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1. Phylogenetic analysis of infectious bronchitis virus circulating in southern China in 2016–2017 and evaluation of an attenuated strain as a vaccine candidate

Author:
Chen, Libin,   et al.   ; Xiang, Bin; Hong, Yanfen; Li, Qian; Du, Haoyun; Lin, Qiuyan; Liao, Ming; Ren, Tao; Xu, Chenggang;     Show all 9 Authors
Source:
Archives of virology 2021 v.166 no.1 pp. 73-81
ISSN:
0304-8608
Subject:
Infectious bronchitis virus; chicken eggs; chickens; farms; genotype; infection; infectious bronchitis; live vaccines; phylogeny; poultry industry; protective effect; respiratory tract diseases; safety testing; signs and symptoms (animals and humans); specific pathogen-free animals; strains; viral shedding; virology; China
Abstract:
... Avian infectious bronchitis (IB) is a highly contagious viral respiratory disease, caused by infectious bronchitis virus (IBV), that poses an important economic threat to the poultry industry. In recent years, genotypes GI-7, GI-13, and GI-19 have been the most prevalent IBV strains in China. However, in this study, we found that most IBV strains from southern China in 2016–2017 belonged to genoty ...
DOI:
10.1007/s00705-020-04851-9

2. Insights into Genomic Epidemiology, Evolution, and Transmission Dynamics of Genotype VII of Class II Newcastle Disease Virus in China

Author:
Chen, Libin,   et al.   ; Xiang, Bin; Cai, Juncheng; Liang, Jianpeng; Lin, Qiuyan; Xu, Chenggang; Ding, Chan; Liao, Ming; Ren, Tao;     Show all 9 Authors
Source:
Pathogens 2020 v.9 no.10
ISSN:
2076-0817
Subject:
Avian orthoavulavirus 1; amino acids; chickens; codon usage; dynamics; evolution; genetic variation; genomics; genotype; models; pathogens; poultry industry; sampling; strains; virulence; viruses; China
Abstract:
... Newcastle disease virus (NDV) is distributed worldwide and has caused significant losses to the poultry industry. Almost all virulent NDV strains belong to class II, among which genotype VII is the predominant genotype in China. However, the molecular evolution and phylodynamics of class II genotype VII NDV strains in China remained largely unknown. In this study, we identified 13 virulent NDV inc ...
DOI:
10.3390/pathogens9100837

3. Evolutionary Dynamics and Age-Dependent Pathogenesis of Sub-Genotype VI.2.1.1.2.2 PPMV-1 in Pigeons

Author:
Chen, Libin,   et al.   ; Xie, Peng; Zhang, Yifan; Lin, Qiuyan; Ding, Chan; Liao, Ming; Xu, Chenggang; Xiang, Bin; Ren, Tao;     Show all 9 Authors
Source:
Viruses 2020 v.12 no.4
ISSN:
1999-4915
Subject:
Bayesian theory; Respirovirus; bird diseases; death; genetic analysis; morbidity; pathogenesis; phylogeography; pigeons; sowing; subgenotype; viruses; China; Europe
Abstract:
... Pigeon paramyxovirus type 1 (PPMV-1) infection causes high morbidity in pigeons, resulting in a significant burden to the poultry industry. In this study, we isolated three PPMV-1 strains from diseased pigeons collected in Guangdong Province, South China, from June 2017 to April 2019. Genetic analysis revealed that these three PPMV-1 strains and most of the PPMV-1 strains isolated from China after ...
DOI:
10.3390/v12040433

4. Phylogeny, pathogenicity and transmissibility of a genotype XII Newcastle disease virus in chicken and goose

Author:
Chen, Libin,   et al.   ; Xiang, Bin; Chen, Ruojin; Liang, Jianpeng; Lin, Qiuyan; Sun, Minhua; Kang, Yinfeng; Ding, Chan; Liao, Ming; Xu, Chenggang; Ren, Tao;     Show all 11 Authors
Source:
Transboundary and emerging diseases 2020 v.67 no.1 pp. 159-170
ISSN:
1865-1674
Subject:
Avian orthoavulavirus 1; chickens; emerging diseases; geese; monitoring; mortality; pathogenicity; phylogeny; poultry diseases; signs and symptoms (animals and humans); subgenotype; vaccines; viruses; waterfowl; China; South Africa; Vietnam
Abstract:
... Although Newcastle disease virus (NDV) has a worldwide distribution, some NDV genotypes have more regional geographical ranges within continents. In this study, we isolated a subgenotype XIIb NDV strain, Goose/CH/GD/E115/2017 (E115), from geese in Guangdong province, Southern China, in 2017. Phylogenetic analysis showed that E115 and six other NDVs from geese in China were grouped under subgenotyp ...
DOI:
10.1111/tbed.13335

