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- Davidson, Benjamin P., et al. Show all 5 Authors
- European journal of biochemistry 2000 v.267 no.1 pp. 61-67
- agarose; animal models; biosynthesis; calcium; calcium oxalate; crystals; gel electrophoresis; gene expression; genes; glyceraldehyde-3-phosphate dehydrogenase; humans; kidneys; liver; messenger RNA; pathogenesis; prothrombin; rats; reverse transcriptase polymerase chain reaction; sequence analysis; thrombin; urinary calculi; urine
- ... There is considerable interest in determining the role of prothrombin fragments, especially urinary prothrombin fragment 1 (UPTF1), in the pathogenesis of calcium oxalate (CaOx) urinary calculi. This fragment is present in abundance in the matrix of CaOx crystals generated in human urine in vitro and has also been detected in human urinary stones containing calcium. More recently, prothrombin gene ...