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- Böke, Dominik, et al. Show all 9 Authors
- Cell 2017 v.168 no.3 pp. 400-412.e18
- direct contact; exocytosis; fluorescence microscopy; plasma membrane; secretory granules; yeasts
- ... The structural characterization of protein complexes in their native environment is challenging but crucial for understanding the mechanisms that mediate cellular processes. We developed an integrative approach to reconstruct the 3D architecture of protein complexes in vivo. We applied this approach to the exocyst, a hetero-octameric complex of unknown structure that is thought to tether secretory ...