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1. Assessment and comparison of phytochemicals and antioxidant properties from various parts of the Australian maroon bush (Scaevola spinescens)

Author:
Christopher J. Scarlett,   et al.   ; Kien Q. Nguyen; Quan V. Vuong;     Show all 3 Authors
Source:
Heliyon 2021 v.7 no.4 pp. e06810
ISSN:
2405-8440
Subject:
Scaevola; antioxidants; bark; leaves; luteolin; medicinal plants; saponins; stemwood; Australia
Abstract:
... Scaevola spinescens is endemic to Australia and traditionally used as a medicinal plant. While its bioactive compounds have been studied, their concentrations in different parts of the plant have not been reported. This study compared total phenolic content (TPC), flavonoids, saponins and antioxidant properties, as well as major individual phytochemical compounds in the whole root, root bark, root ...
DOI:
10.1016/j.heliyon.2021.e06810

2. Changes of phytochemicals and antioxidant capacity of banana peel during the ripening process; with and without ethylene treatment

Author:
Christopher J. Scarlett,   et al.   ; Hang T. Vu; Quan V. Vuong;     Show all 3 Authors
Source:
Scientia horticulturae 2019 v.253 pp. 255-262
ISSN:
0304-4238
Subject:
antioxidant activity; banana peels; bananas; byproducts; carotenoids; chlorophyll; color; dietary fiber; ethylene; flavonoids; food industry; fruits; proanthocyanidins; ripening
Abstract:
... Banana peel is a by-product from the food industry, which is rich in dietary fiber and phenolic compounds. It is hypothesised that physicochemical and antioxidant properties of banana peel are significantly changed through different ripening stages. Ethylene treatment for fastening ripening is presumed to influence the changes in physicochemical and antioxidant properties of the peel. As such, thi ...
DOI:
10.1016/j.scienta.2019.04.043

3. Independent and Interactive Influences of Environmental UVR, Vitamin D Levels, and Folate Variant MTHFD1-rs2236225 on Homocysteine Levels

Author:
Christopher J. Scarlett,   et al.   ; Patrice Jones; Mark Lucock; Charlotte Martin; Rohith Thota; Manohar Garg; Zoe Yates; Martin Veysey; Emma Beckett;     Show all 9 Authors
Source:
Nutrients 2020 v.12 no.5 pp. -
ISSN:
2072-6643
Subject:
dosage; elderly; erythrocytes; folic acid; genetic variation; genotyping; homocysteine; multivariate analysis; nutrients; prediction; risk factors; ultraviolet radiation; vascular diseases; vitamin D
Abstract:
... Elevated homocysteine (Hcy) levels are a risk factor for vascular diseases. Recently, increases in ultraviolet radiation (UVR) have been linked to decreased Hcy levels. This relationship may be mediated by the status of UVR-responsive vitamins, vitamin D and folate, and/or genetic variants influencing their levels; however, this has yet to be examined. Therefore, the independent and interactive in ...
DOI:
10.3390/nu12051455

4. Starch-based edible coating formulation: Optimization and its application to improve the postharvest quality of “Cripps pink” apple under different temperature regimes

Author:
Christopher J. Scarlett,   et al.   ; Rahul Thakur; Penta Pristijono; Michael Bowyer; S.P. Singh; Quan V. Vuong;     Show all 6 Authors
Source:
Food packaging and shelf life 2019 v.22 pp. 100409
ISSN:
2214-2894
Subject:
antioxidant activity; apples; cell respiration; color; edible coatings; fatty acid esters; firmness; food packaging; free radical scavengers; fruit quality; fruit weight; fruits; glycerol; nutritive value; permeability; phenolic compounds; postharvest storage; response surface methodology; rice starch; shelf life; starch; sucrose; temperature; titratable acidity; total soluble solids; weight loss
Abstract:
... This study demonstrated Response Surface Methodology (RSM) optimisation of starch edible coating formulation and its application on apple fruit quality and storage life at two different temperatures (20 °C and 5 °C + 1 day at 20 °C). Films were optimised for physical, mechanical and permeability properties and the optimal formulation was sprayed over the fruit surface. Fruit weight loss, respirati ...
DOI:
10.1016/j.fpsl.2019.100409

5. Genetic Variation in the Bitter Receptors Responsible for Epicatechin Detection Are Associated with BMI in an Elderly Cohort

