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1. Effects of heat stress on the immune responses of chickens subjected to thermal manipulation in the pre-hatch period

Author:
Kőrösi Molnár, Andrea; Kőrösi, László; Balázs, Bence; Gáspárdy, András
Source:
Acta veterinaria Hungarica 2021 v.69 no.1 pp. 67-72
ISSN:
1588-2705
Subject:
Avian orthoavulavirus 1,   etc   ; antibodies; antibody formation; heat; heat stress; heterophils; immunosuppression; stress tolerance; vaccination;     Show all 9 Subjects
Abstract:
... Heat stress affects the performance of poultry species and also induces immunosuppression. Chickens can be treated by thermal conditioning to have better heat stress tolerance. Our purpose was to determine the effect of acute heat stress on the immune response, i.e. antibody production against Newcastle disease virus (NDV) and change in the proportion of leukocyte components, in chicks subjected t ...
DOI:
10.1556/004.2021.00003

2. Rapid Generation of a Recombinant Genotype VIII Newcastle Disease Virus (NDV) Using Full-Length Synthetic cDNA

Author:
Murulitharan, Kavitha; Yusoff, Khatijah; Omar, Abdul Rahman; Peeters, Ben P. H.; Molouki, Aidin
Source:
Current microbiology 2021 v.78 no.4 pp. 1458-1465
ISSN:
0343-8651
Subject:
Avian orthoavulavirus 1,   etc   ; death; digestion; genotype; mutation; plasmids; transcription initiation site; transfection; virulence; viruses;     Show all 10 Subjects
Abstract:
... Rescue of (−)ssRNA viruses involves the sequential assembly and cloning of the full-length cDNA, which is often a challenging and time-consuming process. The objective of this study was to develop a novel method to rapidly clone the full-length cDNA of a very virulent NDV by only one assembly step. A completely synthetic 15 kb cDNA of a Malaysian genotype VIII NDV known as strain AF2240-I with add ...
DOI:
10.1007/s00284-021-02421-z

3. Activation of the extracellular signal-regulated kinase pathway is required for replication of Newcastle disease virus

Author:
Ni, Jie; Hu, Shunlin; Wang, Xiaoquan; Liu, Xiaowen; Hu, Zenglei; Liu, Xiufan
Source:
Archives of virology 2021 v.166 no.3 pp. 921-927
ISSN:
0304-8608
Subject:
Avian orthoavulavirus 1,   etc   ; chick embryos; cytopathogenicity; fibroblasts; mitogen-activated protein kinase; virus replication;     Show all 6 Subjects
Abstract:
... Replication of Newcastle disease virus (NDV) is regulated by various host mechanisms, but the role of the extracellular signal-regulated kinase (ERK) pathway in regulating NDV replication is an open question. In this study, the relationship between the ERK pathway and NDV replication was investigated. NDV activated the ERK signaling in chicken embryo fibroblasts at the late stage of infection, cor ...
DOI:
10.1007/s00705-020-04938-3

4. Co-circulation of genotypes XIV.2 and XVIII.2 of avian paramyxovirus-1 (Newcastle disease virus) in backyard poultry in Niger

Author:
Souley, Maman Moutari; Issa Ibrahim, Abdoulkarim; Souley Kouato, Bachir; Abdou, Alassane; Issa, Rahila; Yaou, Bachir; Amadou, Hadiza; Hama, Hama; Adakal, Hassane; Abdou, Nourou; Cattoli, Giovanni; Dundon, William G.
Source:
Virus genes 2021 v.57 no.1 pp. 100-105
ISSN:
0920-8569
Subject:
Avian orthoavulavirus 1,   etc   ; Newcastle disease; economic impact; etiological agents; genes; genotype; phylogeny; poultry production; viruses; Niger;     Show all 10 Subjects
Abstract:
... The causative agent of Newcastle disease (ND) of poultry is the avian paramyxovirus-1, also commonly known as ND virus (NDV). Like in many developing countries, ND is endemic in Niger and has significant economic impact on commercial and backyard poultry production. NDVs were characterized in Niger between 2006 and 2008 and shown to belong to genotypes XIV.1 and XVII. In order to determine the cur ...
DOI:
10.1007/s11262-020-01804-x

5. Comparative biology of two genetically closely related Newcastle disease virus strains with strongly contrasting pathogenicity

