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- Author:
- Curtis P. Van Tassell, et al. ; Yahui Gao; Lingzhao Fang; Ransom L. Baldwin; Erin E. Connor; John B. Cole; Li Ma; Cong-jun Li; George E. Liu; Show all 9 Authors
- Source:
- Genomics 2021 v.113 no.4 pp. 2045-2055
- ISSN:
- 0888-7543
- Subject:
- Holstein; animal production; body conformation; calves; cell cycle; chromium; dairy cattle; epithelial cells; epithelium; genes; genomics; humans; mice; stomach; transcriptomics
- Abstract:
- ... Using the 10× Genomics Chromium Controller, we obtained scRNA-seq data of 5064 and 1372 individual cells from two Holstein calf ruminal epithelial tissues before and after weaning, respectively. We detected six distinct cell clusters, designated their cell types, and reported their marker genes. We then examined these clusters' underlining cell types and relationships by performing cell cycle, pse ...
- DOI:
- 10.1016/j.ygeno.2021.04.039
- https://doi.org/10.1016/j.ygeno.2021.04.039
2. Genome-wide CNV analysis revealed variants associated with growth traits in African indigenous goats
- Author:
- Curtis P. Van Tassell, et al. ; Mei Liu; Jennifer Woodward-Greene; Xiaolong Kang; Michael G. Pan; Benjamin Rosen; Hong Chen; George E. Liu; Show all 8 Authors
- Source:
- Genomics 2020 v.112 no.2 pp. 1477-1480
- ISSN:
- 0888-7543
- Subject:
- gene dosage; gene ontology; genes; genetic variation; genotype-phenotype correlation; goat breeds; goats; growth traits; indigenous species; meat production; regression analysis; reproductive traits; single nucleotide polymorphism
- Abstract:
- ... Using the CaprineSNP50 data generated by the AGIN consortium, we detected common CNVs in 126 samples from four African indigenous goat breeds. A total of 30 CNVs ranging from 30,237 bp to 4,910,757 bp were identified. These CNVs were then associated with six growth traits by a linear regression analysis. Three significant associations were identified between two CNVs and two body traits after fals ...
- Handle:
- 10113/6616200
- DOI:
- 10.1016/j.ygeno.2019.08.018
- CHORUS:
- 10.1016/j.ygeno.2019.08.018
- https://doi.org/10.1016/j.ygeno.2019.08.018
- Author:
- Curtis P. Van Tassell, et al. ; Wilson Kaumbata; Liveness Banda; Gábor Mészáros; Timothy Gondwe; M.J. Woodward-Greene; Benjamin D. Rosen; Johann Sölkner; Maria Wurzinger; Show all 9 Authors
- Source:
- Small ruminant research 2020 v.187 pp. 106095
- ISSN:
- 0921-4488
- Subject:
- breeding programs; capital; cattle; chickens; data collection; economic sustainability; flocks; funding; goats; household income; households; hunger; monitoring; rearing; rural economics; rural poverty; small farms; socioeconomics; swine; Malawi
- Abstract:
- ... A study was conducted to determine tangible and intangible benefits of local goats to smallholders in low input crop-livestock production system where community-based goat breeding program (goat CBBP) is being implemented. Data was collected through a 12-month flock and household (137 households) monitoring study between August 2017 to July 2018. Data collected was analyzed using enterprise budget ...
- DOI:
- 10.1016/j.smallrumres.2020.106095
- CHORUS:
- 10.1016/j.smallrumres.2020.106095
- https://doi.org/10.1016/j.smallrumres.2020.106095
4. VarGoats project: a dataset of 1159 whole-genome sequences to dissect Capra hircus global diversity
- Author:
- Curtis P. Van Tassell, et al. ; Laure Denoyelle; Estelle Talouarn; Philippe Bardou; Licia Colli; Adriana Alberti; Coralie Danchin; Marcello Del Corvo; Stéfan Engelen; Céline Orvain; Isabelle Palhière; Rachel Rupp; Julien Sarry; Mazdak Salavati; Marcel Amills; Emily Clark; Paola Crepaldi; Thomas Faraut; Clet Wandui Masiga; François Pompanon; Benjamin D. Rosen; Alessandra Stella; Gwenola Tosser-Klopp; The VarGoats Consortium; Show all 24 Authors
- Source:
- Genetics, selection, evolution 2021 v.53 no.1 pp. 86
- ISSN:
- 1297-9686
- Subject:
- Capra hircus; data collection; domestication; evolution; genetic variation; genome; genomics; goats; hybridization; prediction; provenance; trees; Africa; Asia; Caribbean; Europe; Pacific Ocean Islands
- Abstract:
- ... BACKGROUND: Since their domestication 10,500 years ago, goat populations with distinctive genetic backgrounds have adapted to a broad variety of environments and breeding conditions. The VarGoats project is an international 1000-genome resequencing program designed to understand the consequences of domestication and breeding on the genetic diversity of domestic goats and to elucidate how speciatio ...
