U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Subject "Clostridium" Remove constraint Subject: "Clostridium"
Start Over

Search

8,457  Search Results

« Previous | 1 - 20 of 8,457 |
Number of results to display per page

Search Results

1. Lipid diversity in clostridia

Author:
Guan, Ziqiang; Goldfine, Howard
Source:
Biochimica et biophysica acta 2021 v.1866 no.9 pp. 158966
ISSN:
1388-1981
Subject:
Clostridium beijerinckii; Clostridium botulinum; Clostridium butyricum,   etc   ; Clostridium novyi; antimicrobial peptides; cardiolipins; glycerol; innate immunity; lipidomics; phosphatidylethanolamines;     Show all 10 Subjects
Abstract:
... Studies of the lipidomes of twenty-one species of clostridia have revealed considerable diversity. Even among those species now defined as Clostridium sensu stricto, which are related to Clostridium butyricum, the type species, lipid analysis has shown that a number of distinct clades have characteristic polar lipids. All species of Clostridium sensu stricto have phosphatidylethanolamine, phosphat ...
DOI:
10.1016/j.bbalip.2021.158966

2. Efficient production of recombinant secretory IgA against Clostridium difficile toxins in CHO-K1 cells

Author:
Bhaskara, Venugopal; Leal, Maria Trinidad; Seigner, Jacqueline; Friedrich, Theresa; Kreidl, Emanuel; Gadermaier, Elisabeth; Tesarz, Manfred; Rogalli, Azra; Stangl, Laura; Wallwitz, Jacqueline; Hammel, Katharina; Rothbauer, Mario; Moll, Herwig; Ertl, Peter; Hahn, Rainer; Himmler, Gottfried; Bauer, Anton; Casanova, Emilio
Source:
Journal of biotechnology 2021 v.331 pp. 1-13
ISSN:
0168-1656
Subject:
Clostridium difficile,   etc   ; biotechnology; therapeutics;     Show all 3 Subjects
Abstract:
... Despite the essential role secretory IgAs play in the defense against pathogenic invasion and the proposed value of recombinant secretory IgAs as novel therapeutics, currently there are no IgA-based therapies in clinics. Secretory IgAs are complex molecules and the major bottleneck limiting their therapeutic potential is a reliable recombinant production system. In this report, we addressed this i ...
DOI:
10.1016/j.jbiotec.2021.02.013

3. Changes in treatment of community-onset Clostridioides difficile infection after release of updated guidelines, Atlanta, Georgia, 2018

Author:
Adelman, Max W.; Goodenough, Dana; Sefton, Samantha; Mackey, Carolyn; Thomas, Stepy; Fridkin, Scott K.; Woodworth, Michael H.
Source:
Anaerobe 2021 v.70 pp. 102364
ISSN:
1075-9964
Subject:
Clostridium difficile,   etc   ; guidelines; vancomycin; Georgia;     Show all 4 Subjects
Abstract:
... Updated Clostridioides difficile infection (CDI) guidelines published in 2018 recommend vancomycin as first-line treatment. Of 833 community-onset CDI cases in metropolitan Atlanta, Georgia in 2018, over half did not receive first-line treatment, although guideline adherence increased over the year. Second-line treatment was more common in patients treated in ambulatory settings. ...
DOI:
10.1016/j.anaerobe.2021.102364

4. Did Clostridioides difficile testing and infection rates change during the COVID-19 pandemic?

Author:
Hawes, Armani Minasian; Desai, Angel; Patel, Payal K.
Source:
Anaerobe 2021 v.70 pp. 102384
ISSN:
1075-9964
Subject:
Clostridium difficile,   etc   ; COVID-19 infection; antibiotics;     Show all 3 Subjects
Abstract:
... Testing for and incidence of Clostridioides difficile infection (CDI) was examined at a single center before and during the first surge of the COVID-19 pandemic. Incidence of CDI remained stable but testing statistically significantly decreased during the first surge despite an increase in antibiotic use. There were no new CDI-focused antimicrobial stewardship interventions introduced during this ...
DOI:
10.1016/j.anaerobe.2021.102384