Author:
Chen, Xi; Chen, Siqi; Chen, Haotian; Tian, Jianxia; Zhao, Xueliang; Jia, Yanqing; Xiao, Sa; Wang, Xinglong; Liu, Haijin; Yang, Zengqi
Source:
Veterinary microbiology 2021 v.253 pp. 108977
ISSN:
0378-1135
Subject:
Avian orthoavulavirus 1,   etc   ; amino acids; membrane fusion; mortality; nucleoproteins; viral genome; virulence;     Show all 7 Subjects
Abstract:
... A lentogenic strain of Newcastle disease virus (NDV) with an intracerebral pathogenicity index (ICPI) of 0.36 was derived by the passage of a mesogenic NDV isolate with an original ICPI of 1.04. Animal experiments showed that the original strain caused much severer clinical signs and mortality than the derived strain in chickens. To elucidate the molecular reason for this virulence change, the com ...
DOI:
10.1016/j.vetmic.2020.108977

6. Comparison of three filter paper-based devices for safety and stability of viral sample collection in poultry

Author:
Wannaratana, Suwarak; Thontiravong, Aunyaratana; Pakpinyo, Somsak
Source:
Avian pathology 2021 v.50 no.1 pp. 78-84
ISSN:
1465-3338
Subject:
Avian orthoavulavirus 1,   etc   ; DNA; birds; blood; detection limit; live vaccines; paper; poultry; poultry industry; transportation; viruses;     Show all 11 Subjects
Abstract:
... General diagnosis of poultry viruses primarily relies on detection of viruses in samples, but many farms are located in remote areas requiring logistic transportation. Filter paper cards are a useful technology that offer an alternative for collecting and preserving samples without hazardous exposure. The goal of this study was to compare three filter papers: the Flinders Technology Associates fil ...
DOI:
10.1080/03079457.2020.1837343

7. A bibliometric review of oncolytic virus research as a novel approach for cancer therapy

Author:
Mozaffari Nejad, Amir Sasan; Noor, Tehjeeb; Munim, Ziaul Haque; Alikhani, Mohammad Yousef; Ghaemi, Amir
Source:
Virology journal 2021 v.18 no.1 pp. 98
ISSN:
1743-422X
Subject:
Avian orthoavulavirus 1,   etc   ; Adenoviridae; Reoviridae; antineoplastic activity; biomedical research; cancer therapy; databases; herpes simplex; systematic review; virology; viruses; Canada; Finland;     Show all 13 Subjects
Abstract:
... BACKGROUND: In recent years, oncolytic viruses (OVs) have drawn attention as a novel therapy to various types of cancers, both in clinical and preclinical cancer studies all around the world. Consequently, researchers have been actively working on enhancing cancer therapy since the early twentieth century. This study presents a systematic review of the literature on OVs, discusses underlying resea ...
DOI:
10.1186/s12985-021-01571-7

8. Identification of a potential neutralizing linear epitope of hemagglutinin-neuraminidase in Newcastle disease virus

Author:
Jin, Zhongyuan; Wei, Qiaolin; Bi, Youkun; Li, Yongshan; Huo, Na; Mou, Sujing; Wang, Wenbin; Liu, Haijin; Yang, Zengqi; Chen, Hongjun; Xiao, Sa
Source:
Virology journal 2021 v.18 no.1 pp. 8
ISSN:
1743-422X
Subject:
Avian orthoavulavirus 1,   etc   ; B-lymphocytes; chickens; fluorescent antibody technique; immunodominant epitopes; immunogenicity; mice; neutralization tests; peptides; plasmids; vaccines; virology; virulence;     Show all 13 Subjects
Abstract:
... BACKGROUND: The hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is a major antigen that can induce protective antibodies in poultry. However, its antigenic epitopes have not been fully elucidated. Therefore, defining the linear epitopes of HN, especially neutralizing epitopes, will be useful for revealing its antigenic characterization. METHODS: In this study, we analyzed ...
DOI:
10.1186/s12985-020-01483-y

9. Comparison of the protective antigen variabilities of prevalent Newcastle disease viruses in response to homologous/heterologous genotype vaccines

Author:
Li, Yonghua; Rehman, Zaib Ur; Li, Mengjiao; Manzoor, Zahid; Liu, Wei; Qiu, Xusheng; Sun, Yingjie; Liao, Ying; Tan, Lei; Song, Cuiping; Liu, Weiwei; Yu, Shengqing; Ding, Chan; Meng, Chunchun
Source:
Poultry science 2021 v.100 no.8 pp. 101267
ISSN:
0032-5791
Subject:
Avian orthoavulavirus 1,   etc   ; Newcastle disease; antigens; blood serum; chickens; genes; genotype; mutation; selection pressure; viruses; waterfowl; China;     Show all 12 Subjects
Abstract:
... The genotype VII Newcastle disease virus (NDV) vaccine has begun to replace the traditional genotype II NDV vaccine and is widely used in the commercial poultry of China. However, the effect of homologous and heterogeneous anti-NDV serum on the evolution of prevalent NDV is unknown. To understand the effect of genotype II and VII anti-NDV serum on the evolution of genotype VII NDV strains, ZJ1 (wa ...
DOI:
10.1016/j.psj.2021.101267

