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- Dai, Hong-Ying, et al. Show all 12 Authors
- Food and chemical toxicology 2018 v.112 pp. 194-204
- Trifolium pratense; acetylcysteine; antioxidants; apoptosis; biochanin A; caspase-3; caspase-9; cell growth; chemoprevention; cytochrome c; cytotoxicity; dose response; doxorubicin; glutathione; humans; membrane potential; mitochondria; mitochondrial membrane; mitogen-activated protein kinase; osteosarcoma; phosphatidylserines; toxicology; vitamin E
- ... Biochanin A is a major isoflavone in red clover and a potent chemopreventive agent against cancer. However, the effects of biochanin A on human osteosarcoma cells have never been clarified. This study investigated the anti-proliferative potential of biochanin A in osteosarcoma cells. The results indicate that biochanin A inhibited cell growth and colony formation in a dose-dependent manner with a ...