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- Li, Zhuoyu, et al. Show all 6 Authors
- BMC biotechnology 2016 v.16 no.1 pp. 65
- Escherichia coli; antineoplastic agents; apoptosis; cytotoxicity; cytotoxins; denaturation; drug delivery systems; neoplasm cells; neoplasms; virulence
- ... BACKGROUND: Targeted therapies for cancer, especially the malignant cancer, are always restricted by the deficiency of tumor-specific drug delivery methods. Subtilase cytotoxic is a virulent cytotoxin, and the subunit A (SubA) of it is able to destroy the structure of glucose-regulated protein 78 (GRP78) to induce cell apoptosis, and to be expected as anti-cancer drugs, however, the ubiquitous rec ...
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