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- Baśkiewicz-Masiuk, Magdalena, et al. Show all 7 Authors
- Lipids 2007 v.42 no.8 pp. 707-716
- dietary fat; conjugated linoleic acid; immune response; phagocytosis; monocytes; macrophages; cultured cells; prostaglandin synthase; gene expression regulation; messenger RNA; protein content; prostaglandins; human health
- ... Prostaglandin E₂ produced endogenously (by cyclooxygenases) can regulate macrophage phagocytosis. Cyclooxygenase activity reduction (mainly through inhibition of inducible Cox-2) can induce PGE₂ synthesis depression and can activate the phagocytosis process. There are no reports in the literature explaining whether conjugated linoleic acid dienes (trans-10, cis-12 CLA and cis-9, trans-11 CLA) modi ...
- Baśkiewicz-Masiuk, Magdalena, et al. Show all 10 Authors
- Nutrition 2008 v.24 no.2 pp. 187-199
- macrophages; cultured cells; in vitro studies; monocytes; leukemia; reactive oxygen species; conjugated linoleic acid; arachidonic acid; lipid peroxidation; atherosclerosis; inflammation; prostaglandins; gene expression; messenger RNA; cell differentiation; transcription factors; cell respiration; phospholipase A2; mitochondria
- ... Objective: Conjugated linoleic acids (CLAs) have potential antiatherosclerotic properties: they may inhibit atherosclerotic processes by reducing the intensity of inflammatory processes. However, in vivo studies have shown that the application of trans-10, cis-12 CLA in obese men increased their oxidative stress. The objective of this study was to determine whether CLA can lead to an increase in o ...