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Bordetellabronchiseptica, etc ; Pasteurella multocida; chromosomes; genes; interleukin-10; live vaccines; mice; toxins; vaccination; virulence; Show all 10 Subjects
Abstract:
... Dermonecrotic toxin (DNT) is an important bacterial virulence factor produced by the zoonotic pathogens Bordetella bronchiseptica and Pasteurella multocida. This study aims to explore the possibility of expressing different fragments of P. multocida toxin (PMT) in the chromosome of attenuated B. bronchiseptica to generate single-component mucosal vaccine candidates. To achieve this, a 954-bp fragm ...
... Illegal migration of pigs/piglets from Myanmar to Mizoram is a common practice to meet the local demands. The migrated animals are suspected as potential carrier of various microbial pathogens. The present study was conducted on isolation, identification and molecular characterization of major bacterial pathogens (Actinobacillus pleuropneumoniae, Bordetella bronchiseptica, Haemophilus parasuis, My ...
... Currently, most researches focus on that constructed wetlands (CWs) achieve desirable removal of antibiotics, antibiotic resistance genes (ARGs) and human pathogens. However, few studies have assessed the fate of resistome components, especially the behavior and cooccurrence of ARGs, mobile genetic elements (MGEs) and virulence factors (VFs). Therefore, characteristics of microbial communities (MC ...
... Following a canine distemper virus (CDV) epizootic in 2011, serum samples of 45 live-trapped desert kit foxes (Vulpes macrotis arsipus) from the Upper Chuckwalla Valley, California, US, were tested for the presence of antibodies against CDV, canine parvovirus (CPV), canine herpes virus (CHV), canine adenovirus (CAV-2), and Toxoplasma gondii. Fecal swabs were tested by PCR for CPV genomic material, ...
... Respiratory disease in horses is caused by a multifactorial complex of infectious agents and environmental factors. An important pathogen in horses is equine herpesvirus type 1 (EHV-1). During co-evolution with this ancient alphaherpesvirus, the horse’s respiratory tract has developed multiple antiviral barriers. However, these barriers can become compromised by environmental threats. Pollens and ...
... BACKGROUND: Bacterial lower respiratory tract infections (bLRTIs) are common and potentially life threatening in cats and dogs. Antibiotic treatment is often initiated before the diagnosis of bLRTI; therefore improved knowledge of the aetiology and antibiotic susceptibility patterns of these infections is essential to inform empiric antibiotic choices. METHODS: A retrospective study of microbiolog ...
Bordetellabronchiseptica, etc ; X-radiation; cytoplasm; homeostasis; molecular dynamics; zinc; Show all 6 Subjects
Abstract:
... Zinc homeostasis in mammals is constantly and precisely maintained by sophisticated regulatory proteins. Among them, the Zrt/Irt-like protein (ZIP) regulates the influx of zinc into the cytoplasm. In this work, we have employed all-atom molecular dynamics simulations to investigate the Zn²⁺ transport mechanism in prokaryotic ZIP obtained from Bordetella bronchiseptica (BbZIP) in a membrane bilayer ...
... Vaccination guidelines for dogs and cats indicate that core vaccines (for dogs, rabies, distemper, adenovirus, parvovirus; for cats, feline parvovirus, herpes virus-1, calicivirus) are essential to maintain health, and that non-core vaccines be administered according to a clinician’s assessment of a pet’s risk of exposure and susceptibility to infection. A reliance on individual risk assessment in ...
Bordetellabronchiseptica, etc ; cough; immunity; live vaccines; nose; oral administration; oral vaccination; virulence; Show all 8 Subjects
Abstract:
... This experimental challenge study assessed immune protection 1 year after a single dose of live-attenuated oral Bordetella bronchiseptica (Bb) vaccine in dogs. Forty Bb-seronegative 7–9-week-old puppies were randomly assigned at Day 0 to receive a single oral dose of either Bb vaccine (n = 20; vaccinated group) or sterile water (n = 20; control group). Groups were housed separately until cominglin ...
Laura Bourque; Ole Nielsen; Mason Jager; Davor Ojkic; Chantale Provost; Carl A. Gagnon; Betty Lockerbie; Hein Snyman; Brian Stevens; David Needle; Shotaro Nakagun; Sherri Cox; Jessica Khodadad; Megan E. B. Jones
... Skunk adenovirus-1 (SkAdV-1) has been reported infecting several North American wildlife species; however, lesions associated with disease have not yet been completely characterized, particularly in porcupines. We describe and characterize the tissue distribution and lesions associated with SkAdV-1 infection in 24 wildlife diagnostic cases submitted between 2015 and 2020, including 16 North Americ ...
Bordetellabronchiseptica, etc ; cultivars; genes; genome-wide association study; peanuts; sequence analysis; transcription (genetics); Show all 7 Subjects
Abstract:
... Zinc/iron-regulated transporter-like protein (ZIP) family genes play crucial roles in metal uptake and transport in plants. However, little is known about their functions in peanut. Here, genome-wide analysis identified 30 peanut AhZIP genes that were divided into four classes. Most AhZIPs experienced whole-genome or segmental duplication. AhZIP proteins harbored 3–8 transmembrane domains and a ty ...
