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cell biology; cryo-electron microscopy; data collection
Abstract:
... This review summarizes the current state of methods and results achievable by cryo-electron microscopy (cryo-EM) imaging for molecular, cell, and structural biologists who wish to understand what is required and how it might help to address their research questions. It covers some of the main issues in sample preparation, microscopes and data collection, image processing, three-dimensional (3D) re ...
... This essay contributes to work in media geography by bringing the geography of nostalgia into conversation with media nostalgia. Through an analysis of Amazon’s The Marvelous Mrs. Maisel’s text, intertextual discourses, location production, and tourism, I demonstrate how TV works to produce nostalgic attachments to places past, intervening materially into the present/future. Specifically, I argue ...
climate change; local government; national surveys; Australia
Abstract:
... Local governments are at the forefront of climate change adaptation planning. Although there is significant research on adaptation planning processes, there is scant empirical evidence of how local governments are completing the adaptation planning cycle by monitoring or evaluating their efforts. This leads to a fundamental lack of understanding about what actions work, in which contexts, and why? ...
... Diabetes mellitus is a chronic metabolic disorder and is associated with depleted vitamin C status. The underlying aetiologies and pathogeneses responsible for this association are poorly understood. This retrospective study explored the vitamin C status of 136 adult outpatients with types 1 and 2 diabetes mellitus (T1DM/T2DM), with a focus on indices of renal function and metabolic health, includ ...
Chlorella vulgaris; bioprocessing; dewatering; energy use and consumption; microalgae; microfluidic technology
Abstract:
... The aim of this study was to explore an alternative mode of operation for inertial focusing systems and determine the maximum inlet volume fractions at which device performance can be maintained (i.e. cell retention efficiency remains high, here defined as >95%). Microalgae dewatering was selected as a demonstrator application, specifically using Chlorella. A spiral inertial focusing device was ch ...
data collection; hydrologic models; model validation; motivation; runoff; summer; watersheds; United Kingdom
Abstract:
... The choice of hydrological model, especially on the catchment scale, is never an easy one. This of course is dependent on the problem under consideration and the end user requirement. The continued development in data acquisition and its availability has taken us in the direction of more complex model development and application. Yet, it remains critical to identify a model that is not only parsim ...
... Vitamin A is a fat-soluble micronutrient necessary for the growth of healthy skin and hair. However, both too little and too much vitamin A has deleterious effects. Retinoic acid and retinal are the main active metabolites of vitamin A. Retinoic acid dose-dependently regulates hair follicle stem cells, influencing the functioning of the hair cycle, wound healing, and melanocyte stem cells. Retinoi ...
Human betaherpesvirus 5; agonists; chemokine CX3CL1; mitogen-activated protein kinase; mitogens; physiology; transcription factor NF-kappa B; trophoblast
Abstract:
... Human cytomegalovirus (HCMV) encodes four homologs of G protein coupled receptors (vGPCRs), of which two, designated UL33 and US28, signal constitutively. UL33 and US28 are also conserved with chemokine receptors: US28 binds numerous chemokine classes, including the membrane bound chemokine, fractalkine; whereas UL33 remains an orphan receptor. There is emerging data that UL33 and US28 each contri ...
... Reluctance to eat new foods, known as food neophobia, is well researched in children but not adults. Two studies were carried out to understand the emotional, sensory, and cognitive factors associated with food neophobia in an adult sample, and to propose a preliminary explanation of the decision to taste a novel food named the SEA model (Sensory, Emotional, cognitive Association model). Participa ...
air pollution; child development; ecosystems; environment; gender; green infrastructure; heat; humans; mental health; people; physical activity; recreation; social cohesion; society; urbanization; wildlife; Nepal
Abstract:
... Exposure to urban greenspaces promotes a variety of mental health benefits. However, much of the evidence for these benefits is biased towards high-income countries. In contrast, urban areas in low-income settings that have the highest rates of urbanisation remain understudied. Given the increasing burden of mental ill-health associated with urbanisation in low- and middle-income countries (LMICs) ...
... In the Half-Earth vision, conservationists, scientists, and policymakers work together with local communities without compromising the interests of wildlife and ecosystems. The vision requires decolonizing nonhuman species through marshaling ecocentric philosophy, animal sentience science, and, crucially, local communities' support. While the studies of community attitudes to wildlife are accumula ...
National Oceanic and Atmospheric Administration; meteorology; satellites; surface water temperature; Great Barrier Reef
Abstract:
... Sea surface temperature (SST) products that can resolve fine scale features, such as sub-mesoscale eddies, ocean fronts and coastal upwelling, are increasingly in demand. In response to user requirements for gap-free, highest spatial resolution, best quality and highest accuracy SST data, the Australian Bureau of Meteorology (BoM) produces operational, real-time Multi-sensor SST level 3 products b ...
behavior change; conspecificity; environmental enrichment; service dogs; working conditions
Abstract:
... Environmental enrichment (EE) can be used to enhance the environment of various animals. The aim of this pilot study was to determine the effects of seven EE activities (Bonding, Bubble machine, Conspecific play, Interactive toy, Playhouse, Stuffed food toy and Tug play) on dog behaviour, pre- and post-EE for dogs housed in an office environment during training as part of an assistance dog trainin ...