- DOI:
- 10.1186/s12711-021-00659-6
- https://doi.org/10.1186/s12711-021-00659-6
- Author:
- Curtis P. Van Tassell, et al. ; Lingzhao Fang; Yang Zhou; Shuli Liu; Jicai Jiang; Derek M. Bickhart; Daniel J. Null; Bingjie Li; Steven G. Schroeder; Benjamin D. Rosen; John B. Cole; Li Ma; George E. Liu; Show all 13 Authors
- Source:
- Epigenomes 2019 v.3 no.2 pp. -
- ISSN:
- 2075-4655
- Subject:
- DNA; DNA methylation; cattle; embryogenesis; genome-wide association study; genomics; homeotic genes; humans; livestock and meat industry; male fertility; males; microRNA; prediction; spermatozoa
- Abstract:
- ... Decreased male fertility is a big concern in both human society and the livestock industry. Sperm DNA methylation is commonly believed to be associated with male fertility. However, due to the lack of accurate male fertility records (i.e., limited mating times), few studies have investigated the comprehensive impacts of sperm DNA methylation on male fertility in mammals. In this study, we generate ...
- DOI:
- 10.3390/epigenomes3020010
- CHORUS:
- 10.3390/epigenomes3020010
- https://doi.org/10.3390/epigenomes3020010
- Author:
- Curtis P. Van Tassell, et al. ; Shuli Liu; Xiaolong Kang; Claudia R. Catacchio; Mei Liu; Lingzhao Fang; Steven G. Schroeder; Wenli Li; Benjamin D. Rosen; Daniela Iamartino; Leopoldo Iannuzzi; Tad S. Sonstegard; Mario Ventura; Wai Yee Low; John L. Williams; Derek M. Bickhart; George E. Liu; Show all 17 Authors
- Source:
- Functional & integrative genomics 2019 v.19 no.3 pp. 409-419
- ISSN:
- 1438-793X
- Subject:
- Bubalus bubalis; buffaloes; cattle; comparative genomic hybridization; copy number variation; evolution; fluorescence in situ hybridization; genes; genome-wide association study; high-throughput nucleotide sequencing; immune response; oxygen; phenotype; prediction; quantitative polymerase chain reaction; regression analysis; selection methods; sensory system; signal transduction
- Abstract:
- ... Duplicated sequences are an important source of gene evolution and structural variation within mammalian genomes. Using a read depth approach based on next-generation sequencing, we performed a genome-wide analysis of segmental duplications (SDs) and associated copy number variations (CNVs) in the water buffalo (Bubalus bubalis). By aligning short reads of Olimpia (the reference water buffalo) to ...
- DOI:
- 10.1007/s10142-019-00657-4
- CHORUS:
- 10.1007/s10142-019-00657-4
- https://doi.org/10.1007/s10142-019-00657-4
- Author:
- Curtis P. Van Tassell, et al. ; Gordon L. Spangler; Benjamin D. Rosen; Moses Babatunde Ilori; Olivier Hanotte; Eui-Soo Kim; Tad S. Sonstegard; Joan M. Burke; James L.M. Morgan; David R. Notter; Show all 10 Authors
- Source:
- PloS one 2017 v.12 no.6 pp. 16-32
- ISSN:
- 1932-6203
- Subject:
- Barbados Blackbelly; ancestry; drug resistance; ecotypes; gastrointestinal nematodes; genome; humans; introgression; phylogeny; population structure; production costs; provenance; sheep; sheep industry; single nucleotide polymorphism; trade; wool; Africa; Caribbean; Europe; South America; United States
- Abstract:
- ... Hair sheep of Caribbean origin have become an important part of the U.S. sheep industry. Their lack of wool eliminates a number of health concerns and drastically reduces the cost of production. More importantly, Caribbean hair sheep demonstrate robust production performance even in the presence of drug-resistant gastrointestinal nematodes, a rising concern to the industry. Despite the growing imp ...
