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1. First description of natural concomitant infection of avian nephritis virus and infectious bronchitis virus reveals exacerbated inflammatory response and renal damage in broiler chicks

Author:
Munuswamy, Palanivelu; Ramakrishnan, Saravanan; Latheef, Shyma K.; Kappala, Deepthi; Mariappan, Asok Kumar; Kaore, Megha; Anbazhagan, Karthikeyan; Puvvala, Bhavani; Singh, Karam Pal; Dhama, Kuldeep
Source:
Microbial pathogenesis 2021 v.154 pp. 104830
ISSN:
0882-4010
Subject:
Avian nephritis virus,   etc   ; ; Avastrovirus 2; Infectious bronchitis virus; RNA-directed RNA polymerase; genes; glycoproteins; histopathology; inflammation; interleukin-12; interleukin-13; interleukin-4; macrophages; mixed infection; necropsy; pathogenesis; viruses;     Show all 17 Subjects
Abstract:
... We describe the first report on spontaneous Avian Nephritis Virus (ANV) and Infectious Bronchitis Virus (IBV) concurrent infection in broiler chicks. On necropsy, the kidneys were found swollen with its parenchyma and ureters stuffed with urate flakes. Histopathologically, the renal tubular damage and inflammatory response were severe in concurrently infected birds compared to the cases infected o ...
DOI:
10.1016/j.micpath.2021.104830

2. Molecular characterization of chicken astroviruses in gout-affected commercial broiler chickens in Haryana, India

Author:
Panigrahi, Sumitra; Jindal, Naresh; Kumar, Pawan; Barua, Sanjay; Kumar, Naveen; Riyesh, Thachamvally; Chander, Yogesh
Source:
Virusdisease 2019 v.30 no.4 pp. 551-561
ISSN:
2347-3584
Subject:
Avian nephritis virus,   etc   ; broiler chickens; capsid; chicken eggs; chicks; embryo (animal); flocks; gastroenteritis; genes; gout; kidneys; liver; necrosis; phylogeny; reverse transcriptase polymerase chain reaction; serotypes; specific pathogen-free animals; viruses; India;     Show all 19 Subjects
Abstract:
... Chicken astroviruses (CAstVs) infect young chicks and are associated with gastroenteritis, stunted growth or visceral gout (gout). True incidence and distribution of CAstVs as well as virus variants circulating in India is not well understood. In this study, 80 gout-affected broiler chicken flocks from Haryana, a north-western state of India, were tested for the presence of astroviruses by targeti ...
DOI:
10.1007/s13337-019-00554-1
PubMed:
31897418
PubMed Central:
PMC6917690

3. Avian nephritis virus (ANV) on Brazilian chickens farms: circulating genotypes and intra-genotypic diversity

Author:
Espinoza, Luis Luna; Beserra, Laila A. R.; Soares, Rodrigo M.; Gregori, Fabio
Source:
Archives of virology 2016 v.161 no.12 pp. 3455-3462
ISSN:
0304-8608
Subject:
Avian nephritis virus,   etc   ; amino acid sequences; chickens; clones; farms; feces; flocks; genes; genetic variation; genotype; mixed infection; phylogeny; polymerase chain reaction; poultry industry; viruses; Brazil;     Show all 16 Subjects
Abstract:
... Avian nephritis virus (ANV), which belongs to the family Astroviridae, is associated with different clinical manifestations (including enteric disorders). Despite being frequently found in the avian industry worldwide, information regarding genetic features of these viruses in Brazil is scarce. Therefore, sixty fecal sample pools (5-6 birds of the same flock), representing 60 poultry farms from si ...
DOI:
10.1007/s00705-016-3057-7

4. Prevalence of histopathological intestinal lesions and enteric pathogens in Dutch commercial broilers with time

Author:
ter Veen, C.; de Bruijn, N. D.; Dijkman, R.; de Wit, J. J.
Source:
Avian pathology 2017 v.46 no.1 pp. 95-105
ISSN:
1465-3338
Subject:
Avian nephritis virus,   etc   ; Chicken astrovirus; Eimeria acervulina; Rotavirus A; Rotavirus D; birds; coccidiosis; coccidiostats; enteritis; enteropathogens; farms; flocks; histopathology; industry; jejunum; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; viruses;     Show all 18 Subjects
Abstract:
... Intestinal disease has a major impact on the broiler industry due to economic and welfare reasons. Intestinal disease might occur due to a large number of reasons varying from well-defined pathogens to non-specific enteritis and complex syndromes. However, knowledge about the nature of intestinal disease and presence of enteric viruses in the Dutch broiler industry is largely absent. Therefore, a ...
DOI:
10.1080/03079457.2016.1223271

