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1. Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging

Author:
Stadler, Krisztian,   et al.   ; Ma, Xiaojun; Lin, Ligen; Qin, Guijun; Lu, Xinping; Fiorotto, Marta; Dixit, Vishwa D.; Sun, Yuxiang;     Show all 8 Authors
ISSN:
1932-6203
Subject:
appetite; body composition; brown adipose tissue; cold; energy expenditure; fasting; food intake; ghrelin; ghrelin receptors; locomotion; mice; obesity; phenotype; secretion; signal transduction
Abstract:
... Obesity is a hallmark of aging in many Western societies, and is a precursor to numerous serious age-related diseases. Ghrelin (Ghrl) , via its receptor (growth hormone secretagogue receptor, GHS-R), is shown to stimulate GH secretion and appetite. Surprisingly, our previous studies showed that Ghrl -/- mice have impaired thermoregulatory responses to cold and fasting stresses, while Ghsr -/- mice ...
DOI:
10.1371/journal.pone.0016391
PubMed:
21298106
PubMed Central:
PMC3027652

2. Absorption of 3(2H)-Furanones by Human Intestinal Epithelial Caco-2 Cells

Author:
Stadler, Nicole Christina,   et al.   ; Somoza, Veronika; Schwab, Wilfried;     Show all 3 Authors
Source:
Journal of agricultural and food chemistry 2009 v.57 no.9 pp. 3949-3954
ISSN:
0021-8561
Subject:
intestinal absorption; human cell lines; intestinal mucosa; furans; nutrition physiology
Abstract:
... A number of 3(2H)-furanones are synthesized by fruits and have been found in cooked foodstuffs, where they impart flavor and odor because of their low perception thresholds. They show genotoxic properties in model studies but are also ranked among the antioxidants and anticarcinogens. This study examined the efficiency of intestinal absorption and metabolic conversion of 3(2H)-furanones by using C ...
DOI:
10.1021/jf9001704
PubMed:
19338346

3. Accurate and efficient reconstruction of deep phylogenies from structured RNAs

Author:
Stadler, Peter F.,   et al.   ; Stocsits, Roman R.; Letsch, Harald; Hertel, Jana; Misof, Bernhard;     Show all 5 Authors
Source:
Nucleic acids research 2009 v.37 no.18 pp. 6184-6193
ISSN:
0305-1048
Subject:
Bayesian theory; Echinodermata; Mammalia; data collection; genes; mitochondria; models; phylogeny; ribosomal RNA
Abstract:
... Ribosomal RNA (rRNA) genes are probably the most frequently used data source in phylogenetic reconstruction. Individual columns of rRNA alignments are not independent as a consequence of their highly conserved secondary structures. Unless explicitly taken into account, these correlation can distort the phylogenetic signal and/or lead to gross overestimates of tree stability. Maximum likelihood and ...
DOI:
10.1093/nar/gkp600
PubMed:
19723687
PubMed Central:
PMC2764418

4. Accurate annotation of protein-coding genes in mitochondrial genomes

Author:
Stadler, Peter F.,   et al.   ; Al Arab, Marwa; Höner zu Siederdissen, Christian; Tout, Kifah; Sahyoun, Abdullah H.; Bernt, Matthias;     Show all 6 Authors
Source:
Molecular phylogenetics and evolution 2017 v.106 pp. 209-216
ISSN:
1055-7903
Subject:
Markov chain; genes; mitochondria; mitochondrial genome; nucleotide sequences; phylogeny; sequence alignment
Abstract:
... Mitochondrial genome sequences are available in large number and new sequences become published nowadays with increasing pace. Fast, automatic, consistent, and high quality annotations are a prerequisite for downstream analyses. Therefore, we present an automated pipeline for fast de novo annotation of mitochondrial protein-coding genes. The annotation is based on enhanced phylogeny-aware hidden M ...
DOI:
10.1016/j.ympev.2016.09.024