... Mice have emerged as one of the most popular and valuable model organisms in the research of human biology. This is due to their genetic and physiological similarity to humans, short generation times, availability of genetically homologous inbred strains, and relatively easy laboratory maintenance. Therefore, following the release of the initial human reference genome, the generation of the mouse ...
anaerobic digestion; homogenization; methane production; particle size; principal component analysis; renewable energy sources; solubilization; water holding capacity
Abstract:
... Three successive mechanical pretreatments were applied at lab-scale in order to mimic the main functions of industrial mechanical pretreatments used for feedstock preparation in anaerobic digestion: particle size reduction (shredding), homogenization (mixing) and fiber alteration (blending). In parallel, full-scale mechanical devices have been investigated (two hammer mills and one chain mill). A ...
... We review the development of field guides (in a broad sense) to British spiders from 1678 to the present day, and note features which made, or make, them more or less suitable for use in the field. The review concludes by exploring the future of paper field guides to this group of organisms in the era of electronic devices. ...
compliance; cost effectiveness; environmental performance; markets; China
Abstract:
... Environmental self-regulation (ESR) is an increasingly important instrument to solve environmental problems. Although ESR is linked to improved firms' environmental performance, it is unclear whether ESR benefits firms’ long-term survival. We use environmental certifications, an externally certified form of ESR, and operation data of Chinese manufacturing firms from 1999 to 2013 to examine the imp ...
... The fungal pathogen Lecanicillium fungicola causes dry bubble disease in Agaricus bisporus cultivation and affected mushrooms significantly reduce the yield and revenue for mushroom growers. Biocontrol agents may represent an alternative and more environmentally friendly treatment option to help control dry bubble on mushroom farms. Serenade ® is a commercially available biocontrol product used fo ...
... The application of animal manure as a source of plant nutrients requires the determination of the amount and pattern of nutrient mineralization from manure. A laboratory incubation study was conducted to investigate the influence of lignite amendment and lignite type on carbon (C) and nitrogen (N) mineralization in raw (feedstock) and composted cattle manure following application to soil at 30 and ...
ecology; environment; environmental impact; macroinvertebrates; rivers; water; England
Abstract:
... Flow–ecology relationships within river systems are an important area of ongoing investigation, because of potential applications such as understanding the ecological impact of flow alteration at modified sites. This study analyses relationships between flow characteristics and benthic macroinvertebrates from 18 streams of similar size and typology within Northern England, to develop quantitative ...
aggregate fruits; avocados; cooling; exports; fruit quality; horticulture; risk; shelf life; storage temperature; New Zealand
Abstract:
... ‘Hass’ avocado fruit are usually packed the day after harvest and then immediately cooled and held no more than a few days before export. This procedure is considered to maximise the storage life and quality of the fruit. However, for packhouse logistics, there are times when it may be advantageous to aggregate fruit over a period of days before packing. It is hypothesised that the time at which f ...
ammonium; aquatic ecosystems; arable soils; biofilm; chlorophyll; land cover; nonpoint source pollution; reactive phosphorus; river water; rivers; sediments; sewage; sewage effluent; sewage treatment; summer; wastewater treatment; water quality; watersheds; Scotland
Abstract:
... Discharge of treated sewage effluent to rivers can degrade aquatic ecosystem quality, interacting with multiple stressors in the wider catchment. In predominantly rural catchments, the river reach influence of point source effluents is unknown relative to complex background pressures. We examined water column, sediment and biofilm biogeochemical water quality parameters along river transects (200 ...
... Consumer dietary awareness drives a need for minimally processed foods with quality sensory and nutritional attributes and extended shelf life. Sous vide cooking techniques are a viable technology for meeting these consumer demands. Sous vide is the process of cooking vacuum-sealed foods in plastic pouches at low temperatures, generally 55–60 °C, for an extended period under strictly controlled co ...
climate; climate models; cost estimates; cyst nematodes; plant pathology; population growth; potatoes; United Kingdom
Abstract:
... Potato cyst nematodes (PCN) are economically important pests of potato plants worldwide that can result in yield losses exceeding 80%, with an estimated cost of £50 million annually in the United Kingdom alone. The life cycle of PCN, and in particular the hatching of eggs and development and survival of juveniles, is sensitive to temperatures in the soil. Despite this fact, relatively little is kn ...
analytical chemistry; caffeine; dissociation; electrospray ionization mass spectrometry; metabolites; metabolomics; nitrogen; protein subunits
Abstract:
... The structural annotation of isomeric metabolites remains a key challenge in untargeted electrospray ionization/high-resolution mass spectrometry (ESI/HRMS) metabolomic analysis. Many metabolites are polyfunctional compounds that may form protomers in electrospray ionization sources and therefore yield multiple peaks in ion mobility spectra. Protomer formation is strongly structure-specific. Here, ...
chemical species; color; colorimetry; methamphetamines; nanogold; nucleotide aptamers; signal transduction; thermodynamics
Abstract:
... DNA aptamers have emerged as promising probes for challenging analytes that cannot be easily detected by conventional probes, including small-molecule targets. Among the different signal transduction approaches, gold nanoparticle (AuNP) aggregation assays have been widely used to generate a colorimetric response from aptamer–target interactions. This sensor design relies on the competition between ...