Author:
Christopher J. Scarlett,   et al.   ; Alexandria Turner; Martin Veysey; Simon Keely; Mark Lucock; Emma L. Beckett;     Show all 6 Authors
Source:
Nutrients 2021 v.13 no.2 pp. -
ISSN:
2072-6643
Subject:
DNA; alleles; antioxidants; blood; body mass index; chronic diseases; detection; digestive tract; elderly; epicatechin; food intake; genetic variation; genotyping; homozygosity; mortality; obesity; polyphenols; risk; taste
Abstract:
... Globally, more than one-third of adults are overweight. Overweight and obesity are complex and multifaceted conditions, associated with an increased risk of chronic illness and early mortality. While there are known risk factors, these alone do not fully explain the varying outcomes between individuals. Recently, taste receptors have been proposed to have a role in the risk for obesity. These rece ...
DOI:
10.3390/nu13020571

6. Encapsulation of phenolic-rich extract from banana (Musa cavendish) peel

Author:
Christopher J. Scarlett,   et al.   ; Hang T. Vu; Quan V. Vuong;     Show all 3 Authors
Source:
Journal of food science and technology 2020 v.57 no.6 pp. 2089-2098
ISSN:
0022-1155
Subject:
Musa; antioxidant activity; banana peels; bananas; bioactive compounds; byproducts; coatings; dopamine; drying temperature; encapsulation; gum arabic; healthy diet; ingredients; maltodextrins; phenolic compounds; phytochemicals; spray drying; storage conditions; water content
Abstract:
... Banana peel, a by-product rich in phenolics and other bioactive compounds, has great potentials as a natural preservative or healthy food ingredient. However, the instability of bioactive compounds derived from banana peel limits their applications, and as such encapsulation is necessary to improve their stability and widen their applications. This study investigated the impact of spray drying con ...
DOI:
10.1007/s13197-020-04243-6

7. Interactions between taste receptors and the gastrointestinal microbiome in inflammatory bowel disease

Author:
Christopher J. Scarlett,   et al.   ; Alexandria Turner; Eileen Chijoff; Martin Veysey; Simon Keely; Mark Lucock; Emma L. Beckett;     Show all 7 Authors
Source:
Journal of nutrition & intermediary metabolism 2019 v.18 pp. 100106
ISSN:
2352-3859
Subject:
alcohols; animals; digestive tract; dysbiosis; environmental factors; etiology; food intake; gastrointestinal system; genetics; inflammatory bowel disease; intestinal microorganisms; metabolism; respiratory system; risk; taste; therapeutics
Abstract:
... Incidence rates of inflammatory bowel disease (IBD) are increasing worldwide. This correlates with increased consumption of red meats, alcohol, refined sugars, oils and animal fats, typical of a “Western” diet. Poor dietary habits are the most ubiquitous environmental factor implicated in IBD, along with gastrointestinal dysbiosis. Taste genetics and oral receptor expression levels determine dieta ...
DOI:
10.1016/j.jnim.2019.100106

8. In vitro anti-pancreatic cancer activity of HPLC-derived fractions from Helicteres hirsuta Lour. stem

Author:
Christopher J. Scarlett,   et al.   ; Hong Ngoc Thuy Pham; Quan Van Vuong; Michael C. Bowyer;     Show all 4 Authors
Source:
Molecular biology reports 2020 v.47 no.2 pp. 897-905
ISSN:
0301-4851
Subject:
Helicteres; apoptosis; caffeic acid; cell cycle checkpoints; cucurbitacins; death; drug therapy; flow cytometry; interphase; molecular biology; pancreatic neoplasms; rosmarinic acid; sagerinic acid; usnic acid
Abstract:
... Pancreatic cancer (PC) is one of the leading causes of cancer death in Western societies. The absence of specific symptoms, late diagnosis and the resistance towards chemotherapy result in significant treatment difficulties. As such, it is important to find more effective therapeutic agents for the treatment of PC. Helicteres hirsuta Lour. (H. hirsuta) has been traditionally used in many countries ...
DOI:
10.1007/s11033-019-05180-0