10. Musashi1 inhibit the release of Newcastle disease viruses through preventing apoptosis of DF-1 cells

Author:
Yang, Mengqing; Ma, Jiangang; Chu, Zhili; Cao, Xuhong; Lu, Kejia; Shi, Xiaolei; Tong, Lina; Yan, Chuanqi; Liu, Haijin; Wang, Xinglong; Xiao, Sa; Yang, Zengqi
Source:
Poultry science 2021 v.100 no.7 pp. 101105
ISSN:
0032-5791
Subject:
Avian orthoavulavirus 1,   etc   ; Newcastle disease; apoptosis; flow cytometry; innate immunity; precipitin tests; transfection; viral nonstructural proteins; virus replication; viruses;     Show all 10 Subjects
Abstract:
... The efficient proliferation of Newcastle disease virus (NDV) depends on its inhibition of host cell innate immunity. V protein acts as a nonstructural protein which plays a significant role in virus replication, whereas its function remains to be further explored. In this study, Musashi RNA binding protein 1 (MSI1) was selected and its interaction with V protein was further verified by Co-immunopr ...
DOI:
10.1016/j.psj.2021.101105

11. Pekin duck productivity, physiological stress, immune response and behavior under 20L:4D and 16L:8D photoperiods

Author:
House, G.M.; Sobotik, E.B.; Nelson, J.R.; Archer, G.S.
Source:
Applied animal behaviour science 2021 v.240 pp. 105351
ISSN:
0168-1591
Subject:
Avian orthoavulavirus 1,   etc   ; Pekin; asymmetry; corticosterone; ducks; fearfulness; feed conversion; heterophils; humoral immunity; immune response; metabolism; photoperiod; vaccines;     Show all 13 Subjects
Abstract:
... As duck production becomes more prevalent on a global scale, modern duck housing systems must utilize artificial lighting photoperiods to maximize production and welfare; however, limited research has examined the manipulation of photoperiods on Pekin ducks. The objective of this study was therefore to determine the effects of two photoperiods – 20 h of light (L): 4 h of darkness (D) and 16 L:8D - ...
DOI:
10.1016/j.applanim.2021.105351

12. Development of a TaqMan loop-mediated isothermal amplification assay for the rapid detection of pigeon paramyxovirus type 1

Author:
Liang, Ruiying; Liang, Lin; Ren, Xiaoxia; Jia, Yaxiong; Han, Kun; Zhao, Jingjie; Song, Cuiping; Cui, Shangjin
Source:
Archives of virology 2021 v.166 no.6 pp. 1599-1605
ISSN:
0304-8608
Subject:
Avian orthoavulavirus 1,   etc   ; RNA; detection limit; genes; loop-mediated isothermal amplification; pigeons; poultry industry; rapid methods; vaccines; virology;     Show all 10 Subjects
Abstract:
... Pigeon paramyxovirus-1 (PPMV-1) is a strain of Newcastle disease virus (NDV) that has adapted to infect pigeons and poses a constant threat to the commercial poultry industry. Early detection via rapid and sensitive methods, along with timely preventative and mitigating actions, is important for reducing the spread of PPMV-1. Here, we report the development of a TaqMan loop-mediated isothermal amp ...
DOI:
10.1007/s00705-021-04963-w

13. The chicken-derived velogenic Newcastle disease virus can acquire high pathogenicity in domestic ducks via serial passaging

Author:
Hidaka, Chiharu; Soda, Kosuke; Nomura, Fumie; Kashiwabara, Yukie; Ito, Hiroshi; Ito, Toshihiro
Source:
Avian pathology 2021 v.50 no.3 pp. 234-245
ISSN:
1465-3338
Subject:
Avian orthoavulavirus 1,   etc   ; ; Newcastle disease; air; amino acids; disease severity; ducks; fibroblasts; gene expression; mortality; virulence; viruses; waterfowl;     Show all 13 Subjects
Abstract:
... Velogenic Newcastle disease virus (NDV) strains, which show high mortality in chickens, generally do not cause severe disease in waterfowl such as ducks. To elucidate the difference in the pathogenic mechanisms of NDV between chickens and ducks, a chicken-derived velogenic strain (9a5b) was passaged in domestic ducks five times in their air sacs, followed by 20 times in their brains. Eventually, 9 ...
DOI:
10.1080/03079457.2021.1889461