5. Accurate mapping of tRNA reads

Author:
Stadler, Peter F,   et al.   ; Hoffmann, Anne; Fallmann, Jörg; Vilardo, Elisa; Mörl, Mario; Amman, Fabian; Sahinalp, Cenk;     Show all 7 Authors
Source:
Bioinformatics 2018 v.34 no.7 pp. 1116-1124
ISSN:
1460-2059
Subject:
DNA; RNA precursors; bioinformatics; genome; genomics; loci; nucleotide sequences; sequence analysis; transcription (genetics); transfer RNA
Abstract:
... Many repetitive DNA elements are transcribed at appreciable expression levels. Mapping the corresponding RNA sequencing reads back to a reference genome is notoriously difficult and error-prone task, however. This is in particular true if chemical modifications introduce systematic mismatches, while at the same time the genomic loci are only approximately identical, as in the case of tRNAs. We the ...
DOI:
10.1093/bioinformatics/btx756

6. Achieving phase transformation and structure control of crystalline anatase TiO2@C hybrids from titanium glycolate precursor and glucose molecules

Author:
Stadler, Florian J.,   et al.   ; Cheng, Gang;     Show all 2 Author
Source:
Journal of colloid and interface science 2015 v.438 pp. 169-178
ISSN:
0021-9797
Subject:
Raman spectroscopy; X-ray diffraction; X-ray photoelectron spectroscopy; adsorption; carbon; crystallites; energy; glucose; hydrothermal carbonization; nanopores; phase transition; photocatalysis; photocatalysts; scanning electron microscopy; thermogravimetry; titanium; transmission electron microscopy
Abstract:
... Considerable efforts have focused on functional TiO2@carbonaceous hybrid nanostructured materials (TiO2@C) to satisfy the future requirements of environmental photocatalysis and energy storage using these advanced materials. In this study, we developed a two-step solution-phase reaction to prepare hybrid TiO2@C with tuneable structure and composition from the hydrothermal carbonization (HTC) of gl ...
DOI:
10.1016/j.jcis.2014.09.084

7. Achromobacter animicus sp. nov., Achromobacter mucicolens sp. nov., Achromobacter pulmonis sp. nov. and Achromobacter spiritinus sp. nov., from human clinical samples

Author:
Svensson-Stadler, Liselott,   et al.   ; Vandamme, Peter; Moore, Edward R.B.; Cnockaert, Margo; De Brandt, Evie; Houf, Kurt; Spilker, Theodore; LiPuma, John J.;     Show all 8 Authors
Source:
Systematic and applied microbiology 2013 v.36 no.1 pp. 1-10
ISSN:
0723-2020
Subject:
Achromobacter ruhlandii; humans; loci; new species; phenotype; sequence analysis
Abstract:
... The phenotypic and genotypic characteristics of fourteen human clinical Achromobacter strains representing four genogroups which were delineated by sequence analysis of nusA, eno, rpoB, gltB, lepA, nuoL and nrdA loci, demonstrated that they represent four novel Achromobacter species. The present study also characterized and provided two additional reference strains for Achromobacter ruhlandii and ...
DOI:
10.1016/j.syapm.2012.10.003

8. A comprehensive analysis of bilaterian mitochondrial genomes and phylogeny

Author:
Stadler, Peter F.,   et al.   ; Bernt, Matthias; Bleidorn, Christoph; Braband, Anke; Dambach, Johannes; Donath, Alexander; Fritzsch, Guido; Golombek, Anja; Hadrys, Heike; Jühling, Frank; Meusemann, Karen; Middendorf, Martin; Misof, Bernhard; Perseke, Marleen; Podsiadlowski, Lars; von Reumont, Björn; Schierwater, Bernd; Schlegel, Martin; Schrödl, Michael; Simon, Sabrina; Stöger, Isabella; Struck, Torsten H.;     Show all 22 Authors
Source:
Molecular phylogenetics and evolution 2013 v.69 no.2 pp. 352-364
ISSN:
1055-7903
Subject:
amino acid substitution; data collection; databases; expressed sequence tags; nucleotides; phylogeny; amino acids; vertebrates; Nematoda; Mollusca; Platyhelminthes; Hexapoda
Abstract:
... About 2800 mitochondrial genomes of Metazoa are present in NCBI RefSeq today, two thirds belonging to vertebrates. Metazoan phylogeny was recently challenged by large scale EST approaches (phylogenomics), stabilizing classical nodes while simultaneously supporting new sister group hypotheses. The use of mitochondrial data in deep phylogeny analyses was often criticized because of high substitution ...
DOI:
10.1016/j.ympev.2013.05.002
PubMed:
23684911

