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1. Biocompatible bacteria@Au composites for application in the photothermal destruction of cancer cells

Author:
Chen, Szu-Yu,   et al.   ; Kuo, Wen-Shuo; Wu, Ching-Ming; Yang, Zih-Syuan; Chen, Cheng-Ying; Huang, Chih-Chia; Li, Wei-Ming; Sun, Chi-Kuang; Yeh, Chen-Sheng;     Show all 9 Authors
Source:
Chemical communications 2008 no.37 pp. 4430-4432
ISSN:
1364-548X
Subject:
Escherichia coli; bacteria; chemical communication; chemical reactions; gold; neoplasm cells; neoplasms; photothermotherapy
Abstract:
... We have successfully transformed the infectious E. coli bacteria into biocompatible bacteria@Au composites for photothermal therapy. ...
DOI:
10.1039/b808871c

2. Delayed animal aging through the recovery of stem cell senescence by platelet rich plasma

Author:
Tina Chen, Szu-Yu,   et al.   ; Liu, Hen-Yu; Huang, Chiung-Fang; Lin, Tzu-Chieh; Tsai, Ching-Yu; Liu, Alice; Chen, Wei-Hong; Wei, Hong-Jian; Wang, Ming-Fu; Williams, David F.; Deng, Win-Ping;     Show all 11 Authors
Source:
Biomaterials 2014 v.35 pp. 9767-9776
ISSN:
0142-9612
Subject:
adipogenesis; alternative medicine; body weight; bone formation; bone marrow; cell growth; cell proliferation; cell senescence; fibroblasts; longevity; mice; oxidative stress; phenotype; stem cells; tissue repair
Abstract:
... Aging is related to loss of functional stem cell accompanying loss of tissue and organ regeneration potentials. Previously, we demonstrated that the life span of ovariectomy-senescence accelerated mice (OVX-SAMP8) was significantly prolonged and similar to that of the congenic senescence-resistant strain of mice after platelet rich plasma (PRP)/embryonic fibroblast transplantation. The aim of this ...
DOI:
10.1016/j.biomaterials.2014.08.034

3. Detecting Bakanae disease in rice seedlings by machine vision

Author:
Chen, Szu-Yu,   et al.   ; Chung, Chia-Lin; Huang, Kai-Jyun; Lai, Ming-Hsing; Chen, Yu-Chia; Kuo, Yan-Fu;     Show all 6 Authors
Source:
Computers and electronics in agriculture 2016 v.121 pp. 404-411
ISSN:
0168-1699
Subject:
Fusarium fujikuroi; Oryza sativa; color; computer vision; conidia; cultivars; grain yield; inflorescences; pathogens; rice; scanners; seed-borne diseases; seedlings; seeds; support vector machines
Abstract:
... Bakanae disease, or “foolish seedling”, is a seed-borne disease of rice (Oryza sativa L.). Infected plants can yield empty panicles or perish, resulting in a loss of grain yield. The disease occurs most frequently when contaminated seeds are used. Once the seeds are contaminated, the pathogen Fusarium fujikuroi spreads in the field. Therefore, infected plants must be screened at early developmenta ...
DOI:
10.1016/j.compag.2016.01.008

4. Genome-wide association mapping of gene loci affecting disease resistance in the rice-Fusarium fujikuroi pathosystem

Author:
Chen, Szu-Yu,   et al.   ; Lai, Ming-Hsin; Tung, Chih-Wei; Wu, Dong-Hong; Chang, Fang-Yu; Lin, Tsung-Chun; Chung, Chia-Lin;     Show all 7 Authors
Source:
Rice 2019 v.12 no.1 pp. 85
ISSN:
1939-8425
Subject:
Fusarium fujikuroi; Oryza sativa; chromosome mapping; disease resistance; disease severity; genes; genome-wide association study; germplasm; grain yield; inbred lines; loci; quantitative trait loci; resistance mechanisms; rice; seedlings; stems; transcription factors; virulence; Asia
Abstract:
... BACKGROUND: Rice bakanae disease has emerged as a new threat to rice production. In recent years, an increase in the occurrence and severity of bakanae disease has been reported in several areas in Asia. Although bakanae disease affects rice yield and quality, little is known about the genetics of bakanae resistance in rice. The lack of large-scale screens for bakanae resistance in rice germplasm ...
DOI:
10.1186/s12284-019-0337-3
PubMed:
31754813
PubMed Central:
PMC6872702

