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- Chan, R.L.Y., et al. Show all 10 Authors
- Life sciences 2013 v.93 no.8 pp. 344-351
- Western blotting; acetylcysteine; anticarcinogenic activity; apoptosis; cell viability; colorectal neoplasms; cytosol; cytotoxicity; flow cytometry; free radical scavengers; membrane potential; mitochondria; mitochondrial membrane; neoplasm cells; oxidative phosphorylation
- ... AIMS: The therapeutic potential of various tanshinones was examined and compared for their anti-cancer activities on colon cancer cells. The role of ROS generation in the pro-apoptotic activity of dihydrotanshinone (DHTS) was further studied. MAIN METHODS: Cell viability was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Apoptosis and poly-ADP-ribose-po ...