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- Desbordes, L., et al. Show all 7 Authors
- Veterinary microbiology 2009 v.137 no.3-4 pp. 306-312
- animal diseases; human diseases; salmonellosis; Salmonella enterica subsp. enterica; strains; mutants; mutation; molecular genetics; molecular epidemiology; screening; phenotype; gene frequency; genes; sequence analysis; binding proteins; DNA-binding proteins; binding properties; DNA repair; virulence; Salmonella enterica subsp. enterica serovar Heidelberg
- ... Hypermutation is an important mechanism used by different Salmonella enterica subspecies enterica to regulate genetic stability in adaptation to changing environments, including antimicrobial treatments and industrial processes. Strong hypermutator strains generally contain a mutation in genes of the methyl mismatch repair (MMR) system and have mutation frequencies up to 1000-fold higher than wild ...