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- Qu, Zhican, et al. Show all 8 Authors
- FEBS letters 2011 v.585 no.19 pp. 3120-3125
- low density lipoprotein; models; prostatic neoplasms
- ... Mesd is a specialized chaperone for Wnt co-receptor low-density lipoprotein receptor-related protein-5 (LRP5) and LRP6, which contain four β-propeller/epidermal growth factor modules, named E1 to E4 from N- to C-terminal, in their extracellular domains. Herein, we demonstrated that recombinant Mesd protein is a general Wnt inhibitor that blocks Wnt/β-catenin signaling induced not only by LRP6 E1-E ...
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