5. Pathogenesis of Renal Lesions in Chickens After Experimental Infection With 9a5b Newcastle Disease Virus Mutant Isolate

Author:
El-Bahrawy, A.; Zaid, A.; Sunden, Y.; Sakurai, M.; Ito, H.; Ito, T.; Morita, T.
ISSN:
1544-2217
Subject:
Avian nephritis virus,   etc   ; chickens; animal pathology; cortex; specific pathogen-free animals; immunohistochemistry; Influenza A virus; reverse transcriptase polymerase chain reaction; Avian orthoavulavirus 1; pathogenesis; Infectious bronchitis virus; mutants; kidneys; nephritis; titration; histopathology;     Show all 16 Subjects
Abstract:
... In this study, we investigated the pathogenesis of Newcastle disease virus (NDV) in the chicken kidney. Twenty-six 32-day-old specific pathogen-free chickens were intranasally inoculated with the 9a5b NDV mutant isolate. Kidney tissue samples, collected at 6 and 12 hours postinoculation (hpi) and 1, 2, 3, 5, and 10 days postinoculation (dpi), were analyzed by histopathology, immunohistochemistry ( ...
DOI:
10.1177/0300985816655852

6. Sensitive SYBR Green—Real Time PCR for the Detection and Quantitation of Avian Rotavirus A

Author:
De la Torre, David; Astolfi-Ferreira, Claudete S.; Chacon, Ruy D.; Piantino Ferreira, Antonio J.
Source:
Veterinary sciences 2018 v.6 no.1
ISSN:
2306-7381
Subject:
Avian nephritis virus,   etc   ; Chicken astrovirus; Galliform aveparvovirus 1; Infectious bronchitis virus; Rotavirus A; animal viruses; birds; cell culture; complementary DNA; detection limit; diarrhea; electron microscopy; financial economics; genes; green chemistry; infectious bursal disease; mixed infection; nucleotide sequences; poultry industry; quantitative polymerase chain reaction; rapid methods; reverse transcriptase polymerase chain reaction; serology; tissues; vaccines; viruses;     Show all 26 Subjects
Abstract:
... Avian rotavirus A (ARtV-A) is a virus that affects young birds, causing acute diarrhea and economic losses in the poultry industry worldwide. The techniques used for the diagnosis of ARtV-A include electron microscopy, isolation in cell culture, and serology, as well as molecular techniques, such as the reverse transcription-polymerase chain reaction (RT-PCR). The objective of this work was to sta ...
DOI:
10.3390/vetsci6010002
PubMed:
30597964
PubMed Central:
PMC6466117

7. Isolation of avian nephritis virus from chickens showing enteric disorders

Author:
Nuñez, Luis Fabian N; Parra, Silvana H Santander; De la Torre, David; Catroxo, Marcia H; Buim, Marcos R; Chacon, Ruy V; Ferreira, Claudete S Astolfi; Piantino Ferreira, Antonio J
Source:
Poultry science 2018 v.97 no.10 pp. 3478-3488
ISSN:
0032-5791
Subject:
Avian nephritis virus,   etc   ; RNA; amino acids; chickens; complementary DNA; digestive system diseases; disease outbreaks; dwarfing; edema; eggs; electron microscopy; etiological agents; genes; hemorrhage; open reading frames; phylogeny; reverse transcriptase polymerase chain reaction; serotypes; specific pathogen-free animals; virion; viruses; yolk sac; Australia; Brazil; China; Japan; United States;     Show all 27 Subjects
Abstract:
... Runting-stunting syndrome (RSS) is one of the diseases associated with many detected viruses. In Brazil, there were reports of several enteric disease outbreaks in chickens in which avian nephritis virus (ANV) was detected; however, the role of ANV in the outbreaks and whether the virus was a causative agent of these cases of enteric diseases were not determined. The aim of this study was to isola ...
DOI:
10.3382/ps/pey207
PubMed:
30239960
PubMed Central:
PMC6142861

8. The C-terminal end of the capsid protein of Avian Nephritis Virus is antigenic and induces broadly cross-reactive antibodies