9. Comparison of chemical profile and antioxidant properties of the brown algae

Author:
Christopher J. Scarlett,   et al.   ; Thanh T. Dang; Michael C. Bowyer; Ian A. Van Altena;     Show all 4 Authors
Source:
International journal of food science & technology 2018 v.53 no.1 pp. 174-181
ISSN:
0950-5423
Subject:
2,2-diphenyl-1-picrylhydrazyl; Hormosira banksii; Padina; Phyllospora comosa; Sargassum linearifolium; alpha-tocopherol; antioxidant activity; ascorbic acid; bioactive compounds; butylated hydroxytoluene; food industry; pharmaceutical industry
Abstract:
... Six brown algae, Sargassum vestitum, Sargassum linearifolium, Phyllospora comosa, Padina sp., Hormosira banksii and Sargassum podocanthum, were investigated for the chemical profile and antioxidant activity. The results showed that the extracts H. banksii, S. vestitum and Padina sp. indicated the significantly higher total phenolic compound (TPC) and antioxidant activities (ABTS, DPPH and FRAP) co ...
DOI:
10.1111/ijfs.13571

10. Ultrasound‐assisted extraction of Catharanthus roseus (L.) G. Don (Patricia White cultivar) stem for maximizing saponin yield and antioxidant capacity

Author:
Christopher J. Scarlett,   et al.   ; Hong Ngoc Thuy Pham; Quan Van Vuong; Michael C. Bowyer;     Show all 4 Authors
Source:
Journal of food processing and preservation 2018 v.42 no.5 pp. e13597
ISSN:
0145-8892
Subject:
2,2-diphenyl-1-picrylhydrazyl; Catharanthus roseus; alkaloids; antioxidant activity; antioxidants; bioactive compounds; cosmetics; cultivars; cytotoxicity; experimental design; functional foods; leaves; pharmaceutical industry; response surface methodology; roots; saponins; stems; temperature; ultrasonic treatment; ultrasonics; wastes
Abstract:
... Large quantities of Catharanthus roseus leaf have been used for the extraction of alkaloids, which results in a significant amount of waste that includes the stems, roots, and the extracted leaves. This study aimed to determine the optimal extraction conditions, by applying response surface methodology with Box–Behnken design to assess the interactive effect of ultrasonic parameters, including ult ...
DOI:
10.1111/jfpp.13597

11. Maximising recovery of phenolic compounds and antioxidant properties from banana peel using microwave assisted extraction and water

Author:
Christopher J. Scarlett,   et al.   ; Hang T. Vu; Quan V. Vuong;     Show all 3 Authors
Source:
Journal of food science and technology 2019 v.56 no.3 pp. 1360-1370
ISSN:
0022-1155
Subject:
antioxidant activity; banana peels; irradiation; microwave treatment; pH; phenolic compounds; response surface methodology; solvents
Abstract:
... Banana peel is rich in phenolic compounds and is generally considered as waste. This study aimed to maximise recovery of phenolics from banana peel using water via microwave assisted extraction. The impact of various parameters including pH of solvent, sample to solvent ratio, irradiation time with/without cooling periods, and irradiation power were investigated individually. Following this, extra ...
DOI:
10.1007/s13197-019-03610-2
PubMed:
30956315
PubMed Central:
PMC6423337

12. Optimization of ultrasound‐assisted extraction conditions for recovery of phenolic compounds and antioxidant capacity from banana (Musa cavendish) peel

Author:
Christopher J. Scarlett,   et al.   ; Hang T. Vu; Quan V. Vuong;     Show all 3 Authors
Source:
Journal of food processing and preservation 2017 v.41 no.5 pp. -
ISSN:
0145-8892
Subject:
Musa; acetone; antioxidant activity; banana peels; bananas; byproducts; flavonoids; food industry; functional foods; pharmaceutical industry; proanthocyanidins; response surface methodology; solvents; temperature; ultrasonic treatment; ultrasonics; wastes
Abstract:
... A large quantity of banana peel is generated annually and is considered as waste with low value. This study aimed to optimize five extraction parameters; including ultrasonic temperature, time and power, as well as acetone concentration and sample to solvent ratio, for maximum recovery of phenolic compounds, flavonoids, proanthocyanidins and antioxidant properties from banana (Musa cavendish) peel ...
DOI:
10.1111/jfpp.13148

13. Adsorption/desorption characteristics and enrichment of quercetin, luteolin and apigenin from Flos populi using macroporous resin