5. An Integrated Method for Accounting for Water Environmental Capacity of the River–Reservoir Combination System

Author:
Chen, Libin,   et al.   ; Zhao, Fen; Li, Chunhui; Zhang, Yuan;     Show all 4 Authors
Source:
Water 2018 v.10 no.4
ISSN:
2073-4441
Subject:
ammonium nitrogen; basins; chemical oxygen demand; drinking water; ecosystems; eutrophication; fluid mechanics; hydrologic models; pollutants; pollution control; river water; rivers; total nitrogen; total phosphorus; water pollution; water quality; China
Abstract:
... The security of drinking water is a serious issue in China and worldwide. As the backup source of drinking water for the Changde City in China, the Huangshi Reservoir suffers from the threat of eutrophication due to the water quality of the reservoir ecosystem being affected by the tributaries that carry Non-Point Source (NPS) pollutants. The calculation of the water environmental capacity (WEC) c ...
DOI:
10.3390/w10040483

6. Sensitivity analysis for the total nitrogen pollution of the Danjiangkou Reservoir based on a 3-D water quality model

Author:
Chen, Libin,   et al.   ; Yang, Zhifeng; Liu, Haifei;     Show all 3 Authors
Source:
Frontiers of earth science 2017 v.11 no.4 pp. 609-619
ISSN:
2095-0195
Subject:
air; biodiversity; human health; hydrologic models; nitrogen; nitrogen content; pollution; rivers; water quality; China
Abstract:
... Inter-basin water transfers containing a great deal of nitrogen are great threats to human health, biodiversity, and air and water quality in the recipient area. Danjiangkou Reservoir, the source reservoir for China’s South-to-North Water Diversion Middle Route Project, suffers from total nitrogen pollution and threatens the water transfer to a number of metropolises including the capital, Beijing ...
DOI:
10.1007/s11707-017-0650-3

7. Newcastle disease virus RNA-induced IL-1β expression via the NLRP3/caspase-1 inflammasome

Author:
Chen, Libin,   et al.   ; Gao, Pei; Fan, Lei; Ren, Jinlian; Du, Haoyun; Sun, Minhua; Li, Yaling; Xie, Peng; Lin, Qiuyan; Liao, Ming; Xu, Chenggang; Ning, Zhangyong; Ding, Chan; Xiang, Bin; Ren, Tao;     Show all 15 Authors
Source:
Veterinary research 2020 v.51 no.1 pp. 53
ISSN:
1297-9716
Subject:
Avian orthoavulavirus 1; Newcastle disease; RNA; body temperature; caspase-1; cell culture; chickens; inflammasomes; inflammation; interleukin-1beta; mortality; neutralizing antibodies; pathogenesis; ultracentrifugation; virulence; China
Abstract:
... Newcastle disease virus (NDV) infection causes severe inflammation and is a highly contagious disease in poultry. Virulent NDV strains (GM) induce large quantities of interleukin-1β (IL-1β), which is the central mediator of the inflammatory reaction. Excessive expression of IL-1β exacerbates inflammatory damage. Therefore, exploring the mechanisms underlying NDV-induced IL-1β expression can aid in ...
DOI:
10.1186/s13567-020-00774-0
PubMed:
32293543
PubMed Central:
PMC7156904