9. Adaptive allocation of resources and life-history trade-offs in aphids relative to plant quality

Author:
Stadler, B.
Source:
Oecologia 1995 v.102 no.2 pp. 246-254
ISSN:
0029-8549
Subject:
reproduction; food plants; Uroleucon; progeny; life cycle (organisms); Centaurea jacea
DOI:
10.1007/BF00333257

10. A Detailed Model on Kinetics and Microstructure Evolution during Copolymerization of Ethylene and 1-Octene: From Coordinative Chain Transfer to Chain Shuttling Polymerization

Author:
Stadler, Florian J.,   et al.   ; Mohammadi, Yousef; Ahmadi, Mostafa; Saeb, Mohammad Reza; Khorasani, Mohammad Mehdi; Yang, Pianpian;     Show all 6 Authors
Source:
Macromolecules 2014 v.47 no.14 pp. 4778-4789
ISSN:
1520-5835
Subject:
catalysts; chemical composition; composite polymers; computer software; copolymerization; ethylene; hydrogen; microstructure; molecular weight; theoretical models
Abstract:
... We introduce a theoretical model based upon the kinetic Monte Carlo (KMC) simulation approach capable of quantifying chain shuttling copolymerization (CSP) of ethylene and 1-octene in a semibatch operation. To make a deeper understanding of kinetics and evolution of microstructure, the reversible transfer reaction is first investigated by applying each of the individual catalysts to the reaction m ...
DOI:
10.1021/ma500874h

11. Adsorption of Tetrammine-carbonato and -cis-diaqua and Triethylenetetramine-carbonato and -cis-diaqua Complexes of Cobalt(III) on Titanium Dioxide as Models for the Binding of Uranyl Ions from the Tricarbonatouranyl Complex Ion

Author:
Stadler, K. H.,   et al.   ; Lauerer, Brigitte; Pusch, A.; Boehm, H. P.;     Show all 4 Authors
Source:
Zeitschrift für Naturforschung 2014 v.47 no.5 pp. 625-634
ISSN:
0932-0776
Subject:
adsorption; aluminum; ambient temperature; ammonia; carbonates; cobalt; ions; ligands; models; oxygen; phosphates; reflectance spectroscopy; titanium dioxide; vacuum drying
Abstract:
... The adsorption of several cobalt(III) complex ions with carbonato or two aqua ligands in cis-position (and related complexes) was studied with the objective of a comparison with the adsorption of UO₂²⁺ ions from [UO₂(CO₃)₃]⁴⁻ solutions. One CO₃²⁻ group per adsorbed UO₂²⁺ ion was found on the TiO₂ surface after vacuum-drying at room temperature. Pre-adsorption of HPO₄²⁻ ions resulted in an increase ...
DOI:
10.1515/znb-1992-0504

12. A dual switch in phloem unloading during ovule development in Arabidopsis

Author:
Stadler, Ruth,   et al.   ; Werner, Dagmar; Gerlitz, Nadja;     Show all 3 Authors
Source:
Protoplasma 2011 v.248 no.1 pp. 225-235
ISSN:
0033-183X
Subject:
Arabidopsis thaliana; ovules; transport proteins; flowering; energy; fruits; plasmodesmata; fluorescence; flowers; phloem; symplast; tracer techniques; leaves
Abstract:
... Developing flowers are important sinks in Arabidopsis thaliana. Their energy demand is covered by assimilates which are synthesized in source leaves and transported via the vasculature. Assimilates are unloaded either symplastically through plasmodesmata or apoplastically by specific transport proteins. Here we studied the pathway of phloem unloading and post-phloem transport in developing gynoeci ...
DOI:
10.1007/s00709-010-0223-8

13. Aerogels and metal–organic frameworks for environmental remediation and energy production

Author:
Stadler, Florian J.,   et al.   ; Kumar, Amit; Rana, Anamika; Sharma, Gaurav; Sharma, Shweta; Naushad, Mu.; Mola, Genene Tessema; Dhiman, Pooja;     Show all 8 Authors
Source:
Environmental chemistry letters 2018 v.16 no.3 pp. 797-820
ISSN:
1610-3653
Subject:
aerogels; air; carbon dioxide; climate change; coordination polymers; energy; heavy metals; hydrogen; ligands; metal ions; methane; nitrogen oxides; photolysis; pollutants; pollution; porosity; remediation; renewable energy sources; surface area
Abstract:
... Environmental pollution and climate change are requiring new methods to clean pollutants and produce sustainable energy. Aerogels and metal organic frameworks are emerging as advanced porous materials with higher functionality, high surface area, high porosity and flexible chemistry. Aerogels are dried gels prepared using the sol–gel procedure, whereas metal organic frameworks are networks of orga ...
DOI:
10.1007/s10311-018-0723-x