Author:
Christopher J. Scarlett,   et al.   ; Ying Zhang; Biying Wang; Zheng Jia; Zunlai Sheng;     Show all 5 Authors
Source:
Revista Brasileira de Farmacognosia 2019 v.29 no.1 pp. 69-76
ISSN:
0102-695X
Subject:
Populus tomentosa; adsorption; apigenin; desorption; luteolin; porous media; quercetin; resins
Abstract:
... In this study, the adsorption/desorption characteristics of quercetin, luteolin and apigenin from Flos populi extract (Populus tomentosa Carrière, Salicaceae) on twelve macroporous resins (NKA-9, HPD-600, HPD-826, HPD-750, HPD-400, DM-130, AB-8, SP-825, X-5, D-101, HPD-100, HPD-200) were evaluated. Both high adsorption and desorption capacities of quercetin, luteolin and apigenin from Flos populi ...
DOI:
10.1016/j.bjp.2018.09.002

14. Screening phytochemical content, antioxidant, antimicrobial and cytotoxic activities of Catharanthus roseus (L.) G. Don stem extract and its fractions

Author:
Christopher J. Scarlett,   et al.   ; Hong Ngoc Thuy Pham; Jennette A. Sakoff; Quan Van Vuong; Michael C. Bowyer;     Show all 5 Authors
Source:
Biocatalysis and agricultural biotechnology 2018 v.16 pp. 405-411
ISSN:
1878-8181
Subject:
Catharanthus roseus; Escherichia coli; antioxidant activity; antioxidants; apigenin; bioactive compounds; breasts; butanol; cell lines; colon; cytotoxicity; drugs; gallic acid; glioblastoma; high performance liquid chromatography; kaempferol; liquid-liquid extraction; lungs; methanol; neoplasm cells; pancreas; saponins; screening; therapeutics; ultrasonic treatment
Abstract:
... The aims of this study were to screen the phytochemical content, antioxidant, antimicrobial and cytotoxic properties of the extract and its fractions prepared from Catharanthus roseus (L.) G. Don (C. roseus) stem. C. roseus stem was powdered and extracted with methanol using ultrasound-assisted extraction to obtain the crude extract. The crude extract was further fractioned using liquid-liquid ext ...
DOI:
10.1016/j.bcab.2018.09.005

15. Encapsulation of Citrus By-Product Extracts by Spray-Drying and Freeze-Drying Using Combinations of Maltodextrin with Soybean Protein and ι-Carrageenan

Author:
Christopher J. Scarlett,   et al.   ; Konstantinos Papoutsis; John B. Golding; Quan Vuong; Penta Pristijono; Costas E. Stathopoulos; Michael Bowyer;     Show all 7 Authors
Source:
Foods 2018 v.7 no.7 pp. -
ISSN:
2304-8158
Subject:
Citrus; X-ray diffraction; antioxidant activity; byproducts; crystal structure; encapsulation; flavonoids; freeze drying; iota-carrageenan; iron; lemons; maltodextrins; microparticles; scanning electron microscopy; soy protein; spray drying; water activity; water content
Abstract:
... The effect of different combinations of maltodextrin (MD) coating agents (MD, MD + soybean protein, and MD + ι-carrageenan) on the encapsulation of lemon by-product aqueous extracts using freeze-drying and spray-drying were investigated. The total phenolic content (TPC), total flavonoid content (TFC), and ferric ion reducing antioxidant power (FRAP) of the microparticles were evaluated. Freez ...
DOI:
10.3390/foods7070115
PubMed:
30029543
PubMed Central:
PMC6069085

16. Optimization of ultrasound-assisted extraction of Helicteres hirsuta Lour. for enhanced total phenolic compound and antioxidant yield

Author:
Christopher J. Scarlett,   et al.   ; Hong N.T. Pham; Quan Van Vuong; Michael C. Bowyer;     Show all 4 Authors
Source:
Journal of applied research on medicinal and aromatic plants 2017 v.7 pp. 113-123
ISSN:
2214-7861
Subject:
2,2-diphenyl-1-picrylhydrazyl; Helicteres; antioxidant activity; antioxidants; applied research; bioactive compounds; diabetes; essential oil crops; flavonoids; malaria; methanol; pharmaceutical industry; response surface methodology; solvents; temperature; traditional medicine; ultrasonic treatment; ultrasonics
Abstract:
... Using response surface methodology, this study aimed to optimize five different ultrasound extraction parameters; including ultrasonic temperature, ultrasonic time, ultrasonic power, sample-to-solvent ratio and methanol concentration, for maximal extraction of bioactive compounds and antioxidant capacity from Helicteres hirsuta Lour. (H. hirsuta), which has been used as a traditional medicine for ...
DOI:
10.1016/j.jarmap.2017.07.002