- Handle:
- 10113/5931470
- DOI:
- 10.1371/journal.pone.0179021
- PubMed:
- 28662044
- PubMed Central:
- PMC5490989
- https://doi.org/10.1371/journal.pone.0179021
- Author:
- Curtis P. Van Tassell, et al. ; Derek M. Bickhart; Mick Watson; Sergey Koren; Kevin Panke-Buisse; Laura M. Cersosimo; Maximilian O. Press; Jo Ann S. Van Kessel; Bradd J. Haley; Seon Woo Kim; Cheryl Heiner; Garret Suen; Kiranmayee Bakshy; Ivan Liachko; Shawn T. Sullivan; Phillip R. Myer; Jay Ghurye; Mihai Pop; Paul J. Weimer; Adam M. Phillippy; Timothy P. L. Smith; Show all 21 Authors
- Source:
- Genome biology 2019 v.20 no.1 pp. 153
- ISSN:
- 1474-760X
- Subject:
- alleles; antibiotic resistance genes; bacteriophages; cattle; hosts; microbial communities; rumen microorganisms
- Abstract:
- ... We describe a method that adds long-read sequencing to a mix of technologies used to assemble a highly complex cattle rumen microbial community, and provide a comparison to short read-based methods. Long-read alignments and Hi-C linkage between contigs support the identification of 188 novel virus-host associations and the determination of phage life cycle states in the rumen microbial community. ...
- DOI:
- 10.1186/s13059-019-1760-x
- PubMed:
- 31375138
- PubMed Central:
- PMC6676630
- CHORUS:
- 10.1186/s13059-019-1760-x
- https://doi.org/10.1186/s13059-019-1760-x
- Author:
- Curtis P. Van Tassell, et al. ; Lingyang Xu; Yali Hou; Derek M. Bickhart; Jiuzhou Song; Tad S. Sonstegard; George E. Liu; Show all 7 Authors
- Source:
- Functional & integrative genomics 2014 v.14 no.2 pp. 333-339
- ISSN:
- 1438-793X
- Subject:
- Angus; cattle; gastrointestinal nematodes; gastrointestinal system; gene expression; genes; haplotypes; linear models; linkage disequilibrium; nematode infections; regression analysis; single nucleotide polymorphism; surveys
- Abstract:
- ... Gastrointestinal (GI) nematode infections are a worldwide threat to human health and animal production. In this study, we performed a genome-wide association study between copy number variations (CNVs) and resistance to GI nematodes in an Angus cattle population. Using a linear regression analysis, we identified one deletion CNV which reaches genome-wide significance after Bonferroni correction. W ...
- DOI:
- 10.1007/s10142-014-0371-6
- PubMed:
- 24718732
- https://doi.org/10.1007/s10142-014-0371-6
- Author:
- Curtis P. Van Tassell, et al. ; Matthew C. McClure; Derek Bickhart; Dan Null; Paul VanRaden; Lingyang Xu; George Wiggans; George Liu; Steve Schroeder; Jarret Glasscock; Jon Armstrong; John B. Cole; Tad S. Sonstegard; Show all 13 Authors
- Source:
- PloS one 2014 v.9 no.3 pp. 1-9
- ISSN:
- 1932-6203
- Subject:
- Brown Swiss; DNA repair; Holstein; Jersey; cattle; cell division; chromosomes; embryogenesis; exons; genotyping; haplotypes; sequence analysis; single nucleotide polymorphism
- Abstract:
- ... The recent discovery of bovine haplotypes with negative effects on fertility in the Brown Swiss, Holstein, and Jersey breeds has allowed producers to identify carrier animals using commercial single nucleotide polymorphism (SNP) genotyping assays. This study was devised to identify the causative mutations underlying defective bovine embryo development contained within three of these haplotypes (Br ...
