Jump to Main Content
- Sim, Iain, et al. Show all 11 Authors
- Vaccine 2011 v.29 no.37 pp. 6313-6320
- DNA; adjuvants; agonists; animals; anthrax; antigens; blood serum; clinical trials; disease control; enzyme-linked immunosorbent assay; immune response; immunization; immunoglobulin G; models; oligodeoxyribonucleotides; spores; vaccines; volunteers
- ... Immunization with BioThrax® (Anthrax Vaccine Adsorbed) is a safe and effective means of preventing anthrax. Animal studies have demonstrated that the addition of CpG DNA adjuvants to BioThrax can markedly increase the immunogenicity of the vaccine, increasing both serum anti-protective antigen (PA) antibody and anthrax toxin-neutralizing antibody (TNA) concentrations. The immune response to CpG-ad ...