5. Vaccination against pathogenic clostridia in animals: a review

Author:
Abdolmohammadi Khiav, Lida; Zahmatkesh, Azadeh
Source:
Tropical animal health and production 2021 v.53 no.2 pp. 284
ISSN:
0049-4747
Subject:
Clostridium chauvoei; Clostridium novyi; Clostridium perfringens,   etc   ; Clostridium septicum; animal health; botulism; colitis; enterotoxemia; gas gangrene; livestock; necrotic enteritis; spore-forming bacteria; tetanus; vaccination; vaccine development; vaccines;     Show all 16 Subjects
Abstract:
... Clostridium is a Gram-positive, rod-shaped, anaerobic, and spore-forming bacterium, which is found in the surrounding environments throughout the world. Clostridium species cause botulism, tetanus, enterotoxaemia, gas gangrene, necrotic enteritis, pseudomembranous colitis, blackleg, and black disease. Clostridium infection causes severe economic losses in livestock and poultry industries. Vaccinat ...
DOI:
10.1007/s11250-021-02728-w

6. Cyclic Poly(α-peptoid)s by Lithium bis(trimethylsilyl)amide (LiHMDS)-Mediated Ring-Expansion Polymerization: Simple Access to Bioactive Backbones

Author:
Salas-Ambrosio, Pedro; Tronnet, Antoine; Since, Marc; Bourgeade-Delmas, Sandra; Stigliani, Jean-Luc; Vax, Amelie; Lecommandoux, Sébastien; Dupuy, Bruno; Verhaeghe, Pierre; Bonduelle, Colin
Source:
Journal of the American Chemical Society 2021 v.143 no.10 pp. 3697-3702
ISSN:
1520-5126
Subject:
Clostridium difficile,   etc   ; bacteria; cross infection; lithium; polymerization;     Show all 5 Subjects
Abstract:
... Cyclic polymers display unique physicochemical and biological properties. However, their development is often limited by their challenging preparation. In this work, we present a simple route to cyclic poly(α-peptoids) from N-alkylated-N-carboxyanhydrides (NNCA) using LiHMDS promoted ring-expansion polymerization (REP) in DMF. This new method allows the unprecedented use of lysine-like monomers in ...
DOI:
10.1021/jacs.0c13231

7. Isolation of Clostridium perfringens and Clostridioides difficile in diarrheic and nondiarrheic cats

Author:
Silva, Rodrigo Otávio Silveira; Ribeiro, Marcio Garcia; de Paula, Carolina Lechinski; Pires, Isadora Honorato; Oliveira Junior, Carlos Augusto; Diniz, Amanda Nadia; de Araújo Nunes, Talita Augusto; Lobato, Francisco Carlos Faria
Source:
Anaerobe 2020 v.62 pp. 102164
ISSN:
1075-9964
Subject:
Clostridium difficile; Clostridium perfringens,   etc   ; cats; feces; genes;     Show all 5 Subjects
Abstract:
... The occurrence and characteristics of Clostridioides (previously Clostridium) difficile and Clostridium perfringens in the feces of diarrheic and non-diarrheic cats was investigated. Apparently healthy animals were more likely to be positive for C. perfringens type A (p = 0.009). Two isolates (0.7%), one each from a diarrheic and an apparently healthy cat, were positive for the enterotoxin-encodin ...
DOI:
10.1016/j.anaerobe.2020.102164

8. The diagnostic performance and accuracy of 3 molecular assays for the detection of Clostridium difficile in stool samples, compared with the Xpert® C. difficile assay

Author:
Azrad, Maya; Tkhawkho, Linda; Hamo, Zohar; Peretz, Avi
Source:
Journal of microbiological methods 2020 v.168 pp. 105784
ISSN:
0167-7012
Subject:
Clostridium difficile,   etc   ; algorithms; feces;     Show all 3 Subjects
Abstract:
... This research compares the performance and diagnostic accuracy of three molecular tests for the detection of Clostridium difficile in stool samples, with the Xpert® C. difficile assay.Fifty-nine positive and twenty-five stool negative samples were analyzed by the BDmax™ Cdiff, the Simplexa C. difficile Direct, and the GenomEra™ C. difficile, and compared with the Xpert® C. difficile routinely used ...
DOI:
10.1016/j.mimet.2019.105784