- Handle:
- 10113/58860
- DOI:
- 10.1371/journal.pone.0092769
- PubMed:
- 24667746
- PubMed Central:
- PMC3965462
- https://doi.org/10.1371/journal.pone.0092769
- Author:
- Curtis P. Van Tassell, et al. ; Eui-Soo Kim; John B. Cole; Heather Huson; George R. Wiggans; Brian A. Crooker; George Liu; Yang Da; Tad S. Sonstegard; Zhanjiang Liu; Show all 10 Authors
- Source:
- PloS one 2013 v.8 no.11 pp. -
- ISSN:
- 1932-6203
- Subject:
- Holstein; animal breeding; artificial insemination; artificial selection; cattle; genome; haplotypes; homozygosity; inbreeding coefficient; loci; milk; milk fat yield; milk protein yield; quantitative trait loci; United States
- Abstract:
- ... The intensive selection programs for milk made possible by mass artificial insemination increased the similarity among the genomes of North American (NA) Holsteins tremendously since the 1960s. This migration of elite alleles has caused certain regions of the genome to have runs of homozygosity (ROH) occasionally spanning millions of continuous base pairs at a specific locus. In this study, genome ...
- Handle:
- 10113/58857
- DOI:
- 10.1371/journal.pone.0080813
- PubMed:
- 24348915
- PubMed Central:
- PMC3858116
- https://doi.org/10.1371/journal.pone.0080813
- Author:
- Curtis P. Van Tassell, et al. ; Ana M. Pérez O’Brien; Gábor Mészáros; Yuri T. Utsunomiya; Tad S. Sonstegard; J. Fernando Garcia; Roberto Carvalheiro; Marcos V.B. da Silva; Johann Sölkner; Show all 9 Authors
- Source:
- Livestock science 2014 v.166 pp. 121-132
- ISSN:
- 1871-1413
- Subject:
- alleles; animal breeding; animal genetics; cattle; gene frequency; genomics; genotype; genotyping; linkage disequilibrium; loci; single nucleotide polymorphism; taurine; zebu; zebu breeds
- Abstract:
- ... Linkage disequilibrium (LD), the observed correlation between alleles at different loci in the genome, is a determinant parameter in many applications of molecular genetics. With the wider use of genomic technologies in animal breeding and animal genetics, it is worthwhile revising and improving the current knowledge and understanding of cattle LD.This study analyzes levels of LD assessed through ...
- DOI:
- 10.1016/j.livsci.2014.05.007
- https://doi.org/10.1016/j.livsci.2014.05.007
- Author:
- Curtis P Van Tassell, et al. ; Roberto Carvalheiro; Solomon A Boison; Haroldo H R Neves; Mehdi Sargolzaei; Flavio S Schenkel; Yuri T Utsunomiya; Ana Maria Pérez O’Brien; Johann Sölkner; John C McEwan; Tad S Sonstegard; José Fernando Garcia; Show all 12 Authors
- Source:
- Genetics, selection, evolution 2014 v.46 no.1 pp. 69
- ISSN:
- 0999-193X
- Subject:
- Nellore; bulls; computer software; cost effectiveness; cows; gene frequency; genetic markers; genotype; genotyping; linkage disequilibrium; marker-assisted selection; prediction; single nucleotide polymorphism; sires; zebu; zebu breeds
- Abstract:
- ... BACKGROUND: Genotype imputation from low-density (LD) to high-density single nucleotide polymorphism (SNP) chips is an important step before applying genomic selection, since denser chips tend to provide more reliable genomic predictions. Imputation methods rely partially on linkage disequilibrium between markers to infer unobserved genotypes. Bos indicus cattle (e.g. Nelore breed) are characteriz ...
- DOI:
- 10.1186/s12711-014-0069-1
- PubMed:
- 25927950
- PubMed Central:
- PMC4192291
- https://doi.org/10.1186/s12711-014-0069-1
- Author:
- Curtis P Van Tassell, et al. ; Ana M Pérez O’Brien; Yuri T Utsunomiya; Gábor Mészáros; Derek M Bickhart; George E Liu; Tad S Sonstegard; Marcos VB Da Silva; José Fernando Garcia; Johann Sölkner; Show all 10 Authors
- Source:
- Genetics, selection, evolution 2014 v.46 no.1 pp. 2607
- ISSN:
- 0999-193X
- Subject:
- Angus; Brown Swiss; Nellore; beef cattle; genes; genetic variation; genome assembly; linkage disequilibrium
- Abstract:
- ... BACKGROUND: Signatures of selection are regions in the genome that have been preferentially increased in frequency and fixed in a population because of their functional importance in specific processes. These regions can be detected because of their lower genetic variability and specific regional linkage disequilibrium (LD) patterns. METHODS: By comparing the differences in regional LD variation b ...
