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- Cortés-Ledesma, Felipe, et al. Show all 3 Authors
- Nucleic acids research 2007 v.35 no.19 pp. 6560-6570
- annealing; homologous recombination; nucleic acids; phenotype
- ... Homologous recombination (HR) is the major mechanism used to repair double-strand breaks (DSBs) that result from replication, but a study of repair of DSBs specifically induced during S-phase is lacking. Using an inverted-repeat assay in which a DSB is generated by the encountering of the replication fork with nicks, we can physically detect repair by sister-chromatid recombination (SCR) and intra ...
- PubMed Central:
- Cortés-Ledesma, Felipe, et al. Show all 4 Authors
- Current genetics 2003 v.42 no.4 pp. 185-198
- DNA; DNA repair; DNA replication; Saccharomyces cerevisiae; annealing; chromatids; eukaryotic cells; genotype; homologous recombination; mitosis; mitotic recombination; molecular biology; mycology; nucleotide sequences; proteins; sequence homology; yeasts
- ... Mitotic homologous recombination (HR) is an important mechanism for the repair of double-strand breaks and errors occurring during DNA replication. It is likely that the recombinational repair of DNA lesions occurs preferentially by sister chromatid exchanges that have no genetic consequences. However, most genetically detectable HR events occur between homologous DNA sequences located at allelic ...