8. Assessing the eutrophication risk of the Danjiangkou Reservoir based on the EFDC model

Author:
Chen, Libin,   et al.   ; Yang, Zhifeng; Liu, Haifei;     Show all 3 Authors
Source:
Ecological engineering 2016 v.96 pp. 117-127
ISSN:
0925-8574
Subject:
algae; ammonium nitrogen; chlorophyll; dissolved oxygen; eutrophication; models; risk; sediments; trophic levels; water management; water quality; water reservoirs; China
Abstract:
... As the source reservoir of the middle route of China's South-to-North Water Diversion Project, the Danjiangkou Reservoir suffers from eutrophication threatens. Thus, it is necessary to develop an eutrophication model for local water resource management. In this study, a three-dimensional (3-D) eutrophication model for the Danjiangkou Reservoir was constructed. The model is different from the exist ...
DOI:
10.1016/j.ecoleng.2016.02.021

9. Pathogenicity and transmissibility of a highly pathogenic avian influenza virus H5N6 isolated from a domestic goose in Southern China

Author:
Chen, Libin,   et al.   ; Xiang, Bin; Liang, Jianpeng; You, Renrong; Han, Lujie; Mei, Kun; Chen, Ruojing; Zhang, Yifan; Dai, Xu; Gao, Pei; Liao, Ming; Xiao, Chencheng; Ren, Tao;     Show all 13 Authors
Source:
Veterinary microbiology 2017 v.212 pp. 16-21
ISSN:
0378-1135
Subject:
Influenza A virus; chickens; geese; host range; monitoring; pathogenicity; phenotype; pigeons; risk; viruses; waterfowl; China; Laos
Abstract:
... Since the first outbreak of H5N6 reported in Laos at 2013, there has been a dramatic increase in H5N6 strains isolated from waterfowl in China, particularly Southern China. However, pathogenicity and transmissibility of the virus in different birds remain largely unknown. In this study, a novel H5N6 virus, termed QY01, that belonged to group C in 2.3.4.4 was isolated from an apparently healthy dom ...
DOI:
10.1016/j.vetmic.2017.10.022

10. Multiprotein-bridging factor 1 regulates vegetative growth, osmotic stress, and virulence in Magnaporthe oryzae

Author:
Chen, Libin,   et al.   ; Fan, Gaili; Zhang, Kai; Huang, Hao; Zhang, Heng; Zhao, Ao; Chen, Ruiqi; Li, Guangpu; Wang, Zonghua; Lu, Guo-dong;     Show all 10 Authors
Source:
Current genetics 2017 v.63 no.2 pp. 293-309
ISSN:
0172-8083
Subject:
Arabidopsis thaliana; Drosophila melanogaster; Homo sapiens; Magnaporthe oryzae; Saccharomyces cerevisiae; TATA box; amino acids; binding proteins; bioinformatics; blast disease; fungi; hydrogen peroxide; models; mutants; osmotic stress; phylogeny; sodium chloride; sorbitol; stress response; transcriptional activation; vegetative growth; virulence
Abstract:
... Multiprotein bridging factor 1 (MBF1) is a transcriptional co-activator that mediates transcriptional activation by bridging sequence-specific activator like proteins and the TATA-box binding protein (TBP). MBF1 has been well-studied in Arabidopsis thaliana, Saccharomyces cerevisiae, Drosophila melanogaster, and Homo sapiens, but it is not well understood in filamentous fungi. In this study, we re ...
DOI:
10.1007/s00294-016-0636-9

11. One-step synthesis of polyhydroquinone–graphene hydrogel composites for high performance supercapacitors

Author:
Chen, Libin,   et al.   ; Wu, Jifeng; Zhang, Aijuan; Zhou, Anan; Huang, Zhifeng; Bai, Hua; Li, Lei;     Show all 7 Authors
Source:
Journal of materials chemistry A 2015 v.3 no.31 pp. 16033-16039
ISSN:
2050-7496
Subject:
capacitance; electrical conductivity; electrodes; graphene; graphene oxide; hydrogels; hydroquinone; polymers; quinones; surface area
Abstract:
... Electroactive polymers constitute an important class of electrode materials for supercapacitors based on pseudocapacitance. However, it is difficult to utilize low-conductive electroactive polymers in supercapacitors, although these polymers may have large theoretical specific capacitance. In this article, we designed and prepared a novel type of electrode material, with a unique structure of low- ...
DOI:
10.1039/c5ta03881b

