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- Choi, Eui Yul, et al. Show all 10 Authors
- Archives of pharmacal research 2007 v.30 no.5 pp. 624-633
- astrocytes; cerebral cortex; interferon-gamma; interleukin-4; lipopolysaccharides; metalloproteinases; mitogen-activated protein kinase; rats; signal transduction
- ... In spite of their pathophysiological importance in neuro-inflammatory diseases, little is known about the signal transduction pathways that lead to the induction of matrix metalloproteinases (MMPs) in the central nervous system. We reported previously that lipopolysaccharide (LPS) induced MMP-9 expression through ERK1/2 pathway in rat primary astrocytes(Glia 41:15–24, 2003). Here, we investigated ...