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- Atsumi, Toru, et al. Show all 19 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2014 v.111 no.32 pp. 11786-11791
- B-lymphocytes; antigens; crosslinking; homeostasis; humoral immunity; immune response; immunosuppression (physiological); signal transduction; zinc
- ... The humoral immune response, also called the antibody-mediated immune response, is one of the main adaptive immune systems. The essential micronutrient zinc (Zn) is known to modulate adaptive immune responses, and dysregulated Zn homeostasis leads to immunodeficiency. However, the molecular mechanisms underlying this Zn-mediated modulation are largely unknown. Here, we show that the Zn transporter ...
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