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- Hendriks, Jeanine A. A., et al. Show all 12 Authors
- Integrative biology 2013 v.5 no.6 pp. 889-898
- animal experimentation; biocompatible materials; cartilage; cattle; chondrocytes; coculture; drug development; ethics; extracellular matrix; humans; medical treatment; mesenchymal stromal cells; screening; tissue repair
- ... Animal experiments help to progress and ensure safety of an increasing number of novel therapies, drug development and chemicals. Unfortunately, these also lead to major ethical concerns, costs and limited experimental capacity. We foresee a coercion of all these issues by implantation of well systems directly into vertebrate animals. Here, we used rapid prototyping to create wells with biomateria ...
- Hendriks, Jeanine, et al. Show all 13 Authors
- Biomaterials 2015 v.44 pp. 122-133
- alginates; biocompatibility; biomechanics; bone marrow; cartilage; cell viability; cellulose; chondrocytes; endotoxins; humans; immunohistochemistry; mice; morphometry; porosity; porous media; tissue engineering
- ... Tissue engineering provides a promising alternative therapy to the complex surgical reconstruction of auricular cartilage by using ear-shaped autologous costal cartilage. Bacterial nanocellulose (BNC) is proposed as a promising scaffold material for auricular cartilage reconstruction, as it exhibits excellent biocompatibility and secures tissue integration. Thus, this study evaluates a novel bilay ...