... Bambara groundnut (BGN) is termed a complete food due to its nutritional composition and has been researched often for its nutritional constituents. Malting BGN seeds have shown improved nutritional and functional characteristics, which can be used to produce an amylase-rich product as a functional ingredient for food and beverage production in homes and industries. The aim of this study was to in ...
... In the pursuit of highly active specialized metabolites from endemic plants, Centaurea papposa (Coss.) Greuter, an endemic plant in Algeria and Tunisia, was investigated and afforded eleven sesquiterpene lactones (1-11). Cytotoxic evaluation of these compounds using the in vitro MTT assay on three human cancerous cell lines (HeLa, SK-MEL-28 and HepG2), revealed that isolates 4, 8 and 9 (IC₅₀ ≤ 10 ...
... Bacterial drug-efflux transporters act synergistically with diffusion barriers of cellular membranes and other resistance mechanisms to protect cells from antibiotics and toxic metabolites. Their critical roles in clinical antibiotic and multidrug resistance are well established. In addition, a large body of evidence has been accumulated in support of their important contributions to bacterial gro ...
... This article describes the preparation of hierarchical microsieves via float-casting using raspberry particles. The raspberry particles consist of a larger spherical particle (the core) and smaller particles (satellites) that are attached on the surface of the core and were connected to the core via a surface reaction of isocyanate and amino groups. The raspberry particles were spread onto a water ...
... Household Consumption Expenditure Survey (HCES) data are increasingly used to inform nutrition policy around the world, most prominently for food fortification programs. However, they risk providing incorrect and gender-biased estimates of dietary intakes. We use both 7-day HCES and 24-hour dietary recall (24HR) data on all members of 5604 households in rural Bangladesh to disentangle the two main ...
... BACKGROUND: In recent years there has been an increased focus on the role of large herbivores in ecosystem restoration and climate change mitigation. There are multiple processes by which large herbivores could potentially influence climate feedback and forcing effects, but the evidence has not yet been synthesised in a systematic and accessible format. Grazing, browsing, trampling, defecation, an ...
... Plastic pollution is a pervasive and escalating global environmental problem, named among the most serious environmental issues globally, after climate change. A large percentage of the global plastic waste leakage is estimated to come from Asia, and most of this is from food and drink packaging. As a major user of single-use packaging, the food and beverage sector plays an important role in addre ...
cardiovascular diseases; fetus; high density lipoprotein cholesterol; inflammation; pre-eclampsia; pregnancy; premature birth; risk
Abstract:
... High density lipoproteins (HDL) were first linked to cardiovascular disease (CVD) over 30 years ago when an inverse relationship was shown between CVD and HDL-cholesterol levels. It is now apparent that HDL composition and function, not cholesterol levels, are the pertinent measurements describing HDL's role in various disease processes, especially those with subclinical or overt inflammation.Preg ...
... Composted swine (Sus domesticus) lagoon solids may provide a nutrient rich alternative to peatmoss (Sphagnum sp.) in a transplant substrate while dispersing the concentrated nutrients of this waste product in a cost effective, environmentally conscientious manner. The objective of this study was to evaluate the physical and chemical characteristics of swine lagoon solids composted with peanut (Ara ...
... Complex molecules produced by plants have provided us with a range of medicines, flavour and fragrance compounds and pesticides. However, there are challenges associated with accessing these in an economically viable manner, including low natural abundance and the requirement for complex multi-step synthetic strategies. Chemoenzymatic approaches provide a valuable alternative strategy by combining ...
adults; hooves; horses; photogrammetry; scanners; statistical models; veterinary medicine
Abstract:
... Equine hoof conformation is integral to equine performance and soundness. Consequently, it is a major area of interest within the field of equine health. Researchers have measured several hoof shape parameters to study the hoof conformation. Proximal hoof circumference (PHC) is a primary hoof shape parameter, and its assessment may help to recognize the early stages of the development of changes i ...
health promotion; health services; obesity; stakeholders; telemedicine; weight loss
Abstract:
... Design research methods, including user‐centered design, human‐centered design, and design thinking, are iterative processes and frameworks that engage stakeholders to inform the design of initiatives, programs, or research interventions. Design research methods are not yet widely applied in healthcare. To date, there is a limited understanding of how design research methodologies can be applied t ...
employment; food industry; food production; food safety; human health; medicine; research; risk; shelf life; toxicity; traditional foods
Abstract:
... Nanotechnology involves developing, characterising, and applying structures ranging in size from 1 to 100 nm. As a key advanced technology, it has contributed to a substantial impact across engineering, medicine, agriculture and food. With regards to their application in food, nanomaterials posses the ability to lead the quantitative and qualitative development of high-quality, healthier, and safe ...
