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1. Changes in empyema among U.S. children in the pneumococcal conjugate vaccine era

Author:
Wiese, Andrew D.,   et al.   ; Griffin, Marie R.; Zhu, Yuwei; Mitchel, Edward F.; Grijalva, Carlos G.;     Show all 5 Authors
Source:
Vaccine 2016 v.34 no.50 pp. 6243-6249
ISSN:
0264-410X
Subject:
census data; children; confidence interval; etiology; pneumonia; serotypes; vaccines; United States
Abstract:
... Parapneumonic empyema, a serious complication of pneumonia, started increasing among U.S. children before the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in 2000, and continued afterwards. This increase was due in part to pneumococcal serotypes not included in PCV7 that were included in the new 13-valent (PCV13) vaccine introduced in 2010. We assessed changes in the incidenc ...
DOI:
10.1016/j.vaccine.2016.10.062