Author:
Hewson, K.A.; Wawegama, N.K.; O’Rourke, D.; Putri, K.; Chamings, A.; Noormohammadi, A.H.; Ignjatovic, J.
Source:
Journal of virological methods 2015 v.221 pp. 106-114
ISSN:
0166-0934
Subject:
Avian nephritis virus,   etc   ; Baculoviridae; Human astrovirus; antibodies; antigens; blood serum; chickens; coat proteins; crystal structure; economic impact; enzyme-linked immunosorbent assay; epidemiology; flocks; models; protein synthesis; recombinant proteins;     Show all 16 Subjects
Abstract:
... Avian nephritis virus (ANV) has been isolated frequently from commercial broilers in many countries. The prevalence and economic impact of ANV however has been difficult to ascertain due to the lack of convenient serological techniques. In this study the full-length and fragments of the ANV capsid protein were expressed in Baculovirus and affinity purified recombinant proteins used for the detecti ...
DOI:
10.1016/j.jviromet.2015.04.019

9. A metagenomic comparison of endemic viruses from broiler chickens with runting-stunting syndrome and from normal birds

Author:
Devaney, Ryan; Trudgett, James; Trudgett, Alan; Meharg, Caroline; Smyth, Victoria
Source:
Avian pathology 2016 v.45 no.6 pp. 616-629
ISSN:
1465-3338
Subject:
Avian nephritis virus,   etc   ; Chicken astrovirus; Chicken calicivirus; Coronaviridae; DNA; Galliform aveparvovirus 1; Myoviridae; Picornaviridae; RNA; Siphoviridae; body weight; broiler chickens; digestive system; feed conversion; high-throughput nucleotide sequencing; metagenomics; pathogens; viruses;     Show all 18 Subjects
Abstract:
... Runting-stunting syndrome (RSS) in broiler chickens is an enteric disease that causes significant economic losses to poultry producers worldwide due to elevated feed conversion ratios, decreased body weight during growth, and excessive culling. Of specific interest are the viral agents associated with RSS which have been difficult to fully characterize to date. Past research into the aetiology of ...
DOI:
10.1080/03079457.2016.1193123
PubMed:
27215546
PubMed Central:
PMC7113909

10. Detection and molecular characterization of astroviruses in turkeys

Author:
Singh, Azad; Mor, Sunil K.; Jindal, Naresh; Patnayak, Devi; Sobhy, Nader M.; Luong, Nhungoc Ti; Goyal, Sagar M.
Source:
Archives of virology 2016 v.161 no.4 pp. 939-946
ISSN:
0304-8608
Subject:
Avian nephritis virus,   etc   ; Avastrovirus 1; Turkey astrovirus; amino acid substitution; body weight; chickens; enteritis; feces; flocks; genes; nucleotide sequences; pathogenesis; pathogens; phylogeny; poults; screening; sequence analysis; turkeys; viruses; Minnesota;     Show all 20 Subjects
Abstract:
... This study was conducted to determine the prevalence and molecular characteristics of turkey astrovirus 1 (TAstV-1) and avian nephritis virus (ANV) in turkeys with light turkey syndrome (LTS), which is characterized by lower body weight in market-age turkeys than their standard breed character. We collected pools of fecal samples from four LTS and two non-LTS turkey flocks in Minnesota at 2, 3, 5 ...
DOI:
10.1007/s00705-016-2753-7

11. Astroviruses in Polish Commercial Turkey Farms in 2009–2012

Author:
Domańska-Blicharz, Katarzyna; Jacukowicz, Anna; Bocian, Lukasz; Minta, Zenon
Source:
Avian diseases 2014 v.58 no.1 pp. 158-164
ISSN:
1938-4351
Subject:
Avian nephritis virus,   etc   ; enteritis; farms; feces; flocks; genetic variation; health status; mortality; nucleotide sequences; phylogeny; poultry diseases; statistical analysis; turkeys; Poland;     Show all 14 Subjects
Abstract:
... Avian astrovirus infections are widespread in many countries, and infections have been connected with enteritis and increased mortality in young birds. In the present study, fecal samples were collected during 2009–2012 from a total of 156 meat turkey flocks. Astrovirus presence and type differentiation was performed with the use of two molecular diagnostic approaches. Out of 156 flocks, 48.7% wer ...
DOI:
10.1637/10611-070813-ResNote.1

12. High-resolution melt curve analysis to confirm the presence of co-circulating isolates of avian nephritis virus in commercial chicken flocks

