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- Ahmad, Md Fahim, et al. Show all 5 Authors
- International journal of biological macromolecules 2019 v.125 pp. 469-477
- affinity chromatography; amyloid; antibodies; antibody formation; antigens; antiserum; dimerization; dissociation; fluorescence; gel chromatography; immunoglobulin G; ion exchange; pH; precision medicine; spectral analysis; sulfides
- ... Bispecific antibodies (BsAbs), are potential theranostics. Chemical procedures of preparation of BsAbs, in which two monospecific antibodies are split into half molecules and heterodimerized, continue to attract attention in view of their simplicity. Poor dissociation of antibodies with reduced inter-heavy chain disulfides into half molecules under neutral conditions however restricts the BsAbs fo ...