... Elevated platforms are a suitable possibility to enrich the environment of broiler chicken and, thus, improving their welfare. Early detection of health problems additionally contributes to an improved welfare of chickens and, at the same time, helps the farmer to optimize production efficiency. A prototype combined elevated platforms with weighing beams and an algorithm was developed to estimate ...
... Chicken eggshell membrane (ESM) is a highly insoluble structure that is greatly stabilized by extensive desmosine, isodesmosine, and disulfide cross-linkages. The ESM possesses numerous biological functions including anti-microbial, anti-inflammatory, anti-wrinkle, and antioxidant activities. The ESM is mainly proteinaceous; proteomics and bioinformatics analysis of ESM has identified > 500 protei ...
... Timely and accurate forecasts of dengue cases are of great importance for guiding disease prevention strategies, but still face challenges from (1) time-effectiveness due to time-consuming satellite data downloading and processing, (2) weak spatial representation capability due to data dependence on administrative unit-based statistics or weather station-based observations, and (3) stagnant accura ...
... BACKGROUND: There is a lack of literature concerning dairy farmers' use of veterinary services and how satisfied they are with them. This study aimed to fill this gap for seasonal calving UK herds, with a focus on fertility, and included farmer perceived barriers to veterinary involvement. METHODS: A cross‐sectional questionnaire (convenience sample), with 166 useable responses. RESULTS: Opportuni ...
dialysis; hypothyroidism; immunoassays; research; thyroxine; veterinary medicine
Abstract:
... Measurement of free T4 by analogue immunoassay (fT4a) is popular but its ability to differentiate hypothyroidism from non-thyroidal illness (NTI) is unclear. The aims were to assess fT4a concentrations in dogs with NTI and to explore diagnostic agreement with total T4 and free T4 measured by equilibrium dialysis (fT4d). fT4a was measured in dogs classified with mild, moderate and severe NTI. Total ...
COVID-19 infection; World Health Organization; childhood; outreach; vaccines; Australia
Abstract:
... In 2017 the World Health Organization’s Tailoring Immunization Programmes guide (TIP) was used to identify pockets of low immunization coverage in Australia. The regional centre of Maitland had high numbers and rates of children who were overdue for scheduled vaccinations (2016, n = 344, 37.7%). Families were not opposed to immunization but had conflicting priorities or experienced service access ...
... Floating treatment wetlands are an innovative wetland design to passively improve water quality and remove pollutants from reservoirs with limited infrastructure modification or construction as compared to traditional treatment wetlands. However, design recommendations remain limited. Therefore, the objectives of this study were: 1. Determine nitrate-N removal rates in two floating treatment wetla ...
... Offal tissues carry a lower market value compared to skeletal meats in some global markets. The inclusion of offal in any meat product in the EU and UK must be declared on the label. While many technologies have been applied to the challenge of determining adulteration with offal in meat products, no single method has been recognised and validated as a reliable test to support legislative requirem ...
... Clinical studies have revealed that the ABCB4 gene encodes the phospholipid transporter on the canalicular membrane of hepatocytes, and its mutations and variants are the genetic basis of low phospholipid-associated cholelithiasis (LPAC), a rare type of gallstone disease caused by a single-gene mutation or variation. The main features of LPAC include a reduction or deficiency of phospholipids in b ...
adults; appetite; computer software; cross-over studies; energy intake; food records; laboratory experimentation; social facilitation
Abstract:
... People eat more when they eat a meal with familiar others than they do when eating alone. However, it is unknown whether eating socially impacts intake over the longer-term. The aim of Study 1 was to examine whether socially facilitated intake is sustained across all meals and across three consecutive days. The aim of Study 2 was to examine whether increased intake during a social meal taken in th ...
... Many sub-Saharan African countries implementing agricultural input subsidies programmes (AISP) concentrate on fertilizers and staple food crops which may have little or no effect on consumption of diverse nutrient dense non-staple foods. The programme in Malawi – the Farm Input Subsidy Programme (FISP) – includes legume seeds, but little research has been undertaken to evaluate the effects of this ...
... Overworking and overloading of donkeys may cause fatigue. The experiment aims to determine the effects of epicatechin-(4β-8)-catechin (EEC) on some fatigue biomarkers in packed donkeys during the dry season. 10 jacks, aged between four and five years were used for the study. Five were given EEC in feed seven days before packing (test), while another five were given feed only (control). Blood sampl ...