Author:
Chamings, A.; Hewson, K. A.; O'Rourke, D.; Ignjatovic, J.; Noormohammadi, A. H.
Source:
Avian pathology 2015 v.44 no.6 pp. 443-451
ISSN:
1465-3338
Subject:
Avian nephritis virus,   etc   ; amino acid sequences; ancestry; broiler chickens; capsid; cloaca; epidemiological studies; flocks; genes; kidney diseases; meat; melting; molecular cloning; nucleotide sequences; phylogeny; reverse transcriptase polymerase chain reaction; sequence analysis; viruses;     Show all 18 Subjects
Abstract:
... Avian Nephritis Virus (ANV) has been implicated in poor growth and renal disease of young chickens. This paper describes the development of a reverse-transcriptase polymerase chain reaction for the detection of ANV in commercial meat chickens and the use of high-resolution melt curves to detect the presence of genetically different ANVs. Pooled cloacal swabs from both healthy and ill commercial ch ...
DOI:
10.1080/03079457.2015.1085648

13. Complete sequence and genetic characterization of pigeon avian nephritis virus, a member of the family Astroviridae

Author:
Zhao, W.; Zhu, A. L.; Yu, Y.; Yuan, C. L.; Zhu, C. X.; Yang, Z. B.; Cui, L.; Hua, X. G.
Source:
Archives of virology 2011 v.156 no.9 pp. 1559-1565
ISSN:
0304-8608
Subject:
Avian nephritis virus,   etc   ; amino acid sequences; chickens; coat proteins; genes; nucleotides; open reading frames; phylogeny; pigeons; viruses;     Show all 10 Subjects
Abstract:
... In the current study, the complete genome sequence of a member of the family Astroviridae isolated from pigeons was determined through genetic characterization and phylogeny analysis. The isolated genome sequence was proposed to be that of pigeon avian nephritis virus (ANV), whose genome structure and characteristics were similar to previously reported avian astroviruses. The sequenced ssRNA genom ...
DOI:
10.1007/s00705-011-1034-8
PubMed:
21618030

14. Simultaneous detection of astrovirus, rotavirus, reovirus and adenovirus type I in broiler chicken flocks

Author:
Roussan, D.; Shaheen, I.; Khawaldeh, G.; Totanji, W.; Al-Rifai, R.
Source:
Polish journal of veterinary sciences 2012 v.15 no.2 pp. 337-344
ISSN:
1505-1773
Subject:
Avian nephritis virus,   etc   ; Adenoviridae; Chicken astrovirus; Rotavirus; broiler chickens; digestive system diseases; flocks; mixed infection; pathogenesis; pathogens; poultry industry; reverse transcriptase polymerase chain reaction; transcription (genetics); viruses;     Show all 14 Subjects
Abstract:
... Enteric diseases cause substantial economic losses to the poultry industry. Astroviruses, rotaviruses, reoviruses, and adenovirus type 1 have been reported as a significant cause of intestinal symptoms in poultry. In the present study, intestinal samples from 70 commercial broiler chicken flocks were examined for the presence of astroviruses, rotavirus, and reovirus by reverse transcription-polyme ...
DOI:
10.2478/v10181-012-0052-0

15. Investigation into the aetiology of runting and stunting syndrome in chickens

Author:
Kang, Kyung-Il; El-Gazzar, Mohamed; Sellers, Holly S.; Dorea, Fernanda; Williams, Susan M.; Kim, Taejoong; Collett, Stephen; Mundt, Egbert
Source:
Avian pathology 2012 v.41 no.1 pp. 41-50
ISSN:
1465-3338
Subject:
Avian nephritis virus,   etc   ; chickens; bursa of Fabricius; duodenum; Chicken astrovirus; etiology; in situ hybridization; weight gain; Galliform aveparvovirus 1; growth retardation; RNA;     Show all 11 Subjects
Abstract:
... Currently, the aetiology of runting and stunting syndrome (RSS) in chickens is unknown. The impact of RSS on weight gain and microscopic lesions in immunological organs and the duodenum, was investigated in 1-day-old commercial broilers at 12 days following exposure to RSS-contaminated litter. Furthermore, the presence of the viral nucleic acids of three astroviruses and one parvovirus was analyse ...
DOI:
10.1080/03079457.2011.632402

16. Viral agents related to enteric disease in commercial chicken flocks, with special reference to Latin America

Author:
NUÑEZ, L.F.N.; PIANTINO FERREIRA, A.J.
Source:
World's poultry science journal 2013 v.69 no.4 pp. 853-864
ISSN:
1743-4777
Subject:
Avian nephritis virus,   etc   ; Chicken astrovirus; Galliform aveparvovirus 1; Infectious bronchitis virus; Rotavirus; body weight changes; chickens; diarrhea; economic impact; etiology; flocks; food consumption; mortality; poultry diseases; turkeys; viruses; Latin America;     Show all 17 Subjects
Abstract:
... Poultry enteric diseases are an important economic problem involving many etiologic agents, including enteric viruses. Several viral agents have been detected around the world in enteric contents isolated from commercial chicken and turkeys flocks that initially appear healthy but exhibit enteric signs, such as diarrhoea, decreased food consumption, loss of body weight, and mortality. Chicken astr ...
DOI:
10.1017/S0043933913000858

