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- Jiang, Shuai, et al. Show all 6 Authors
- Bioinformatics 2017 v.33 no.17 pp. 2611-2614
- algorithms; binding sites; bioinformatics; chromatin; embryonic stem cells; genes; human cell lines; humans; models; regulatory sequences; transcription (genetics); transcription factors
- ... Motivation: Transcription factor binding sites (TFBSs) are clustered in the human genome, forming the TFBS-clustered regions that regulate gene transcription, which requires dynamic chromatin configurations between promoters and distal regulatory elements. Here, we propose a regulatory model called spatially adjacent TFBS-clustered regions (SATs), in which TFBS-clustered regions are connected by s ...
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