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- Cao, Tianyuan, et al. Show all 8 Authors
- Analytical chemistry 2018 v.90 no.9 pp. 5654-5663
- Pseudomonas aeruginosa; agar; biofilm; image analysis; ions; light microscopy; mass spectrometry; microbial communities; microorganisms; nitrogen; quinolones; statistical analysis
- ... After several decades of widespread use for mapping elemental ions and small molecular fragments in surface science, secondary ion mass spectrometry (SIMS) has emerged as a powerful analytical tool for molecular imaging in biology. Biomolecular SIMS imaging has primarily been used as a qualitative technique; although the distribution of a single analyte can be accurately determined, it is difficul ...