5. Genome-wide association study of rice genes and loci conferring resistance to Magnaporthe oryzae isolates from Taiwan

Author:
Chen, Szu-Yu,   et al.   ; Lin, Heng-An; Chang, Fang-Yu; Tung, Chih-Wei; Chen, Yi-Chia; Shen, Wei-Chiang; Chen, Ruey-Shyang; Wu, Chih-Wen; Chung, Chia-Lin;     Show all 9 Authors
Source:
Botanical studies 2018 v.59 no.1 pp. 32
ISSN:
1999-3110
Subject:
Magnaporthe oryzae; blast disease; breeding; computer software; genes; genome-wide association study; genotyping; haplotypes; image analysis; leaf area; leaves; loci; peroxidases; phenotype; quantitative trait loci; rice; single nucleotide polymorphism; transcription factors; Taiwan
Abstract:
... BACKGROUND: Rice blast, caused by Magnaporthe oryzae, is an important rice disease occurring in all rice-growing areas. To manage blast disease effectively and in an environmentally friendly way, it is important to continually discover diverse resistant resources for breeding. In this study, genome-wide association study (GWAS) was used to map genes/loci resistant to rice blast in the open-access ...
DOI:
10.1186/s40529-018-0248-4
PubMed:
30578469
PubMed Central:
PMC6303224

6. Identifying rice grains using image analysis and sparse-representation-based classification

Author:
Chen, Szu-Yu,   et al.   ; Kuo, Tzu-Yi; Chung, Chia-Lin; Lin, Heng-An; Kuo, Yan-Fu;     Show all 5 Authors
Source:
Computers and electronics in agriculture 2016 v.127 pp. 716-725
ISSN:
0168-1699
Subject:
Oryza sativa; color; image analysis; microscopy; rice; staple foods
Abstract:
... Rice (Oryza sativa L.) is a major staple food worldwide, and is traded extensively. The objective of this study is to distinguish the rice grains of 30 varieties nondestructively using image processing and sparse-representation-based classification (SRC). SRC uses over-complete bases to capture the representative traits of rice grains. In the experiments, rice grain images were acquired by microsc ...
DOI:
10.1016/j.compag.2016.07.020

7. Physicochemical and functional properties of Chinese soft-shell turtle (Pelodiscus sinensis) egg

Author:
Chen, Szu-Yu,   et al.   ; Kuo, Meng-I;     Show all 2 Author
Source:
Food research international 2016 v.85 pp. 36-43
ISSN:
0963-9969
Subject:
Pelodiscus sinensis; egg albumen; egg yolk; eggs; emulsifying; foaming properties; food industry; freeze drying; granules; hens; lipids; lysozyme; pH; protein solubility; turtles
Abstract:
... The physicochemical properties of Chinese soft-shell turtle egg were characterized for functional use in the food industry. The egg yolk of un-fertilized soft-shell turtle eggs was separated and fractionated into granules and plasma. Then, the egg yolk, albumen, granules, and plasma were freeze-dried for further analysis. Results showed that the Chinese soft-shell turtle egg typically comprised 50 ...
DOI:
10.1016/j.foodres.2016.04.013

8. Random-Coil Behavior of Chemically Denatured Topologically Knotted Proteins Revealed by Small-Angle X-ray Scattering B

