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- Cybulski, Larisa E., et al. Show all 4 Authors
- Journal of molecular biology 2019 v.431 no.5 pp. 1016-1024
- biotechnology; dimerization; engineering; histidine kinase; hydrogen bonding; temperature
- ... To address the mechanism of thermosensing and its implications for molecular engineering, we previously deconstructed the functional components of the bacterial thermosensor DesK, a histidine kinase with a five-span transmembrane domain that detects temperature changes. The system was first simplified by building a sensor that consists of a single chimerical transmembrane segment that retained ful ...