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- Ruiz-Sanz, J., et al. Show all 4 Authors
- Proceedings of the National Academy of Sciences of the United States of America 1994 v.91 no.23 pp. 10943-10946
- Hordeum vulgare; plant proteins; molecular conformation
- ... Possible early events in protein folding may be studied by dissecting proteins into complementary fragments. Two fragments of chymotrypsin inhibitor 2 [CI2-(20-59) and CI2-(60-83)] associate to form a native-like structure in a second-order reaction that combines collision and rearrangement. The transition state of the reaction, analyzed by the protein engineering method on 17 mutants, is remarkab ...
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