- DOI:
- 10.1186/1297-9686-46-19
- PubMed:
- 24592996
- PubMed Central:
- PMC4014805
- https://doi.org/10.1186/1297-9686-46-19
- Author:
- Curtis P. Van Tassell, et al. ; Francesca Bertolini; Bertrand Servin; Andrea Talenti; Estelle Rochat; Eui Soo Kim; Claire Oget; Isabelle Palhière; Alessandra Crisà; Gennaro Catillo; Roberto Steri; Marcel Amills; Licia Colli; Gabriele Marras; Marco Milanesi; Ezequiel Nicolazzi; Benjamin D. Rosen; Bernt Guldbrandtsen; Tad S. Sonstegard; Gwenola Tosser-Klopp; Alessandra Stella; Max F. Rothschild; Stéphane Joost; Paola Crepaldi; the AdaptMap consortium; Show all 25 Authors
- Source:
- Genetics, selection, evolution 2018 v.50 no.1 pp. 57
- ISSN:
- 0999-193X
- Subject:
- artificial selection; circadian clocks; climatic factors; color; data collection; domestication; genes; genotyping; geographical coordinates; geographical distribution; glucose; goat breeds; goats; humans; oxidative stress; phenotype; stress response
- Abstract:
- ... BACKGROUND: Since goat was domesticated 10,000 years ago, many factors have contributed to the differentiation of goat breeds and these are classified mainly into two types: (i) adaptation to different breeding systems and/or purposes and (ii) adaptation to different environments. As a result, approximately 600 goat breeds have developed worldwide; they differ considerably from one another in term ...
- DOI:
- 10.1186/s12711-018-0421-y
- PubMed:
- 30449276
- PubMed Central:
- PMC6240954
- https://doi.org/10.1186/s12711-018-0421-y
- Author:
- Curtis P. Van Tassell, et al. ; Tad S. Sonstegard; John B. Cole; Paul M. VanRaden; Daniel J. Null; Steven G. Schroeder; Derek Bickhart; Matthew C. McClure; Marinus FW. te. Pas; Show all 9 Authors
- Source:
- PloS one v.8 no.1 pp. -
- ISSN:
- 1932-6203
- Subject:
- Jersey; abortion (animals); alleles; ancestry; breeding; bulls; dairy cattle; embryonic mortality; haplotypes; homozygosity; lethal genes; nonsense mutation; nucleotide sequences; recessive genes; reproductive efficiency; sequence analysis; single nucleotide polymorphism
- Abstract:
- ... With the recent advent of genomic tools for cattle, several recessive conditions affecting fertility have been identified and selected against, such as deficiency of uridine monophosphate synthase, complex vertebral malformation, and brachyspina. The current report refines the location of a recessive haplotype affecting fertility in Jersey cattle using crossover haplotypes, discovers the causative ...
- Handle:
- 10113/57095
- DOI:
- 10.1371/journal.pone.0054872
- PubMed:
- 23349982
- PubMed Central:
- PMC3551820
- https://doi.org/10.1371/journal.pone.0054872
- Author:
- Curtis P. Van Tassell, et al. ; Yali Hou; George E. Liu; Derek M. Bickhart; Lakshmi K. Matukumalli; Congjun Li; Jiuzhou Song; Louis C. Gasbarre; Tad S. Sonstegard; Show all 9 Authors
- Source:
- Functional & Integrative Genomics 2012 v.12 no.1 pp. 81-92
- ISSN:
- 1438-7948
- Subject:
- Angus; breeding value; digestive system diseases; disease resistance; gastrointestinal nematodes; gene dosage; gene expression regulation; genetic variation; genome; genotyping; host-pathogen relationships; immune response; nematode infections; phenotypic variation; resistance mechanisms; single nucleotide polymorphism
- Abstract:
- ... Genomic structural variation is an important and abundant source of genetic and phenotypic variation. We previously reported an initial analysis of copy number variations (CNVs) in Angus cattle selected for resistance or susceptibility to gastrointestinal nematodes. In this study, we performed a large-scale analysis of CNVs using SNP genotyping data from 472 animals of the same population. We dete ...