12. Basic aluminum sulfate@graphene hydrogel composites: preparation and application for removal of fluoride

Author:
Chen, Libin,   et al.   ; Chen, Yunqiang; Zhang, Qingkun; Bai, Hua; Li, Lei;     Show all 5 Authors
Source:
Journal of materials chemistry A 2013 v.1 no.42 pp. 13101-13110
ISSN:
2050-7496
Subject:
adsorbents; adsorption; aluminum; aluminum sulfate; anions; fluorides; graphene; greenhouse gases; hydrogels; models; pH; sorption isotherms; temperature
Abstract:
... Porous composites based on basic aluminum sulfate and graphene hydrogel (BAS@GHG) were prepared via homogeneous precipitation of BAS in GHG, and used as adsorbents for fluoride removal from water. The BAS@GHG composites have a porous structure with a chemically converted graphene three dimensional network coated by a thin layer of amorphous BAS. These composites showed high adsorption capacities o ...
DOI:
10.1039/c3ta13285d

13. Graphene oxide–chitosan composite hydrogels as broad-spectrum adsorbents for water purification

Author:
Chen, Libin,   et al.   ; Chen, Yunqiang; Bai, Hua; Li, Lei;     Show all 4 Authors
Source:
Journal of materials chemistry A 2013 v.1 no.6 pp. 1992-2001
ISSN:
2050-7496
Subject:
adsorbents; adsorption; crosslinking; dyes; electrostatic interactions; filtration; graphene; heavy metals; hydrogels; metal ions; water pollution; water purification
Abstract:
... Water pollution is one of the most pervasive problems afflicting people throughout the world, while adsorption is the most widely used method to remove the contaminants from water. Here, in this paper, we report an eco-friendly graphene oxide–chitosan (GO–CS) hydrogel as a new type of adsorbent for water purification. The GO–CS hydrogels were prepared via self-assembly of GO sheets and CS chains. ...
DOI:
10.1039/c2ta00406b

14. Electrochemical supercapacitor with polymeric active electrolyte

Author:
Chen, Libin,   et al.   ; Chen, Yanru; Wu, Jifeng; Wang, Jianwei; Bai, Hua; Li, Lei;     Show all 6 Authors
Source:
Journal of materials chemistry A 2014 v.2 no.27 pp. 10526-10531
ISSN:
2050-7496
Subject:
capacitance; electrochemistry; electrodes; electrolytes; energy; polyaniline; redox reactions; water solubility
Abstract:
... An electrochemical supercapacitor with a polymeric active electrolyte was designed and fabricated in this work. A water-soluble conducting polymer, sulfonated polyaniline (SPAni), was used in the supercapacitor as the active electrolyte and a semipermeable membrane was employed as the separator of the device. It was found that SPAni in the electrolyte can provide pseudocapacitance via its reversib ...
DOI:
10.1039/c4ta01319k

15. Critical limitations of prognostic signatures based on risk scores summarized from gene expression levels: a case study for resected stage I non-small-cell lung cancer

Author:
Chen, Libin,   et al.   ; Qi, Lishuang; Li, Yang; Qin, Yuan; Pan, Rufei; Zhao, Wenyuan; Gu, Yunyan; Wang, Hongwei; Wang, Ruiping; Chen, Xiangqi; Guo, Zheng;     Show all 11 Authors
Source:
Briefings in bioinformatics 2016 v.17 no.2 pp. 233-242
ISSN:
1477-4054
Subject:
case studies; data collection; gene expression; genes; lung neoplasms; microarray technology; prognosis; risk
Abstract:
... Most of current gene expression signatures for cancer prognosis are based on risk scores, usually calculated as some summaries of expression levels of the signature genes, whose applications require presetting risk score thresholds and data normalization. In this study, we demonstrate the critical limitations of such type of signatures that the risk scores of samples will change greatly when they ...
DOI:
10.1093/bib/bbv064

16. Preparation of Water-Soluble Hyperbranched Polyester Nanoparticles with Sulfonic Acid Functional Groups and Their Micelles Behavior, Anticoagulant Effect and Cytotoxicity

