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- Bhatnagar, Sunali, et al. Show all 5 Authors
- Journal of Controlled Release 2016 v.238 pp. 22-30
- animal models; antibodies; drug formulations; hydrogels; immune response; immunoglobulin G; nanoparticles; ovalbumin; swine; ultrasonic treatment; vaccination; vaccines
- ... Inertial cavitation mediated by ultrasound has been previously shown to enable skin permeabilisation for transdermal drug and vaccine delivery, by sequentially applying the ultrasound then the therapeutic in liquid form on the skin surface. Using a novel hydrogel dosage form, we demonstrate that the use of sub-micron gas-stabilising polymeric nanoparticles (nanocups) to sustain and promote cavitat ...