- Handle:
- 10113/56870
- DOI:
- 10.1007/s10142-011-0252-1
- PubMed:
- 21928070
- https://doi.org/10.1007/s10142-011-0252-1
- Author:
- Curtis P. Van Tassell, et al. ; Licia Colli; Marco Milanesi; Andrea Talenti; Francesca Bertolini; Minhui Chen; Alessandra Crisà; Kevin Gerard Daly; Marcello Del Corvo; Bernt Guldbrandtsen; Johannes A. Lenstra; Benjamin D. Rosen; Elia Vajana; Gennaro Catillo; Stéphane Joost; Ezequiel Luis Nicolazzi; Estelle Rochat; Max F. Rothschild; Bertrand Servin; Tad S. Sonstegard; Roberto Steri; Paolo Ajmone-Marsan; Paola Crepaldi; Alessandra Stella; the AdaptMap Consortium; Show all 25 Authors
- Source:
- Genetics, selection, evolution 2018 v.50 no.1 pp. 58
- ISSN:
- 0999-193X
- Subject:
- domestication; gene flow; gene pool; genetic improvement; genetic variation; genomics; goats; humans; introgression; major genes; mountains; reproductive isolation; single nucleotide polymorphism; Europe; Morocco; West Asia
- Abstract:
- ... BACKGROUND: Goat populations that are characterized within the AdaptMap project cover a large part of the worldwide distribution of this species and provide the opportunity to assess their diversity at a global scale. We analysed genome-wide 50 K single nucleotide polymorphism (SNP) data from 144 populations to describe the global patterns of molecular variation, compare them to those observed in ...
- DOI:
- 10.1186/s12711-018-0422-x
- PubMed:
- 30449284
- PubMed Central:
- PMC6240949
- https://doi.org/10.1186/s12711-018-0422-x
- Author:
- Curtis P. Van Tassell, et al. ; Benjamin D. Rosen; Derek M. Bickhart; Robert D. Schnabel; Sergey Koren; Christine G. Elsik; Elizabeth Tseng; Troy N. Rowan; Wai Y. Low; Aleksey Zimin; Christine Couldrey; Richard Hall; Wenli Li; Arang Rhie; Jay Ghurye; Stephanie D. McKay; Françoise Thibaud-Nissen; Jinna Hoffman; Brenda M. Murdoch; Warren M. Snelling; Tara G. McDaneld; John A. Hammond; John C Schwartz; Wilson Nandolo; Darren E. Hagen; Christian Dreischer; Sebastian J. Schultheiss; Steven G. Schroeder; Adam M. Phillippy; John B. Cole; George Liu; Timothy P. L. Smith; Juan F. Medrano; Show all 33 Authors
- Source:
- GigaScience 2020 v.9 no.3 pp. 1-9
- ISSN:
- 2047-217X
- Subject:
- cattle; genes; genomics; nucleotide sequences; proteins; sequence analysis; technology; wills
- Abstract:
- ... Background Major advances in selection progress for cattle have been made following the introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos taurus reference genome (UMD3.1.1), which was created using now-outdated technologies and is hindered by a variety of deficiencies and inaccuracies. Results We present the new reference genome for cattle, ARS-UCD1.2, based ...
- DOI:
- 10.1093/gigascience/giaa021
- CHORUS:
- 10.1093/gigascience/giaa021
- https://doi.org/10.1093/gigascience/giaa021
- Author:
- Curtis P. Van Tassell, et al. ; Ludmilla B. Zavarez; Yuri T. Utsunomiya; Adriana S. Carmo; Haroldo H. R. Neves; Roberto Carvalheiro; Maja Ferencakovic; Ana M. Perez O'Brien; Ino Curik; John B. Cole; Marcos V. G. B. da Silva; Tad S. Sonstegard; Johann Solkner; Jose F. Garcia; Show all 14 Authors
- Source:
- Frontiers in genetics 2015 v.6 no.5 pp. -
- ISSN:
- 1664-8021
- Subject:
- Nellore; beef cattle; carcass weight; cattle breeding; chromosomes; cows; genome; homozygosity; inbreeding; reproductive traits; single nucleotide polymorphism; sires; zebu; Brazil
- Abstract:
- ... The use of relatively low numbers of sires in cattle breeding programs, particularly on those for carcass and weight traits in Nellore beef cattle (Bos indicus) in Brazil, has always raised concerns about inbreeding, which affects conservation of genetic resources and sustainability of this breed. Here, we investigated the distribution of autozygosity levels based on runs of homozygosity (ROH) in ...
- Handle:
- 10113/60883
- DOI:
- 10.3389/fgene.2015.00005
- PubMed:
- 25688258
- PubMed Central:
- PMC4310349
- https://doi.org/10.3389/fgene.2015.00005