14. Development of a T7 RNA polymerase expressing cell line using lentivirus vectors for the recovery of recombinant Newcastle disease virus

Author:
Yeong, Ming Yue; Cheow, Pheik-Sheen; Abdullah, Syahril; Song, Adelene Ai-Lian; Lei-Rossmann, Janet; Tan, Tiong-Kit; Yusoff, Khatijah; Chia, Suet-Lin
Source:
Journal of virological methods 2021 v.291 pp. 114099
ISSN:
0166-0934
Subject:
Avian orthoavulavirus 1,   etc   ; DNA-directed RNA polymerase; cell lines; gene expression; genes; plasmids; reverse genetics; transfection; virology; viruses;     Show all 10 Subjects
Abstract:
... The development of a T7 RNA polymerase (T7 RNAP) expressing cell line i.e. BSR T7/5 cells marks an improvement of reverse genetics for the recovery of recombinant Newcastle disease virus (rNDV). BSR T7/5 is developed by transient transfection of plasmid encoding T7 RNAP gene for rNDV rescue. However, the gene expression decreases gradually over multiple passages and eventually hinders the rescue o ...
DOI:
10.1016/j.jviromet.2021.114099

15. Phylodynamic analyses of class I Newcastle disease virus isolated in China

Author:
Chen, Libin; Song, Jie; Liu, Hongzhi; Cai, Juncheng; Lin, Qiuyan; Xu, Chenggang; Ding, Chan; Liao, Ming; Ren, Tao; Xiang, Bin
Source:
Transboundary and emerging diseases 2021 v.68 no.3 pp. 1294-1304
ISSN:
1865-1674
Subject:
Avian orthoavulavirus 1,   etc   ; Bayesian theory; Newcastle disease; disease transmission; genetic analysis; genotype; monitoring; pathogens; poultry industry; risk; viruses; China;     Show all 12 Subjects
Abstract:
... Newcastle disease virus (NDV), the pathogen of Newcastle disease, has caused significant losses to the poultry industry worldwide. However, owing to its avirulence, class I NDVs have not been studied as much as class II NDVs. We aimed to epidemiologically monitor the spread of class I NDVs in China. We isolated 104 class I NDV strains from poultry in live poultry markets (LPMs) of Guangdong Provin ...
DOI:
10.1111/tbed.13785

16. Response of lymphatic tissues to natural feed additives, curcumin (Curcuma longa) and black cumin seeds (Nigella sativa), in broilers against Pasteurella multocida

Author:
Raheem, Muhammad Akmal; Jiangang, Hu; Yin, Dongdong; Xue, Mei; Rehman, Kashif ur; Rahim, Muhammad Ajwad; Gu, Yi; Fu, Dandan; Song, Xiangjun; Tu, Jian; Khan, Ibrar Muhammad; Tipu, M.Y.; Qi, Kezong
Source:
Poultry science 2021 v.100 no.5 pp. 101005
ISSN:
0032-5791
Subject:
Avian orthoavulavirus 1,   etc   ; Curcuma longa; Nigella sativa; Pasteurella multocida; antibiotics; curcumin; diet; feed conversion; hemagglutination; histopathology; mortality; turmeric;     Show all 12 Subjects
Abstract:
... The antibiotic residues and pathogenic resistance against the drug are very common in poultry because of antibiotics used in their feed. It is necessary to use natural feed additives as effective alternatives instead of a synthetic antibiotic. This study aimed to investigate the immune response of Nigella sativa and Curcuma longa in broilers under biological stress against Pasteurella multocida. T ...
DOI:
10.1016/j.psj.2021.01.028

17. Development of a reverse-transcription recombinase polymerase amplification assay with a lateral flow assay for rapid detection of avian orthoavulavirus 1

