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- Cho, Ahreum, et al. Show all 11 Authors
- Archives of biochemistry and biophysics 2018 v.646 pp. 90-97
- albumins; animal models; biomarkers; blood serum; early diagnosis; excretion; fatty acid metabolism; glucose; kidney diseases; metabolites; metabolomics; mice; nuclear magnetic resonance spectroscopy; pathophysiology; tricarboxylic acid cycle; urine
- ... Diabetic kidney disease (DKD) involves various pathogenic processes during progression to end stage renal disease, and activated metabolic pathways might be changing based on major pathophysiologic mechanisms as DKD progresses. In this study, nuclear magnetic resonance spectroscopy (NMR)-based metabolic profiling was performed in db/db mice to suggest potential biomarkers for early detection and i ...