Author:
Chen, Libin,   et al.   ; Han, Qiaorong; Chen, Xiaohan; Niu, Yanlian; Zhao, Bo; Wang, Bingxiang; Mao, Chun; Shen, Jian;     Show all 8 Authors
Source:
Langmuir 2013 v.29 no.26 pp. 8402-8409
ISSN:
1520-5827
Subject:
micelles; complement; coagulation; polyesters; cytotoxicity; anticoagulant activity; hydrophilicity; erythrocytes; nanomedicine; hydrophobicity; hemolysis; platelet activation; sulfonic acids; nanoparticles; biocompatibility; moieties
Abstract:
... Biocompatibility of nanoparticles has been attracting great interest in the development of nanoscience and nanotechnology. Herein, the aliphatic water-soluble hyperbranched polyester nanoparticles with sulfonic acid functional groups (HBPE-SO₃ NPs) were synthesized and characterized. They are amphiphilic polymeric nanoparticles with hydrophobic hyperbranched polyester (HBPE) core and hydrophilic s ...
DOI:
10.1021/la400836y

17. Preparation of PNIPAM-g-P (NIPAM-co-St) microspheres and their blood compatibility

Author:
Chen, Libin,   et al.   ; Zhu, Qinshu; Zhu, Peiyuan; Luan, Jianfeng; Mao, Chun; Huang, Xiaohua; Shen, Jian;     Show all 7 Authors
Source:
Colloids and Surfaces B: Biointerfaces 2013 v.104 pp. 61-65
ISSN:
0927-7765
Subject:
blood; chemical structure; coagulation; colloids; complement; cytotoxicity; emulsions; hemolysis; platelet activation; polymerization; therapeutics
Abstract:
... The poly(N-isopropylacrylamide)-g-poly(N-isopropylacrylamide-co-styrene) microspheres (PNNS-MSs) were prepared by an emulsifier-free emulsion polymerization method. The blood compatibility of PNNS-MSs was characterized by in vitro for coagulation tests, hemolysis assay, plasma recalcification time, complement activation, platelet activation, and cytotoxicity experiments. The results showed that th ...
DOI:
10.1016/j.colsurfb.2012.12.004

18. Hemocompatible and antibiofouling PU-F127 nanospheres platform for application to glucose detection in whole blood

Author:
Chen, Libin,   et al.   ; Sun, Chong; Xu, Fujian; Zhu, Peiyuan; Luan, Jianfeng; Mao, Chun; Shen, Jian;     Show all 7 Authors
Source:
Journal of materials chemistry B 2013 v.1 no.6 pp. 801-809
ISSN:
2050-7518
Subject:
anticoagulants; ascorbic acid; biocompatibility; biosensors; blood; blood glucose; carbon electrodes; detection limit; diagnostic techniques; electrochemistry; electron transfer; glucose; glucose oxidase; human health; nanospheres; uric acid
Abstract:
... Analysts are always enthusiastic about finding new materials with good biocompatibility to improve the behavior of biosensors. In this case, a novel electrochemical biosensor, which can be conveniently applied to veraciously evaluate the level of blood glucose with the help of antibiofouling technology, was prepared and investigated. More details of the preparation of polyurethane-Pluronic F127 (P ...
DOI:
10.1039/c2tb00396a

19. Preparation, blood compatibility and anticoagulant effect of heparin-loaded polyurethane microspheres

Author:
Chen, Libin,   et al.   ; Tong, Fengyu; Chen, Xiaoqiang; Zhu, Peiyuan; Luan, Jianfeng; Mao, Chun; Bao, Jianchun; Shen, Jian;     Show all 8 Authors
Source:
Journal of materials chemistry B 2012 v.1 no.4 pp. 447-453
ISSN:
2050-7518
Subject:
anticoagulant activity; anticoagulants; biocompatibility; chemical composition; coagulation; complement; cytotoxicity; hemolysis; heparin; microparticles; nanotechnology; platelet activation; polyurethanes; separation
Abstract:
... Recent advances in micro- and nanotechnology have provided a variety of particles with highly controlled shapes, sizes, chemical composition, and interesting properties. In this work, a novel kind of heparin-functionalized polyurethane microsphere (Hep-PU MS) was synthesized by a single-step phase separation method. The blood compatibility and anticoagulant effect of the Hep-PU MSs were investigat ...
DOI:
10.1039/c2tb00250g