Lycaon pictus; Oryx; data collection; dogs; ecosystems; environmental impact; habitat connectivity; human-wildlife relations; permeability; population dynamics; wildlife; Kenya
Abstract:
... Wildlife fences are often considered an important tool in conservation. Fences are used in attempts to prevent human–wildlife conflict and reduce poaching, despite known negative impacts on landscape connectivity and animal movement patterns. Such impacts are likely to be particularly important for wide-ranging species, such as the African wild dog Lycaon pictus, which requires large areas of cont ...
United States Environmental Protection Agency; ambient water quality; copper; databases; humans; hydrology; income; lead; mercury; Southeastern United States
Abstract:
... Water is an essential human resource tied to many social and environmental needs and values. Although water has been a focal point of many environmental justice studies, ambient water quality (i.e. water quality before the tap) has been overlooked. This oversight has resulted in only a partial understanding of how water quality may correlate with communities facing environmental justice issues. We ...
... Methyl α(and β)-D-3,4-anhydro-tagatofuranosides are important synthetic building blocks as they undergo regioselective ring-opening to afford exclusively products with the D-fructo configuration. Previous attempts to prepare these compounds from the corresponding methyl D-fructofuranosides under standard Mitsunobu conditions have led to an undesired 9:1 mixture of tagato and psico oxiranes. We now ...
... While recording fish habitat use by electronic sensors, biologgers can also be viewed as autonomous environmental monitoring systems with the organism as a vehicle. This dual perspective has provided novel results from marine ecosystems, but has not been applied to freshwater ecosystems. To understand limitations in fresh water, we evaluated miniature depth and temperature recorders as aquatic mon ...
... Ecological restoration is a promising way to improve ecological function, habitat connectivity, and esthetic values for recreation. However, effective restoration practices for arid environments remain elusive. To help fill this knowledge gap, we tested ripping soils, seed mixtures, including adding native seed bank topsoils, and seeding timing on permanently closed trails at sites in the Sonoran ...
... Dipolar aprotic and ethereal solvents comprise just over 40% of all organic solvents utilized in synthetic organic, medicinal, and process chemistry. Unfortunately, many of the common “go-to” solvents are considered to be “less-preferable” for a number of environmental, health, and safety (EHS) reasons such as toxicity, mutagenicity, carcinogenicity, or for practical handling reasons such as flamm ...
energy efficiency; environmental impact; insulating materials; markets; pollution; wastes
Abstract:
... As plastic pollution is eroding our ecological environment at an alarming rate around the world, tracking the origins is a necessity for putting forward effective measures to prevent it. The building industry, as an important sector consuming plastic products and producing plastic wastes, is increasing application of thermal insulations to improve energy efficiency. However, most insulation materi ...
... Any uncertainty in determining numbers of microplastics in the environment may be a barrier to assessing their impact and may stem from various aspects of methodologies used to quantify them. We undertook a comparison of approaches to quantify and characterize microplastics in 4 personal care products. The aim was not only to determine how many particles were present but to assess any differences ...
... Acylcarnitines are essential diagnostic markers for complex diseases and fatty acid metabolism disorders, and play an important role in cardiovascular diseases. Herein, a HILIC-MS/MS method was developed and validated for the rapid quantitation of the acylcarnitines C2, C3, C4, C5, C6, C8, C10, C12, C14, C16, C18, C18:1 and C18:2 in human serum. RPLC and HILIC modes were tested, and HILIC was sele ...
case studies; disaster preparedness; model validation; models; rivers
Abstract:
... Flood inundation forecast maps provide an essential tool to disaster management teams for planning and preparation ahead of a flood event in order to mitigate the impacts of flooding on the community. Evaluating the accuracy of forecast flood maps is essential for model development and improving future flood predictions. Conventional, quantitative binary verification measures typically provide a d ...
... Inspired by light-induced processes in nature to mimic the primary events in the photosynthetic reaction centers, novel functional materials combine electron donors and acceptors, i.e., (metallo)porphyrins (ZnP) and fullerenes (C₆₀), respectively, with emerging materials, i.e., nanographenes. We utilized hexa-peri-hexabenzocoronene (HBC) due to its versatility regarding functionalization and physi ...
adiposity; alcohols; body mass index; energy; grain consumption; lifestyle; obesity; physical activity; pregnancy; risk; sociodemographic characteristics; surveys; weight gain
Abstract:
... Pre-pregnancy, pregnancy and postpartum are critical life stages associated with higher weight gain and obesity risk. Among these women, the sociodemographic groups at highest risk for suboptimal lifestyle behaviours and core lifestyle components associated with excess adiposity are unclear. This study sought to identify subgroups of women meeting diet/physical activity (PA) recommendations in rel ...
cost effectiveness; disease prevention; gross domestic product; health care costs; landscapes; vaccination; vaccines; Africa; Middle East
Abstract:
... Vaccination is a cost-effective disease prevention measure. Sustainable financing is critical to successful implementation of vaccination programs. Countries in the Middle East and Africa (MEA) have vaccination programs that remain highly vulnerable to budget limitations. The objective of this study was to understand the current vaccine financing landscape in MEA; to assess the availability and va ...