17. Capsid protein sequence diversity of avian nephritis virus

Author:
Todd, D.; Trudgett, J.; Smyth, V. J.; Donnelly, B.; McBride, N.; Welsh, M. D.
Source:
Avian pathology 2011 v.40 no.3 pp. 249-259
ISSN:
1465-3338
Subject:
Avian nephritis virus,   etc   ; RNA; amino acids; birds; capsid; coat proteins; flocks; nephritis; nucleotide sequences; phylogeny; serotypes; viruses; Belgium; Germany; United Kingdom;     Show all 15 Subjects
Abstract:
... The capsid gene sequences of 25 avian nephritis viruses (ANVs), collected in the UK, Germany and Belgium from the 1980s to 2008, were determined and compared with those of serotype 1 (ANV-1) and serotype 2 (ANV-2) ANV isolates. Amino acid identities as low as 51% were determined. Pairwise comparisons supported by phylogenetic analysis identified six ANVs, including ANV-1 and ANV-2, which shared<80 ...
DOI:
10.1080/03079457.2011.553583

18. Molecular characterization of avian astroviruses

Author:
Pantin-Jackwood, M. J.; Strother, K. O.; Mundt, E.; Zsak, L.; Day, J. M.; Spackman, E.
Source:
Archives of virology 2011 v.156 no.2 pp. 235-244
ISSN:
0304-8608
Subject:
Avian nephritis virus,   etc   ; Chicken astrovirus; Duck astrovirus; amino acid sequences; broiler chickens; enteritis; genetic variation; poultry diseases; poults; sequence analysis; serotypes; turkeys;     Show all 12 Subjects
Abstract:
... Astroviruses are frequently associated with enteric diseases in poultry, being isolated from cases of runting-stunting syndrome (RSS) of broiler chickens, poult enteritis complex (PEC), and poult enteritis mortality syndrome (PEMS) of turkeys. Currently, five types of avian astrovirus have been identified: turkey astroviruses 1 and 2 (TAstV-1, TAstV-2), avian nephritis virus (ANV), chicken astrovi ...
DOI:
10.1007/s00705-010-0849-z
PubMed:
21069394

19. Detection of Avian Nephritis Virus in Australian Chicken Flocks

Author:
Hewson, Kylie A.; O'Rourke, Denise; Noormohammadi, Amir H.
Source:
Avian diseases 2010 v.54 no.3 pp. 990-993
ISSN:
0005-2086
Subject:
Avian nephritis virus,   etc   ; broiler chickens; poultry diseases; disease detection; histopathology; polymerase chain reaction; gene banks; microbial detection; pathogen identification; microbial genetics; nucleotide sequences; Australia;     Show all 12 Subjects
Abstract:
... Avian nephritis virus (ANV) is thought to infect poultry flocks worldwide, but no confirmed case has been reported in Australia. The first such case is described in this study. Cases of young chickens with clinical signs of dehydration and diarrhea were submitted to our laboratory and histopathology detected interstitial nephritis. Vaccine strains of infectious bronchitis virus were detected in so ...
DOI:
10.1637/9230-010610-Reg.1
PubMed:
20945778

20. Development and evaluation of real-time TaqMan® RT-PCR assays for the detection of avian nephritis virus and chicken astrovirus in chickens

Author:
Smyth, V.J.; Jewhurst, H.L.; Wilkinson, D.S.; Adair, B.M.; Gordon, A.W.; Todd, D.
Source:
Avian pathology 2010 v.39 no.6 pp. 467-474
ISSN:
0307-9457
Subject:
Avian nephritis virus,   etc   ; 3' untranslated regions; Chicken astrovirus; broiler chickens; digestive system; flocks; genome; growth performance; inoculum; kidneys; open reading frames; reverse transcriptase polymerase chain reaction; surveys; viruses;     Show all 14 Subjects
Abstract:
... The development and preliminary evaluations of two TaqMan®-based, real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) assays for the quantitative detection of avian nephritis virus (ANV) and chicken astrovirus (CAstV) RNAs are described. The assays used amplicons generated from the 3' untranslated region of the ANV genome and a conserved region of CAstV open reading frame 1b includ ...
DOI:
10.1080/03079457.2010.516387