9. Using Co-Culture to Functionalize Clostridium Fermentation

Author:
Cui, Yonghao; Yang, Kun-Lin; Zhou, Kang
Source:
Trends in biotechnology 2021 v.39 no.9 pp. 914-926
ISSN:
0167-7799
Subject:
Clostridium,   etc   ; anaerobic treatment; biotechnology; butanol; coculture; fermentation; value added;     Show all 7 Subjects
Abstract:
... Clostridium fermentations have been developed for producing butanol and other value-added chemicals, but their development is constrained by some limitations, such as relatively high substrate cost and the need to maintain an anaerobic condition. Recently, co-culture is emerging as a popular way to address these limitations by introducing a partner strain with Clostridium. Generally speaking, the ...
DOI:
10.1016/j.tibtech.2020.11.016

10. Fe(III) reduction due to low pe+pH contributes to reducing Cd transfer within a soil-rice system

Author:
Li, Shanshan; Lei, Xiaoqin; Qin, Luyao; Sun, Xiaoyi; Wang, Lifu; Zhao, Shuwen; Wang, Meng; Chen, Shibao
Source:
Journal of hazardous materials 2021 v.415 pp. 125668
ISSN:
0304-3894
Subject:
Clostridium,   etc   ; Geobacter; paddy soils; rice; soil water; submergence; tillering;     Show all 7 Subjects
Abstract:
... Effect of Fe redox state caused by low soil pe+pH levels on Cd uptake by rice is unclear. Rice grown in pots of Cd-contaminated paddy soil were subjected to different irrigation regimes: flooding, intermittent flooding (Int-FL), and sustained soil moisture at 70% water holding capacity (WHC). Results showed low pe+pH (5.52 and 7.09) in flooding treatment significantly increased relative abundances ...
DOI:
10.1016/j.jhazmat.2021.125668

11. A neutral red mediated electro-fermentation system of Clostridium beijerinckii for effective co-production of butanol and hydrogen

Author:
Zhang, Yafei; Li, Jianzheng; Meng, Jia; Sun, Kai; Yan, Han
Source:
Bioresource technology 2021 v.332 pp. 125097
ISSN:
0960-8524
Subject:
Clostridium beijerinckii,   etc   ; butanol; carbon; electrodes; fermentation; glucose; hydrogen; hydrogen production;     Show all 8 Subjects
Abstract:
... To enhance the co-production of butanol and hydrogen by the acetone-butanol-ethanol (ABE) fermentation of Clostridium beijerinckii, a novel cathodic electro-fermentation (CEF) system was constructed with neutral red (NR) as electron mediator. With the mediation of NR, production of butanol and hydrogen from glucose in the CEF system achieved 5.49 ± 0.28 g/L and 3.74 ± 0.16 L/L, 569.5% and 325.0% h ...
DOI:
10.1016/j.biortech.2021.125097

12. Changes in STEC and bacterial communities during enrichment of manufacturing beef in selective and non-selective media

Author:
Kang, Sanga; Ravensdale, Joshua T.; Coorey, Ranil; Dykes, Gary A.; Barlow, Robert S.
Source:
Food microbiology 2021 v.96 pp. 103711
ISSN:
0740-0020
Subject:
Clostridium,   etc   ; Escherichia coli O157; beef; food microbiology; peptones; slaughterhouses;     Show all 6 Subjects
Abstract:
... Detection and isolation of Shiga toxin-producing Escherichia coli (STEC) from manufacturing beef is challenging and it may be affected by microbial changes during enrichment. This study was designed to understand population changes during enrichment of beef from an integrated (Samples A and B) and a fragmented (Samples C and D) abattoir. The samples were enriched in buffered peptone water (BPW), A ...
DOI:
10.1016/j.fm.2020.103711