United Nations Educational, Scientific and Cultural Organization; air pollution; air quality; biomass; feces; geochemistry; ovens; particulates; people; wood
Abstract:
... The use of wood, dung and other biomass fuels can be traced back to early prehistory. While the study of prehistoric fuel use and its environmental impacts is well established, there has been little investigation of the health impacts this would have had, particularly in the Neolithic period, when people went from living in relatively small groups, to living in dense settlements. The UNESCO World ...
... Ophiobolin A is a secondary phytotoxic metabolite produced by some pathogenic fungal species responsible for severe plant diseases, considered to play a role in disease development and symptom appearance. Herein we investigated whether the phytotoxic activities of ophiobolin A against weed species could be improved by nanoencapsulation. Given the rapid natural degradation of the compound, it was h ...
... With a focus on five sites in an impaired, densely populated area in the New Orleans area, we investigated the temporal and spatial variability of standard FIB and a marker of human-associated pollution (Bacteroides HF183). With all sites combined, only a weak positive correlation (r = 0.345; p = 0.001) was observed between E. coli and HF183. Also, specific conductivity (r = - 0.374; p < 0.0001) a ...
DNA methylation; ammonia; biomarkers; cancer therapy; carcinogenesis; colorectal neoplasms; databases; drug therapy; drugs; gene expression; glycolysis; metastasis; mice; models; mortality; mutation; patients; proteomics; radiotherapy; xenotransplantation
Abstract:
... Surgery, radiation therapy (RT), and chemotherapy are commonly used treatment modalities for CRC management. The locally advanced CRC is managed with preoperative RT or in combination of chemoradiotherapy whereas palliative RT is recommended for metastatic CRC patients to enhance overall survival and reduce distressing symptoms. There are many biomarkers established based on tumour staging, gradin ...
calcium; phosphorus; quartz; sand; sorbents; sorption; tap water; wastewater treatment; water
Abstract:
... (1) Phosphorus (P) removal has proven difficult in decentralized wastewater treatment systems, and external filters installed with a highly P sorbent material have been proposed to improve the P removal. In particular, calcium (Ca) rich materials have shown promising results. (2) Eight materials (five calcareous materials, one quartz sand, and two Sol–Gel coated calcareous materials) were tested i ...
... Superbase ionic liquids (ILs) with a trihexyltetradecylphosphonium cation and a benzimidazolide ([P₆₆₆₁₄][Benzim]) or tetrazolide ([P₆₆₆₁₄][Tetz]) anion were investigated in a dual-IL system allowing the selective capture and separation of CO₂ and SO₂, respectively, under realistic gas concentrations. The results show that [P₆₆₆₁₄][Tetz] is capable of efficiently capturing SO₂ in preference to CO₂ ...
Bacillariophyceae; Copepoda; Miozoa; aquatic food webs; autumn; dissolved phosphorus; global change; microalgae; phytoplankton; North Sea
Abstract:
... Phytoplanktonic organisms are particularly sensitive to environmental change, and, as they represent a direct link between abiotic and biotic compartments within the marine food web, changes in the functional structure of phytoplankton communities can result in profound impacts on ecosystem functioning. Using a trait‐based approach, we examined changes in the functional structure of the southern N ...
data collection; decision making; ecosystem services; ecosystems; environmental management; evolution; flood control; outdoor recreation; risk assessment process; China; South East Asia
Abstract:
... Natural ecosystems are fundamental to local water cycles and the water ecosystem services that humans enjoy, such as water provision, outdoor recreation, and flood protection. However, integrating ecosystem services into water resources management requires that they be acknowledged, quantified, and communicated to decision-makers. We present an indicator framework that incorporates the supply of, ...
... Urinary schistosomiasis (US), also known as bilharziasis is a waterborne parasitic infection most common in rural areas of developing countries. The infection is associated with haematuria but little or nothing is known about its association with other urinary parameters, induction of Nitric Oxide (NO) and IgE production around the Bamendjing Dam an area highly suspected of Schistosoma haematobium ...
... As consumer needs change, innovative food processing techniques are being developed that have minimal impact on food quality and ensure its microbiological safety. Sous vide (SV) is an emerging technology of cooking foods in vacuum pouches at specific temperatures, which results in even heat distribution. Presented here is an overview of the current state of the art in the application of SV techni ...
global change; issues and policy; momentum; Europe
Abstract:
... The notion that pathways can be identified and followed towards more sustainable futures has become an increasingly prevalent idea across the science and policy of global environmental change. Focusing on the debate within literatures on socio-technical systems, we find that pathways are often tied to the concept of scaling up such that they are dependent on trajectories which extend from the geog ...