... Incidence of Bordetella pertussis, the causative agent of whooping cough, is rising in some global human populations despite high vaccination rates, and significant research is underway to address the issue. Baboons are an established model for pertussis research, but like many mammals, they can be naturally infected with Bordetella bronchiseptica. Because B. bronchiseptica interferes with B. pert ...
... Bordetella bronchiseptica is a respiratory animal pathogen that shows growing resistance to commonly used antibiotics, which has necessitated the examination of new antimicrobials, including bacteriophages. In this study, we examined the previously isolated and partially characterized B. bronchiseptica siphoviruses of the genus Vojvodinavirus (LK3, CN1, CN2, FP1 and MW2) for their ability to inhib ...
Bordetellabronchiseptica, etc ; Bordetella pertussis; Western blotting; asymmetry; cell structures; cost effectiveness; immunity; lipoproteins; peptidoglycans; phospholipids; polyacrylamide gel electrophoresis; protein composition; research; vaccines; Show all 14 Subjects
Abstract:
... Current vaccines against Bordetella pertussis do not prevent colonization and transmission of the bacteria, and vaccine-induced immunity wanes rapidly. Besides, efficacy of vaccines for Bordetella bronchiseptica remains unclear. Novel vaccines could be based on outer-membrane vesicles (OMVs), but vesiculation of bordetellae needs to be increased for cost-effective vaccine production. Here, we focu ...
Bordetellabronchiseptica, etc ; cough; dogs; immunity; nose; placebos; vaccination; vaccines; virulence; Show all 9 Subjects
Abstract:
... BACKGROUND: Very few studies have evaluated the duration of immunity of Bordetella bronchiseptica vaccines in dogs, and to date, no studies have been published on the duration of immunity of oral canine Bordetella bronchiseptica vaccines. This study was designed to determine the effectiveness of a single dose of an oral B bronchiseptica vaccine in dogs when challenged 13 months after vaccination. ...
Bordetellabronchiseptica, etc ; C-reactive protein; bronchopneumonia; dogs; radiography; retrospective studies; veterinary medicine; Show all 7 Subjects
Abstract:
... BACKGROUND: C‐reactive protein (CRP) is a well‐known acute‐phase protein in dogs that may discriminate bacterial bronchopneumonia from other pulmonary conditions. Bronchopneumonia caused by Bordetella bronchiseptica (Bb) is common but the associated increase in CRP concentration in naturally infected dogs has not been fully explored. OBJECTIVE: To compare CRP concentrations of dogs with Bb infecti ...
... We present a portable genetic analyzer with an integrated centrifugal disc which is equipped with a glass-filter extraction column for purifying nucleic acid (NA) and multiple reaction chambers for analyzing major feline upper respiratory tract disease (FURTD) pathogens. We targeted four kinds of FURTD including Feline herpesvirus 1 (FHV), Mycoplasma felis (MPF), Bordetella bronchiseptica (BDB), a ...
Bordetellabronchiseptica, etc ; Stenotrophomonas maltophilia; artificial colors; bioscouring; bleaching; decolorization; denim; indigo; laccase; pH; wastes; Show all 11 Subjects
Abstract:
... The aim of this present study was to investigate the environmental proficiency of two laccase producing bacterial strains, Hb16c and Berl11b2. Here, laccases, which were secreted in media containing environmental wastes, were characterized for biochemical and kinetic novelty and applied in the decolourization of some synthetic dyes and subsequently, denim bleaching. The laccases exhibited enhanced ...
Junsheng Dong; Wai Ning Tiffany Tsui; Xue Leng; Jinping Fu; Molly Lohman; Joseph Anderson; Vaughn Hamill; Nanyan Lu; Elizabeth Poulsen Porter; Mark Gray; Tesfaalem Sebhatu; Susan Brown; Roman Pogranichniy; Heng Wang; Lance Noll; Jianfa Bai
... Infectious respiratory disease is one of the most common diseases in dogs worldwide. Several bacterial and viral pathogens can serve as causative agents of canine infectious respiratory disease (CIRD), including Mycoplasma cynos, Mycoplasma canis, Bordetella bronchiseptica, canine adenovirus type 2 (CAdV-2), canine herpesvirus 1 (CHV-1), canine parainfluenza virus (CPIV), canine distemper virus (C ...
Bordetellabronchiseptica, etc ; dogs; gamithromycin; histopathology; intramuscular injection; lungs; models; piglets; respiratory tract diseases; signs and symptoms (animals and humans); Show all 10 Subjects
Abstract:
... In the Bordetella bronchiseptica infection model development study, twenty‐eight piglets were inoculated with B. bronchiseptica strain of either canine (10⁹ CFU/ml) or swine (10⁸ and 10⁹ CFU/ml) origin; swine origin strain at 10⁹ CFU/ml was chosen for the efficacy assessment study due to higher incidence and severity of gross and histopathological lesions compared with other strains. To assess eff ...