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- Arcelik, Nejat, et al. Show all 6 Authors
- Tetrahedron letters 2019 v.60 no.3 pp. 284-287
- acid hydrolysis; amino acids; beta-lactams; crystallization; enantiomers; ethyleneimine; moieties
- ... Enantiopure β-aminocyclooctenenitriles, as precursors of β-amino acids and β-lactams, were synthesized from a readily available chloroalkene nitrile and (S)-methylbenzylamine via a straightforward substitution reaction and purified by crystallization. Acidic hydrolysis of the nitrile groups to their corresponding amides followed by DCC assisted carbonyl group activation gave novel α,β-unsaturated ...