... Mollusks, especially bivalves, exhibit a great diversity of sex determining mechanisms, including both genetic and environmental sex determination. Some bivalve species can be gonochoristic (separate sexes), while others are hermaphroditic (sequential or simultaneous). Several models have been proposed for specific bivalve species, utilizing information gained from gene expression data, as well as ...
Mediterranean diet; Western diets; bioelectrical impedance; cachexia; cross-over studies; dielectric spectroscopy; employment; lean body mass; rheumatoid arthritis
Abstract:
... Rheumatoid Arthritis (RA) is an autoimmune disease affecting peripheral joints. Chronic activation of inflammatory pathways results in decreased function and the development of comorbidities, such as loss of lean mass while retaining total body mass. The objective of this report was to assess whether dietary manipulation affects body composition in patients with RA as a secondary outcome. Fifty pa ...
... The oral microbiota can contribute to the regulation of blood pressure by increasing the availability of nitric oxide through the reduction of nitrate to nitrite, which can be converted into nitric oxide in the stomach and then enter the circulation. It is unclear if the composition of the oral microbiota is different between women who do and do not develop preeclampsia. This study aimed to compar ...
... Combining thermopreference (Tₚ) and CO₂-gated heat-seeking assays, we studied the thermal preferendum and response to thermal cues in three Culex mosquito species exhibiting differences in native habitat and host preference (e.g., biting cold and/or warm-blooded animals). Results show that these species differ in both Tₚ and heat-seeking behavior. In particular, we found that Culex territans, whic ...
... Research suggests that the COVID-19 pandemic is negatively impacting mental health, with rates of eating disorder referrals in particular rising steeply during the pandemic. This study aimed to examine 8-month changes in body image and disordered eating during the COVID-19 pandemic, and explore whether any changes were moderated by gender, age, or eating disorder history. This study used a longitu ...
adults; census data; health policy; health services; influenza; medical records; monitoring; patients; resource allocation; vaccines; Pennsylvania
Abstract:
... Numerous studies in the U.S. have made estimates of the RSV burden among adults that vary widely due to differences in methodology, reliance on influenza surveillance, which does not adequately capture all RSV clinical symptoms, and lack of diagnostic methods to identify RSV when viral loads are low. Nevertheless, accurate burden estimates can inform healthcare planning, resource allocation and po ...
... Used in Asian countries, including China, Japan, and Thailand, Houttuynia cordata Thumb (H. cordata; Saururaceae, HC) is a traditional herbal medicine that possesses favorable antiviral properties. As a potent folk therapy used to treat pulmonary infections, further research is required to fully elucidate the mechanisms of its pharmacological activities and explore its therapeutic potential for tr ...
... This paper presents a tiered assessment approach that enabled identification, triage, interrogation and confirmation of significantly contaminated areas of an urbanised West Australian estuary. The spatial distribution of organochlorine pesticides (OCPs), polycyclic aromatic hydrocarbons (PAHs) and bioavailable metals was determined in surficial sediments of the Swan-Canning Estuary through broad- ...
... BACKGROUND: Pesticide residue data for pollen and nectar are valuable for characterizing realistic exposure of pollinators, e.g. from agricultural crops, flowering margins. Interpretation of residues relies on comparing exposure with toxicity and the Hazard Quotient (HQ) is widely utilized. However, the HQ (threshold of concern 50) was only validated for foliar sprays, based on application rate as ...
... In the context of veterinary education, simulators are devices or sets of conditions aiming to imitate real patients and enable students to practice skills without the need for live animal use. Simulator use in veterinary education has increased significantly in recent years, allowing consistent practical teaching without reliance on clinical cases. This review examines the available literature re ...
... Resveratrol is a known anti-oxidant and anti-cancer bioactive. The low bioavailability and poor water solubility of resveratrol is a major barrier that restricts its usage in food applications. To overcome these problems, the study presents micro and nano encapsulation of resveratrol in casein micelles extracted from Himalayan cheese (Churpi). Resveratrol loaded casein microparticles (CS-rm) were ...
... Mechanisms linked to demographic, biogeographic, and food‐web processes thought to underpin community stability could be affected by habitat size, but the effects of habitat size on community stability remain relatively unknown. We investigated whether those habitat‐size‐dependent properties influenced community instability and vulnerability to perturbations caused by disturbance. This is particul ...
... All living cells are surrounded by lipidic membranes that separate metabolic and macromolecular biosynthetic processes from external environments. Biological membranes vary dramatically in their composition and structures and are optimized by mega-annum of evolution to effectively carry out diverse biological functions including energy production, biosynthetic reactions, signaling, uptake of nutri ...