13. Management of excessive gingival display using botulinum toxin type A: a descriptive study

Author:
Andriola, Fernando de Oliveira; Chieza, Gabriela Sperotto; Cavagni, Juliano; Freddo, Angelo Luiz; Corsetti, Adriana
Source:
Toxicon 2021 v.196 pp. 56-62
ISSN:
0041-0101
Subject:
Clostridium botulinum,   etc   ; bacteria; botulinum toxin; descriptive studies; muscles; proteinases;     Show all 6 Subjects
Abstract:
... Botulinum toxin is a protease used by the bacterium Clostridium botulinum that causes chemical denervation of skeletal muscles, producing a temporary weakening of muscle activity. Despite having a transitory effect, the application of botulinum toxin has been identified as an alternative for correcting an excessive gingival display (EGD). However, studies evaluating the maintenance of long-term re ...
DOI:
10.1016/j.toxicon.2021.03.016

14. Trends in Clostridioides difficile diagnosis before and after a change in testing algorithm

Author:
Turner, David P.; Thorburn, Samuel J.; Crowe, Amy; Jardine, Darren; Timmins, Carol
Source:
Journal of microbiological methods 2021 v.184 pp. 106189
ISSN:
0167-7012
Subject:
Clostridium difficile,   etc   ; algorithms; diarrhea; enzyme immunoassays; gene amplification; glutamate dehydrogenase;     Show all 6 Subjects
Abstract:
... Clostridioides difficile (Clostridium difficile) (CD) infection remains a challenging diagnosis in hospitalized patients given the myriad of testing procedures and array of alternative causes for diarrhea. We identified 100 consecutive inpatients with positive CD testing in a single tertiary center before and after changing from nucleic acid amplification testing (NAAT) alone to a two-step algorit ...
DOI:
10.1016/j.mimet.2021.106189

15. Clostridium butyricum Supernatant Regulates the Expression of RORγt in HCT-116 Cells by Inhibiting the TLR2/MyD88/NF-κB Signaling Pathway

Author:
Xie, Ying; Zhou, Linyan; Li, Hui; Li, Yan
Source:
Current microbiology 2021 v.78 no.4 pp. 1543-1550
ISSN:
0343-8651
Subject:
Clostridium butyricum,   etc   ; gene expression; microbiology; protein content; signal transduction;     Show all 5 Subjects
Abstract:
... In this study, we treated HCT-116 cells with Clostridium butyricum (C. butyricum) supernatant and observed its effects on the TLR2/MyD88/NF-κB signaling pathway and RORγt, to further explore the possible immune regulatory mechanism of C. butyricum. Our results showed that C. butyricum supernatant downregulated the mRNA and protein levels of TLR2, MyD88, NF-κBp65, and RORγt in HCT-116 cells and the ...
DOI:
10.1007/s00284-021-02392-1

16. Comparison of Clostridioides difficile strains from animals and humans: First results after introduction of C. difficile molecular typing and characterization at the Istituto Zooprofilattico Sperimentale of Piemonte, Liguria e Valle d’Aosta, Italy

Author:
Tramuta, Clara; Spigaglia, Patrizia; Barbanti, Fabrizio; Bianchi, Daniela Manila; Boteva, Cvetelina; Di Blasio, Alessia; Zoppi, Simona; Zaccaria, Teresa; Proroga, Yolande Thérèse Rose; Chiavacci, Laura; Dondo, Alessandro; Decastelli, Lucia
Source:
Comparative immunology, microbiology, and infectious diseases 2021 v.75 pp. 101623
ISSN:
0147-9571
Subject:
Clostridium difficile,   etc   ; death; humans; immunology; ribotypes; toxins; Italy;     Show all 7 Subjects
Abstract:
... PCR ribotypes (RTs027 and 078) are known causes of Clostridioides difficile infection (CDI) in humans. Molecular typing and characterization of 39 C. difficile strains isolated from samples from humas and animals in 2016–2018 indicated an overlap of RTs between community-acquired patients (CA-CDI) and domestic animals from the same geographical area; 14 RTs were identified: 12 RTs were positive fo ...
DOI:
10.1016/j.cimid.2021.101623

