environmental pollution 2010 v.158 no.5 pp. 1444-1450
ISSN:
0269-7491
Subject:
hospitals; mass spectrometry; norfloxacin; ofloxacin; oxytetracycline; sewage; slaughterhouses; solid phase extraction; tetracycline; trimethoprim; tylosin; wastewater treatment; China
Abstract:
... Sewage samples from 4 hospitals, 1 nursery, 1 slaughter house, 1 wastewater treatment plant and 5 source water samples of Chongqing region of Three Gorge Reservoir were analyzed for macrolide, lincosamide, trimethoprim, fluorouinolone, sulfonamide and tetracycline antibiotics by online solid-phase extraction and liquid chromatography-tandem mass spectrometry. Results showed that the concentration ...
DOI:
10.1016/j.envpol.2009.12.034
PubMed:
20096493

80. Evaluation of eggshell membrane-based bio-adsorbent for solid-phase extraction of linear alkylbenzene sulfonates coupled with high-performance liquid chromatography

Author:
Cao, Jia,   et al.   ; Wang, Weidong; Chen, Bo; Huang, Yuming;     Show all 4 Authors
Source:
Journal of chromatography 2010 v.1217 no.36 pp. 5659-5664
ISSN:
0021-9673
Subject:
adsorbents; egg shell; high performance liquid chromatography; hydrophobic bonding; isoelectric point; models; pH; pollutants; solid phase extraction; sulfonates
Abstract:
... The potential of eggshell membrane (ESM) as a novel solid-phase extraction bio-adsorbent was investigated in the present study. The ESM with a unique structure of intricate lattice network showed a predominant ability to capture linear alkylbenzene sulfonates (LAS) as a model of organic pollutants by the hydrophobic interactions between ESM and LAS molecular at pH very close to the isoelectric poi ...
DOI:
10.1016/j.chroma.2010.07.017

81. Chromosomal aberrations and DNA damage in human populations exposed to the processing of electronics waste

Author:
Cao, Jia,   et al.   ; Liu, Qiang; Li, Ke Qiu; Miao, Xu Hong; Li, Guang; Fan, Fei Yue; Zhao, Yong Cheng;     Show all 7 Authors
Source:
Environmental science and pollution research international 2009 v.16 no.3 pp. 329-338
ISSN:
0944-1344
Subject:
DNA; DNA damage; air; at-risk population; children; chromosome translocation; chromosomes; cytokinesis; developed countries; drinking water; electronic wastes; electronics; environmental quality; epidemiological studies; food chain; genotoxicity; human health; humans; imports; lead; lifestyle; lymphocytes; men; mutation; pollutants; recycling; soil; towns; villages; waste disposal; women; working conditions; Africa; China
Abstract:
... Background, aim, and scope It has been known that the pollutants of electronic wastes (E-wastes) can lead to severe pollution to the environment. It has been reported that about 50% to 80% of E-wastes from developed countries are exported to Asia and Africa. It has become a major global environmental problem to deal with 'E-wastes'. E-waste recycling has remained primitive in Jinghai, China. This ...
DOI:
10.1007/s11356-008-0087-z
PubMed:
19067011

82. Development of two new molecular markers specific to cytoplasmic male sterility in tuber mustard (Brassica juncea var. tumida Tsen et Lee)

Author:
Cao, Jia-shu,   et al.   ; Yu, Xiao-lin; Xiao, Qiu-bin; Chen, Zhu-jun; Hirata, Yutaka;     Show all 5 Authors
Source:
Euphytica 2009 v.166 no.3 pp. 367-378
ISSN:
0014-2336
Subject:
Brassica juncea var. tumida; cytoplasmic male sterility; genetic markers; mitochondrial DNA; restriction fragment length polymorphism; nucleotide sequences; genes; gene expression; messenger RNA; leaves; flowers; maintainer lines
Abstract:
... A novel and stable cytoplasmic male sterility CMS line of tuber mustard has been bred by subsequent backcrosses for 10 years. Two specific markers atpA and orf220 were cloned and partially characterized in our previous study (Zhang et al. 2003). In this study, two new molecular markers, orf256 and orf305/orf324, have been isolated and identified. The orf256 gene size was found to be 825 bp in CMS ...
DOI:
10.1007/s10681-008-9817-z

83. Medium optimization for the production of cyclic adenosine 3',5'-monophosphate by Microbacterium sp. no. 205 using response surface methodology

