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- Yin, Shuang-Hui, et al. Show all 14 Authors
- Veterinary research 2013 v.44 no.1 pp. 259
- Escherichia coli; Foot-and-mouth disease virus; cattle; coat proteins; foot-and-mouth disease; guinea pigs; immune response; immunization; inactivated vaccines; proteolysis; swine; vaccine development; virus-like particle vaccines; virus-like particles
- ... Foot-and-mouth disease virus (FMDV) causes a highly contagious infection in cloven-hoofed animals. The format of FMD virus-like particles (VLP) as a non-replicating particulate vaccine candidate is a promising alternative to conventional inactivated FMDV vaccines. In this study, we explored a prokaryotic system to express and assemble the FMD VLP and validated the potential of VLP as an FMDV vacci ...
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