Author:
Chen, Szu-Yu,   et al.   ; Shih, Po-Min; Wang, Iren; Lee, Yun-Tzai Cloud; Hsieh, Shu-Ju; Wang, Liang-Wei; Huang, Chih-Ting; Chien, Chih-Ta; Chang, Chia-Yun; Hsu, Shang-Te Danny;     Show all 10 Authors
Source:
The Journal of physical chemistry 2015 v.119 no.17 pp. 5437-5443
ISSN:
1520-5207
Subject:
X-radiation; physical chemistry; polypeptides; proteins; stereoisomerism; topology
Abstract:
... Recent studies on the mechanisms by which topologically knotted proteins attain their natively knotted structures have intrigued theoretical and experimental biophysicists. Of particular interest is the finding that YibK and YbeA, two small trefoil knotted proteins, remain topologically knotted in their chemically denatured states. Using small-angle X-ray scattering (SAXS), we examine whether thes ...
DOI:
10.1021/acs.jpcb.5b01984

9. Synergistic anabolic actions of hyaluronic acid and platelet-rich plasma on cartilage regeneration in osteoarthritis therapy

Author:
Tina Chen, Szu-Yu,   et al.   ; Chen, Wei-Hong; Lo, Wen-Cheng; Hsu, Wei-Che; Wei, Hong-Jian; Liu, Hen-Yu; Lee, Chian-Her; Shieh, Ying-Hua; Williams, David F.; Deng, Win-Ping;     Show all 10 Authors
Source:
Biomaterials 2014 v.35 no.36 pp. 9599-9607
ISSN:
0142-9612
Subject:
cartilage; chemokines; chondrocytes; genes; homeostasis; hyaluronic acid; immunoblotting; inflammation; models; osteoarthritis; patients; phenotype; receptors; reverse transcriptase polymerase chain reaction; signal transduction; therapeutics; tissue repair; transcription factors
Abstract:
... Osteoarthritis (OA) is a common disease associated with tissue inflammation, physical disability and imbalanced homeostasis in cartilage. For advanced treatments, biological approaches are currently focused on tissue regeneration and anti-inflammation. This study was undertaken to evaluate the therapeutic efficacies of hyaluronic acid (HA) and platelet-rich plasma (PRP) (HA+PRP) on OA. Articular c ...
DOI:
10.1016/j.biomaterials.2014.07.058

10. The role of the ERK1/2 pathway as an alternative to the aging-diminished cyclic AMP pathway in calcitonin-mediated chondrogenesis in human nucleus pulposus

Author:
Tina Chen, Szu-Yu,   et al.   ; Chen, Wei-Hong; Zeng, Rong; Lo, Wen-Cheng; Lai, Tung-Yuan; Williams, David F.; Deng, Win-Ping;     Show all 7 Authors
Source:
Biomaterials 2012 v.33 no.33 pp. 8256-8264
ISSN:
0142-9612
Subject:
calcitonin; calcitonin receptors; chondrogenesis; cyclic AMP; humans; phenotype; signal transduction; therapeutics
Abstract:
... Human disc degeneration initiated by aging in the central nucleus pulposus (hNP) is an irreversible process and the recovery has become seriously emerging. In this study, the related mechanisms of calcitonin on the regeneration of hNP and the effects of calcitonin on the age-related alterations were examined. The harvested hNP population was designated as YhNP (from young donor, age <50) and OhNP ...
DOI:
10.1016/j.biomaterials.2012.06.088

11. Unraveling the Folding Mechanism of the Smallest Knotted Protein, MJ0366 B

Author:
Chen, Szu-Yu,   et al.   ; Wang, Iren; Hsu, Shang-Te Danny;     Show all 3 Authors
Source:
The Journal of physical chemistry 2015 v.119 no.12 pp. 4359-4370
ISSN:
1520-5207
Subject:
Methanocaldococcus jannaschii; denaturation; dissociation; models; nitrogen; nuclear magnetic resonance spectroscopy; polypeptides; proteins; stable isotopes
Abstract:
... Understanding the mechanism by which polypeptide chains thread themselves into topologically knotted structures has emerged to be a challenging subject not least because of the additional complexity associated with the spontaneous and efficient knotting and folding events. While recent theoretical calculations have made significant progress in establishing the atomistic folding pathways for a numb ...
DOI:
10.1021/jp511029s