An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
algorithms; biodiversity; case studies; conservation areas; planning; prioritization; China
Abstract:
... Biodiversity hotspots at the global and national scale have contributed important information for biodiversity conservation; however, in hotspot designation two kinds of “gap” greatly limit conservation planning, which this study identifies as the “scale gap” and the “conservation gap”. To address the gap, we integrated systematic conservation planning (SCP) with gap analysis to optimize solutions ...
... Lung cancer is the leading cause of cancer death worldwide. Small-cell lung cancer (SCLC) is an aggressive type of lung cancer that shows an overall 5-year survival rate below 10%. Although chemotherapy using cisplatin has been proven effective in SCLC treatment, conventional dose of cisplatin causes adverse side effects. Photodynamic therapy, a form of non-ionizing radiation therapy, is increasin ...
... Quantitative real-time PCR (qRT-PCR) has become a routine and robust technique for measuring the expression of genes of interest, validating microarray experiments and monitoring biomarkers. However, concerns have been raised over the accuracy of qRT-PCR in China as well as in the rest of the world. We have previously used qRT-PCR to study the response of ANR1 and other root-expressed MADS-box gen ...
Burkholderia cepacia; biochemical pathways; biodegradation; carbon; dimethyl phthalate; energy; microorganisms; mineralization; models; pH; salinity; sediments; South China Sea
Abstract:
... Burkholderia cepacia DA2, isolated from marine sediment of the South China Sea, is capable of utilizing dimethyl phthalate (DMP) as the sole source of carbon and energy. During the transformation of DMP in batch culture, its corresponding degradation intermediates were identified as monomethyl phthalate (MMP) and phthalate acid (PA) sequentially over the time of incubation. The biodegradation bioc ...
... In recent years, methicillin-resistant Staphylococcus aureus (MRSA) has become one of the most common multi-drug resistant bacteria in both hospital and community. The aim of this study is to investigate the selective inhibition of MRSA by a modified photosensitizer (LAEtNBS) in vitro and the efficacy of MRSA infection treatment by photodynamic therapy (PDT) with LAEtNBS in vivo. LAEtNBS was synth ...
Danio rerio; active sites; bioinformatics; consensus sequence; histidine; hydrolysis; mass spectrometry; proteins; serine; serine proteinases
Abstract:
... Seryl-histidine dipeptide (Ser-His) has been recognized as the shortest peptide with hydrolysis cleavage activity; however, its protein cleavage spectrum has not yet been fully explored. Here, four differently folded proteins were treated with Ser-His, and the digestion products were evaluated with high-resolution mass spectrometry. The cleavage efficiency and cleavage propensity of Ser-His agains ...
biogeography; conservation areas; databases; ecologists; geographic information systems; geographical distribution; mountains; species diversity; wild plants; China
Abstract:
... Large scale heterogeneous distribution of biodiversity has become a hot topic for ecologists and conservationists. A threat status assessment combined with geographic distribution patterns of threatened plants in China has been conducted at a national scale in this study based upon a distribution database that refers to both specimen records and published references. Currently, 302 threatened plan ...
... A readily available and highly modular class of chiral P,N,N-ligands based on a structurally flexible nonchiral phosphine-amine framework with an optically active 1,2-diphenylethylenediamine unit bearing a tertiary amine terminus as the chiral source have been developed and successfully applied in the Ir-catalyzed asymmetric hydrogenation of o-amidophenyl ketones. These tridentate P,N,N-ligands ex ...
... Metal oxides have attracted renewed interest in applications as energy storage and conversion devices. Here, a new design is reported to acquire an asymmetric supercapacitor assembled by all free-standing metal oxides. The positive electrode is made of 3D NiO open porous nanoribbons network on nickel foam and the negative electrode is composed of SnO₂/MnO₂ nanoflakes grown on carbon cloth (CC) sub ...
algorithms; animals; biogeography; conservation areas; extinction; habitat fragmentation; habitat preferences; mountains; planning; species diversity; threatened species; wild plants; China
Abstract:
... Habitat fragmentation and loss is the main cause of species extinction; thus, the appropriate placement of protected areas is critical for saving vulnerable and threatened species. However, how to expand the existing protected areas network for improving conservation efficiency is a vital concern. We examined the Qinling Mountains — a widely recognized biogeographic treasure in China and East Asia ...