14. Aetheramides A and B, Potent HIV-Inhibitory Depsipeptides from a Myxobacterium of the New Genus “Aetherobacter”

Author:
Stadler, Marc,   et al.   ; Plaza, Alberto; Garcia, Ronald; Bifulco, Giuseppe; Martinez, Javier Pablo; Hüttel, Stephan; Sasse, Florenz; Meyerhans, Andreas; Müller, Rolf;     Show all 9 Authors
Source:
Organic letters 2012 v.14 no.11 pp. 2854-2857
ISSN:
1523-7052
Subject:
HIV infections; Human immunodeficiency virus 1; amino acids; chemical reactions; colorectal neoplasms; depsipeptides; humans; inhibitory concentration 50; moieties; new genus; nuclear magnetic resonance spectroscopy; polyketides; quantum mechanics
Abstract:
... Aetheramides are structurally distinctive cyclic peptides isolated from a novel myxobacterial genus proposed to be termed “Aetherobacter”. The structures were solved by a combination of NMR analyses, quantum mechanical calculations, and chemical derivatizations. Aetheramides which contain a unique polyketide moiety and two amino acid residues potently inhibited HIV-1 infection with IC₅₀ values of ...
DOI:
10.1021/ol3011002

15. A facile and general synthesis strategy to doped TiO₂ nanoaggregates with a mesoporous structure and comparable property

Author:
Stadler, Florian J.,   et al.   ; Cheng, Gang; Xu, Feifan; Chen, Rong;     Show all 4 Authors
Source:
RSC advances 2015 v.5 no.79 pp. 64293-64298
ISSN:
2046-2069
Subject:
cobalt; nanoparticles; nickel; photocatalysis; porous media; salts; titanium; titanium dioxide
Abstract:
... A facile and general route was explored to fabricate porous metal-doped TiO₂ nanoaggregates from a titanium glycolate precursor and metal salts, in which the metal salts not only provide the dopant precursor but also favor the formation of a porous structure. The as-prepared Co–TiO₂ and Ni–TiO₂ nanoaggregates showed higher photocatalytic performance than pure TiO₂ nanoparticles, P25, and Zn–TiO₂ n ...
DOI:
10.1039/c5ra11099h

16. A facile polyol-mediated approach to tunable CeO₂ microcrystals and their photocatalytic activity

Author:
Stadler, Florian J.,   et al.   ; Cheng, Gang; Xiong, Jinyan;     Show all 3 Authors
Source:
Powder technology 2013 v.249 pp. 89-94
ISSN:
0032-5910
Subject:
solar radiation; X-ray diffraction; polyols; absorption; reflectance spectroscopy; scanning electron microscopy; solvents; transmission electron microscopy; irradiation; oleic acid; photocatalysts
Abstract:
... An efficient solvothermal method was developed to prepare CeO₂ microcrystals with different shapes using a polyol–ethanol mixed solvent as the reaction medium. The as-synthesized product was characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), selected area electron diffraction (SAED), and UV–vis diffuse reflectance spectrosco ...
DOI:
10.1016/j.powtec.2013.07.033

17. Agarose-based biomaterials for advanced drug delivery

Author:
Stadler, Florian J.,   et al.   ; Khodadadi Yazdi, Mohsen; Taghizadeh, Ali; Taghizadeh, Mohsen; Farokhi, Mehdi; Mottaghitalab, Fatemeh; Zarrintaj, Payam; Ramsey, Joshua D.; Seidi, Farzad; Saeb, Mohammad Reza; Mozafari, Masoud;     Show all 11 Authors
Source:
Journal of controlled release 2020 v.326 pp. 523-543
ISSN:
0168-3659
Subject:
agarose; bioactive properties; biocompatible materials; chemical reactions; drug delivery systems; drugs; mechanical properties
Abstract:
... Agarose is a prominent marine polysaccharide representing reversible thermogelling behavior, outstanding mechanical properties, high bioactivity, and switchable chemical reactivity for functionalization. As a result, agarose has received particular attention in the fabrication of advanced delivery systems as sophisticated carriers for therapeutic agents. The ever-growing use of agarose-based bioma ...
DOI:
10.1016/j.jconrel.2020.07.028

