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- Costa, Marta H.G., et al. Show all 5 Authors
- Journal of biotechnology 2017 v.262 pp. 28-39
- alginates; anti-inflammatory activity; bone marrow; cell culture; chemotaxis; encapsulation; fibroblasts; humans; microbeads; oxidative stress; reverse transcriptase polymerase chain reaction; stromal cells; tissue repair; tumor necrosis factors
- ... This study proposes to use alginate encapsulation as a strategy to assess the paracrine activity of 3D- and 2D-cultured human bone marrow mesenchymal stem/stromal cells (BM MSC) in the setting of wound repair and regeneration processes. A side-by-side comparison of MSC culture in three different 3D configurations (spheroids, encapsulated spheroids and encapsulated single cells) versus 2D monolayer ...