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- Bhardwaj, Neerupma, et al. Show all 7 Authors
- Journal of molecular biology 2019 v.431 no.4 pp. 777-793
- Mycobacterium tuberculosis; acetylation; enzyme activity; enzymes; metabolism; moieties; phosphorylation; regulatory proteins; signal transduction; transcription (genetics)
- ... Two-component signal transduction (TCS) cascades involve stimulus-dependent activation and phosphorylation of a sensor kinase (SK), which then transfers the phosphoryl moiety to the response regulator (RR) protein. The fidelity of this phosphotransfer reaction from the SK to the RR provides specificity to TCS signaling. In the present study, we show that for TcrX, a transcriptionally autoregulated ...