18. Aggregicoccus edonensis gen. nov., sp. nov., an unusually aggregating myxobacterium isolated from a soil sample

Author:
Stadler, Marc,   et al.   ; Sood, Sakshi; Awal, Ram Prasad; Wink, Joachim; Mohr, Kathrin I.; Rohde, Manfred; Kämpfer, Peter; Glaeser, Stefanie P.; Schumann, Peter; Garcia, Ronald; Müller, Rolf;     Show all 11 Authors
Source:
International journal of systematic and evolutionary microbiology 2015 v.65 no.Pt 3 pp. 745-753
ISSN:
1466-5034
Subject:
Corallococcus exiguus; DNA; Stigmatella; bacitracin; cephalosporins; fatty acids; gentamicin; hydrolysates; hygromycin B; kanamycin; matrix-assisted laser desorption-ionization mass spectrometry; new genus; new species; nucleic acid hybridization; nucleotide sequences; nutrition; phylogeny; polymyxins; ribosomal RNA; sequence homology; soil; vegetative cells; Japan; Switzerland
Abstract:
... A novel myxobacterium, MCy1366 ᵀ (Ar1733), was isolated in 1981 from a soil sample collected from a region near Tokyo, Japan. It displayed general myxobacterial features like Gram-negative-staining, rod-shaped vegetative cells, gliding on solid surfaces, microbial lytic activity, fruiting-body-like aggregates and myxospore-like structures. The strain was mesophilic, aerobic and showed a chemoheter ...
DOI:
10.1099/ijs.0.061176-0

19. A hypothesis on physiological alterations during plant ontogenesis governing susceptibility of winter barley to ramularia leaf spot

Author:
Stadler, M.,   et al.   ; Schützendübel, A.; Wallner, D.; von Tiedemann, A.;     Show all 4 Authors
Source:
Plant pathology 2008 v.57 no.3 pp. 518-526
ISSN:
0032-0862
Subject:
Hordeum vulgare; Ramularia; antioxidants; conidia; developmental stages; environmental factors; enzyme activity; enzyme-linked immunosorbent assay; fungi; glutathione; glutathione dehydrogenase (ascorbate); glutathione-disulfide reductase; inoculum; leaf spot; leaves; lignification; meteorological data; monodehydroascorbate reductase (NADH); ontogeny; pathogenicity; peroxidases; phenolic compounds; ripening; winter barley
Abstract:
... The occurrence and epidemic spread of ramularia leaf spot (RLS) caused by Ramularia collo-cygni was studied with relation to the plant age-dependent alterations in the antioxidative defence systems in the leaves during mature stages of field-grown winter barley. The breakdown of enzymatic activities of dehydroascorbate reductase, monodehydroascorbate reductase and glutathione reductase in the two ...
DOI:
10.1111/j.1365-3059.2007.01820.x

20. Airborne based spectroscopy of red and far-red sun-induced chlorophyll fluorescence: Implications for improved estimates of gross primary productivity

Author:
Stadler, A.,   et al.   ; Wieneke, S.; Ahrends, H.; Damm, A.; Pinto, F.; Rossini, M.; Rascher, U.;     Show all 7 Authors
Source:
Remote sensing of environment 2016 v.184 pp. 654-667
ISSN:
0034-4257
Subject:
chlorophyll; fluorescence; image analysis; models; photosynthesis; plant adaptation; plant stress; primary productivity; reflectance; remote sensing; spectrometers; spectroscopy; vegetation; vegetation index; water shortages
Abstract:
... Remote sensing (RS) approaches commonly applied to constrain estimates of gross primary production (GPP) employ greenness-based vegetation indices derived from surface reflectance data. Such approaches cannot capture dynamic changes of photosynthesis rates as caused by environmental stress. Further, applied vegetation indices are often affected by background reflectance or saturation effects. Sun. ...
DOI:
10.1016/j.rse.2016.07.025