Author:
Cao, Jia-Ming,   et al.   ; Chen, Xiao-Chun; Bai, Jian-Xin; Li, Zhen-Jiang; Xiong, Jian; Zhang, Lei; Hong, Yuan; Ying, Han-Jie;     Show all 8 Authors
Source:
Bioresource technology 2009 v.100 no.2 pp. 919-924
ISSN:
0960-8524
Subject:
Microbacterium; fermentation; fermenters; models; response surface methodology; soaking
Abstract:
... Response surface methodology was employed to optimize medium composition for the production of cyclic adenosine 3',5'-monophosphate (cAMP) with Microbacterium sp. no. 205. A fractional factorial design (2¹¹⁻⁷) was applied to evaluate the effects of different components in the medium. K₂HPO₄, MgSO₄ and NaF were found to significantly influence on the cAMP production. The steepest ascent method was ...
DOI:
10.1016/j.biortech.2008.07.062
PubMed:
18778935

84. Characterization of a putative pollen-specific arabinogalactan protein gene, BcMF8, from Brassica campestris ssp. chinensis

Author:
Cao, Jia-Shu,   et al.   ; Huang, Li; Zhang, Ai-Hong; Ye, Yi-Qun;     Show all 4 Authors
Source:
Molecular biology reports 2008 v.35 no.4 pp. 631-639
ISSN:
0301-4851
Subject:
Brassica rapa subsp. chinensis; Brassica rapa subsp. oleifera; arabinogalactan proteins; buds; genes; male fertility; males; plant development; pollen; pollination
Abstract:
... The BcMF8 (Brassica campestris male fertility 8) gene, possessing the features of ‘classical’ arabinogalactan protein (AGP) was isolated from Brassica campestris L. ssp. chinensis, Makino syn. B. rapa L. ssp. chinensis. This gene was highly abundant in the fertile flower buds but silenced in the sterile ones of genic male sterile A/B line (‘ZUBajh97-01A/B’) in B. campestris. Expression patterns an ...
DOI:
10.1007/s11033-007-9133-z
PubMed:
17786584

85. Comparative transcript profiling by cDNA-AFLP reveals similar patterns of Avr4/Cf-4- and Avr9/Cf-9-dependent defence gene expression

Author:
CAO, JIA-SHU,   et al.   ; HONG, WEI; XU, YOU-PING; ZHENG, ZHONG; CAI, XIN-ZHONG;     Show all 5 Authors
Source:
Molecular plant pathology 2007 v.8 no.4 pp. 515-527
ISSN:
1464-6722
Subject:
tomatoes; proteins; cell death; seedlings; signal transduction; environmental factors; gene expression; genes; oxidation; photosynthesis; gene expression regulation; hypersensitive response; pathogens; Passalora fulva
Abstract:
... Tomato Cf genes confer resistance to the fungal pathogen Cladosporium fulvum. Although the Cf-4 and Cf-9 proteins are very similar, the Cf-4- and Cf-9-dependent hypersensitive responses (HRs) are distinct in cell death pattern, intensity and sensitivity to environmental conditions. To investigate the mechanism leading to these differences, comparative transcript profiling of Avr4/Cf-4- and Avr9/Cf ...
DOI:
10.1111/j.1364-3703.2007.00412.x
PubMed:
20507518

86. Degradation of environmental endocrine disruptor di-2-ethylhexyl phthalate by a newly discovered bacterium, Microbacterium sp. strain CQ0110Y

Author:
Cao, Jia,   et al.   ; Chen, Ji-an; Li, Xiang; Li, Jun; Qiu, Zhiqun; Zhao, Qing; Xu, Chuan; Shu, Weiqun;     Show all 8 Authors
Source:
Applied microbiology and biotechnology 2007 v.74 no.3 pp. 676-682
ISSN:
0175-7598
Subject:
Microbacterium; activated sludge; bacteria; computer software; endocrine-disrupting chemicals; equations; half life; models; pH; phthalates; ribosomal DNA; temperature; wastewater
Abstract:
... In this study di-2-ethylhexyl phthalate (DEHP)-degradation strain CQ0110Y was isolated from activated sludge. According to the biophysical/biochemical characteristics and analysis of 16S rDNA, the strain was identified as Microbacterium sp. The results of this study showed the optimal pH value and optimal temperature which influenced the degradation rate in wastewater: pH 6.5-7.5, 25-35°C. Kinetic ...
DOI:
10.1007/s00253-006-0700-3
PubMed:
17089119