... Cotton plants accumulate gossypol and related sesquiterpene aldehydes, which function as phytoalexins against pathogens and feeding deterrents to herbivorous insects. However, to date little is known about the biosynthesis of volatile terpenes in this crop. Herein is reported that 5 monoterpenes and 11 sesquiterpenes from extracts of a glanded cotton cultivar, Gossypium hirsutum cv. CCRI12, were d ...
... A membrane-bound protein purified from Gluconobacter oxydans M5 was confirmed to be a pyrroloquinoline quinone-dependent D-sorbitol dehydrogenase. Gene disruption and complementation experiments demonstrated that this enzyme is responsible for the oxidation of 1-(2-hydroxyethyl) amino-1-deoxy-D-sorbitol (1NSL) to 6-(2-hydroxyethyl) amino-6-deoxy-L-sorbose (6NSE), which is the precursor of an antid ...
... Surface sediments were collected from three mangrove wetlands (Yifeng Xi, Shuanghan, and Su’ai Wan) in Shantou coastal zone of South China to investigate spatial distributions of polybrominated diphenyl ethers (PBDEs). The results demonstrate that PBDEs were detected in all the samples, indicating their widespread occurrence in coastal sediments of the studied area. Σ₉PBDEs (defined as the sum of ...
Chinese people; atherosclerosis; body mass index; confidence interval; correlation; diastolic blood pressure; disease control; humans; hyperlipidemia; immune response; long term effects; men; patients; regression analysis; risk factors; schistosomiasis; triacylglycerols; uric acid; vaccines; waist circumference; China
Abstract:
... The major purpose of this study was to assess the association between the potential long-term effects of previous schistosome infection and atherogenic dyslipidemia. Among 1597 men aged ⩾45years who received health examinations and lived in previous schistosomiasis-endemic regions of China, 465 patients with previous schistosome infection were selected as study subjects, and 1132 subjects formed t ...
... The effects of sophorolipid on the growth and apoptosis of H7402 human liver cancer cells were investigated. By treatment with sophorolipid, a dose- and time-dependent inhibition of cell proliferation was observed. The cells developed many features of apoptosis, including condensation of chromatin, nuclear fragmentation, and appearance of apoptotic bodies, and terminal deoxynucleotidyl transferase ...
... As the typical unconventional reservoir, shale gas is believed to be the most promising alternative for the conventional resources in future energy patterns, attracting more and more attention throughout the world. Generally, the majority of shale gas is trapped within the tight shale rock with ultralow porosity (<10%) and ultrasmall pore size (as less as several nanometers). Thus, the accurate un ...
Yin-Bo Zhu, et al. ; Xiaofang Chen; Hao Yu; Jefferson Zhe Liu; Christopher D. Easton; Zhouyou Wang; Yaoxin Hu; Zongli Xie; Heng-An Wu; Xiwang Zhang; Dan Li; Huanting Wang; Show all 12 Authors
... Controlling the pore sizes of graphene-based membranes is essential for exploring their transport properties and related applications such as water desalination. We demonstrated the scalable fabrication of ultrathin graphene membranes with precisely controlled subnanometer pores by co-assembly of graphene oxide nanosheet and polymer on a porous ceramic substrate and subsequent reduction and carbon ...
... Usnic acid (UA) is a secondary metabolite of lichens with a unique dibenzofuran scaffold. The growth inhibitory and apoptotic effects of UA as well as the potential mechanisms of action were determined in human acute myeloid leukemia HL-60 cells and chronic myeloid leukemia K562 cells. UA inhibits growth and induces apoptosis in both cell lines with HL-60 cells more responsive. The apoptotic effec ...