... Spatially explicit information on soil variability is relevant for agronomic decisions; however, such information is limited in the northern Guinea savanna (NGS) agroecological zone of Nigeria. This study was conducted to delineate soil nutrient management zones (MZs), based on spatial variability of soils in the smallholder maize-based farming system within the NGS. Two hundred and eighty-nine so ...
amination; green chemistry; mechanochemistry; solvents; transaminases
Abstract:
... Mechanochemical reactions have emerged in recent years as a green synthetic method because reactions can be performed more rapidly and using less solvent than traditional synthetic approaches. To date, very few mechanoenzymatic reactions have been described. For the first time, transaminases, which are widely used for the amination of aldehydes and ketones, have been used here under mechanoenzymat ...
... Adequate infant and young child feeding during the first 1000 days of life is very essential to improve child health, survival, growth, and development through minimum dietary diversity (MDD). Hence, this study aimed to assess MDD and its multi-level factors among infants and young children aged 6–23 months in Ethiopia. Ethiopian Demographic and Health Survey (EDHS-2016) data was used to identify ...
... Degradation of autophagosomal cargo requires the tethering and fusion of autophagosomes with lysosomes that is mediated by the scaffolding protein autophagy related 14 (ATG14). Here, we report that phosphatidylinositol 4-kinase 2A (PI4K2A) generates a pool of phosphatidylinositol 4-phosphate (PI4P) that facilitates the recruitment of ATG14 to mature autophagosomes. We also show that PI4K2A binds t ...
Helen Karasali, et al. ; George Pavlidis; Ioanna Zotou; Anna Marousopoulou; Georgios Bariamis; Vassilios A. Tsihrintzis; Ioannis Nalbantis; Show all 7 Authors
Araceae; Eichhornia crassipes; administrative management; agricultural pollution; agrochemicals; aquatic plants; fertilizers; pesticides; pollution control; solar radiation; water; water pollution
Abstract:
... Aiming to evaluate the efficacy of constructed floating wetlands (CFW) in removing agrochemicals (nutrients and pesticides), a series of experiments were run continuously for a 16-week period in pilot-scale CFW systems to study the effect of two aquatic plant species (duckweed and water hyacinth) and climatic parameters. The CFW systems were loaded daily with agricultural polluted water containing ...
... The global climate crisis precipitates a call to ‘futureproof’ cities by introducing resilient climate-adapted urban green infrastructure (UGI). Recent UK research has revealed public support for climate-adapted UGI, yet there is a lack of research focusing on the values underlying public perceptions, particularly in relation to climate change, and the socio-cultural factors driving these. This wa ...
capital; carbon; economic development; electric energy consumption; electricity; finance; power generation; renewable electricity; water power; Sub-Saharan Africa
Abstract:
... Despite the importance of cost of capital and expected returns from investing on renewable electricity generation in Africa on one hand and the implications of such investments on economic, social and environmental factors on the other. These concepts are not well understood by non-finance and finance actors respectively. Studies that analyze renewable energy-growth nexus at regional and global le ...
... Agri-environment schemes (AESs) have been developed by governments to improve biodiversity, reduce pollution from farming and encourage the provision of agriculture’s non-market benefits. Despite the substantial amount of money spent on designing, implementing and monitoring AESs, their environmental effectiveness is ambiguous. The objective of this paper is to investigate the relationship between ...
biodiversity; biodiversity conservation; ecosystems; people
Abstract:
... The Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) has become influential in biodiversity conservation. Its research is published widely and has been adopted by the United Nations and the Convention for Biological Diversity. This platform includes discussion about how values relate to biodiversity conservation. The IPBES emphasizes “relational values”, con ...
Lactobacillus; Macrobrachium rosenbergii; body weight; diet; growth performance; hemolymph; industry; juveniles; meta-analysis; postlarvae; probiotics; regression analysis; shrimp culture; specific growth rate; survival rate; variance; weight gain
Abstract:
... Probiotics are widely used in commercial shrimp aquaculture, but responses are variable. The objectives of this study were to quantitatively review using meta-analysis the production, survival, and immune responses of Macrobrachium rosenbergii to probiotics and to identify sources of residual variation. A total of 58 comparisons from 16 experiments (full text articles) were included in the final m ...
... Celebrities, including influencers, are commonly used to market products that are high in fat, sugar, and salt (HFSS) to children but the impact on dietary outcomes has been unclear. The primary aim of this study was to systematically review the literature and quantify the impact of celebrities in HFSS marketing on children’s dietary outcomes. We searched eight databases and included studies from ...
Helen Kaberi, et al. ; Amalia Prandekou; Maria Geraga; Spyros Sergiou; Dimitris Christodoulou; George Ferentinos; Constantin Koutsikopoulos; George Papatheodorou; Show all 8 Authors
... The evolution of the bottom water in Amvrakikos Gulf in Ionian Sea at western Greece for a 50-year timespan was assessed by benthic foraminifera assemblages. The degradation of the bottom water of Amvrakikos has been a catalyst for the surface water degradation. The east basin has shown permanent low environmental quality in bottom waters since 1980, while the west basin has been under seasonal hy ...