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- Pinlaor, Somchai, et al. Show all 11 Authors
- Biochemical and biophysical research communications 2012 v.421 no.2 pp. 280-285
- DNA; DNA damage; adenocarcinoma; antioxidants; biomarkers; esophagus; genes; immunohistochemistry; inducible nitric oxide synthase; patients; proton pump inhibitors; risk factors; risk reduction; tissues; transcription factor NF-kappa B
- ... Barrett’s esophagus (BE), an inflammatory disease, is a risk factor for Barrett’s esophageal adenocarcinoma (BEA). Treatment of BE patients with proton pump inhibitors (PPIs) is expected to reduce the risk of BEA. We performed an immunohistochemical study to examine the formation of nitrative and oxidative DNA lesions, 8-nitroguanine and 8-oxo-7,8-dihydro-2′-deoxygaunosine (8-oxodG), in normal eso ...