Author:
Fan, Jindai; Chen, Wenxian; Zhang, Yuanyuan; Liu, Zhixiang; Li, Xiaoming; Ding, Hongxing; Yi, Lin; Chen, Jinding; Zhao, Mingqiu
Source:
Journal of veterinary diagnostic investigation 2021 v.33 no.2 pp. 308-312
ISSN:
1943-4936
Subject:
Avian orthoavulavirus 1,   etc   ; Newcastle disease; birds; cross reaction; detection limit; poultry industry; rapid methods; recombinase polymerase amplification; reverse transcription;     Show all 9 Subjects
Abstract:
... Newcastle disease is an avian infectious disease caused by avian orthoavulavirus 1, also known as Newcastle disease virus (NDV). This disease has caused significant economic losses to the poultry industry worldwide. The rapid and simple detection of NDV infection is crucial to inform the appropriate control measures. We developed a reverse-transcription recombinase polymerase amplification (RT-RPA ...
DOI:
10.1177/1040638721990122

18. Surveillance and Genetic Characterization of Virulent Newcastle Disease Virus Subgenotype V.3 in Indigenous Chickens from Backyard Poultry Farms and Live Bird Markets in Kenya

Author:
Kariithi, Henry M.; Ferreira, Helena L.; Welch, Catharine N.; Ateya, Leonard O.; Apopo, Auleria A.; Zoller, Richard; Volkening, Jeremy D.; Williams-Coplin, Dawn; Parris, Darren J.; Olivier, Tim L.; Goldenberg, Dana; Binepal, Yatinder S.; Hernandez, Sonia M.; Afonso, Claudio L.; Suarez, David L.
Source:
Viruses 2021 v.13 no.1
ISSN:
1999-4915
Subject:
Avian orthoavulavirus 1,   etc   ; ; Newcastle disease; amino acids; chickens; farms; genome; monitoring; phylogeography; subgenotype; surveys; trade; virulence; viruses; Kenya;     Show all 15 Subjects
Abstract:
... Kenyan poultry consists of ~80% free-range indigenous chickens kept in small flocks (~30 birds) on backyard poultry farms (BPFs) and they are traded via live bird markets (LBMs). Newcastle disease virus (NDV) was detected in samples collected from chickens, wild farm birds, and other domestic poultry species during a 2017–2018 survey conducted at 66 BPFs and 21 LBMs in nine Kenyan counties. NDV nu ...
DOI:
10.3390/v13010103

19. Efficacy of a turkey herpesvirus double construct vaccine (HVT-ND-IBD) against challenge with different strains of Newcastle disease, infectious bursal disease and Marek’s disease viruses

Author:
van Hulten, Marielle C.W.; Cruz-Coy, Julio; Gergen, Linda; Pouwels, Henk; ten Dam, Gerdy B.; Verstegen, Iwan; de Groof, Ad; Morsey, Mo; Tarpey, Ian
Source:
Avian pathology 2021 v.50 no.1 pp. 18-30
ISSN:
1465-3338
Subject:
Avian orthoavulavirus 1,   etc   ; Infectious bursal disease virus; Meleagrid alphaherpesvirus 1; Newcastle disease; genes; infectious bursal disease; vaccination; vaccines; virulent strains;     Show all 9 Subjects
Abstract:
... A double construct vaccine of turkey herpesvirus (HVT) was prepared that contains the fusion (F) gene from Newcastle disease virus (NDV) and the viral protein 2 (VP2) gene from infectious bursal disease virus (IBDV). Safety of the vaccine (HVT-ND-IBD) was confirmed and efficacy was evaluated after subcutaneous (SC) vaccination at 1 day of age or the in ovo route of vaccination. Challenges were per ...
DOI:
10.1080/03079457.2020.1828567

20. Monoclonal antibodies specific for the hemagglutinin-neuraminidase protein define neutralizing epitopes specific for Newcastle disease virus genotype 2.VII from Egypt

Author:
Moharam, Ibrahim; Asala, Olayinka; Reiche, Sven; Hafez, Hafez; Beer, Martin; Harder, Timm; Grund, Christian
Source:
Virology journal 2021 v.18 no.1 pp. 86
ISSN:
1743-422X
Subject:
Avian orthoavulavirus 1,   etc   ; Newcastle disease; antigenic variation; concanavalin A; epitopes; genotype; glycoproteins; hemagglutination; hybridomas; mice; phylogeny; polyclonal antibodies; poultry; vaccination; virology; virulence; viruses; Egypt;     Show all 18 Subjects
Abstract:
... BACKGROUND: Newcastle disease is a devastating disease in poultry caused by virulent Newcastle disease virus (NDV), a paramyxovirus endemic in many regions of the world despite intensive vaccination. Phylogenetic analyses reveal ongoing evolution of the predominant circulating genotype 2.VII, and the relevance of potential antigenic drift is under discussion. To investigate variation within neutra ...
DOI:
10.1186/s12985-021-01540-0