17. Correction: Efficient biomass saccharification using a novel cellobiohydrolase from Clostridium clariflavum for utilization in biofuel industry

Author:
Zafar, Asma; Aftab, Muhammad Nauman; Asif, Anam; Karadag, Ahmet; Peng, Liangcai; Celebioglu, Hasan Ufak; Afzal, Muhammad Sohail; Hamid, Attia; Iqbal, Irfana
Source:
RSC advances 2021 v.11 no.19 pp. 11387
ISSN:
2046-2069
Subject:
Clostridium,   etc   ; bioenergy industry; biomass; cellulose 1,4-beta-cellobiosidase; saccharification;     Show all 5 Subjects
Abstract:
... Correction for ‘Efficient biomass saccharification using a novel cellobiohydrolase from Clostridium clariflavum for utilization in biofuel industry’ by Asma Zafar et al., RSC Adv., 2021, 11, 9246–9261, DOI: 10.1039/D1RA00545F. ...
DOI:
10.1039/d1ra90090k

18. The combined effect on initial glucose concentration and pH control strategies for acetone-butanol-ethanol (ABE) fermentation by Clostridium acetobutylicum DSM 792

Author:
Capilla, M.; San-Valero, P.; Izquierdo, M.; Penya-roja, J.M.; Gabaldón, C.
Source:
Biochemical engineering journal 2021 v.167 pp. 107910
ISSN:
1369-703X
Subject:
Clostridium acetobutylicum,   etc   ; biobutanol; biomass; butanol; fermentation; glucose; hydrolysis; lignocellulose; pH;     Show all 9 Subjects
Abstract:
... The use and depletion of fossil fuels raised the interest in biofuels like biobutanol. Clostridium acetobutylicum DSM 792 is capable of producing biobutanol through ABE fermentation. Butanol production can be influenced by low sugar concentrations, like those obtained after hydrolysis of pre-treated lignocellulosic biomass. This study aimed to evaluate the influence of the initial glucose concentr ...
DOI:
10.1016/j.bej.2020.107910

19. Combined bioaugmentation with electro-biostimulation for improved bioremediation of antimicrobial triclocarban and PAHs complexly contaminated sediments

Author:
Bai, Yang; Liang, Bin; Yun, Hui; Zhao, Youkang; Li, Zhiling; Qi, Mengyuan; Ma, Xiaodan; Huang, Cong; Wang, Aijie
Source:
Journal of hazardous materials 2021 v.403 pp. 123937
ISSN:
0304-3894
Subject:
Clostridium,   etc   ; Desulfobulbus; Ochrobactrum; bioaugmentation; biochemical pathways; electrodes; genes; sediments;     Show all 8 Subjects
Abstract:
... Haloaromatic antimicrobial triclocarban (TCC) is an emerging refractory contaminant that commonly coexisted with conventional contaminants such as polycyclic aromatic hydrocarbons (PAHs). TCC may negatively affect the metabolic activity of sediment microorganisms and persist in environment; however, remediation methods that relieve the TCC inhibitory effect in sediments remain unknown. Here, a nov ...
DOI:
10.1016/j.jhazmat.2020.123937

20. The insufficient extraction of DNA from swine manures may underestimate the abundance of antibiotic resistance genes as well as ignore their potential hosts

Author:
Luo, Ling; Feng, Jinlu; Xue, Rui; Ma, Jianhua; Lou, Liping; He, Jinsong; Liu, Yan; Xiao, Hong; Deng, Ouping; Xie, Liyuan
Source:
Journal of environmental management 2021 v.278 pp. 111587
ISSN:
0301-4797
Subject:
Clostridium,   etc   ; Acinetobacter; antibiotic resistance; environmental management; pig manure; swine;     Show all 6 Subjects
Abstract:
... Swine manure is considered as an extensive reservoir of antibiotic resistance genes (ARGs) spreading in the natural environment after application in soils. To understand whether ARGs abundance in swine manure is underestimated and the hosts are ignored, this study successively extracted DNA from swine manure six times and determined the abundance of several ARGs, class I integron (intI1), and 16S ...
DOI:
10.1016/j.jenvman.2020.111587