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- Cornell, Bruce A., et al. Show all 8 Authors
- Biochimica et biophysica acta 2019 v.1863 no.8 pp. 1243-1253
- cholesterol; computer simulation; dielectric spectroscopy; enzymes; functional properties; ion channels; models; mutants; pH; vertebrates
- ... Sterols have been reported to modulate conformation and hence the function of several membrane proteins. One such group is the Chloride Intracellular Ion Channel (CLIC) family of proteins. The CLIC protein family consists of six evolutionarily conserved protein members in vertebrates. These proteins exist as both monomeric soluble proteins and as membrane bound proteins. To date, the structure of ...