17. Folate and Inflammation – links between folate and features of inflammatory conditions

Author:
Christopher J. Scarlett,   et al.   ; Patrice Jones; Mark Lucock; Martin Veysey; Emma L. Beckett;     Show all 5 Authors
Source:
Journal of nutrition & intermediary metabolism 2019 v.18 pp. 100104
ISSN:
2352-3859
Subject:
DNA; folic acid; homocysteine; inflammation; metabolism; methionine; nucleotides; nutrition; pathogenesis
Abstract:
... Folate serves as a cofactor for one-carbon (1C) transfer reactions. These reactions are involved in the synthesis of DNA nucleotides, the amino acid methionine, and in the regulation of homocysteine (Hcy) levels. Emerging evidence suggests that these reactions have roles in the development and maintenance of inflammatory responses, with optimal folate availability having key importance in preventi ...
DOI:
10.1016/j.jnim.2019.100104

18. Elaeocarpus reticulatus fruit extracts reduce viability and induce apoptosis in pancreatic cancer cells in vitro

Author:
Christopher J. Scarlett,   et al.   ; Alexandria Turner; Danielle R. Bond; Quan V. Vuong; Anita Chalmers; Emma L. Beckett; Judith Weidenhofer;     Show all 7 Authors
Source:
Molecular biology reports 2020 v.47 no.3 pp. 2073-2084
ISSN:
0301-4851
Subject:
Elaeocarpus; acetone; antioxidants; apoptosis; drug therapy; fractionation; fruits; metastasis; molecular biology; pancreatic neoplasms; radiotherapy; traditional medicine; triterpenoids; viability
Abstract:
... Treatment options for pancreatic cancer (PC) are severely limited due to late diagnosis, early metastasis and the inadequacy of chemotherapy and radiotherapy to combat the aggressive biology of the disease. In recent years, plant-derived bioactive compounds have emerged as a source of novel, anti-cancer agents. Used in traditional medicine worldwide, Elaeocarpus species have reported anti-inflamma ...
DOI:
10.1007/s11033-020-05307-8

19. Application of biocomposite edible coatings based on pea starch and guar gum on quality, storability and shelf life of ‘Valencia’ oranges

Author:
Christopher J. Scarlett,   et al.   ; Bahareh Saberi; John B. Golding; José R. Marques; Penta Pristijono; Suwimol Chockchaisawasdee; Costas E. Stathopoulos;     Show all 7 Authors
Source:
Postharvest biology and technology 2018 v.137 pp. 9-20
ISSN:
0925-5214
Subject:
biocomposites; cell respiration; coatings; edible films; ethanol; ethylene production; firmness; freshness; guar gum; horticulture; hydrophobicity; off flavors; oleic acid; oranges; peas; sensory evaluation; shelf life; starch; waxes; weight loss
Abstract:
... Novel edible composite coatings based on pea starch and guar gum (PSGG), PSGG blended with lipid mixture containing the hydrophobic compounds shellac and oleic acid (PSGG-Sh), and a layer-by-layer (LBL) approach (PSGG as an internal layer and shellac as an external layer), were investigated and compared with a commercial wax (CW) and uncoated fruit on postharvest quality of ‘Valencia’ oranges held ...
DOI:
10.1016/j.postharvbio.2017.11.003

20. Phenolic compounds within banana peel and their potential uses: A review

Author:
Christopher J. Scarlett,   et al.   ; Hang T. Vu; Quan V. Vuong;     Show all 3 Authors
Source:
Journal of functional foods 2018 v.40 pp. 238-248
ISSN:
1756-4646
Subject:
antimicrobial properties; antioxidants; banana peels; bananas; byproducts; pharmaceutical industry; phenolic compounds; wastes
Abstract:
... A large quantity of bananas is produced annually and its peel, which accounts for about one third of the fruit weight, is mostly discarded as waste. The peel has been traditionally used for the treatment of various ailments. This by-product is rich in phenolics with over 40 individual compounds identified. However, composition and levels of these compounds are influenced by various factors, includ ...
DOI:
10.1016/j.jff.2017.11.006