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- Lee, S. C., et al. Show all 6 Authors
- Infection and immunity 2005 v.73 no.3 pp. 1779-1787
- Cryptococcus neoformans; animal models; brain; cerebrospinal fluid; fungi; inflammation; magnetic resonance imaging; meninges; meningoencephalitis; morbidity; mortality; rats
- ... Increased intracranial pressure (ICP) plays an important role in the morbidity and mortality of cryptococcal meningoencephalitis. The microbial and host factors that contribute to the development of increased ICP are poorly understood. We found that phenotypic switch variants of Cryptococcus neoformans (smooth and mucoid) differed in their abilities to promote increased ICP in a rat model of crypt ...
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